Clinical trials
Couples clinical trials
Below are recruiting couples clinical trials, each written for real people, not researchers. We’re tracking 89 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06659315Recruiting
Preventing HIV transmission from mom to baby for depressed mothers in Malawi
This study tests a program to help pregnant women with HIV who also have depression, and their partners, reduce the risk of passing HIV to their babies. The program includes support for mental health and HIV care.
ZombaAges 18 years+ - NCT06639932Recruiting
Wellness intervention for Chinese male couples with different HIV status
This study tests a wellness program for male couples in Hong Kong where one partner is HIV-positive and the other is HIV-negative. It aims to help couples improve their relationship and health together.
Xiamen, FujianAges 18 years+ - NCT06570278Recruiting
Genetic testing for unusual diabetes types
This study uses advanced genetic testing to find hidden causes of diabetes that doesn't fit the usual types. It may help people whose diabetes was diagnosed before age 46, who are not overweight, and who have certain unusual features like family history or early complications.
AmiensAges 18 years+ - NCT06276530Recruiting
Lung surgery: large incision vs. robotic approach and breathing
This study compares how different types of lung surgery (a large incision vs. robotic-assisted small cuts) affect your posture and breathing. It aims to help doctors choose the best approach for recovery.
ParisAges 18 years+ - NCT06501677Recruiting
Web program for couples concerned about drinking
This trial tests a web-based program for couples where one partner is concerned about their drinking. You and your partner will use a smartphone app to share daily feelings and drinking habits, with the goal of reducing risky drinking.
Portland, OregonAges 18 years+ - NCT06389175Enrolling by invitation
Non-invasive ear stimulation for depression
This study uses a gentle, non-invasive device that stimulates the vagus nerve in your ear to see if it can improve how your stomach and brain communicate, which may help with depression symptoms.
BonnAges 18–55 - NCT06296849RecruitingPhase 2
Quit smoking together as a couple with financial incentives
This trial tests if offering money rewards can help couples who both smoke to quit together. You and your partner would both join the program and get support to stop smoking.
Athens, GeorgiaAges 18 years+ - NCT06194851RecruitingPhase 2
Oxytocin nasal spray plus couples therapy for Veterans with PTSD
This study tests whether a nasal spray of oxytocin (a natural hormone) can boost the effects of a brief couples therapy for Veterans with PTSD. You and your partner would receive either the spray or a placebo (inactive spray) during therapy sessions to see if it helps reduce PTSD symptoms and improve relationship satisfaction.
San Diego, CaliforniaAges 18 years+ - NCT06132581Recruiting
Brain stimulation for pleasure loss in depression
This study tests a new type of brain stimulation to see if it can help people with depression who have lost the ability to feel pleasure. It uses MRI scans to guide the treatment and may help improve motivation and goal-setting.
Tallahassee, FloridaAges 18–65 - NCT04842162RecruitingPhase 2
Near-infrared dye imaging to help remove all mouth/throat cancer
This Phase 2 study tests a special camera and dye during surgery to help surgeons confirm they removed all cancer at the edge of the removed tissue. If it works, it may lower the chance of cancer being left behind after oral cavity or oropharynx squamous cell cancer surgery.
AnderlechtAges 18 years+ - NCT05175300Recruiting
Vitamin E hip implant for young, active hip replacements
This study tests a hip replacement implant that uses Vitamin E–doped material to see how well it works for young, active adults. It’s meant for people who need a total hip replacement, and compares outcomes over follow-up visits.
LyonAges 18–65 - NCT05515224Recruiting
Study for adults 65+ with memory concerns
This study looks at ways to help older adults with new or ongoing memory or thinking concerns. You may be able to take part if you’re 65 or older, have cognitive concerns, can complete study visits in English or Spanish, and are able to see and hear well enough for assessments.
Bloomington, IndianaAges 65 years+ - NCT05433129Recruiting
Test of brain blood-flow control using near-infrared light
This study uses a non-invasive light test on the forehead to measure how your brain regulates its blood flow. It’s meant to help researchers understand brain circulation control in healthy people.
Winnipeg, ManitobaAges 18 years+ - NCT04867187Recruiting
Brain stimulation plus mirror therapy for nerve pain
This trial tests whether a noninvasive brain stimulation treatment (repeated TMS) combined with mirror therapy can reduce nerve pain. It may help people whose nerve pain has lasted for months and hasn’t improved enough with usual medicines.
BronAges 18–85 - NCT03746964Recruiting
MRI study of the heart’s aorta before planned surgery
This study uses a special MRI scan to measure how the ascending aorta (a large blood vessel) moves and behaves before planned surgery. It may help doctors better understand the mechanics of an aortic aneurysm and improve future surgical planning.
DijonAges 18 years+ - NCT04298255Recruiting
Testicular injection therapy for certain causes of male infertility
This trial studies a special lab procedure where selected immature sperm cells are injected to help infertile couples achieve pregnancy. It is designed for couples where the man has a specific type of sperm-making problem found during a testicular sperm extraction.
Winston-Salem, North CarolinaAges 18 years+ - NCT02596490Recruiting
Couple meditation program for metastatic lung cancer and partners
This study tests whether a couple-based meditation program can help people with stage IV non-small cell lung cancer and their romantic partners cope better during treatment. It looks at the experience of both the patient and their partner, not just the patient alone.
Houston, TexasAges 18 years+
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Common questions
- Are there clinical trials for couples?
- Yes. Clin2 currently lists 89 recruiting couples studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a couples trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a couples trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.