Clinical trials
Critically Ill clinical trials
Below are recruiting critically ill clinical trials, each written for real people, not researchers. We’re tracking 352 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06697470Recruiting
Ultrasound and fluid monitoring in the ICU
This study uses ultrasound and electrical impedance (skin electrodes) to track fluid balance in the muscles and tissues of ICU patients. It aims to see if these tools can help doctors better manage fluids during your stay.
Boussu, HainautAges 18 years+ - NCT06702813Recruiting
High-frequency vibration breathing treatment for ICU patients
This trial tests a device called MetaNeb that delivers high-frequency vibrations to help clear mucus and open collapsed air sacs in the lungs. It is designed for patients in the ICU who are awake, alert, and have trouble breathing or need extra oxygen.
Shanghai, Shanghai MunicipalityAges 1.5 years–80 years - NCT07632716Recruiting
Blood marker to predict ICU patient outcomes
This study measures a specific blood protein (carbohydrate-deficient transferrin) when patients arrive at the hospital to see if it can predict how well they'll do in the intensive care unit. Understanding this marker might help doctors better plan care for critically ill patients.
ViennaAges 18 years+ - NCT07330505Recruiting
Checking blood pressure monitor setup in the ICU
This study looks at how doctors set up the blood pressure monitors in the ICU. It checks if the position of the monitor affects the readings, and it may help improve care for patients on breathing machines and blood pressure support.
GothenburgAges 18 years+ - NCT06714240Recruiting
Extra protein to support muscle strength in ICU
This study tests whether giving extra protein through a feeding tube can help ICU patients maintain muscle strength. It may be an option for people who are expected to stay in the ICU for at least a week and need a breathing machine.
Hasselt, LimburgAges 18 years+ - NCT06766461RecruitingPhase 4
Optimizing antibiotic dosing in ICU patients with septic shock
This trial checks if giving higher doses of beta-lactam antibiotics (a type of strong antibiotic) right from the start helps people in the ICU with septic shock. It aims to find the best dose to fight the infection quickly.
RotterdamAges 18 years+ - NCT06775106Recruiting
Breath test to find lung infections faster
This study tests a new breath analysis method to quickly diagnose respiratory infections in ICU patients on breathing machines. If successful, it could lead to faster treatment for serious lung conditions.
Portland, OregonAges 18–120 - NCT06791889Recruiting
Tracking bacteria in blood of ICU sepsis patients
This study uses a highly sensitive blood test (DdPCR) to quickly find and monitor harmful bacteria in ICU patients with sepsis, aiming to improve early detection and treatment.
WuhanAges 18 years+ - NCT06814457Recruiting
Nursing care bundle for swallowing after breathing tube removal in children
This trial tests a special nursing care plan to help children who had a breathing tube eat and drink safely after it's removed. It aims to reduce swallowing problems in the intensive care unit.
Kafr ash Shaykh, Kafr Ash Shaykh, Kafr el-Sheikh, Egypt,Ages 6–18 - NCT06822465Recruiting
Gut bacteria study in critically ill patients
This study looks at the bacteria in the gut of people who are very ill in the hospital. It may help doctors understand how gut health affects recovery.
Hyde Park, IllinoisAges 18–85 - NCT06829732Recruiting
Closed-loop oxygen control for ICU patients on a breathing machine
This trial tests a closed-loop system that automatically adjusts the oxygen level in your breathing tube, aiming to keep your oxygen levels in a safe range with less need for manual changes. It may help if you are in the ICU, need a breathing machine, and have low blood oxygen despite receiving extra oxygen.
Sabadell, BarcelonaAges 18 years+ - NCT06835491RecruitingPhase 3
Amiodarone to prevent heart rhythm problems after cardiac arrest
This trial tests whether giving the drug amiodarone early can prevent dangerous heart rhythm problems in patients who survived a cardiac arrest with a shockable rhythm. If it works, it could help more people recover.
AmiensAges 18 years+ - NCT06867354Recruiting
Breathing difficulty in obese patients during weaning from ventilator
This study looks at how often obese patients have trouble breathing when doctors try to remove the breathing tube (weaning) in the ICU. The goal is to understand what causes this and how it affects recovery.
Paris, ParisAges 18 years+ - NCT06928649Recruiting
Studying cell damage in critically ill ICU patients
This trial looks at specific cell damage processes (called ferroptosis and pyroptosis) in very sick ICU patients. The goal is to learn more about these processes so doctors can better treat life-threatening organ failure caused by conditions like sepsis, trauma, or severe bleeding.
EdegemAges 18 years+ - NCT06937918Recruiting
Fluid management guide for septic shock patients
This study tests a computer software that helps doctors decide how much fluid to give patients in septic shock. It aims to improve blood pressure and oxygen delivery without causing fluid overload.
Bangkok Noi, BangkokAges 18 years+ - NCT06966869Recruiting
Fentanyl patch absorption in ICU patients
This study looks at how well fentanyl patches work in ICU patients who are not stable. It aims to understand if the patch is absorbed properly in these patients.
Tel Aviv, IsraelAges 18–70 - NCT06991777Recruiting
Precision sedation in the ICU
This trial tests a precise way to manage sedation for intensive care patients who need it for more than 24 hours. It aims to improve recovery and reduce side effects.
Oslo, OsloAges 18 years+ - NCT06997822Recruiting
Recovery program for ICU survivors
This trial tests a program to help people who were on a breathing machine in the ICU recover after leaving the hospital. It uses a smartphone app to guide your recovery at home.
TaipeiAges 18 years+ - NCT06999161Recruiting
Tracking Antibiotic Levels in ICU Brain Injury Patients
This study monitors the amount of certain antibiotics in the blood of patients with acute brain injury in the intensive care unit. It aims to make sure the antibiotics are at the right level to fight infection, especially in patients whose kidneys are clearing drugs faster than normal.
NîmesAges 18 years+ - NCT07013175Recruiting
Wise Choices in the Intensive Care Unit
This study looks at how decisions are made in the ICU. It may help improve care for adult patients in Swedish intensive care units.
StockholmAges 18 years+ - NCT07017517Recruiting
Exercise therapy for weakness after sepsis in the ICU
This trial tests whether adding physical therapy early in the ICU can help people with sepsis regain strength and reduce muscle weakness. It focuses on patients who need a breathing tube for at least a week and have a high level of organ failure.
Santiago, Metropolitan RegionAges 18 years+ - NCT07026656Recruiting
Quick diagnosis of ventilator pneumonia in critically ill children
This study tests a new way to quickly diagnose pneumonia in children on breathing machines in the ICU. It uses information from the body and germs to find the right treatment faster.
CambridgeAges 1 month–16 years - NCT07027813Recruiting
Ambulance video care for children
This trial tests whether using a tablet computer and video connection in an ambulance helps doctors and emergency workers care for children during the ride to the hospital. It aims to see if this approach is practical and improves treatment.
Karachi, SindhAges 1 minute–14 years - NCT07032987Recruiting
Improving sedation with a new care plan for ICU patients
This trial tests a new sedation protocol for adults in intensive care who need strong pain relief or sedation medicines. It aims to make sedation safer and more comfortable, and includes people on ECMO (a heart-lung machine) or a ventilator (breathing machine) for severe breathing problems.
London, LondonAges 18–100
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Common questions
- Are there clinical trials for critically ill?
- Yes. Clin2 currently lists 352 recruiting critically ill studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a critically ill trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a critically ill trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.