Clinical trials
Cystic Fibrosis clinical trials
Below are recruiting cystic fibrosis clinical trials, each written for real people, not researchers. We’re tracking 157 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06512064Recruiting
Breath sound test for lung health
This study tests a new device that listens to your breathing to check lung health. It is for healthy people and those with asthma, COPD, CF, or other airway diseases.
Indianapolis, IndianaAges 8–70 - NCT06539169Recruiting
Following people with rare diseases over time
This study follows people with rare diseases over time to learn more about how these conditions progress and how they are treated. Joining may help researchers understand your disease better and find better ways to care for others.
Los Altos, CaliforniaAges Any age - NCT06599892Recruiting
Cystic fibrosis care with highly effective modulators
This study looks at how cystic fibrosis care is organized when patients take highly effective CFTR modulator drugs. It aims to understand if care needs change for those on modulators compared to those who cannot take them.
LyonAges 6 years+ - NCT04509050Recruiting
Testing a highly effective CF medicine in young children
This study looks at how well a highly effective cystic fibrosis (CF) medicine works in infants and young children, and what biological changes it causes. It may help families understand whether the medicine improves CF function and related measures early in life.
Birmingham, AlabamaAges Up to 10 years - NCT06602869Recruiting
Cellular markers in cystic fibrosis with a certain lung infection
This study looks at special blood markers in people with cystic fibrosis who have or haven't been treated for a lung infection caused by nontuberculous mycobacteria. The goal is to better understand the body's response, which could lead to better treatments.
MontpellierAges 18 years+ - NCT06603246RecruitingPhase 1
Study of inhaled GDC-6988 for mucus lung diseases
This study tests an inhaled medicine (GDC-6988) to see if it is safe and helps clear mucus from the lungs in people with mucus-related lung diseases like chronic bronchitis, COPD, or bronchiectasis. You may qualify if your lung function is fairly stable and you produce daily mucus.
Birmingham, AlabamaAges 18 years+ - NCT06654752Recruiting
Simpler treatment for lung flare-ups in kids with CF
This study tests a streamlined approach to managing sudden lung symptoms (pulmonary exacerbations) in children with cystic fibrosis. It aims to see if a simpler treatment plan works as well as standard care, which could mean less time in the hospital and fewer disruptions to daily life.
Birmingham, AlabamaAges 3–18 - NCT06683092Recruiting
Restarting triple therapy with close monitoring for side effects
This trial tests whether carefully restarting a triple-combination CFTR modulator (VTD) is safe and helpful for people with cystic fibrosis who had to stop or change Trikafta because of mental health side effects or liver injury. You will be closely monitored with surveys and daily diaries to ensure your safety.
Birmingham, AlabamaAges 6 years+ - NCT06797206Recruiting
CF in pregnancy and child health study
This study follows women with cystic fibrosis (CF) during pregnancy and after birth, and checks on their babies and young children. The goal is to learn more about how CF affects pregnancy and child development.
LondonAges Any age - NCT06810167RecruitingPhase 3
Testing tenapanor for cystic fibrosis-related constipation
This study tests whether the drug tenapanor can help people with cystic fibrosis who have constipation. It may be an option for those whose current treatments are not working well.
Boston, MassachusettsAges 18–75 - NCT06998043RecruitingPhase 2
Phage therapy for cystic fibrosis with pseudomonas lung infection
This trial tests a new treatment using phages (viruses that kill bacteria) for people with cystic fibrosis who have a chronic pseudomonas lung infection. It aims to see if adding phages to your usual care can help control the infection.
Birmingham, AlabamaAges 18 years+ - NCT07035990RecruitingPhase 1
Testing combinations of three study drugs in healthy volunteers
This trial tests how safe and tolerable three different study drugs (SION-451, SION-2222, and SION-109) are when taken together in healthy adults. The goal is to find a good dose combination for future studies in people with cystic fibrosis.
Brisbane, QueenslandAges 18–55 - NCT07071324Recruiting
CF Wellness Program for Fatigue
This wellness program tests if coaching sessions can help people with cystic fibrosis who feel tired. It is a remote program you can join using your phone or computer, as long as you get CF care at a participating center.
Denver, ColoradoAges 18 years+ - NCT07083557Recruiting
Validation study for lab tests on hormones and metabolism
This study checks if lab tests used for hormone, heart, metabolism, and muscle disorders are accurate and reliable. You might be eligible if you are an adult with a body mass index between 16 and 60.
Columbia, MissouriAges 18–100 - NCT07148739RecruitingPhase 4
Ensuring Best Access to CF Treatment
This study tests whether people with cystic fibrosis who are already on a triple combination CFTR modulator can stay on their treatment without interruptions or problems. It aims to make sure everyone gets the best, most consistent treatment for their CF.
Birmingham, AlabamaAges 3 years+ - NCT07202910Recruiting
Validating liver imaging in children
This study tests if non-invasive imaging (like ultrasound) can replace liver biopsies in children with liver disease. It may help avoid the need for a needle biopsy in the future.
Gothenburg, Västra Götaland CountyAges Up to 25 years - NCT07312734Recruiting
Testing new ways to find lung germs in CF
This study tests a new method to detect bacteria in the lungs of people with cystic fibrosis (CF) by analyzing mucus samples. It aims to improve how we diagnose and treat lung infections.
La Jolla, CaliforniaAges 16 years+ - NCT07274631Recruiting
Study of inflammatory lung diseases
This study collects information from people with various inflammatory lung conditions, like asthma or COPD, to better understand them and improve treatment. Healthy volunteers are also needed for comparison.
ReimsAges 18 years+ - NCT07303621Recruiting
Study of Trikafta in children with cystic fibrosis
This study looks at how the drug Trikafta (also called Kaftrio) works in children aged 2 to 17 with cystic fibrosis. The goal is to learn how the body processes the medicine so doctors can find the best dose.
BronAges 2–17 - NCT06985225Recruiting
Study of mucus plugs and lung function in mucus-related lung disease
This study looks at how mucus plugs affect air flow in the lungs. It may help find new ways to treat people with lung conditions like cystic fibrosis, severe asthma, COPD, or bronchiectasis.
Kansas City, KansasAges 18–65 - NCT00943514Recruiting
Study of bronchiectasis and why infections keep coming back
This study follows children (age 5+) and adults with bronchiectasis or ongoing/repeated lung infections to learn what makes infections more likely. It mainly looks at non–cystic fibrosis causes, but may include some related conditions to compare differences.
Bethesda, MarylandAges 5–100 - NCT01851642Recruiting
Study how lung disease affects white blood cells
This study looks at how lung disease changes a type of blood cell called white blood cells. It may help researchers understand what’s happening in the lungs and how to better monitor or treat lung problems.
Gainesville, FloridaAges 18 years+ - NCT02740868RecruitingPhase 2
Breathing MRI using xenon gas to study lungs
This trial uses a special breathing MRI (you breathe a gas mixture) to measure how well your lungs work. It studies healthy kids and people with lung conditions like cystic fibrosis or asthma, and it may help researchers better understand lung function and flare-ups.
Toronto, OntarioAges 8 years+ - NCT03161808Recruiting
CF rare mutation blood and tissue sample collection study
This study collects cells from people with cystic fibrosis (CF) caused by rare CFTR gene changes. The goal is to build a cell bank for future research, which may help scientists develop better tests and treatments for rare CF types.
Birmingham, AlabamaAges 17 years+
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Common questions
- Are there clinical trials for cystic fibrosis?
- Yes. Clin2 currently lists 157 recruiting cystic fibrosis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cystic fibrosis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cystic fibrosis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.