Clinical trials
Depressed clinical trials
Below are recruiting depressed clinical trials, each written for real people, not researchers. We’re tracking 1,504 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07667738RecruitingPhase 2
Parent support program in Peru for parents of young children
This study tests a therapy program called CETA for parents in a specific area of Lima, Peru. It aims to help parents improve their mental health, which may also benefit their children ages 4 to 6.
LimaAges 18 years+ - NCT06210100Recruiting
Brain stimulation for self-harm in teens with depression
This study tests a type of brain stimulation (called aiTBS) that uses magnetic pulses to help reduce self-harm and suicidal thoughts in teens with depression. It's for teens who are in the hospital and have been hurting themselves on purpose.
Dali, YunnanAges 12–18 - NCT06515236Enrolling by invitation
A study of depression treatment for teens from minority groups
This study is testing a new way to help teens (ages 12–18) from racial or ethnic minority groups who are feeling depressed. It looks at how working with a specially trained therapist can improve their mental health.
New Haven, ConnecticutAges 12 years+ - NCT06362538Recruiting
Heart health prevention program
This trial tests a program to help prevent heart problems in people who have not had a heart attack or stroke. It is for adults aged 30 and older.
Cotignola, RavennaAges 18–30 - NCT06413849Recruiting
Phone coaching with a picture-story book for dementia caregivers
This study tests if talking with a coach by phone and reading a story-based book can help family caregivers of people with dementia feel better. You'll get a free book and weekly coaching calls to help manage your mood.
Hong Kong SARAges 18 years+ - NCT02726061Recruiting
Online psychological support for depression
This study tests an internet-based (online) psychological support program for adults who are feeling depressed. It may help participants by offering structured support without needing in-person visits.
Lebanon, New HampshireAges 18 years+ - NCT07084454Enrolling by invitationPhase 3
Remote geriatric care for older adults starting cancer treatment
This trial tests whether remote health assessments and support can improve care for adults 65+ who are starting a new cancer treatment. You'd participate from home via telehealth visits.
Rio de Janeiro, Rio de JaneiroAges 65 years+ - NCT07281729Enrolling by invitation
Suicide risk factors study for mood disorders
This study looks at why some people with mood disorders (like depression or bipolar disorder) think about or attempt suicide. By finding the risk factors, doctors hope to better prevent suicide. The study involves filling out questionnaires.
Shanghai, Shanghai MunicipalityAges 16–60 - NCT07048990Recruiting
Empowerment group therapy for Ukrainian adults affected by war
This trial tests a group therapy program designed to help Ukrainian adults cope with depression, anxiety, stress, or other war-related distress. It aims to see if this support is helpful and practical for people living in or from Ukraine.
Kyiv, Kyiv OblastAges 18 years+ - NCT07220460RecruitingPhase 2
Study of an oral drug for bipolar depression
This trial tests an experimental pill (ABB-932) for people with bipolar I or II disorder who are currently in a depressive episode. The goal is to see if the drug is safe and helps improve mood.
Phoenix, ArizonaAges 18–65 - NCT07217561Recruiting
Doula support program to improve mental health before and after birth
This trial tests whether extra training and resources for doulas can help pregnant people and new parents feel better emotionally. Doulas who join will learn new ways to support clients, and participants will get care from a trained doula.
Boston, MassachusettsAges Any age - NCT07152925Recruiting
Brain stimulation for impulse control in teens with self-injury
This trial tests whether a gentle electrical current applied to the scalp can improve impulse control in adolescents who harm themselves without wanting to die. The goal is to see if this non-invasive treatment can help reduce self-injury urges.
Hefei, AnhuiAges 12–22 - NCT07682753Recruiting
Mental health support for autistic college students
This study tests a mental health program for autistic college students who feel stressed, anxious, or down. You would join weekly sessions for 8 weeks to see if the program helps improve your well-being.
Edinburg, TexasAges 18–30 - NCT06936202Recruiting
Spirulina pill study for healthy adults
This study tests whether a supplement called spirulina (a type of algae) can improve mental health in healthy adults. You would take spirulina daily and have your mood and well-being checked over several weeks.
Phoenix, ArizonaAges 16–65 - NCT06713616RecruitingPhase 3
Esketamine vs. ketamine for hard-to-treat depression
This study compares the effectiveness of esketamine (Spravato) and another similar drug, ketamine, for adults with major depression that has not improved after trying at least two other antidepressants. It aims to find out which treatment works better.
Milford, ConnecticutAges 18 years+ - NCT06725277Recruiting
Observing ketamine and Spravato for depression
This study follows people who are already taking or about to start IV ketamine or Spravato® for hard-to-treat depression. Researchers want to learn more about how these treatments work in real life.
Milford, ConnecticutAges Any age - NCT07020572Recruiting
Teen mood support program (iMATTER) in primary care
This study tests a group program to help teenagers with mild to moderate depression symptoms feel better. It takes place in primary care and uses a phone, computer, or tablet for activities.
Philadelphia, PennsylvaniaAges 13–17 - NCT06387732Recruiting
Exercise for depression: how it works
This trial looks at how physical activity helps improve mood in people with moderate depression. You will be asked to take part in either brisk walking or stretching sessions, so the researchers can measure changes in your depression symptoms and brain function.
LondonAges 18–60 - NCT06968650Recruiting
Cocooned Moms Support Study
This study tests a program that offers extra support to Black women during pregnancy. It aims to help moms feel safe, connected, and healthy.
Miami, FloridaAges 18 years+ - NCT06725160Recruiting
Happiness coaching for moms and their young children
This trial tests a program that helps mothers with depression learn positive parenting skills to boost their child's emotional well-being. If you are a mother with high depressive symptoms and have a child between 4 and 6 years old, this study may be an option.
Pittsburgh, PennsylvaniaAges 4–99 - NCT05699226Recruiting
Testing whether adjusting ECT treatment helps depression outcomes
This study tests a way of adjusting (titrating) ECT treatment to improve outcomes in people with major depression or bipolar II. It’s mainly for those who already need ECT with right-side electrode placement.
Albuquerque, New MexicoAges 50 years+ - NCT07475039Recruiting
Friendly phone calls to support older adults
This study tests whether a program of friendly phone calls from trained volunteers can help older adults feel more connected and supported. If you are 65 or older and already receive home-delivered meals or other services, you may be able to join.
Gainesville, FloridaAges 55 years+ - NCT07653022Enrolling by invitation
Turkish symptom questionnaire for Turkish speakers with language barriers
This study tests a Turkish version of a questionnaire for Turkish-speaking patients who have psychological complaints but face language barriers. It aims to help doctors better understand their symptoms.
Jette, Brussels CapitalAges 18 years+ - NCT05655754RecruitingPhase 4
Tests anesthesia options for ECT in severe depression
This trial compares two anesthesia medicines—esketamine plus propofol versus methohexital—for people receiving ECT (electroconvulsive therapy) for severe depression. The goal is to see which anesthesia approach works better and is safer for patients during ECT.
ViennaAges 18 years+
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Common questions
- Are there clinical trials for depressed?
- Yes. Clin2 currently lists 1,504 recruiting depressed studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a depressed trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a depressed trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.