Clinical trials
Depression Anxiety Disorder clinical trials
Below are recruiting depression anxiety disorder clinical trials, each written for real people, not researchers. We’re tracking 455 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07645157RecruitingPhase 2
Sertraline and Probiotics for Teen Depression
This study tests whether combining an antidepressant medication (sertraline) with special bacteria supplements (probiotics) can help treat depression in teenagers ages 12–18. Researchers believe the probiotics may help the medication work better by improving gut health.
Chongqing, YuzhongAges 12–18 - NCT06480500RecruitingPhase 2
Online therapy and IV ketamine for severe depression with suicide risk
This study tests whether adding an online therapy (i-CBT) to intravenous (IV) ketamine is better than IV ketamine alone for people with treatment-resistant depression who are also thinking about suicide. You'll receive either ketamine or a comparison drug (midazolam), plus the online therapy, in a hospital setting.
Toronto, OntarioAges 21–65 - NCT06790641Recruiting
Supporting mental health during and after pregnancy
This study aims to improve mental health care for people during and after pregnancy. It involves interviews or focus groups with healthcare providers, peer mentors, and patients to understand how to make support services more helpful and accessible.
Shrewsbury, MassachusettsAges 18–70 - NCT05568498RecruitingPhase 2
Probiotic trial for depression in Parkinson’s disease
This Phase 2 study tests whether taking probiotics can improve depression and mood symptoms in people with Parkinson’s disease. It’s meant for those with mild to moderate depression and stable Parkinson’s and mood treatments.
Vancouver, British ColumbiaAges 40–80 - NCT06187090Recruiting
Supplement therapy for adults with autism
This trial tests whether a specific supplement can help adults with Level 1 autism. It is open only to Italian-speaking participants aged 18–35 who do not have other major mental health or brain conditions.
Udine, UDAges 18–35 - NCT06490315Enrolling by invitation
Studying OkeyMind for social anxiety in young people
This trial tests if a smartphone program called OkeyMind helps reduce social anxiety in young people aged 15-24. It also looks at whether the program is worth the cost.
Hong Kong, Hong KongAges 15–24 - NCT06212219Recruiting
EEG brain training to help arm recovery after stroke
This study tests whether a brain-training technique called neurofeedback can improve arm movement in people who recently had a stroke. It uses an EEG cap to measure your brain activity while you do arm exercises, helping you relearn how to move your affected arm.
ToulouseAges 18–99 - NCT07315516RecruitingPhase 2
Sleep and stress supplement study
This study tests a new supplement to help with sleep and stress. It is for adults who feel stressed and have sleep problems, but are otherwise healthy.
BrisbaneAges 18 years+ - NCT04245436RecruitingPhase 4
Testing antidepressants for teens with anxiety
This trial studies whether an antidepressant can help teens (ages 12–17) with anxiety disorders such as generalized, social, separation, or panic anxiety. It looks at both early and longer-term success of treatment, while monitoring safety closely with a caregiver.
Cincinnati, OhioAges 12–17 - NCT05538910Recruiting
Study brain links between depression and substance use
This study uses brain imaging and questionnaires to understand how substance use and depression are connected in the brain. It may help researchers identify biological patterns that could guide better treatments in the future.
Baltimore, MarylandAges 18–60 - NCT06678295Recruiting
CBT for social anxiety or body dysmorphic disorder
This study looks at how individual factors affect the success of cognitive behavioral therapy (CBT) for social anxiety or body dysmorphic disorder. You'll have therapy sessions and brain scans to see what works best for people like you.
Seattle, WashingtonAges 18–45 - NCT06776887Recruiting
Virtual reality exercises for burn recovery on legs
This trial tests whether virtual reality exercises can help people with leg burns improve balance and reduce depression and anxiety. It is for people who had a large thermal burn on their lower body at least 3 months ago.
GizaAges 35–55 - NCT04581902Recruiting
Study blood and brain markers in moderate to severe depression
This study looks at changes in depression “markers” to understand what treatments help and why. You’ll have non-invasive brain stimulation and scans before and after treatment, over about 8 weeks.
San Francisco, CaliforniaAges 18–70 - NCT05598034Recruiting
Brain stimulation with tDCS for moderate depression
This study tests whether a noninvasive brain stimulation called tDCS can improve depression symptoms. It also uses MRI scans, aiming to understand how brain changes may relate to symptom improvement.
Los Angeles, CaliforniaAges 20–55 - NCT05895747RecruitingPhase 2
5-HTP and creatine for adults with depression symptoms
This Phase 2 study tests whether adding 5-HTP and creatine can reduce depression symptoms in adults with major depressive disorder. It may help if your current depression treatment hasn’t been fully effective and you meet the safety and medical criteria.
Salt Lake City, UtahAges 18–65 - NCT06073886RecruitingPhase 2
Better brain stimulation for long-lasting concussion symptoms
This trial tests whether personalized brain stimulation can help people who have ongoing symptoms more than 20 on a standard concussion scale, such as headaches, dizziness, or trouble concentrating, after a mild head injury in the past year.
Westwood, Los Angeles, CaliforniaAges 18–65 - NCT06175104Recruiting
HeartGPS: Support for parents after a prenatal heart diagnosis
This study tests a counseling program for parents whose unborn baby has a serious heart condition called single ventricle. The program aims to help parents manage stress and support their baby's development before and after birth.
Los Angeles, CaliforniaAges 18 years+ - NCT06673407Recruiting
Group workshops for social anxiety in CU undergraduates
This study tests a group workshop program for undergraduates at CU Boulder who feel anxious in social situations or when speaking in public. The workshops are designed to help you face your fears step by step, with support from others.
Boulder, ColoradoAges 18–30 - NCT05877885Recruiting
Digital treatment for low motivation in older adults with depression
This study tests a digital therapy to improve apathy (feeling unmotivated or “checked out”) in people age 60+ who have depression. It also uses brain imaging (MRI) and questionnaires to see whether the treatment helps brain function linked to motivation.
Orlando, FloridaAges 60 years+ - NCT07033052Recruiting
Art therapy for anxiety and depression in teens
This trial tests whether art-based activities can help children and teens aged 8 to 17 who feel anxious or depressed. Parents must agree to let their child join.
Cleveland, OhioAges 8–17 - NCT07238920Recruiting
Brain training for heart health in people with coronary artery disease and anxiety
This trial tests a brain-training technique called neurofeedback, which uses a video game controlled by your brain activity to help your heart and nervous system work better. It is for people with both coronary artery disease and anxiety who want to improve their heart health and manage anxiety without medication.
Shenyang, LiaoningAges 18 years+ - NCT07244484Recruiting
Brain Training for Heart Health in Coronary Artery Disease with Anxiety
This trial tests a brain training technique (neurofeedback) to help people with coronary artery disease and anxiety. It aims to improve heart rate control by targeting a specific brain area.
Shenyang, LiaoningAges 18 years+ - NCT06521398Recruiting
Postpartum Care for Preterm NICU Babies
This study focuses on helping new mothers of preterm babies (born before 34 weeks) who are getting care in the NICU at HUP. It tests a program to support your transition home after giving birth, so you and your baby can thrive.
Philadelphia, PennsylvaniaAges 16 years+ - NCT06074250RecruitingPhase 2/Phase 3
Pregnancy, mood, and gut health study
This study tests whether a nutritional supplement can help prevent depression and anxiety during and after pregnancy. It looks at how the mother's gut bacteria may influence mood.
Toronto, OntarioAges 18–43
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Common questions
- Are there clinical trials for depression anxiety disorder?
- Yes. Clin2 currently lists 455 recruiting depression anxiety disorder studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a depression anxiety disorder trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a depression anxiety disorder trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.