Clinical trials
Cognitive clinical trials
Below are recruiting cognitive clinical trials, each written for real people, not researchers. We’re tracking 2,028 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06702488RecruitingPhase 1
Dexmedetomidine and magnesium to protect thinking after surgery in seniors
This study tests whether adding two drugs, dexmedetomidine and magnesium sulfate, during anesthesia can help older adults keep their thinking and memory sharp after open abdominal surgery. It aims to reduce the risk of confusion or memory problems that sometimes happen after surgery.
Al FayyumAges 60–80 - NCT06703320Recruiting
Virtual reality pathfinding study for stroke recovery
This study uses a virtual reality pathfinding game to see how your brain activates after a stroke. It may help doctors understand how to improve recovery.
Chongqing, Chongqing MunicipalityAges 18–80 - NCT06703307Recruiting
Brain markers for stroke-related thinking changes
This study uses a special brain scanning technique (fNIRS) to look for markers that show how stroke affects thinking. Both people who have had a stroke and healthy volunteers can join.
Chongqing, Chongqing MunicipalityAges 18–80 - NCT06703541Recruiting
Alzheimer's disease research study with brain scans and spinal tap
This study at Duke University is looking for people aged 25 to 80 who may be at risk for Alzheimer's disease. It involves brain scans (MRI and PET) and a spinal tap to learn more about the disease and find better ways to detect and treat it early.
Durham, North CarolinaAges 25–80 - NCT06704451Recruiting
IL-33 and memory after major abdominal surgery
This study looks at whether a protein called IL-33 is linked to memory and thinking problems that can happen after major abdominal surgery. It may help doctors find patients at risk earlier.
Kunming, YunnanAges Any age - NCT06705816Recruiting
Cognitive function in Rett syndrome during trofinetide treatment
This study looks at how trofinetide (a medicine for Rett syndrome) affects thinking and memory in people with Rett syndrome. It will follow participants who are starting this treatment through a specific clinic.
Minneapolis, MinnesotaAges 18–99 - NCT05283811Recruiting
Brain recording during epilepsy care, while doing a memory task
This study listens to brain activity in people with epilepsy who already need electrodes placed inside the brain. Researchers want to understand how different parts of the brain respond while you complete simple thinking and memory-related tasks, which may help improve future treatments.
Los Angeles, CaliforniaAges 10–64 - NCT07445841Recruiting
Exercise to protect the brain after a first stroke
This trial tests whether a structured exercise program can help prevent thinking and memory problems after a first stroke. It might help you keep your brain healthy if you join within the first six months after your stroke.
Hamilton, OntarioAges 40–80 - NCT07685262Recruiting
Bright light therapy for better daytime function in students
This trial tests if morning bright light therapy can help university students feel more awake and function better during the day. You may be eligible if you live in shared student housing and don't have a diagnosed sleep problem.
Hung HomAges 18 years+ - NCT06982261Recruiting
Voice assistant program for older adults with mild memory concerns
This study tests a voice technology program to help older adults manage their health at home. If you have mild memory issues, live alone, and meet income guidelines, you might be eligible.
Atlanta, GeorgiaAges 55 years+ - NCT07390045Recruiting
Exercise and mental training for older cancer survivors
This study tests whether exercise and mental exercises can help older cancer survivors who notice memory or thinking problems. You'll take part in a program that combines physical activity with brain training to see if it improves your day-to-day life.
Rochester, New YorkAges 65 years+ - NCT06710418Recruiting
Comparing two red blood cell transfusion thresholds for people with high-grade myeloid neoplasms, AML or B-ALL
This study compares two different strategies for when to give red blood cell transfusions to people receiving intensive chemotherapy or stem cell transplant for high-grade myeloid neoplasms, AML or B-ALL. The goal is to see which approach better improves quality of life and daily function.
Seattle, WashingtonAges 18 years+ - NCT06711432Recruiting
Blood Pressure Management During Tumor Surgery and Brain Function
This trial compares different blood pressure management strategies during abdominal tumor surgery to see which one better protects cognitive function (thinking, memory, and clarity). It is for patients who have multiple stroke risk factors and are undergoing a lengthy surgery.
Hangzhou, ZhejiangAges 40–85 - NCT06717165Recruiting
Brain stimulation with talk therapy for OCD
This study tests if adding a gentle brain stimulation technique (tACS) to cognitive behavioral therapy (CBT) can help reduce OCD symptoms more than CBT alone. It is for adults with OCD who have not completed a full course of CBT before.
Shanghai, Shanghai MunicipalityAges 18–60 - NCT06720246Recruiting
Weight loss surgery and liraglutide study on thinking and long-term weight
This trial tests whether bariatric surgery or the drug liraglutide helps people with obesity lose weight and keep it off by looking at how it affects your thinking and behavior. It might help you understand which treatment works best for long-term success.
Milan, MilanAges 20–60 - NCT06721429Recruiting
Dual-task training for balance and health in type 2 diabetes
This trial tests whether doing two tasks at once (like walking while talking) can improve balance, exercise ability, thinking, and quality of life for people with type 2 diabetes. It compares this training to standard care to see if it offers extra benefits.
BartınAges 65 years+ - NCT06721819RecruitingPhase 3
Sleep and brain training before heart surgery to prevent delirium
This study tests whether a combination of sleep therapy, brain games, and light exercise before heart surgery can help prevent confusion or disorientation (delirium) after the operation. Participants will be asked to use a tablet and fitness tracker daily for about an hour before their surgery.
Boston, MassachusettsAges 60 years+ - NCT06727370Recruiting
Cognitive screening for lung cancer patients
This study is testing a simple thinking and memory check for people with lung cancer. The goal is to find out how common cognitive problems are and to help doctors better support patients.
MilanAges 18–70 - NCT06730074Recruiting
Robotic exercise for Parkinson's motor and thinking skills
This study tests a new robotic system that combines movement and mental exercises for people with Parkinson's. It may help improve both your physical and thinking skills.
Ofakim, SouthAges 50–75 - NCT06730711Recruiting
Blood pressure and stroke-related thinking changes
This study looks at how blood pressure after a stroke might affect your thinking and memory. It uses information from your hospital stay and follow-up visits to see if there is a link.
Chongqing, Chongqing MunicipalityAges 18–90 - NCT06731452Recruiting
Brain health study with MRI and TMS
This study looks at brain activity patterns in healthy adults. You'll have an MRI and a non-invasive brain stimulation session (TMS) to help researchers understand how the brain works. If you're already in The BrainHealth Project, this is a chance to learn more about your own brain health.
Dallas, TexasAges 22–100 - NCT06733376Recruiting
PTSD treatment options study
This study tests different types of talk therapy for PTSD, like CPT, PE, and STAIR. It aims to find which treatment works best for people with PTSD.
Chicago, IllinoisAges 18 years+ - NCT06735599Recruiting
Wild blueberries for blood pressure health
This study tests whether eating wild blueberries can improve your gut, brain, and heart health if you have high blood pressure. You'll eat blueberries daily for several weeks and have checkups to see how your body responds.
Atlanta, GeorgiaAges 45–65 - NCT06735651Recruiting
Wild blueberries for gut, brain, and heart health in prediabetes
This study looks at whether eating wild blueberries can improve your gut health, brain function, and heart health if you have prediabetes. It may help lower your blood sugar and reduce your risk for diabetes and heart disease.
Atlanta, GeorgiaAges 20–65
Hear when a new Cognitive trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for cognitive?
- Yes. Clin2 currently lists 2,028 recruiting cognitive studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cognitive trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cognitive trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.