Clinical trials
Cognitive clinical trials
Below are recruiting cognitive clinical trials, each written for real people, not researchers. We’re tracking 1,981 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06733376Recruiting
PTSD treatment options study
This study tests different types of talk therapy for PTSD, like CPT, PE, and STAIR. It aims to find which treatment works best for people with PTSD.
Chicago, IllinoisAges 18 years+ - NCT06721819RecruitingPhase 3
Sleep and brain training before heart surgery to prevent delirium
This study tests whether a combination of sleep therapy, brain games, and light exercise before heart surgery can help prevent confusion or disorientation (delirium) after the operation. Participants will be asked to use a tablet and fitness tracker daily for about an hour before their surgery.
Boston, MassachusettsAges 60 years+ - NCT06721559Recruiting
Home program for older adults with depression and mobility issues
This study tests a home-based program called Empower@Home for older adults who have depression and trouble moving around. It aims to see if the program helps improve mood and daily life—without adding extra outside therapy.
Ann Arbor, MichiganAges 50 years+ - NCT06722976Enrolling by invitation
Digital health and exercise for staying independent longer
This trial tests a program that combines digital health tools with exercise to help older adults stay active and independent. It may be a good fit if you are 65 or older and can walk or move around without major difficulty.
Covilha, CovilhãAges 60 years+ - NCT06725953Recruiting
Remote exercise program for cancer survivors with or without diabetes
This study tests a 12-week home-based physical activity program to see if it helps cancer survivors who had chemotherapy and now have memory or thinking problems. It includes both survivors with type 2 diabetes and those without.
Oklahoma City, OklahomaAges 18 years+ - NCT06723015Enrolling by invitationPhase 2
Tau PET in anti-amyloid therapy for Alzheimer's
This study uses brain scans to see how anti-amyloid treatments affect tau protein buildup in people with early Alzheimer's. If you have mild cognitive impairment or mild Alzheimer's, you may be eligible to help understand how these treatments work.
Rochester, MinnesotaAges 50–90 - NCT06705816Recruiting
Cognitive function in Rett syndrome during trofinetide treatment
This study looks at how trofinetide (a medicine for Rett syndrome) affects thinking and memory in people with Rett syndrome. It will follow participants who are starting this treatment through a specific clinic.
Minneapolis, MinnesotaAges 18–99 - NCT06710418Recruiting
Comparing two red blood cell transfusion thresholds for people with high-grade myeloid neoplasms, AML or B-ALL
This study compares two different strategies for when to give red blood cell transfusions to people receiving intensive chemotherapy or stem cell transplant for high-grade myeloid neoplasms, AML or B-ALL. The goal is to see which approach better improves quality of life and daily function.
Seattle, WashingtonAges 18 years+ - NCT06709027Enrolling by invitation
Mobile health program for depression in older adults
This study is testing a smartphone-based health program designed for older adults with depression. The program aims to help you manage your mood and track changes in thinking and memory using a mobile app.
Fuzhou, FujianAges 60 years+ - NCT04903015Recruiting
Study brain effects in retiring pro soccer players
This study looks at how years of playing professional soccer may affect the brain and thinking, using MRI (brain scans) and comparisons to people who had little head-impact sports exposure. You might join if you are a retiring Ligue 1 or Ligue 2 player and meet the injury and health criteria.
StrasbourgAges 32–55 - NCT06695910RecruitingPhase 4
Testing an omega-3 supplement for brain fog
This trial tests whether a special form of omega-3 (MAG-EPA) can help people with ongoing brain fog symptoms like mental fatigue, memory loss, or trouble concentrating. If you've had these issues for at least 28 days, you may be eligible.
Maria, QuebecAges 19–55 - NCT06697418Enrolling by invitation
Physical activity and heart health in peritoneal dialysis patients
This study uses a wrist-worn device to see how daily physical activity affects heart health and other outcomes for people on peritoneal dialysis. If you are on PD, can walk on your own, and are willing to wear a tracker, you may be able to join.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06703541Recruiting
Alzheimer's disease research study with brain scans and spinal tap
This study at Duke University is looking for people aged 25 to 80 who may be at risk for Alzheimer's disease. It involves brain scans (MRI and PET) and a spinal tap to learn more about the disease and find better ways to detect and treat it early.
Durham, North CarolinaAges 25–80 - NCT06700187Recruiting
Does reducing sitting time improve thinking?
This study looks at whether taking short breaks from sitting can help your brain work better. You will visit a lab 4 times and will be asked to sit or take short breaks while your thinking is tested.
MaastrichtAges 18–35 - NCT06694441Recruiting
Sleep, brain chemicals, and memory in older adults with insomnia
This study looks at how a brain chemical called norepinephrine affects sleep and thinking in older adults with insomnia. You may join if you are 55+, have insomnia, and are generally healthy.
Chicago, IllinoisAges 55 years+ - NCT06695806Enrolling by invitation
Uncertainty in osteopaths study
This study measures how osteopaths handle uncertainty. It looks at students and graduates to understand their tolerance for uncertain situations.
Saint-HerblainAges 18–60 - NCT06332560Recruiting
Endometriosis pain and lifestyle
This study looks at how diet and lifestyle changes, including cognitive behavioral therapy (a type of talk therapy), might help reduce pain from endometriosis. You would follow a special diet and attend therapy sessions while researchers track your symptoms.
's-HertogenboschAges 17 years+ - NCT06689878Recruiting
Mobile therapy for anxiety and depression after stroke
This study tests if a mobile cognitive behavioral therapy app can help reduce anxiety and depression in people who have had a stroke. If you are between 40 and 79 and have ongoing feelings of worry or low mood after your stroke, this therapy might be a convenient option.
New York, New YorkAges 40–79 - NCT06691698Recruiting
CO-OP therapy for teens with mild intellectual disability
This study tests a therapy called CO-OP, which helps teens with mild intellectual disability learn skills to reach their own goals. You'll work with a therapist once a week for 10 weeks, with a parent or adult to support you.
Kristianstad, Skåne CountyAges 13–17 - NCT06684444Enrolling by invitationPhase 4
Sleep coaching study for firefighters with sleep troubles
This study tests if health coaching can help career firefighters sleep better. You'll have private coaching sessions by phone or computer.
Tucson, ArizonaAges 18 years+ - NCT06687044Enrolling by invitation
Sleep therapy for better pregnancy outcomes
This study tests whether a sleep improvement therapy can help pregnant women (with one or two babies) by improving their sleep and pregnancy outcomes. It's for women who are early in their pregnancy and having sleep problems but are otherwise healthy.
Shenyang, LiaoningAges 18–45 - NCT06687291Recruiting
Thinking and memory after stomach or esophagus cancer surgery
This study looks at how surgery and chemotherapy for stomach or esophageal cancer may affect your thinking, memory, and other cognitive functions. Researchers want to understand these changes to better support patients.
HuddingeAges 18 years+ - NCT05982730Recruiting
Segway training for balance and thinking in Parkinson's
This study tests whether practicing balance on a Segway can improve walking and thinking for people with moderate Parkinson's. You will train on a Segway while getting special sensory cues, and researchers will see if it helps your motor skills and cognitive function.
Dallas, TexasAges 50–85 - NCT06592352RecruitingPhase 2
Modafinil for thinking problems in MS
This study tests whether the medication modafinil can improve thinking and memory problems in people with MS. If you have MS and notice cognitive changes like forgetfulness or trouble focusing, you may be eligible.
BragaAges 18–64
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Common questions
- Are there clinical trials for cognitive?
- Yes. Clin2 currently lists 1,981 recruiting cognitive studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cognitive trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cognitive trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.