Clinical trials
Depression, Anxiety clinical trials
Below are recruiting depression, anxiety clinical trials, each written for real people, not researchers. We’re tracking 479 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05830266Recruiting
Mindfulness program to help mother–baby bonding in pregnancy and after
This study tests a mindfulness-based program to improve mother–baby bonding by supporting mood, anxiety, and stress during and after pregnancy. It may help if you’re currently having higher-than-average depression, anxiety, or stress symptoms.
Tilburg, North BrabantAges 18 years+ - NCT05836090Recruiting
Family Spirit Strengths program for pregnant people and caregivers
This trial tests a family-focused program to support mental health and reduce risks related to substance use. It may help you if you’re pregnant or caring for a child 24 months or younger and you’re experiencing depression/anxiety and/or substance-use risk.
Chinle, ArizonaAges 14 years+ - NCT05868135Recruiting
Online guided therapy for depression and anxiety
This trial tests an internet-based (online) guided psychological program, called e-Meistring, for people with moderate depression plus panic disorder and social anxiety. It aims to see whether the program improves symptoms and is also worth the cost.
BergenAges 18 years+ - NCT05897021Recruiting
Writing exercises to ease stress for sexual minority veterans
This study tests whether guided “expressive writing” helps reduce distress linked to sexuality-based stress. It targets veterans who have meaningful anxiety or depression symptoms and ongoing stress related to their sexual identity.
Boston, MassachusettsAges 18 years+ - NCT05897619Recruiting
CBT skills app for pregnancy and postpartum stress and coping
This study tests whether a new phone app that teaches “cognitive behavioral therapy” (CBT) skills is helpful and easy to use for people who are pregnant or recently gave birth. It also checks safety and whether participants feel the app is acceptable to use over time.
New York, New YorkAges 18 years+ - NCT05989451Recruiting
Talk therapy for depression and anxiety
This trial tests a type of talk therapy called dialectical behavior therapy (DBT) adapted to help people with emotional disorders like depression or anxiety. It aims to improve emotional regulation and reduce symptoms.
TaipeiAges 18–65 - NCT06032377Recruiting
Online therapy for sleep and brain health in older adults
This study tests an online talk therapy program (CBT) to help older adults with both sleep troubles and mild memory or thinking concerns. It's done from home, and aims to improve sleep and brain health.
Ottawa, OntarioAges 60–99 - NCT06038409Recruiting
Ketamine therapy for chronic conditions
This trial tests if ketamine can help people with long-term health issues. It aims to find new treatments for chronic conditions that haven't responded well to other therapies.
Helena, MontanaAges 18 years+ - NCT06038721Recruiting
Unified Protocol for kids with emotional concerns
This trial tests a program called Unified Protocol for children ages 7–17 who have emotional difficulties like anxiety, depression, trauma, or obsessive-compulsive symptoms. It aims to help kids and their parents learn skills to manage these feelings together.
Coral Gables, FloridaAges 7–17 - NCT06116812Recruiting
Laughter yoga and stress reduction for women with breast cancer
This study tests if laughter yoga or mindfulness-based stress reduction helps women with early-stage breast cancer feel less anxious and depressed during chemotherapy. You would join online group sessions from home using your smartphone.
İskenderun, HatayAges 18–60 - NCT06118606Recruiting
Team program for ICU survivors at risk of problems
This study tests a team-based program to help ICU survivors who are at risk for physical or emotional problems after their stay. The goal is to see if this extra support can improve recovery.
StockholmAges 18 years+ - NCT06136676Recruiting
Comparing spiritual and secular meditation in healthy adults
This study looks at how two kinds of meditation—spiritual (Christian or Muslim) and secular (non-religious)—affect your mind, body, emotions, and social life. If you are a healthy Christian or Muslim adult who prays weekly, this could help researchers understand which type of meditation may work best for people like you.
Calicut, KeralaAges 18–60 - NCT06187090Recruiting
Supplement therapy for adults with autism
This trial tests whether a specific supplement can help adults with Level 1 autism. It is open only to Italian-speaking participants aged 18–35 who do not have other major mental health or brain conditions.
Udine, UDAges 18–35 - NCT06218121Recruiting
Frailty detection trial for older adults
This trial aims to improve how frailty is detected in older adults. It tests a new approach to identify frailty early, which could help prevent health problems.
Madrid, Outside of the USAges 62 years+ - NCT06246214Recruiting
Biological rhythms for perinatal mental health
This study looks at whether understanding your body's daily rhythms (like sleep and activity) can help treat depression after childbirth. If you are 4-6 weeks postpartum and have been diagnosed with postnatal depression, this could be an option for you.
Porto Alegre, Rio Grande do SulAges 18 years+ - NCT06273527RecruitingPhase 2/Phase 3
Thinking skills training for mood and anxiety
This study tests whether a computerized training program can help people with mood, anxiety, or trauma-related disorders who struggle with repetitive negative thinking. If you are an outpatient and can have an MRI, this may be a good fit.
San Diego, CaliforniaAges 21–55 - NCT06277661Recruiting
Mom and Infant Outcomes Study
This study tests a program to support pregnant people who have had high blood pressure, diabetes, or depression/anxiety. It aims to improve outcomes for both mothers and babies.
Columbus, OhioAges Any age - NCT06300255Recruiting
Evaluation of the H.O.O.V.E.S. Healing Program
This study looks at a program called H.O.O.V.E.S. Healing Intensives for veterans. It aims to understand how the program helps participants.
Salt Lake City, UtahAges 18–120 - NCT06324864Recruiting
START NOW Adapted for migrant teens, ages 14-18
This trial tests a culturally adapted version of a program called START NOW. It's designed to help teenagers who are migrants in Switzerland and are feeling depressed or very stressed learn new skills to feel better.
Basel, Canton of Basel-CityAges 14–18 - NCT06350201Recruiting
Online CBT Based on Symptom Groups
This study uses a computer program to group symptoms and then offers an online cognitive behavioral therapy (CBT) program. It aims to help people who feel depressed or anxious by tailoring treatment based on their specific symptom patterns.
WuhanAges 18–64 - NCT06363019Recruiting
Support for at-risk mothers during pregnancy
This study offers support for mothers who are going through a tough time during pregnancy or after birth. It is designed to help women who may be financially stressed, single, or dealing with emotional challenges.
SingaporeAges 21–65 - NCT06442774Recruiting
Mamaconecta: app support for moms' mental health
This study tests a digital tool called MamaConecta to support mothers' mental health during pregnancy. If you are between 12 and 14 weeks pregnant, speak Spanish, and have a smartphone, you may be able to join.
Barcelona, CataloniaAges 18 years+ - NCT06512025Recruiting
Education program for first-time new mothers
This study tests whether a short education program (psychoeducational intervention) can help new first-time moms feel more confident and supported after childbirth. If you qualify, you would receive extra information and guidance during your postpartum checkups.
Barcelona, BarcelonaAges 18 years+ - NCT06521398Recruiting
Postpartum Care for Preterm NICU Babies
This study focuses on helping new mothers of preterm babies (born before 34 weeks) who are getting care in the NICU at HUP. It tests a program to support your transition home after giving birth, so you and your baby can thrive.
Philadelphia, PennsylvaniaAges 16 years+
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Common questions
- Are there clinical trials for depression, anxiety?
- Yes. Clin2 currently lists 479 recruiting depression, anxiety studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a depression, anxiety trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a depression, anxiety trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.