Clinical trials
Cognitive clinical trials
Below are recruiting cognitive clinical trials, each written for real people, not researchers. We’re tracking 2,028 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06010511Recruiting
White matter changes and brain fluid study in older adults
This study uses special MRI scans to look at white matter changes in the brain (often linked to memory problems). It may help doctors understand more about these changes in older adults visiting memory or geriatric clinics.
LeidenAges 65 years+ - NCT06032377Recruiting
Online therapy for sleep and brain health in older adults
This study tests an online talk therapy program (CBT) to help older adults with both sleep troubles and mild memory or thinking concerns. It's done from home, and aims to improve sleep and brain health.
Ottawa, OntarioAges 60–99 - NCT06051240RecruitingPhase 2
Lithium to prevent thinking problems after brain radiation
This study tests if the drug lithium can help prevent memory and thinking problems that sometimes happen after brain radiation for a brain tumor. You may qualify if you are under 18 when treated and had radiation within the last 7 years.
Solna, Stockholm CountyAges 5 years+ - NCT06060860Recruiting
Comparing two therapies for autistic adults with depression or anxiety
This study compares two types of talk therapy — cognitive-behavioral therapy (CBT) and mindfulness-based therapy — to see which works better for autistic adults who also have depression or anxiety. You would attend online sessions from home.
Chapel Hill, North CarolinaAges 18 years+ - NCT06095063Recruiting
Magnetic brain stimulation for memory concerns with family Alzheimer's history
This study tests whether a type of magnetic brain stimulation (dTMS) can help people who are worried about their memory. It is for people who have a family history of Alzheimer's but are still thinking clearly.
Toronto, OntarioAges 55–70 - NCT06095297Recruiting
Cognitive rehab for brain fog from long COVID
This study tests a computer-based cognitive training program combined with a gentle nerve stimulation device to see if it can improve brain fog and daily functioning in people with long COVID. If you're struggling with thinking, memory, or concentration after COVID, this might help.
Birmingham, AlabamaAges 18 years+ - NCT06150352Recruiting
Sleep apnea and memory in older adults with mild concerns
This trial looks at how sleep apnea affects memory and brain health in people who have mild memory problems or are worried about their memory. You will have a sleep study and brain scans to see if treating sleep apnea could help protect your thinking skills.
Hong KongAges 50–80 - NCT06223672Recruiting
Healthy fats for better thinking in older adults
This study tests whether healthy fats can help improve thinking and memory in people with mild memory concerns. It is for people with overweight and normal blood sugar.
Columbus, OhioAges 40–75 - NCT06238492Recruiting
Boosting brain speed after spinal cord injury
This trial tests a program to help improve how quickly your brain processes information after a recent spinal cord injury. It focuses on people who are about 6 months post-injury.
Englewood, ColoradoAges 18–59 - NCT06248723Recruiting
Preventing memory decline in older adults with lifestyle changes
This study tests a personalized program of lifestyle changes (diet, exercise, brain training, etc.) to see if it can prevent memory loss and keep older adults independent. You may qualify if you are 60+, have mild frailty, and have certain risk factors for dementia.
MonzaAges 60 years+ - NCT06268080Recruiting
Sedation depth and mental recovery after surgery for older adults
This trial tests whether monitoring how deeply you sleep during anesthesia helps prevent confusion and memory problems after surgery. It is for older adults who can give consent and are having a major operation.
Grafton, AucklandAges 55 years+ - NCT06286202Recruiting
Cognitive skills program for schizophrenia recovery
This trial tests a community-based program called INSPIRE that uses mental exercises and social coaching to help people with schizophrenia or schizoaffective disorder improve their thinking skills and daily functioning. It is conducted in English and requires at least 10 years of English-language education.
SingaporeAges 21–60 - NCT07639203Recruiting
Brain training app for healthy aging
This trial tests a digital brain-training program designed to improve thinking skills like planning and memory in healthy older adults. It may help you stay sharp as you age.
Rovereto, TrentoAges 65–75 - NCT06335836Recruiting
Social connections and brain health in memory decline
This study looks at how being socially isolated or socially active affects memory and brain health in people who feel their thinking is getting worse. You may join if you notice a slow decline in memory or thinking, but otherwise have normal test results.
Nanjing, China, JiangsuAges 45–85 - NCT06346535Recruiting
PrimeCog: New thinking tests for recent depression or stress diagnosis
This trial studies new digital tests that could help doctors in primary care detect cognitive (thinking) problems in people recently diagnosed with depression or stress-related disorders. The goal is to find reliable early signs of cognitive changes so treatment can be better tailored.
Linköping, Östergötland CountyAges 18–65 - NCT06347315Recruiting
Studying a nutritional drink for mild memory loss in older adults
This study tests whether a special drink containing medium-chain triglycerides (MCTs, a type of fat) and B vitamins can help support memory and thinking in older adults with mild cognitive impairment (MCI). You would take the drink daily for 18 months and have regular check-ins including memory tests.
BronAges 60 years+ - NCT06392945Recruiting
Walking and thinking training with music for chronic stroke recovery
This trial tests whether adding a rhythmic beat (like a metronome or music) to walking while doing thinking tasks can improve walking after a stroke. It is for people who had a stroke more than 6 months ago and can already walk a short distance.
TaipeiAges 20–85 - NCT06408103Recruiting
Brain health program for you and your caregiver
This study tests a program that combines exercise, nutrition, and mental activities for both you and your family caregiver. It aims to help keep your thinking and memory skills strong.
Bucaramanga, Santander DepartmentAges 55 years+ - NCT06411561Recruiting
Boosting memory after ICU stay for older adults
This study tests a combination of activities (like cognitive training and exercise) to help older adults recover thinking and memory after a serious illness in the ICU. It may help you regain sharpness and independence after leaving the intensive care unit.
Seattle, WashingtonAges 60 years+ - NCT06413173Recruiting
Remote brain stimulation for attention after mild TBI
This trial tests if a remote brain stimulation device can improve attention and concentration in active-duty service members who have had a mild traumatic brain injury. Participants use the device at home while completing tasks to help with daily focus.
San Diego, CaliforniaAges 18–60 - NCT06442943Recruiting
Digital brain training for people at risk of dementia
This trial tests a digital program designed to improve memory and thinking skills in people who are at high risk for dementia but do not yet have dementia.
Fuzhou, FujianAges 55 years+ - NCT06448403Recruiting
Alzheimer's assessment study with brain scans
This study uses brain scans (MRI and EEG) to better understand Alzheimer's disease. It compares people with MCI or Alzheimer's to healthy volunteers to see how the disease affects the brain.
Trondheim, TrønderlagAges 65 years+ - NCT06467253Recruiting
Brain stimulation plus memory training for mild memory loss
This study tests two gentle brain stimulation methods combined with memory training for people with mild memory loss. It aims to help improve thinking and memory skills over 8 weeks at a psychiatric hospital in Mexico City.
Mexico CityAges 55–85 - NCT06507254Recruiting
Polyphenols and brain health in aging
This study tests whether eating more polyphenols (natural compounds in plants) can protect brain health in people at higher risk for Alzheimer's disease, especially if they currently eat a typical Western diet. Participants will be followed over time to see if changes in diet affect thinking and memory.
Los Angeles, CaliforniaAges 50 years+
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Common questions
- Are there clinical trials for cognitive?
- Yes. Clin2 currently lists 2,028 recruiting cognitive studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cognitive trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cognitive trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.