Clinical trials
Couples clinical trials
Below are recruiting couples clinical trials, each written for real people, not researchers. We’re tracking 97 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03401879Recruiting
Study eye blood-flow changes in multiple sclerosis
This study measures how blood flow in the eye changes in people with relapsing-remitting multiple sclerosis (RRMS) who previously had optic neuritis. The goal is to understand eye/brain blood-flow signals and how they may relate to MS.
Vienna, AustriaAges 18 years+ - NCT03779009Recruiting
Study mapping sentinel lymph nodes to guide colon cancer surgery
This trial looks at a minimally invasive surgery approach for people with colon adenocarcinoma that has not spread to lymph nodes or other organs. The team will use special mapping tests on the sentinel lymph node to better understand the cancer spread and help guide treatment decisions.
GhentAges 18 years+ - NCT03870230Recruiting
Study of eye blood-flow signals in glaucoma and healthy eyes
This study compares eye blood-flow/brain-eye communication signals in people with glaucoma (or high eye pressure) versus people with normal eye tests. It may help researchers understand how glaucoma develops and progresses.
ViennaAges 18 years+ - NCT04062565RecruitingPhase 3
Testing treprostinil plus riociguat for advanced pulmonary artery hypertension
This study tests whether taking injected treprostinil together with riociguat can improve how the heart and lung blood vessels work in people with advanced pulmonary artery hypertension (PAH). It may help improve blood-flow measurements and the structure of the heart.
Tucson, ArizonaAges 18 years+ - NCT04842162RecruitingPhase 2
Near-infrared dye imaging to help remove all mouth/throat cancer
This Phase 2 study tests a special camera and dye during surgery to help surgeons confirm they removed all cancer at the edge of the removed tissue. If it works, it may lower the chance of cancer being left behind after oral cavity or oropharynx squamous cell cancer surgery.
AnderlechtAges 18 years+ - NCT04867187Recruiting
Brain stimulation plus mirror therapy for nerve pain
This trial tests whether a noninvasive brain stimulation treatment (repeated TMS) combined with mirror therapy can reduce nerve pain. It may help people whose nerve pain has lasted for months and hasn’t improved enough with usual medicines.
BronAges 18–85 - NCT05197972Recruiting
Hypnosis and heart-breathing training to reduce cancer surgery anxiety
This study tests whether guided “heart-breathing” and hypnosis (through an app) can lower anxiety before cancer surgery. It may help you feel calmer in the days leading up to the operation.
Montpellier, HéraultAges 18 years+ - NCT05515224Recruiting
Study for adults 65+ with memory concerns
This study looks at ways to help older adults with new or ongoing memory or thinking concerns. You may be able to take part if you’re 65 or older, have cognitive concerns, can complete study visits in English or Spanish, and are able to see and hear well enough for assessments.
Bloomington, IndianaAges 65 years+ - NCT05650905Recruiting
Eye and blood-vessel function study after COVID-19
This study measures how well the nerves in your retina and the tiny blood vessels in your eye “couple” (work together) after COVID-19. It may help researchers understand eye-related effects of COVID-19 and long COVID, and how these processes change over time.
Vienna, State of ViennaAges 18 years+ - NCT05655091RecruitingPhase 2
Personalized IV antibiotics for serious Staph aureus infections
This Phase 2 study tests whether continuous IV antibiotics plus “drug level monitoring” (TDM) works better than the usual treatment for complicated Staph aureus infections. It may help ensure the antibiotic dose stays in an effective range while you’re being treated.
BaselAges 18 years+ - NCT05865314Recruiting
Nutrition plus early therapy for adults in long ICU stays
This trial studies whether a planned nutrition plan, along with early physiotherapy (physical therapy), can improve outcomes for adults who expect to stay in the ICU for at least 7 days. It includes people who need feeding through a tube and/or special IV nutrition while on a breathing machine.
Geneva, Canton of GenevaAges 18 years+ - NCT06124950Recruiting
Couples program to prevent violence during IVF
This study tests a program to help couples communicate better and reduce stress during IVF, and whether it can prevent intimate partner violence. If you are a couple starting your first or second IVF cycle due to female infertility, you may be eligible to join.
BeijingAges 18 years+ - NCT06132581Recruiting
Brain stimulation for pleasure loss in depression
This study tests a new type of brain stimulation to see if it can help people with depression who have lost the ability to feel pleasure. It uses MRI scans to guide the treatment and may help improve motivation and goal-setting.
Tallahassee, FloridaAges 18–65 - NCT06172907Recruiting
Support for young adults with cancer and their partners
This study offers support to young adults (ages 25-39) with cancer and their partners. It aims to help couples manage stress during or after cancer treatment.
Boston, MassachusettsAges 25–39 - NCT06190210Recruiting
Brain blood flow study in infants with heart defects
This study measures how well blood flows to the brain in infants with serious heart defects. The results may help doctors understand and protect brain development before and after heart surgery.
Leuven, Vlaams-BrabantAges Up to 6 months - NCT06194851RecruitingPhase 2
Oxytocin nasal spray plus couples therapy for Veterans with PTSD
This study tests whether a nasal spray of oxytocin (a natural hormone) can boost the effects of a brief couples therapy for Veterans with PTSD. You and your partner would receive either the spray or a placebo (inactive spray) during therapy sessions to see if it helps reduce PTSD symptoms and improve relationship satisfaction.
San Diego, CaliforniaAges 18 years+ - NCT06409754Recruiting
Brain-computer interface for arm recovery after stroke
This trial tests a brain-computer interface system that helps move your arm using electrical stimulation. It is for people who have had a stroke at least 6 months ago and have lasting weakness in one arm.
Mexico City, Mexico CityAges 18 years+ - NCT07692646Recruiting
Fasting's effect on fat burning and energy in cells
This study looks at how fasting changes the way your body burns fat and how cells produce energy. If you are a healthy adult of normal weight or living with obesity, you may help researchers understand the effects of fasting on metabolism.
CopenhagenAges 18–40 - NCT06490887Recruiting
Spine unit modeling with high-throughput analysis (SUIT)
This study looks at cells from people with degenerated discs or from donated fat or placenta tissue. It aims to understand how these cells work and might help develop new treatments for back pain.
Milan, MIAges 18–60 - NCT06501677Recruiting
Web program for couples concerned about drinking
This trial tests a web-based program for couples where one partner is concerned about their drinking. You and your partner will use a smartphone app to share daily feelings and drinking habits, with the goal of reducing risky drinking.
Portland, OregonAges 18 years+ - NCT06570278Recruiting
Genetic testing for unusual diabetes types
This study uses advanced genetic testing to find hidden causes of diabetes that doesn't fit the usual types. It may help people whose diabetes was diagnosed before age 46, who are not overweight, and who have certain unusual features like family history or early complications.
AmiensAges 18 years+ - NCT06660797Recruiting
Irrigation methods for root canal treatment
This trial tests different ways to flush and clean inside a tooth during root canal treatment. It aims to see which method best reaches deep into the tooth and reduces bacteria.
TantaAges 18–40 - NCT06705712Recruiting
Exercise, fertility, and pregnancy loss in couples trying to conceive
This study looks at how physical activity affects a couple's chances of getting pregnant and the risk of early pregnancy loss. If you are a woman with a male partner and just starting to try for a baby, this trial may help you understand how your activity levels relate to fertility.
AarhusAges 18–49 - NCT07071259Recruiting
Brain activity and structure study in healthy adults
This study looks at how your brain's electrical activity relates to its structure using safe, non-invasive techniques (TMS, EEG, and MRI). It's a chance to learn more about how the healthy brain works, and you'll be asked to have brain scans and a mild stimulation session.
MarseilleAges 18–35
Hear when a new Couples trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for couples?
- Yes. Clin2 currently lists 97 recruiting couples studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a couples trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a couples trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.