Clinical trials
Cognitive Impairment clinical trials
Below are recruiting cognitive impairment clinical trials, each written for real people, not researchers. We’re tracking 575 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06703541Recruiting
Alzheimer's disease research study with brain scans and spinal tap
This study at Duke University is looking for people aged 25 to 80 who may be at risk for Alzheimer's disease. It involves brain scans (MRI and PET) and a spinal tap to learn more about the disease and find better ways to detect and treat it early.
Durham, North CarolinaAges 25–80 - NCT07445841Recruiting
Exercise to protect the brain after a first stroke
This trial tests whether a structured exercise program can help prevent thinking and memory problems after a first stroke. It might help you keep your brain healthy if you join within the first six months after your stroke.
Hamilton, OntarioAges 40–80 - NCT06982261Recruiting
Voice assistant program for older adults with mild memory concerns
This study tests a voice technology program to help older adults manage their health at home. If you have mild memory issues, live alone, and meet income guidelines, you might be eligible.
Atlanta, GeorgiaAges 55 years+ - NCT06741553Recruiting
Studying lecanemab for early Alzheimer's disease
This study looks at how well lecanemab works for people with early Alzheimer's disease. It aims to see if the drug can help slow down memory and thinking problems.
Hangzhou, ZhejiangAges Up to 85 years - NCT06757569Recruiting
New PET scan for detecting amyloid plaques in the brain
This study tests a newer, shorter PET scan to see if it can detect amyloid plaques (sticky protein clumps linked to memory loss) as well as the standard scan. It may help diagnose cognitive problems with less time in the scanner.
Toronto, OntarioAges 18 years+ - NCT06783283Recruiting
Brain stimulation to improve memory in mild cognitive impairment
This trial tests whether a gentle electrical brain stimulation technique called tACS can improve working memory in people with mild cognitive impairment (MCI). If you have MCI due to early Alzheimer's, this study may help find new ways to boost memory.
Toronto, OntarioAges 60 years+ - NCT06832839Recruiting
Cognitive impairment in moyamoya disease study
This study looks at why some people with moyamoya disease have trouble with thinking and memory. It may help find better ways to understand and treat these problems.
Beijing, ChinaAges 18–60 - NCT06835595Recruiting
Brain signals as markers of thinking changes in Parkinson's
This study uses a safe, noninvasive brain stimulation method (transcranial magnetic stimulation, or TMS) to look at brain signals related to thinking and memory in people with Parkinson's disease. The goal is to find a better way to measure cognitive changes over time.
Trieste, Friuli Venezia GiuliaAges 18 years+ - NCT06850597RecruitingPhase 2
Testing dimethyl fumarate for early Alzheimer's disease
This study tests a drug called dimethyl fumarate to see if it can help people with early Alzheimer's disease. It may slow down memory loss and thinking problems.
Lodz, Łódź VoivodeshipAges 55–90 - NCT06857539Recruiting
Assessing thinking and movement in high-risk infants
This study looks at how high-risk infants (especially those born early or with brain concerns) develop their thinking and movement skills over time, comparing them to healthy babies. The goal is to better understand and support their development.
CorkAges birth–4 months - NCT06863727Recruiting
Beijing disability survey in older adults
This study is a survey that follows older adults in Beijing over time to track disability. It aims to understand how disabilities develop in the community, which could help improve care for older people.
BeijingAges 65 years+ - NCT06869135Recruiting
Saliva testing for brain diseases
This trial is collecting saliva samples from people with Alzheimer's, Parkinson's, or other brain diseases to find new ways to diagnose them. It may help improve early detection.
Florence, FIAges 45 years+ - NCT06869850Recruiting
Special milk-enriched food for children with severe malnutrition
This study tests a special food to help children with severe malnutrition recover. The food is a peanut-based paste with added milk fat globule membrane, which may help kids gain weight and get stronger.
Bandajuma, PujehunAges 6 months–4.9 years - NCT06912321Recruiting
Brain Circuit Study for Type 2 Diabetes
This study uses MRI scans to look at a specific brain circuit (the Papez loop) in people with type 2 diabetes. It aims to understand how diabetes might affect brain networks related to memory and emotion.
Nanjing, JiangsuAges 45–70 - NCT06916221Recruiting
Digital brain training in aging
This study tests whether a digital intervention can help older adults (60+) maintain or improve cognitive function. It is designed for healthy adults or those with mild cognitive impairment (MCI), and people who do not regularly play a musical instrument or have extensive music training.
San Francisco, CaliforniaAges 60–85 - NCT06918704Recruiting
Digital brain health program for older adults
This study tests a digital program designed to help support thinking and memory in older adults. It may be a good fit if you are 60+ and generally healthy, even if you have some mild memory concerns.
San Francisco, CaliforniaAges 60–85 - NCT06930560Recruiting
Hearing aids for dementia with mood or behavior issues
This study tests whether providing hearing aids to older adults with Alzheimer's or related dementias can reduce troubling symptoms like agitation or depression. If you have untreated hearing loss and a caregiver who can join you, this trial may help improve quality of life.
Baltimore, MarylandAges 60–100 - NCT06935812Recruiting
Comparing hand exercises and VR for memory problems
This study compares three types of exercises (using both hands, finger movements, and virtual reality) in people with mild memory loss to see which helps thinking and memory best.
Famagusta, Eyalet/YerleşkeAges 50–75 - NCT06962111Recruiting
Partner in Care Living Alone Plus study for early-stage dementia
This study tests a workshop to help people with early-stage memory problems who live alone. If you have mild dementia or mild cognitive impairment and can join Zoom sessions, you may be eligible.
Phoenix, ArizonaAges 60 years+ - NCT06968039Recruiting
Personalized brain stimulation for cognitive issues in demyelinating diseases
This trial tests a personalized form of electrical brain stimulation to improve cognitive problems like memory and thinking speed in people with conditions that damage the protective coating around nerves. It aims to see if this treatment can help with day-to-day thinking challenges.
Beijing, Beijing MunicipalityAges 18–65 - NCT06976203RecruitingPhase 3
Testing karxt for thinking problems in alzheimer's
This trial tests if a combination medicine, KarXT plus KarX-EC, can help with thinking and memory problems in people with mild to moderate Alzheimer's disease. It aims to see if the treatment is safe and effective.
Fullerton, CaliforniaAges 60–85 - NCT06983119Recruiting
Finding early signs of memory loss in Pavia
This study looks for early thinking and memory changes in people 50 and older who haven't been diagnosed with cognitive decline. You'll complete a quick assessment to see if further checkups might help.
Pavia, PaviaAges 18 years+ - NCT06989619Recruiting
Sleep and mindfulness program for older adults in residential housing
This study uses peer support and group activities to help older adults living in residential facilities improve their sleep and practice mindfulness (a type of focused relaxation). If you're 55+ and live in a residential building, you may be able to join.
Boston, MassachusettsAges 55 years+ - NCT07012993RecruitingPhase 2
Very low dose PET brain scan study
This study tests whether using a very low dose of radiation for a brain PET scan can still give clear images. If you are eligible, you will get a type of radioactive tracer that helps show amyloid plaques in the brain, often used in Alzheimer's research.
Englewood, New JerseyAges 18–120
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Common questions
- Are there clinical trials for cognitive impairment?
- Yes. Clin2 currently lists 575 recruiting cognitive impairment studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cognitive impairment trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cognitive impairment trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.