Clinical trials
Coronary artery disease clinical trials
Narrowing of the arteries that supply blood to the heart. We’re tracking 731 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05933720Recruiting
Study drug peptides for blocked leg artery disease
This study tests how well a drug called Slavinorm® (regulatory polypeptides) works and is safe for adults with blocked arteries in the legs due to atherosclerosis. You might be considered if you have confirmed leg artery blockage and can safely do a treadmill walking test.
RyazanAges 18–80 - NCT06170541Recruiting
Comparing heart artery scans for coronary disease
This study tests whether a newer CT scan method can better detect coronary heart disease. You may qualify if your doctor referred you for a heart CT scan.
Baltimore, MarylandAges 21–85 - NCT07165678Recruiting
CT Scan Before Heart Catheterization After Bypass Surgery
This study tests whether having a CT scan of the heart before a standard heart catheterization is helpful for people who have had bypass surgery. It could reduce risks and improve planning.
LondonAges 18 years+ - NCT07451873Recruiting
Glycocalyx and stress in blood vessel function (Part 2)
This study looks at how a protective layer inside your blood vessels (the glycocalyx) and oxidative stress affect blood vessel function after heart bypass surgery. The goal is to better understand why some people recover differently.
OsijekAges 18 years+ - NCT07514611Recruiting
Weight Loss Guidance for Heart Disease and Obesity
This trial tests whether using a smartphone app to guide weight loss helps people with coronary heart disease (a condition where blood vessels to the heart are narrowed) and obesity lose weight safely. The goal is to see if this personalized digital guidance can improve your health outcomes.
Guangzhou, GuangdongAges 18–65 - NCT06795763Enrolling by invitation
New imaging & catheter system for blocked heart arteries
This trial tests a new imaging and catheter system to treat chronic total blockages in heart arteries. If you still have chest pain or other symptoms despite medical therapy, this study may help open the blockage and improve blood flow.
Atlanta, GeorgiaAges 18 years+ - NCT05257629RecruitingPhase 3
Aggressive smoking quit program after heart problems
This trial tests whether a strong quit plan using varenicline (a quit pill) plus nicotine e-cigarettes, along with counseling, helps people stop smoking after a recent heart-related event. It’s aimed at people who want to quit and can safely stay involved for about a year.
New Westminster, British ColumbiaAges 18 years+ - NCT01730092Recruiting
Study of blood and imaging biomarkers in pulmonary artery hypertension
This study tracks natural changes in “biomarkers” (measurable signals in blood) and imaging findings in people with pulmonary arterial hypertension (PAH) or suspected PAH. It also includes healthy people for comparison, helping researchers understand what these signals mean over time.
Bethesda, MarylandAges 18–100 - NCT07175038RecruitingPhase 2
Study of a new pill for pulmonary hypertension
This study tests a new pill, ROC-101, for people with pulmonary hypertension (high blood pressure in the lungs). It aims to see if the pill can improve symptoms and daily function.
Phoenix, ArizonaAges 18–80 - NCT05476991RecruitingPhase 3
Low-dose colchicine plus ticagrelor to prevent repeat stroke
This Phase 3 study tests whether low-dose colchicine added to ticagrelor (a blood-thinning medicine) helps prevent another ischemic stroke in people whose first stroke was caused by clogged arteries. It aims to lower the risk of repeat stroke after recovery from a recent event.
Paris, ParisAges 18 years+ - NCT07270718Recruiting
Beetroot powder for blood pressure in men with hypertension
This trial tests whether taking 20 grams of beetroot powder daily can help lower blood pressure and improve blood flow in men who already have high blood pressure under control with medication. Beetroot is rich in nitrates, which may relax blood vessels.
MoscowAges 18–60 - NCT05444452Recruiting
Stent treatment study for blocked heart arteries
This study tests a coronary stent approach for people with significantly blocked heart arteries. It may help by improving blood flow, and it compares treatment in a structured way while monitoring safety and outcomes.
SeoulAges 19 years+ - NCT05727852Enrolling by invitation
Breath and heart tests to study lung disease stiffness
This study uses breath analysis and heart/electrical heart testing to look at how stiff the arteries are in people with long-term lung conditions. It may help researchers better understand lung disease effects on the cardiovascular system.
MoscowAges 18 years+ - NCT05790603Recruiting
Patent hemostatic device after wrist procedures with pressure
This trial tests whether a specific wrist compression device with measured pressure works better for stopping bleeding after a heart catheter procedure done through the radial artery (wrist). It may help reduce complications like prolonged bleeding once the procedure is finished.
Beijing, Beijing MunicipalityAges 18–80 - NCT07245680RecruitingPhase 3
Testing two pills vs one for pulmonary hypertension with heart or metabolism issues
This trial compares starting with two oral medications versus one for people newly diagnosed with pulmonary arterial hypertension (PAH) who also have conditions like high blood pressure, diabetes, obesity, or heart disease. The goal is to see if a two-drug approach works better for patients with these additional health issues.
Le Kremlin-BicêtreAges 18 years+ - NCT07620925Recruiting
Aortic Valve Calcium Score Study Using Heart Ultrasound
This study develops and tests a new way to diagnose severe aortic stenosis (narrowing of the aortic valve) by measuring calcium buildup on the valve using heart ultrasound. If you're already getting both an ultrasound and a CT scan of your heart, this study compares how well the ultrasound method can identify severe stenosis.
BolognaAges 18 years+ - NCT06663696Recruiting
A study of Supraflex Cruz stents for multivessel heart disease
This trial is monitoring patients who receive Supraflex Cruz stents in multiple blocked heart arteries. It aims to gather real-world safety and effectiveness data to help improve future care.
SousseAges 18–99 - NCT05812963Recruiting
IVUS vs FFR to guide stents after heart attacks
This trial compares two ways of measuring blood flow inside the heart arteries (IVUS vs FFR) to help decide which non–culprit artery narrowings need a stent after a recent heart attack. It may help doctors choose the best targets for PCI and avoid unnecessary procedures.
GwangjuAges 19 years+ - NCT06443151Recruiting
Blood Vessel Health After Spinal Cord Injury
This study looks at how blood vessel health is affected in people with long-term spinal cord injury (over 1 year). It tests whether blood vessel function plays a role in heart and circulatory risk.
Englewood, ColoradoAges 18–89 - NCT06506448Recruiting
Studying non-blocked arteries after a heart attack
This study looks at arteries in the heart that aren't the one that caused the heart attack. It uses a special CT scan to understand these arteries better in people who have already had a procedure to open the blocked artery.
Bournemouth, DorsetAges 18–85 - NCT07293260RecruitingPhase 3
Olpasiran heart scan study for high Lp(a) patients
This study tests if a medication called olpasiran can lower a type of fat in your blood called Lp(a), which is linked to heart problems. You take the medicine or a placebo and get a special heart scan to see changes in your arteries.
Bridgeport, ConnecticutAges 35–80 - NCT06676280RecruitingPhase 4
Aspirin and statin study for high coronary calcium
This trial tests whether a daily aspirin and a statin medicine can help prevent heart problems in people with high calcium buildup in their heart arteries. It is for people aged 40 to 75 who have a high coronary calcium score (300 or more) and at least one additional risk factor like diabetes or high blood pressure.
AnyangAges 40–75 - NCT06091319Recruiting
Florbetaben imaging for vascular amyloid after heart or brain event
This trial tests whether florbetaben, a special dye, can show amyloid buildup in blood vessels after a recent heart attack, chest pain episode, or stroke. It aims to help doctors better understand and prevent future events.
Ottawa, OntarioAges 18 years+ - NCT05859022Recruiting
Bariatric treatment methods compared for diabetes and metabolism
This trial compares a less invasive heart/artery-based bariatric treatment (bariatric arterial embolization) with standard weight-loss surgery to see how they affect metabolism and type 2 diabetes. You might be considered if you have obesity with type 2 diabetes and have not had prior bariatric surgery.
LisbonAges 18–75
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Common questions
- Are there clinical trials for coronary artery disease?
- Yes. Clin2 currently lists 731 recruiting coronary artery disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a coronary artery disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a coronary artery disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.