Clinical trials
Cognitive Impairment clinical trials
Below are recruiting cognitive impairment clinical trials, each written for real people, not researchers. We’re tracking 575 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06453980Recruiting
Brain plasticity study in mild memory loss
This study looks at how the brain changes in people with mild memory problems. It uses brain scans and a gentle, non-invasive electrical stimulation to see if we can improve brain function.
Ann Arbor, MichiganAges 60 years+ - NCT06467539RecruitingPhase 2
New combination treatment for early Alzheimer's or memory loss
This trial tests a new combination treatment (DAOIB and an antioxidant) for people with early Alzheimer's or mild cognitive impairment. It aims to see if the treatment can help slow or improve memory and thinking problems.
Kaohsiung CityAges 50–90 - NCT06482749Recruiting
Magnetic brain stimulation for better recovery after surgery
This study tests whether magnetic brain stimulation before and after surgery can help older adults with mild memory or thinking problems recover their thinking abilities faster. You would receive either real or sham stimulation for a few days around your surgery.
Beijing, Beijing MunicipalityAges 65 years+ - NCT07432009Recruiting
Hip replacement and confusion risk in older adults
This study looks at whether older adults who get a hip replacement may experience confusion after surgery. It aims to find factors that might help prevent or reduce this confusion.
BrnoAges 65 years+ - NCT06489548RecruitingPhase 2
Foralumab for Early Alzheimer's Disease
This study tests an experimental drug called Foralumab, which aims to calm overactive immune cells in the brain linked to Alzheimer's. It may help slow memory loss in people with early-stage Alzheimer's.
Boston, MassachusettsAges 60–85 - NCT06500910Recruiting
Exercise for heart and brain health in premature children
This study tests whether a supervised exercise program can help children born prematurely (before 32 weeks) improve their heart health and thinking skills. It's designed for children ages 6 to 12 who are otherwise healthy and not receiving special education for attention problems.
Basel, Canton of Basel-CityAges 6–12 - NCT06502964RecruitingPhase 2
ALTO-101 study for schizophrenia cognitive symptoms
This study tests an experimental medication called ALTO-101 for people with schizophrenia who also have cognitive impairment (memory or thinking problems). It aims to see if the drug can improve these symptoms while you continue your current antipsychotic treatment.
Garden Grove, CaliforniaAges 21–55 - NCT06507488Recruiting
Daphnetin Capsule for Mild Cognitive Issues From Blood Vessels
This trial tests a capsule called daphnetin for people with mild thinking and memory problems linked to blood vessel health. The goal is to see if it helps improve or slow down these changes.
Shenyang, LiaoningAges 50–80 - NCT06529744Recruiting
Using blood tests to better diagnose early dementia
This study is testing whether simple blood tests can help doctors better understand the type and progression of memory or thinking problems in people with early dementia. It aims to improve confidence in the diagnosis and future outlook.
North York, OntarioAges 30–95 - NCT06538311RecruitingEarly Phase 1
TMS treatment for early Alzheimer's disease
This study tests whether a non-invasive brain stimulation treatment called TMS (transcranial magnetic stimulation) can help people with early Alzheimer's disease or related memory problems. It's a safe, gentle way to stimulate brain cells using magnetic pulses.
Boston, MassachusettsAges 40–99 - NCT06541834Recruiting
Predicting diabetes eye nerve problems with retina scans
This study uses artificial intelligence to analyze retinal images and predict the risk of nerve-related problems caused by diabetes. It may help identify those at risk before symptoms appear.
MilanAges 45 years+ - NCT06548191RecruitingPhase 1
Time-Restricted Eating for Alzheimer's Disease
This study tests whether a time-restricted eating schedule (eating all meals within a 10-hour window each day) can improve memory and thinking in people with early Alzheimer's disease or mild cognitive impairment. Healthy partners of people with memory problems can also join as a comparison group.
San Diego, CaliforniaAges 60 years+ - NCT06572748Recruiting
Cooking study for older adults with memory concerns
This study tests a cooking program called Chef Anchor 3.0 for older adults with mild memory problems or dementia. It looks at whether learning to cook can help with thinking skills and daily life.
Hong KongAges 60 years+ - NCT06584110Recruiting
Buddy-up exercise program for dementia and caregiver
This study tests a buddy-up program where a person with mild to early moderate dementia and their family caregiver do physical activities together using video calls. It aims to see if exercising together helps both their health and well-being.
Hong KongAges 18 years+ - NCT06592352RecruitingPhase 2
Modafinil for thinking problems in MS
This study tests whether the medication modafinil can improve thinking and memory problems in people with MS. If you have MS and notice cognitive changes like forgetfulness or trouble focusing, you may be eligible.
BragaAges 18–64 - NCT06596746Recruiting
Tracking markers for neurodegenerative diseases
This study tracks changes in people with Parkinson's disease, other movement disorders, or cognitive decline to find better ways to measure disease progression.
Cassino, FrosinoneAges 10 years+ - NCT07485725Recruiting
Digital tools study for health decisions
This study tests if digital tools can help older adults make better healthcare decisions. You’ll use a website to search for health information and share your thoughts in interviews.
Tallahassee, FloridaAges 60 years+ - NCT07220538RecruitingPhase 4
Ginkgo biloba for memory problems after a mild stroke
This trial tests whether adding ginkgo biloba extract tablets to standard stroke care helps improve memory and thinking in people who had a mild stroke. You may join if you are 55 or older, had a mild stroke in the last 1 to 2 weeks, and now have some cognitive difficulties.
AnyangAges 55 years+ - NCT04938349Recruiting
Dual-task training for memory and balance in older adults
This trial tests a type of training that challenges you to do two tasks at once to help with thinking and movement. It is for people over 55 who may have mild memory problems but do not have major brain, heart, or lung conditions.
Chicago, IllinoisAges 55 years+ - NCT06618872Recruiting
Comparing tau and amyloid PET scans for memory problems
This study compares two types of brain PET scans (tau and amyloid) to see which one better helps diagnose memory problems. You may be eligible if you have mild cognitive impairment or mild dementia and your doctor has already ordered an amyloid PET scan.
Geneva, Canton of GenevaAges 50–85 - NCT06619613RecruitingPhase 1
Study of CM383 for early Alzheimer's disease
This trial tests a new drug called CM383 in people with mild cognitive impairment or mild Alzheimer's disease. The goal is to see if it can help slow down memory loss.
HefeiAges 50–85 - NCT06639282RecruitingPhase 2
Testing siponimod for mild Alzheimer's dementia
This study tests if a medicine called siponimod, already used for multiple sclerosis, can help people with mild Alzheimer's dementia. You will take a pill daily and be monitored closely for safety and cognitive changes.
Phoenix, ArizonaAges 50–85 - NCT06652828Recruiting
Treadmill training to prevent falls in older adults
This study tests a special treadmill training that gently pushes you off balance to help you learn to catch yourself and prevent falls. It is for older adults who are at high risk of falling.
Heidelberg, Baden-WurttembergAges 70 years+ - NCT06664229Recruiting
Dementia and fall prevention program for older adults
This study tests a pressure sensor-based program to help prevent dementia and falls in older adults. If you are 65 or older, can walk independently, and have no dementia or other conditions that affect thinking, you may be able to join.
Seoul, SeoulAges 65 years+
Hear when a new Cognitive Impairment trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for cognitive impairment?
- Yes. Clin2 currently lists 575 recruiting cognitive impairment studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cognitive impairment trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cognitive impairment trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.