Clinical trials
Coronary artery disease clinical trials
Narrowing of the arteries that supply blood to the heart. We’re tracking 712 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06451198RecruitingPhase 4
Indobufen vs aspirin after stent in older heart patients
This trial tests whether a blood thinner called indobufen works as well as aspirin for older people (65+) who have had a heart attack or unstable angina, received a drug-eluting stent, and are already taking two blood thinners. The goal is to find a safer or better option for long-term prevention.
Shanghai, Shanghai MunicipalityAges 65 years+ - NCT06434935Enrolling by invitationEarly Phase 1
Trial of a new bypass graft for heart surgery
This trial tests a new artificial blood vessel for heart bypass surgery. If you need a bypass and meet the health requirements, you may be able to receive this experimental graft.
AsunciónAges 45–75 - NCT05732701Recruiting
Personalized blood thinner plan after stent placement
This trial tests an algorithm (computer-guided plan) to choose the best “dual antiplatelet therapy” (two blood-thinning medicines) after a coronary stent. It aims to improve outcomes after the procedure while reducing avoidable problems from the medicines.
Banja LukaAges 18 years+ - NCT06399692RecruitingPhase 3
Choosing heart bypass or stents for women with heart disease
This study compares two common procedures to improve blood flow to the heart in women with blockages in multiple heart arteries. It aims to find which approach works better for women and may help guide future treatment decisions.
Glendale, CaliforniaAges 18 years+ - NCT06399705RecruitingPhase 3
Comparing bypass surgery versus stenting for Black and Hispanic patients with coronary artery disease
This study compares two common ways to treat blocked heart arteries: bypass surgery and stenting. It aims to find which works better for Black and Hispanic patients with multiple blockages.
Glendale, CaliforniaAges 18 years+ - NCT06410690Recruiting
AI tool to predict high-risk coronary plaques from heart scans
This trial uses an artificial intelligence (AI) tool to analyze heart CT scans (CCTA) and identify dangerous plaque buildup that could lead to a heart attack. It aims to see if AI can better predict high-risk plaques in people with known or suspected coronary artery disease (CAD).
Milan, MilanAges 18 years+ - NCT06374498Enrolling by invitation
Looking inside heart arteries to improve stent placement
This study tests a new imaging technique to help doctors see inside your heart arteries during a stent procedure. It may help guide treatment and improve outcomes for people with heart disease.
Boston, MassachusettsAges 18 years+ - NCT06373601Recruiting
Testing a drug-coated balloon for small heart arteries
This study tests a drug-coated balloon (DCB) that releases two medicines (sirolimus and paclitaxel) to open blocked small heart arteries. It may help people with stable chest pain or recent, controlled heart events who have a narrowed small vessel.
Mercogliano, Italy/AvellinoAges 18 years+ - NCT06369142Recruiting
Shockwave lithotripsy for severe calcium in heart arteries
This study tests a new method called coronary lithotripsy to break up severe calcium deposits in heart arteries before placing a stent. It may help people with very hard, calcified blockages that are hard to treat with standard stenting.
Heidelberg, Baden-WurttembergAges 18 years+ - NCT06327984Recruiting
Sex hormones and inflammation in heart disease
This study looks at how sex hormones and inflammation affect chest pain and heart disease. It aims to improve care for people with coronary artery disease.
LondonAges 16 years+ - NCT06326996RecruitingEarly Phase 1
Thiamine before bypass surgery
This study tests if giving thiamine (vitamin B1) before heart bypass surgery can help people with low thiamine levels. It is designed for patients who are having a specific type of bypass that does not use a heart-lung machine.
Los Angeles, CaliforniaAges 60–80 - NCT06314295Recruiting
AI heart ultrasound to find blocked arteries
This trial uses artificial intelligence to analyze heart ultrasound images and detect blocked arteries in people with suspected coronary artery disease. It aims to see if AI can accurately find problems without needing more invasive tests.
BeijingAges 18–90 - NCT06275386Recruiting
Drug-coated balloon for chronic heart artery blockages
This trial tests whether a special balloon coated with medicine (drug-coated balloon) can safely open a completely blocked heart artery, instead of using a permanent stent. It may be an option for people who have chronic chest pain or shortness of breath due to a long-standing blockage.
Warsaw, Masovian VoivodeshipAges 18 years+ - NCT06259019Recruiting
Blood test during heart procedure to find disease markers
This trial uses a special device to take a small blood sample from your heart arteries during a planned procedure. It aims to find unique markers that could help doctors better understand and treat coronary artery disease.
BournemouthAges 18 years+ - NCT06235112Recruiting
AI Screening for Heart Calcium from Chest CT Scans
This research study uses an artificial intelligence program to screen old chest CT scans for calcium buildup in the heart arteries. If you are between 40 and 75 and have had a chest CT in the last 3 years, this may help identify if you are at risk for heart disease so you can take steps to prevent it.
Boston, MassachusettsAges 40–75 - NCT06228456RecruitingPhase 4
Low-dose ticagrelor vs clopidogrel for stable heart patients after stent
This trial tests whether a lower dose of the blood thinner ticagrelor works better than clopidogrel in people with stable coronary artery disease who are getting a planned stent. It aims to find which drug is safer and more effective for preventing future heart problems.
Jacksonville, FloridaAges 18 years+ - NCT06182683Recruiting
OCT-Guided vs. FFR-Guided Stent Placement in Heart Disease
This trial compares two imaging and pressure tests used during stent placement to see which helps improve blood flow better in people with chest pain or a recent heart attack.
SeoulAges 19 years+ - NCT06185530Recruiting
Comparing stress echo vs CT scan for chest pain
This trial compares two heart imaging tests (stress echo with ultrasound of the neck, and a CT scan) to see which one better helps guide treatment for people with chest pain that might be from heart disease. If you have chest pain that is typical for heart disease, you may be able to join.
Harrow, MiddxAges 18 years+ - NCT06168305Enrolling by invitation
Safety and effectiveness of a GENOSS stent in multiple blocked arteries
This trial tests a new drug-coated stent (GENOSS® DES) for people with blockages in multiple heart arteries. It aims to see how safe and effective the stent is for these patients.
Seoul, SeoulAges 19 years+ - NCT06164730RecruitingPhase 1
Study of VERVE-102 for high cholesterol or early heart disease
This trial tests a new medicine called VERVE-102 for people with a specific type of high cholesterol (HeFH) or early coronary artery disease. It aims to see if it can help lower cholesterol levels.
Dothan, AlabamaAges 18–70 - NCT06164457Recruiting
Using patient reports to improve heart disease care
This trial tests whether asking patients to report their own symptoms and quality of life during routine heart check-ups helps doctors better care for people with coronary artery disease. You may be eligible if you are 40 or older, have known or suspected heart artery problems, and have an upcoming visit with a cardiologist.
Calgary, AlbertaAges 40 years+ - NCT06177743Recruiting
Coroflex NEO heart stent study
This study monitors patients who receive a Coroflex ISAR NEO stent to track how well it works over time. It helps doctors understand the safety and effectiveness of this specific stent.
Seoul, Songpa-guAges 19 years+ - NCT06143332Recruiting
Aerobic exercise after a heart attack: which type works best?
This study compares two types of aerobic exercise (steady vs. interval) to see which one improves heart health more for people who have recently had a heart attack or procedure. If you've completed a stress test and been cleared for exercise, you may be able to join.
London, OntarioAges 18 years+ - NCT06137521Recruiting
Heart artery blockage study
This study looks at people with a long-standing complete blockage in a heart artery. The goal is to understand risk factors and outcomes, which may help guide future treatments.
ShanghaiAges 18 years+
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Common questions
- Are there clinical trials for coronary artery disease?
- Yes. Clin2 currently lists 712 recruiting coronary artery disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a coronary artery disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a coronary artery disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.