Clinical trials
Cognitive Impairment clinical trials
Below are recruiting cognitive impairment clinical trials, each written for real people, not researchers. We’re tracking 575 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07058688RecruitingPhase 2
Testing a new drug for Alzheimer's (NTRX-07)
This study tests an experimental drug for Alzheimer's called NTRX-07. It aims to see if it can slow memory decline for people with mild to moderate Alzheimer's.
BrnoAges 65–80 - NCT07083089Recruiting
Hearing and thinking in early Alzheimer's and Parkinson's
This trial studies how hearing relates to early memory and movement problems in Alzheimer's and Parkinson's diseases. It may help find new ways to detect and track these conditions.
MontpellierAges 50–85 - NCT07083154RecruitingPhase 3
Testing a dual-action drug for diabetes and early memory loss
This study tests if a new type of diabetes drug that targets two natural hormones can help people with type 2 diabetes who also have early memory problems. If you have type 2 diabetes and mild cognitive impairment or mild dementia, this trial may offer a potential treatment option.
Changsha, HunanAges 50–75 - NCT07087873Recruiting
Testing brain stimulation for memory problems in inflammatory diseases
This trial tests if a gentle electrical current applied to the scalp can improve memory and thinking in people with certain inflammatory conditions that affect the brain and spinal cord.
Beijing, Beijing MunicipalityAges 18–60 - NCT07089303Recruiting
Alzheimer's brain imaging study (AD-MINER)
This study uses advanced brain imaging to learn more about Alzheimer's disease. It looks at people with normal memory, mild memory problems, or Alzheimer's dementia to find better ways to diagnose and track the disease.
Beijing, Beijing MunicipalityAges 55–90 - NCT07112521Recruiting
Brain stimulation for thinking problems after breast cancer
This study tests whether a gentle brain stimulation technique called tDCS can help with thinking and memory problems after breast cancer treatment. It compares women with and without obesity to see if the treatment works differently.
Helsinki, UusimaaAges 18 years+ - NCT07120347Recruiting
Remote sensors to study daily activities in older adults with mild memory loss
This study uses remote sensors (like motion detectors) to see how older adults with mild memory or thinking problems go about their daily lives. It may help researchers learn how to better support people with early dementia.
Columbia, MissouriAges 50 years+ - NCT07139171Recruiting
Plasma exosome role in thinking problems in first-episode schizophrenia
This study looks at tiny particles called exosomes in your blood and how small molecules inside them called microRNAs may affect thinking and memory in people with a first episode of schizophrenia. If you join, your blood will be used to help find new ways to understand and treat cognitive symptoms.
TianjinAges 18–65 - NCT07154394Recruiting
Heart amyloid and function in Alzheimer's disease
This study examines whether amyloid plaques in the heart affect heart function in people with Alzheimer's disease. It uses brain amyloid PET and MRI scans to explore a potential link.
Essen, North Rhine-WestphaliaAges 18 years+ - NCT07154511RecruitingPhase 1/Phase 2
Tributyrin for Parkinson's with memory problems
This trial tests a supplement called tributyrin to see if it can help with thinking and memory problems in people with Parkinson's disease. You may be able to join if you have both Parkinson's and mild cognitive impairment or dementia.
Ann Arbor, MichiganAges 45 years+ - NCT07220668RecruitingPhase 1/Phase 2
Safety check for older adults in senior living
This trial tests a new program called Sense4Safety to help prevent falls and keep seniors living independently. It uses a simple physical test and a memory screening to see if you're eligible.
Philadelphia, PennsylvaniaAges 65 years+ - NCT07226219RecruitingPhase 1
Methylphenidate for Attention in Sickle Cell Disease
This trial tests if a medication called methylphenidate can help children with sickle cell disease who have trouble with attention, focus, or executive function. It aims to see if it can improve daily life and school performance.
Memphis, TennesseeAges 8–17 - NCT07237009Recruiting
Personalized reminiscence therapy for memory loss
This trial tests a digital app that uses personal photos and memories to help people with early memory problems feel less depressed or apathetic. It's designed for seniors who have mild cognitive impairment or early dementia.
AngersAges 60 years+ - NCT07272811Recruiting
Computer memory testing for early Alzheimer's signs
This study uses a computer-based platform to test memory and thinking in healthy adults and in people with mild memory concerns (called aMCI). The goal is to better understand how memory changes with age and to spot early signs of Alzheimer's disease.
Milan, ItalyAges 55–80 - NCT07314892Recruiting
Psychiatric health and symptom severity in GvHD patients
This study looks at how graft-versus-host disease (a complication after a bone marrow transplant) affects mental health and symptom severity. It aims to understand the connection so that doctors can better support patients.
Gdansk, Pomeranian VoivodeshipAges 18–75 - NCT07342075Recruiting
Registry Study of Small Vessel Disease in the Brain
This study tracks people with cerebral small vessel disease (changes in the brain's tiny blood vessels) to learn more about how the condition progresses. It may be a good fit if you are 50 or older and have had an MRI showing these changes.
Beijing, Beijing MunicipalityAges 50 years+ - NCT02420470Recruiting
An early warning system for diabetic brain changes
This study tests whether an “early warning” approach can detect early changes in the brain related to diabetes before serious problems happen. If you qualify, you may be asked to take part in brain and health assessments to see how well the system works.
Xi'an, ShaanxiAges 40–65 - NCT02795052Recruiting
Stem cell treatment trial for nerve injury
This study tests whether bone-marrow stem cells can improve nerve function in people with nerve damage that usually doesn’t recover with current care. It also checks whether the treatment is safe and whether people can be followed over time with repeated nerve exams.
Westport, ConnecticutAges 18 years+ - NCT02670161Enrolling by invitationPhase 4
Using electronic records to improve care for brain and nerve conditions
This study looks at how doctors use electronic medical records to improve treatment and care for people with certain brain and nervous system conditions. It may help because it tests practice-based approaches across neurology visits.
Evanston, IllinoisAges 18–100 - NCT00585572Enrolling by invitation
Wisconsin Brain Donor Program for research after death
This program collects donated brain tissue and related samples after death to help researchers study brain diseases. You may be eligible if you’re an approved family member of a specific study participant, or you meet certain health and consent requirements.
Madison, WisconsinAges 18 years+ - NCT01453127Enrolling by invitationPhase 4
DaTscan scan for aging and movement brain conditions
This trial uses a special brain scan called DaTscan to study how certain brain conditions change with aging and over time. It may help researchers better understand movement and other neurodegenerative conditions and who may benefit from future treatments.
Rochester, MinnesotaAges 40–90 - NCT07443514Recruiting
Thinking and memory in people with DLBCL
This study looks at how thinking and memory may be affected in people newly diagnosed with a type of lymphoma called diffuse large B-cell lymphoma (DLBCL) who are about to start a common chemotherapy regimen known as R-CHOP. It also includes a comparison group of healthy relatives. The goal is to understand how treatment may affect cognitive function over time.
LjubljanaAges 18 years+ - NCT07454824Recruiting
Aligning medications with what matters most: patient portal trial
This study tests whether a patient portal tool can help older adults with memory problems and their care partners adjust medications to better match their personal goals and values. It is for people who are 65 or older, have mild cognitive impairment or dementia, are taking a medication that may not be ideal for their age, and use the patient portal.
Baltimore, MarylandAges 65 years+ - NCT07466394Recruiting
Early detection of thinking problems study
This study tests a new way to find early signs of memory or thinking problems in older adults. It could help identify people who might benefit from earlier support or treatment.
MünchenAges 60 years+
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Common questions
- Are there clinical trials for cognitive impairment?
- Yes. Clin2 currently lists 575 recruiting cognitive impairment studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cognitive impairment trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cognitive impairment trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.