Clinical trials
Cognitive Health clinical trials
Below are recruiting cognitive health clinical trials, each written for real people, not researchers. We’re tracking 283 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05748613Recruiting
Anxiety-focused skills training for people with Alzheimer’s
This study tests a treatment aimed at reducing anxiety in people who have Alzheimer’s disease or related memory problems. It also involves a support partner, and the goal is to see whether the program can lower anxiety and stress day-to-day.
Tallahassee, FloridaAges 60 years+ - NCT06758414Recruiting
CBT for chronic pain in veterans with serious mental illness
This trial tests a type of talk therapy called Cognitive Behavioral Therapy for Chronic Pain, designed for veterans with serious mental illness. It aims to help you manage back pain and improve your quality of life.
Baltimore, MarylandAges 18 years+ - NCT07106593Recruiting
Talk therapy for PTSD and tinnitus after concussion
This study tests a type of talk therapy for people with both PTSD and chronic tinnitus that started after a mild head injury. The therapy aims to help reduce symptoms of both conditions together.
San Antonio, TexasAges 18 years+ - NCT07222280Recruiting
Alzheimer's dementia and brain inflammation trial
This trial tests if treating brain inflammation can help older adults hospitalized with sudden confusion or cognitive issues. It may help those without a prior dementia diagnosis but who have toxic or metabolic causes for their symptoms.
Crossville, TennesseeAges 60–90 - NCT07279714RecruitingPhase 2
Fisetin for mild Alzheimer's disease
This trial tests whether a supplement called fisetin can help people with mild Alzheimer's disease or mild cognitive impairment. Fisetin is a natural compound found in fruits and vegetables that may reduce aging-related changes in the body.
Toronto, OntarioAges 60 years+ - NCT05079464Recruiting
Exercise plus brain stimulation to improve memory in early impairment
This trial tests whether a supervised exercise program, paired with brain stimulation, can improve thinking and memory in people with early “vascular” cognitive problems (not dementia). It may help your brain function before memory loss becomes more severe.
Toronto, OntarioAges 50 years+ - NCT05591027RecruitingPhase 1
Testing Centella asiatica for memory problems in older adults
This Phase 1 study tests whether Centella asiatica (a plant-based supplement) is safe and reaches its intended target in people with mild cognitive impairment or early Alzheimer’s disease. It also checks how it affects memory-related brain measures like MRI scans, which is why multiple scans are required.
Portland, OregonAges 60–85 - NCT07071350RecruitingPhase 2/Phase 3
Optimizing heart rate for persistent concussion symptoms in military veterans
This trial tests a treatment designed to improve heart rate variability, which may help reduce long-term concussion symptoms like headaches, dizziness, and trouble sleeping. It is for military veterans who have had a mild concussion more than a year ago and still have ongoing symptoms.
Richmond, VirginiaAges 18 years+ - NCT07603102Recruiting
Mindfulness and Walking Training for Memory After Stroke
This study tests whether combining mindfulness meditation with balance and walking exercises can help improve memory and thinking skills in people who had a stroke. The trial focuses on people with mild cognitive impairment—difficulty thinking clearly—after stroke recovery.
NanjingAges 55 years+ - NCT06709027Enrolling by invitation
Mobile health program for depression in older adults
This study is testing a smartphone-based health program designed for older adults with depression. The program aims to help you manage your mood and track changes in thinking and memory using a mobile app.
Fuzhou, FujianAges 60 years+ - NCT06684444Enrolling by invitationPhase 4
Sleep coaching study for firefighters with sleep troubles
This study tests if health coaching can help career firefighters sleep better. You'll have private coaching sessions by phone or computer.
Tucson, ArizonaAges 18 years+ - NCT07081282Recruiting
Study on frailty and thinking decline in older adults
This study looks at how to better understand and predict frailty and memory changes in older adults with at least one chronic condition. It aims to use a simple screening to personalize care and help you stay independent longer.
SingaporeAges 60–85 - NCT05380050Recruiting
Telehealth vs in-person skills training for brain injury and PTSD
This study compares a combined skills program delivered by video/phone (telehealth) versus meeting in person. It aims to improve attention and coping skills for veterans who have both mild brain injury and PTSD.
Gainesville, FloridaAges 30–55 - NCT05595577Recruiting
Personalized exercise program to improve fitness during cancer care
This trial tests whether a tailored, home-based exercise plan can improve exercise capacity (how far and how safely you can be active) in people receiving cancer treatments that may affect the heart. It may help you build safer stamina while monitoring your heart health.
Winston-Salem, North CarolinaAges 18–85 - NCT05597124RecruitingPhase 2
Exercise program to improve brain health in older Black adults
This Phase 2 study tests whether a structured exercise program can improve brain health in adults age 60 and older who are less active and have early thinking/memory concerns. It may help maintain or improve thinking abilities over time, with medical supervision throughout the study.
Newark, New JerseyAges 60 years+ - NCT07557381Recruiting
Game-Based Brain Training for Schizophrenia
This study tests whether playing games on a smartphone or tablet can help improve memory, attention, and thinking skills in people with schizophrenia. Researchers will track how the game-based training affects cognitive abilities over time.
ShanghaiAges 18–45 - NCT07243600Recruiting
Brain Training for Memory in Mild Cognitive Impairment
This study tests a computer-based brain-training program designed to improve memory and thinking skills in older adults with mild cognitive impairment (MCI). It aims to see if these exercises can help keep the brain healthy and slow down memory decline.
Montreal, QuebecAges 65 years+ - NCT06731452Recruiting
Brain health study with MRI and TMS
This study looks at brain activity patterns in healthy adults. You'll have an MRI and a non-invasive brain stimulation session (TMS) to help researchers understand how the brain works. If you're already in The BrainHealth Project, this is a chance to learn more about your own brain health.
Dallas, TexasAges 22–100 - NCT06623682Recruiting
Online mental health support for university students
This trial tests a self-help program with support services for students in Hong Kong who are experiencing moderate to severe anxiety or depression. It aims to see if these tools can improve mental health.
Hong KongAges 18 years+ - NCT07176273Recruiting
Personalized PTSD Treatment for Veterans
This trial helps veterans with PTSD choose between two proven talk therapies—Prolonged Exposure (PE) or Cognitive Processing Therapy (CPT)—and uses a smartphone app to support their treatment. The goal is to see which approach works best for each person.
Augusta, GeorgiaAges 18 years+ - NCT07042087Recruiting
Brain health lifestyle study: timed eating and mindfulness
This study tests whether a combination of time-restricted eating and mindfulness can help protect brain health in people with early memory concerns. It lasts 9 months and includes regular guidance and support.
BrnoAges 60–80 - NCT07109245RecruitingPhase 4
Do antipsychotics block insulin action in the brain?
This study tests whether a single dose of a common antipsychotic medication affects how the brain responds to insulin, which could help explain weight gain and metabolic side effects. Healthy young adults will receive either the antipsychotic or a placebo, then have their brain activity measured with an MRI.
Toronto, OntarioAges 18–35 - NCT07223346Recruiting
Fitness and therapy for Latina cancer survivors
This trial offers a program combining exercise and mental health support for Latina women in Colorado who have recently finished cancer treatment or are still undergoing it. It aims to improve well-being through group sessions focused on physical activity and coping skills.
Fort Collins, ColoradoAges 18 years+ - NCT05048680Recruiting
Breathing low-oxygen training to support brain blood flow in seniors
This study tests whether brief “low-oxygen” conditioning can improve blood flow to the brain and overall cerebrovascular (brain blood vessel) health in older adults. It may help people who are generally less active, as long as they have no major medical or safety barriers for the training.
La Tronche, Auvergne-Rhône-AlpesAges 60–80
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Common questions
- Are there clinical trials for cognitive health?
- Yes. Clin2 currently lists 283 recruiting cognitive health studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cognitive health trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cognitive health trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.