Clinical trials
Couples clinical trials
Below are recruiting couples clinical trials, each written for real people, not researchers. We’re tracking 97 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06783283Recruiting
Brain stimulation to improve memory in mild cognitive impairment
This trial tests whether a gentle electrical brain stimulation technique called tACS can improve working memory in people with mild cognitive impairment (MCI). If you have MCI due to early Alzheimer's, this study may help find new ways to boost memory.
Toronto, OntarioAges 60 years+ - NCT06865872Recruiting
Alcohol and couple communication study
This study looks at how alcohol affects communication between partners in a relationship. You'll be asked to drink a small amount of alcohol and then discuss topics with your partner in a lab setting.
Aurora, ColoradoAges 21–65 - NCT06875414Recruiting
Breast cancer and couple resilience study
This study looks at how couples handle a breast cancer diagnosis and treatment together. Researchers want to understand how the relationship affects coping and well-being.
Roma, RomeAges 18 years+ - NCT06887140Recruiting
Heart-lung function test in sepsis patients
This study uses an ultrasound of the heart (echocardiogram) to check how well the right side of your heart is working with your lungs during sepsis. The goal is to see if this measurement can help doctors predict how patients will recover.
Ho Chi Minh CityAges 18 years+ - NCT06911671Recruiting
VR and brain stimulation for arm recovery after stroke
This study tests a combination of virtual reality therapy and brain stimulation to help people recover arm movement after a stroke. It uses a special interface controlled by muscle signals and applies stimulation to the cerebellum to improve motor control.
Roma, RomeAges 18–80 - NCT06952777Recruiting
Testing sensors to monitor babies in the womb
This study tests new sensors to check on a baby's wellbeing during the third trimester of pregnancy, as an alternative to standard monitors. You would wear a sensor on your belly to track your baby's heartbeat and movements without wires or needles.
ManchesterAges 16–50 - NCT06956287Recruiting
New sperm-wash device for infertility couples
This trial tests a new device that cleans sperm before it's used in intrauterine insemination (IUI), a common fertility treatment. It aims to see if this device improves sperm quality and pregnancy chances for couples struggling with infertility.
Taichung, Taichung CityAges 25–50 - NCT07029126Recruiting
Fremanezumab for migraine with depression: caregiver impact study
This trial tests if fremanezumab, a migraine prevention drug, can also reduce the stress and improve the relationship between migraine patients with mild depression and their caregivers. If you or someone you care for has migraines and low mood, this study may help understand how the caregiver is affected.
Rome, ItalyAges 18 years+ - NCT07052344Recruiting
Brain-gut connection study in spinal cord injury
This study looks at how the brain and gut communicate in people with spinal cord injury (SCI) and healthy controls. It uses non-invasive methods to understand these signals, which might help improve bowel and overall health.
Miami, FloridaAges 18–70 - NCT07073781Recruiting
Probiotics for Brain & Blood Sugar in Overweight Young Adults
This study tests whether taking a probiotic (a 'good bacteria' supplement) can help brain function (thinking, memory) and improve blood sugar control in overweight adults who have higher-than-normal blood sugar. If you're between 18-40, overweight, and don't have diabetes, you may be able to join.
Leeds, Greater ManchesterAges 18–40 - NCT07142512Recruiting
Can talking with your partner help you walk more with diabetes?
This study looks at whether helping couples communicate better can help people with type 2 diabetes walk more. You and your partner will be asked to have a conversation that is video recorded, and you will get a step goal to work toward.
Montreal, QuebecAges 45 years+ - NCT07329647Recruiting
Brain nutrition study for cognitive decline
This trial tests whether a nitrate-rich food supplement can improve blood flow in the brain and help thinking and memory. It is for people with small vessel disease in the brain or diabetes who are at risk for cognitive decline.
CoimbraAges 18 years+ - NCT07374276Recruiting
Brain-computer interface with virtual reality for stroke recovery
This trial tests if combining a brain-computer interface (a device that reads brain signals) with virtual reality (an immersive computer environment) can help improve arm movement after a stroke. It might be a good fit if you had a stroke 6 to 24 months ago and still have some weakness in one arm.
Alcabideche, Lisbon DistrictAges 18–80 - NCT02596490Recruiting
Couple meditation program for metastatic lung cancer and partners
This study tests whether a couple-based meditation program can help people with stage IV non-small cell lung cancer and their romantic partners cope better during treatment. It looks at the experience of both the patient and their partner, not just the patient alone.
Houston, TexasAges 18 years+ - NCT07483515Recruiting
Bonding before birth: an app for first-time parents
This trial tests a mobile health app for first-time expectant couples to strengthen bonding during pregnancy. It may help reduce stress and improve emotional connection.
SingaporeAges 21–75 - NCT07433582Recruiting
Mindfulness training for couples in Dutch
This trial tests whether a mindfulness program designed for couples can improve your relationship. You and your partner will attend sessions together to learn mindful communication skills.
Nijmegen, GelderlandAges 20 years+ - NCT07532629Recruiting
How Gut Bacteria Affect IVF Success in Couples
This study examines how the bacteria in your gut and your partner's gut may affect the success of IVF (in vitro fertilization) treatment. Researchers will collect samples and health information from couples before IVF to see if certain bacterial patterns predict better pregnancy outcomes.
MalmöAges 18–40 - NCT07537621Recruiting
How the heart's right chamber responds to fluids in ICU
This study watches how the right side of your heart responds when doctors give you extra fluids to improve blood flow during a critical illness. Understanding this response may help doctors make better decisions about fluid treatment in the ICU.
ReimsAges 18 years+ - NCT07553962Recruiting
How couples support each other when quitting smoking
This study looks at how couples who both smoke can help each other quit. Researchers want to understand the ways partners support one another during a smoking cessation attempt, which may help improve quit success rates.
Denver, ColoradoAges 18 years+ - NCT07601867Recruiting
Dapagliflozin to improve heart function after bypass surgery
This trial tests whether a diabetes medication called dapagliflozin can help improve how well the right side of your heart works after off-pump coronary artery bypass grafting surgery (a way to reroute blood around blocked heart arteries). The goal is to see if this drug reduces strain on your heart during recovery.
Pyatigorsk, Stavropol KrayAges 18 years+ - NCT07664579Recruiting
Couples coping together against cancer support program
This trial tests a supportive care program for couples facing cancer. It helps you and your partner work together to manage the challenges of a cancer diagnosis.
Duarte, CaliforniaAges 18 years+ - NCT07669584RecruitingPhase 2/Phase 3
Testing PKB171 for mild male infertility in couples
This study tests a new oral medication (PKB171) compared to a placebo for couples who have mild male infertility and have not tried IVF/ICSI before. The goal is to see if PKB171 can help them conceive naturally.
Pamplona, NavarreAges 18–38 - NCT07285434Enrolling by invitationEarly Phase 1
Personalized vaccine for first-line advanced lung cancer
This study tests a personalized vaccine (Microlyvaq™) made just for your tumor, given together with standard chemo and immunotherapy (pembrolizumab). It is for people with advanced non-small cell lung cancer who have not yet started treatment for the advanced stage.
Thessaloniki, MacedoniaAges Any age - NCT07100223Enrolling by invitation
Parenting and birth preparation class for couples
This study offers couples a class on parenting and getting ready for birth. It may help you feel more prepared and connected during your first pregnancy.
Kayseri, Kocasi̇nanAges 18–35
Hear when a new Couples trial opens
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Common questions
- Are there clinical trials for couples?
- Yes. Clin2 currently lists 97 recruiting couples studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a couples trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a couples trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.