Clinical trials
Depression, Anxiety clinical trials
Below are recruiting depression, anxiety clinical trials, each written for real people, not researchers. We’re tracking 479 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06358495Recruiting
Sleep improvement to prevent depression and anxiety in teens
This study tests if improving sleep can help prevent depression and anxiety in teens who are at higher risk because a parent has had depression or anxiety. It's for teens who have trouble sleeping but don't have a history of depression or anxiety themselves.
Calgary, AlbertaAges 12–18 - NCT06801041RecruitingPhase 2
Psilocybin therapy for anxiety or depression in cancer survivors
This trial tests if a single dose of psilocybin, given with therapy, can help cancer survivors who struggle with anxiety or depression. You would travel to MD Anderson for treatment and follow-up, and must stop certain medications beforehand.
Houston, TexasAges 18 years+ - NCT07182890RecruitingPhase 4
Probiotic for anxiety and depression in functional dyspepsia
This trial tests whether a probiotic called Clostridium Butyricum can help reduce anxiety and depression in people with functional dyspepsia (a type of stomach discomfort without a clear cause). If you have mild to moderate anxiety or depression along with your stomach symptoms, this study may offer a potential new treatment option.
Xi’an, ShanxiAges 18–80 - NCT07187492RecruitingPhase 4
Can a probiotic ease anxiety and depression in functional dyspepsia?
This trial tests whether a probiotic called Bacillus coagulans can help reduce anxiety and depression in people with functional dyspepsia, a condition that causes stomach pain or discomfort without a clear physical cause. You may qualify if you have mild to moderate anxiety or depression alongside your stomach symptoms.
Xi’an, ShanxiAges 18–80 - NCT06078007Recruiting
App for depression and anxiety in college students
This trial tests if a guided mobile app can help college students with mild to moderate depression or anxiety. You might benefit if you are not currently receiving mental health treatment and have a smartphone.
Palma de Mallorca, Balearic IslandsAges 18 years+ - NCT07544563Recruiting
Brain Activity During Sound Testing
This study measures how your brain responds to sounds in a specially designed quiet room. Researchers want to understand how epilepsy affects sound processing, which could help improve treatment in the future.
ParisAges 18 years+ - NCT07590115Enrolling by invitation
Behavioral Patterns and Treatment Success in Substance Use Recovery
This study looks at how behavioral patterns change during residential treatment for substance use disorder. Researchers will track your progress over several weeks to understand what helps people succeed in recovery.
Potrerillos, JaliscoAges 18–60 - NCT05570812RecruitingPhase 2
Pregnenolone to improve depressed mood in people with HIV
This Phase 2 trial tests a brain-acting steroid called pregnenolone to help reduce depressed mood. It studies whether it can improve mood in adults with HIV who are already on HIV treatment and still have depression symptoms.
Boston, MassachusettsAges 18–85 - NCT07646834Recruiting
Brain-Gut Study of IBS with Anxiety and Depression
This study explores how stress and mood changes affect irritable bowel syndrome (IBS) using brain imaging. Researchers will scan your brain and collect health information to understand the connection between your gut and mental health.
Xi'an, ShaanxiAges 18–60 - NCT05855421Recruiting
Ear acupuncture sessions for moderate depression during COVID
This trial tests whether auricular (ear) acupuncture can safely improve symptoms of moderate depression during the COVID period. You may be able to join if you’re an adult with moderate depression and can attend the study sessions.
Palhoça, Santa CatarinaAges 18–50 - NCT06449547Recruiting
Risk factors for anxiety and depression in shingles nerve pain
This study looks at what makes people with shingles nerve pain more likely to feel anxious or depressed. By joining, you'll help doctors understand how to better support patients like you.
Wuhan, HubeiAges 18 years+ - NCT07653035Recruiting
Can a weighted blanket help with anxiety during cancer treatment?
This study tests whether using a weighted blanket during intravenous cancer therapy (like chemo or immunotherapy) can reduce anxiety, stress, and depression, and increase comfort. It also checks if nurses find it easy to use.
Muscat, SeebAges 18 years+ - NCT05637320Recruiting
Therapy study for children’s big emotions and mood
This study looks at how children’s emotions change during therapy for concerns like anxiety, depression, or disruptive behavior. It may help you and your child understand what kinds of therapy support might work best.
Guelph, OntarioAges 8–15 - NCT06997549Recruiting
Review of mental health treatment outcomes
This study looks back at information from a large database of people who received mental health treatments. It aims to understand how well treatments worked and what factors influenced outcomes.
Malvern, PennsylvaniaAges 5–100 - NCT06899308Recruiting
Health check for university students
This study checks the health of students at two universities in Germany. It uses online surveys and interviews to monitor well-being over time.
BremenAges 18 years+ - NCT07168096Recruiting
Emotional health and decision-making in cancer patients
This study tracks how anxiety and depression change over time in people with solid tumors. It aims to find risk factors and improve supportive care, while also exploring how much patients understand about their prognosis and want to be involved in decisions.
Santander, CantabriaAges 18 years+ - NCT07363980Enrolling by invitation
Heart CT Study for Rheumatoid Arthritis Patients
This study uses a special heart CT scan to look for early signs of heart disease in people with rheumatoid arthritis. It may help find problems before symptoms start.
AarhusAges 50–75 - NCT04478305RecruitingPhase 1
Duavive trial for mood and anxiety in midlife women
This Phase 1 study tests Duavive’s effects on mood and anxiety symptoms in women going through perimenopause or early menopause. It may help clarify whether this treatment can reduce depression and/or anxiety symptoms in midlife.
Hamilton, OntarioAges 45–60 - NCT06269146RecruitingPhase 2
Pramipexole to improve social connections
This study tests if a medication called pramipexole can help people with anxiety or depression who also find it difficult to connect socially. It looks at whether the drug can improve your motivation for social interactions and help you feel more connected.
San Diego, CaliforniaAges 18–50 - NCT07007234Recruiting
Sedentary behavior and depression study
This study looks at how sitting or being inactive (sedentary behavior) affects depressive symptoms. If you have mild to severe depression, you may be able to join and help find out if moving more can improve your mood.
São Paulo, SOAges 18 years+ - NCT07033741Recruiting
EMDR therapy for depression symptoms study
This trial studies whether EMDR therapy helps reduce depressive symptoms and what factors predict improvement. It is open to patients with anxiety, depression, PTSD, or dissociation symptoms.
Turin, TurinAges 18 years+ - NCT07129941Recruiting
Unified group therapy for anxiety and depression
This study tests a group therapy program for adults aged 18-40 with anxiety or depression. It aims to help people learn skills to manage their emotions and symptoms together in a supportive group setting at a university clinic.
Bergen, VestlandAges 18–40 - NCT07372586Recruiting
Behavioral health support after ICU stay
This study tests a collaborative care model for mental health and recovery after an ICU stay. You might qualify if you visit the MUSC ICU Recovery Clinic within six months of leaving the hospital.
Charleston, South CarolinaAges 18 years+ - NCT07390786Recruiting
Family support program after ICU stay
This study tests a collaborative care program for family members of ICU recovery patients, designed to improve mental health support after a loved one's hospitalization.
Charleston, South CarolinaAges 18 years+
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Common questions
- Are there clinical trials for depression, anxiety?
- Yes. Clin2 currently lists 479 recruiting depression, anxiety studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a depression, anxiety trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a depression, anxiety trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.