Clinical trials
Cognitive Impairment clinical trials
Below are recruiting cognitive impairment clinical trials, each written for real people, not researchers. We’re tracking 571 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06930560Recruiting
Hearing aids for dementia with mood or behavior issues
This study tests whether providing hearing aids to older adults with Alzheimer's or related dementias can reduce troubling symptoms like agitation or depression. If you have untreated hearing loss and a caregiver who can join you, this trial may help improve quality of life.
Baltimore, MarylandAges 60–100 - NCT06916221Recruiting
Digital brain training in aging
This study tests whether a digital intervention can help older adults (60+) maintain or improve cognitive function. It is designed for healthy adults or those with mild cognitive impairment (MCI), and people who do not regularly play a musical instrument or have extensive music training.
San Francisco, CaliforniaAges 60–85 - NCT06918704Recruiting
Digital brain health program for older adults
This study tests a digital program designed to help support thinking and memory in older adults. It may be a good fit if you are 60+ and generally healthy, even if you have some mild memory concerns.
San Francisco, CaliforniaAges 60–85 - NCT06888219Enrolling by invitation
Acupuncture for Swallowing and Tube Removal After Brain Injury
This study tests if acupuncture on the ear and body can help people with severe brain injuries regain the ability to swallow safely and have their breathing tube removed. It's for patients who are at least 1 month but no more than 3 months after a stroke or brain bleed.
FlorenceAges 18 years+ - NCT06869135Recruiting
Saliva testing for brain diseases
This trial is collecting saliva samples from people with Alzheimer's, Parkinson's, or other brain diseases to find new ways to diagnose them. It may help improve early detection.
Florence, FIAges 45 years+ - NCT06869850Recruiting
Special milk-enriched food for children with severe malnutrition
This study tests a special food to help children with severe malnutrition recover. The food is a peanut-based paste with added milk fat globule membrane, which may help kids gain weight and get stronger.
Bandajuma, PujehunAges 6 months–4.9 years - NCT06857539Recruiting
Assessing thinking and movement in high-risk infants
This study looks at how high-risk infants (especially those born early or with brain concerns) develop their thinking and movement skills over time, comparing them to healthy babies. The goal is to better understand and support their development.
CorkAges birth–4 months - NCT06835595Recruiting
Brain signals as markers of thinking changes in Parkinson's
This study uses a safe, noninvasive brain stimulation method (transcranial magnetic stimulation, or TMS) to look at brain signals related to thinking and memory in people with Parkinson's disease. The goal is to find a better way to measure cognitive changes over time.
Trieste, Friuli Venezia GiuliaAges 18 years+ - NCT06826157Enrolling by invitation
Brain Wave Patterns in Early Memory Loss and Dementia
This study uses an advanced EEG (electroencephalogram) to measure brain wave activity in people with early Alzheimer's, frontotemporal dementia, or Lewy body dementia. It aims to find patterns that could help doctors better understand the disease and predict how it might progress.
Milan, ItalyAges 50–85 - NCT05983809Recruiting
Balance and walking rehab using technology for MS
This trial tests a new type of balance and walking training for people with multiple sclerosis. It uses technology to help improve your stability and gait, which may help you move more safely and confidently.
Roma, RMAges 18–65 - NCT05710549Recruiting
Brain study of autobiographical memory using brain stimulation
This study looks at how the brain supports remembering your own past experiences. It tests brain mechanisms using brain scanning (MRI) and noninvasive brain stimulation to see how these memory processes work.
Geneva, Canton of GenevaAges 18–85 - NCT05065450Recruiting
Testing whether brain stimulation improves memory in epilepsy
This trial looks at ways to improve memory by targeting specific deep brain areas in people with epilepsy. You may be eligible if you are already scheduled for long-term video monitoring with implanted depth electrodes in the memory-related regions (amygdala, hippocampus, and nearby areas).
St Louis, MissouriAges 18–75 - NCT06634147Recruiting
Exercise program to prevent decline in hospitalized older adults
This study is testing a gentle exercise program for older adults (75+) while they are in the hospital. The goal is to see if it helps prevent loss of strength, memory, or thinking skills.
Pamplona, NavarreAges 75 years+ - NCT06783283Recruiting
Brain stimulation to improve memory in mild cognitive impairment
This trial tests whether a gentle electrical brain stimulation technique called tACS can improve working memory in people with mild cognitive impairment (MCI). If you have MCI due to early Alzheimer's, this study may help find new ways to boost memory.
Toronto, OntarioAges 60 years+ - NCT04946916Recruiting
Testing blood/brain marker levels and thinking problems in psychiatric illness
This study looks at neurofilament light (a brain/nerve injury marker) and how it relates to thinking and memory problems in people with certain psychiatric conditions. It may help researchers understand brain changes and cognitive impairment, which could guide better diagnosis in the future.
BronAges 45–80 - NCT05697588Recruiting
Study blood and brain markers from mild memory loss to dementia
This study looks for “biomarkers” (measurable signs from blood and brain tests) that may help predict who with mild cognitive impairment (MCI) could later develop dementia. Results may help doctors spot risk earlier and better plan care.
Beijing, Beijing MunicipalityAges 50–85 - NCT06761066Enrolling by invitation
Testing NVP-NK4146 for mild cognitive impairment due to Alzheimer's
This study tests a new medicine, NVP-NK4146, for people with mild cognitive impairment (MCI) due to Alzheimer's disease. The goal is to see if it can help slow down memory and thinking problems.
SeoulAges 60 years+ - NCT06757569Recruiting
New PET scan for detecting amyloid plaques in the brain
This study tests a newer, shorter PET scan to see if it can detect amyloid plaques (sticky protein clumps linked to memory loss) as well as the standard scan. It may help diagnose cognitive problems with less time in the scanner.
Toronto, OntarioAges 18 years+ - NCT06254469RecruitingPhase 3
PET scan study for memory decline with head injury or Alzheimer's risk
This trial uses a special PET scan tracer to see if it can predict who will get worse over time. It is for people with mild memory or thinking problems that may be linked to past head injuries or early Alzheimer's disease.
Evanston, IllinoisAges 45 years+ - NCT06482749Recruiting
Magnetic brain stimulation for better recovery after surgery
This study tests whether magnetic brain stimulation before and after surgery can help older adults with mild memory or thinking problems recover their thinking abilities faster. You would receive either real or sham stimulation for a few days around your surgery.
Beijing, Beijing MunicipalityAges 65 years+ - NCT06741553Recruiting
Studying lecanemab for early Alzheimer's disease
This study looks at how well lecanemab works for people with early Alzheimer's disease. It aims to see if the drug can help slow down memory and thinking problems.
Hangzhou, ZhejiangAges Up to 85 years - NCT06723015Enrolling by invitationPhase 2
Tau PET in anti-amyloid therapy for Alzheimer's
This study uses brain scans to see how anti-amyloid treatments affect tau protein buildup in people with early Alzheimer's. If you have mild cognitive impairment or mild Alzheimer's, you may be eligible to help understand how these treatments work.
Rochester, MinnesotaAges 50–90 - NCT06722976Enrolling by invitation
Digital health and exercise for staying independent longer
This trial tests a program that combines digital health tools with exercise to help older adults stay active and independent. It may be a good fit if you are 65 or older and can walk or move around without major difficulty.
Covilha, CovilhãAges 60 years+ - NCT06703541Recruiting
Alzheimer's disease research study with brain scans and spinal tap
This study at Duke University is looking for people aged 25 to 80 who may be at risk for Alzheimer's disease. It involves brain scans (MRI and PET) and a spinal tap to learn more about the disease and find better ways to detect and treat it early.
Durham, North CarolinaAges 25–80
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Common questions
- Are there clinical trials for cognitive impairment?
- Yes. Clin2 currently lists 571 recruiting cognitive impairment studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cognitive impairment trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cognitive impairment trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.