Clinical trials
Cystic Fibrosis clinical trials
Below are recruiting cystic fibrosis clinical trials, each written for real people, not researchers. We’re tracking 155 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05860803Recruiting
Breathing training plus exercise to improve breathing capacity
This study looks at whether breathing exercises combined with exercise training can improve how much and how well you can breathe during activity in people with non-cystic fibrosis bronchiectasis. It may help by improving breathing efficiency and exercise tolerance, but you must be stable and healthy enough to safely exercise.
Jacksonville, FloridaAges 21–80 - NCT07245407Recruiting
Study of bronchiectasis types in Chinese patients
This study looks at different types of bronchiectasis in Chinese patients to understand the disease better. It may involve additional tests like lung function and questionnaires.
Beijing, Beijing MunicipalityAges Any age - NCT06775340RecruitingPhase 2
Testing an experimental drug for bronchiectasis
This study tests a new medicine for people with non-cystic fibrosis bronchiectasis. It aims to see if the drug can help reduce symptoms and improve quality of life.
Guangzhou, GuangdongAges 18–75 - NCT06587126Recruiting
Can a Cough Monitor Work in Children?
This study tests a way to monitor coughing in children at home, including children with cystic fibrosis and healthy children. It will help researchers learn how well a cough monitor works in real life.
Aurora, ColoradoAges 1–18 - NCT07283770RecruitingPhase 1
Safety study of VX-581 in healthy people
This trial tests the safety of a new medicine called VX-581. It is given to healthy volunteers to see how the body processes the drug and if it causes any side effects.
Overland Park, KansasAges 18–55 - NCT03052283Recruiting
Abdominal symptom score test for people with cystic fibrosis
This trial helps create and check a patient-friendly questionnaire that measures abdominal (belly) involvement in cystic fibrosis. It may help your care team better track symptoms over time.
Brandenburg an der HavelAges Any age - NCT03587961RecruitingEarly Phase 1
Personalized testing to find the best CF medicine for you
This early study tests an individualized approach (“theratyping”) to match your cystic fibrosis (CF) to the CFTR medicine that may work best for your specific genetic change. It may help find a more tailored treatment plan and see how your body responds, while using medicines that are already approved for some people with CF.
Birmingham, AlabamaAges 6 years+ - NCT03925194RecruitingPhase 2
Test Anakinra injections under the skin for cystic fibrosis
This Phase 2 study tests whether a medicine called anakinra, given as under-the-skin injections, is safe and may improve lung outcomes in adults with cystic fibrosis. You may be able to join if you meet specific breathing and lab criteria and can follow the study schedule.
Heidelberg, Baden-WurttembergAges 12 years+ - NCT04294043RecruitingPhase 1
Gallium IV study for adults with cystic fibrosis and NTM lung infection
This Phase 1 study tests whether an IV medicine called gallium can treat hard-to-treat lung infections (NTM) in adults with cystic fibrosis. It is mainly for people who have not been treated yet for NTM or who have NTM that has not cleared despite antibiotics.
Birmingham, AlabamaAges 18 years+ - NCT04624490RecruitingPhase 1
Lung function MRI using a special gas in volunteers
This Phase 1 study tests a lung scan that uses a special gas and MRI to measure how well your lungs work. It includes healthy volunteers and people with lung disease to see how well the scan works and how safe it is.
Kansas City, KansasAges 3 years+ - NCT04793867Recruiting
MRI study of lung differences in cystic fibrosis and bronchiectasis
This study uses MRI scanning to better understand how the lungs differ in people with cystic fibrosis (CF) and in people with non-CF bronchiectasis. The results may help doctors understand disease changes over time and guide future care, especially for children and teens.
Cincinnati, OhioAges 5–100 - NCT05359991Recruiting
Exercise study in children and teens with lung or blood conditions
This study tests how safe and effective a structured exercise program is for children and teens. It also compares results between children with sickle cell disease, cystic fibrosis, and healthy peers (and some teens after COVID-19 infection).
Irvine, CaliforniaAges 10–17 - NCT05501587Recruiting
Respiratory Health Registry measuring lung function in different groups
This registry study collects information and measures lung function to better understand respiratory health across people with cystic fibrosis, other lung diseases, and healthy volunteers. Your results may help researchers track lung health and improve future research and care.
Vancouver, British ColumbiaAges birth–99 years - NCT05517655RecruitingPhase 4
Cystic fibrosis blood/sweat check using MRI in children
This study looks at new “imaging biomarkers” (MRI measurements) in children with cystic fibrosis (CF). It mainly aims to see how MRI findings might relate to starting the recommended CF triple-combination therapy.
Kansas City, KansasAges 6–8 - NCT05704036RecruitingPhase 4
Estrogen use and bone health in women with cystic fibrosis
This observational study looks at how taking (or not taking) estrogen affects bone health in women with cystic fibrosis (CF). If you may have low estrogen, it also explores whether estrogen levels and symptoms relate to bone density over time.
Baltimore, MarylandAges birth–100 years - NCT06032273Recruiting
Lung Transplant Study for CF Patients and Their Caregivers
This study looks at a website-based program to support people with cystic fibrosis (CF) and their caregivers, helping them prepare for a possible lung transplant. It aims to ease stress, provide information, and improve the transplant journey.
Seattle, WashingtonAges 18 years+ - NCT06045702Recruiting
Study of CFTR gene in epididymal cells from surgery
This study collects a small tissue sample from the epididymis during planned surgery. The sample is used to study how the CFTR gene works, which may help understand fertility problems in men with cystic fibrosis.
BrestAges 18 years+ - NCT06147414Recruiting
Blood test for genetic disorders in pregnancy
This study tests a safer blood test to check for certain genetic disorders during pregnancy, instead of an invasive procedure like amniocentesis. It's for pregnant women who are at risk of passing on a known genetic condition.
ParisAges 18 years+ - NCT06242795RecruitingPhase 4
Hypertonic saline for non-cystic fibrosis bronchiectasis
This trial tests whether inhaling a saltwater solution (hypertonic saline) twice a day for 12 weeks can help people with bronchiectasis who have a chronic cough and have had flare-ups in the past. It aims to see if this treatment reduces mucus and improves quality of life.
Chapel Hill, North CarolinaAges 18 years+ - NCT06302270Recruiting
Kaftrio during pregnancy and after birth
This study looks at how the cystic fibrosis medication Kaftrio works during pregnancy and after childbirth. It follows women with cystic fibrosis who are already taking Kaftrio and their newborn babies.
StockholmAges Up to 50 years - NCT06339593RecruitingEarly Phase 1
Using MRI to Monitor CF Lung Health
This study uses MRI scans to monitor lung health in teens and young adults with cystic fibrosis who are taking Trikafta. It aims to find better ways to track how the disease affects the lungs over time.
Cincinnati, OhioAges 12–21 - NCT06504589Recruiting
Study for CF treatments for people without modulators
This study tests new treatments for cystic fibrosis in people who cannot take or choose not to take current CFTR modulators. It aims to find better options for managing CF.
Birmingham, AlabamaAges 12 years+ - NCT06512064Recruiting
Breath sound test for lung health
This study tests a new device that listens to your breathing to check lung health. It is for healthy people and those with asthma, COPD, CF, or other airway diseases.
Indianapolis, IndianaAges 8–70 - NCT06539169Recruiting
Following people with rare diseases over time
This study follows people with rare diseases over time to learn more about how these conditions progress and how they are treated. Joining may help researchers understand your disease better and find better ways to care for others.
Los Altos, CaliforniaAges Any age
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Common questions
- Are there clinical trials for cystic fibrosis?
- Yes. Clin2 currently lists 155 recruiting cystic fibrosis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cystic fibrosis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cystic fibrosis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.