Clinical trials
Depression, Anxiety clinical trials
Below are recruiting depression, anxiety clinical trials, each written for real people, not researchers. We’re tracking 479 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07055061Recruiting
Music for reducing stress, anxiety and depression
This trial tests if listening to specially designed music can help reduce stress, anxiety and depression. It may be a good option for people who are not currently taking medication or receiving treatment.
Beijing, Beijing MunicipalityAges 18–60 - NCT06188923RecruitingPhase 2
Pregnenolone for anxiety and depression in veterans
This trial tests whether a dietary supplement called pregnenolone can help veterans with anxiety and depression feel better and function better. It's a new approach that may be added to your current treatment.
Durham, North CarolinaAges 18–65 - NCT06517589Recruiting
A new talk therapy for hard-to-treat anxiety and depression
This study tests a new type of talk therapy called 'process-based therapy' for people whose anxiety or depression has not gotten better with at least two prior treatments. The goal is to see if this approach can help when standard treatments have not worked.
Frankfurt am Main, HesseAges 18–65 - NCT06833567Recruiting
Mentalizing therapy for anxiety and depression
This study tests a group therapy that helps people understand their own and others' thoughts and feelings. It may help if you have anxiety or depression and can talk in a group setting.
Málaga, MalagaAges 18 years+ - NCT06844058Recruiting
Religious vs. standard hypnosis for anxiety and depression
This study compares two types of hypnosis (one that includes Islamic themes and one that follows a standard approach) to see which works better for anxiety and depression. It is designed for Muslim adults who are feeling stressed but do not have a formal mental health diagnosis.
IstanbulAges 18–65 - NCT06853587Recruiting
Genetic test to help pick antidepressant for teens
This study tests whether using a cheek swab DNA test can help choose a better antidepressant for teenagers with anxiety or depression. The goal is to see if this personalized approach leads to fewer side effects and better results.
Calgary, AlbertaAges 12–17 - NCT07112001Recruiting
Mobile app for anxiety and depression in HIV
This study tests a mobile health program to help people with HIV manage symptoms of anxiety and depression. It is designed to offer support through your phone and may improve your mood and overall health.
Gainesville, FloridaAges 18–90 - NCT07432815RecruitingPhase 4
Psoriasis with depression: methotrexate plus an antidepressant
This trial tests if adding an antidepressant (escitalopram) to standard methotrexate treatment works better than methotrexate alone for people who have both psoriasis and depression or anxiety. If you have moderate to severe psoriasis and also struggle with depression or anxiety, this study might offer a way to treat both conditions together.
Cairo, Cairo GovernorateAges 18–60 - NCT05589337Recruiting
Baduanjin exercise program for depression and anxiety symptoms
This study tests whether practicing Baduanjin (a gentle movement/exercise) can reduce symptoms of depression and anxiety. It may help people who are able to follow instructions and communicate clearly.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT06923995Recruiting
AI-based depression and anxiety assessment study
This study tests an AI tool that analyzes video and audio recordings to measure depression and anxiety. It is for people starting a new treatment for depression or anxiety and aims to see if the AI can accurately track their progress.
Houston, TexasAges 18–65 - NCT05671419Recruiting
Mindful self-compassion training for anxiety and depression
This study tests whether a structured “mindful self-compassion” program can reduce symptoms of anxiety disorders or depression. It’s meant to help by improving how you relate to yourself during difficult thoughts and feelings.
Washington D.C., District of ColumbiaAges 18–75 - NCT06456307Recruiting
Stepped care for mood and anxiety during pregnancy
This study tests a step-by-step approach to help pregnant women who are feeling anxious or down. If you are at least 28 weeks pregnant and feeling stressed, worried, or sad, the study will offer you support and check on how you are doing.
NairobiAges 14 years+ - NCT06881758Enrolling by invitation
High intensity training for anxiety treatment
This study tests whether high intensity exercise can help reduce anxiety symptoms. It is for adults with mild to moderate anxiety disorders who are physically able to exercise.
TromsøAges 18–65 - NCT07476469Recruiting
Nerve stimulation for anhedonia and anxiety
This study tests whether a gentle nerve stimulation device (tVNS) placed on your ear can help reduce symptoms of anhedonia (loss of pleasure) and anxiety. You will also have brain scans (MRI) to see how the treatment affects your brain.
BonnAges 18–40 - NCT06892847Recruiting
Brain stimulation for anxiety and depression in youth
This study tests if a non-invasive brain stimulation technique called TMS can help reduce symptoms of anxiety or depression in children and teens. It involves sessions where a magnetic field is used to gently stimulate parts of the brain, and is designed for young people aged 6 to 18 who have been diagnosed with these conditions.
Calgary, AlbertaAges 6–18 - NCT05559749Recruiting
Support program for anxiety and depression in people with epilepsy
This study tests a “collaborative care” program to help reduce anxiety and depression symptoms in adults with epilepsy. You would answer questionnaires and work with a care team, and the study is designed to see how well this approach can help over time.
Winston-Salem, North CarolinaAges 18 years+ - NCT07532551Recruiting
Online Therapy for Anxiety and Depression in Singapore
This study tests an internet-based cognitive behavioral therapy (a self-guided online mental health program) for people with mild-to-moderate anxiety or depression. You'd use an app on your phone or computer to work through lessons and exercises designed to help manage these feelings.
SingaporeAges 21 years+ - NCT07180537Recruiting
Health course for joint and mood conditions
This study tests an online health course that helps improve diet and self-care to support cell health and wellbeing. It is for people with certain rheumatological conditions like rheumatoid arthritis, lupus, or psoriatic arthritis, who also have mood concerns.
Iowa City, IowaAges 18–100 - NCT06881693Recruiting
Online CBT for depression and anxiety in new parents
This study tests an internet-based cognitive behavioral therapy (CBT) program for parents who are expecting or have a new baby (up to 2 years old) and are struggling with depression or anxiety. It's designed to help you learn skills you can use at home, on your own schedule.
Regina, SaskatchewanAges 18 years+ - NCT07469462Recruiting
High-dose vitamin B6 for depression and anxiety
This study tests whether high doses of vitamin B6 can help reduce symptoms of anxiety and depression. If you have mild to moderate anxiety or depression, you may be able to participate.
Reading, EnglandAges 18–41 - NCT04014829Recruiting
Study of pain processing after planned hysterectomy
This trial looks at how the nervous system and fear of pain may affect pain after a planned hysterectomy. If you qualify, you may be asked about pain levels and pain sensitivity to better understand who may have more pain recovery challenges.
SingaporeAges 21–80 - NCT06610552Recruiting
Powerly: Preventing depression and anxiety after childbirth
This trial tests a science-based smartphone program to help prevent postpartum depression and anxiety. It is designed for pregnant women who are between 24 and 32 weeks along and have an iPhone.
ZurichAges 18 years+ - NCT06651801Recruiting
Group therapy for anxiety or depression
This trial tests whether a virtual group therapy program is a good way to help people in Manitoba with anxiety or depression. If you're looking for support and can join a small online group, this might be a helpful option.
Winnipeg, ManitobaAges 18 years+ - NCT06628830Enrolling by invitation
App for depression and anxiety in college students
This trial tests if a mobile phone app can help college students with mild to moderate depression and anxiety. You may be eligible if you are a student with moderate symptoms and not currently in treatment.
Santiago, Santiago MetropolitanAges 18–29
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Common questions
- Are there clinical trials for depression, anxiety?
- Yes. Clin2 currently lists 479 recruiting depression, anxiety studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a depression, anxiety trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a depression, anxiety trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.