Clinical trials
Depression, Anxiety clinical trials
Below are recruiting depression, anxiety clinical trials, each written for real people, not researchers. We’re tracking 442 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05637320Recruiting
Therapy study for children’s big emotions and mood
This study looks at how children’s emotions change during therapy for concerns like anxiety, depression, or disruptive behavior. It may help you and your child understand what kinds of therapy support might work best.
Guelph, OntarioAges 8–15 - NCT06997549Recruiting
Review of mental health treatment outcomes
This study looks back at information from a large database of people who received mental health treatments. It aims to understand how well treatments worked and what factors influenced outcomes.
Malvern, PennsylvaniaAges 5–100 - NCT07168096Recruiting
Emotional health and decision-making in cancer patients
This study tracks how anxiety and depression change over time in people with solid tumors. It aims to find risk factors and improve supportive care, while also exploring how much patients understand about their prognosis and want to be involved in decisions.
Santander, CantabriaAges 18 years+ - NCT07363980Enrolling by invitation
Heart CT Study for Rheumatoid Arthritis Patients
This study uses a special heart CT scan to look for early signs of heart disease in people with rheumatoid arthritis. It may help find problems before symptoms start.
AarhusAges 50–75 - NCT04478305RecruitingPhase 1
Duavive trial for mood and anxiety in midlife women
This Phase 1 study tests Duavive’s effects on mood and anxiety symptoms in women going through perimenopause or early menopause. It may help clarify whether this treatment can reduce depression and/or anxiety symptoms in midlife.
Hamilton, OntarioAges 45–60 - NCT07390786Recruiting
Family support program after ICU stay
This study tests a collaborative care program for family members of ICU recovery patients, designed to improve mental health support after a loved one's hospitalization.
Charleston, South CarolinaAges 18 years+ - NCT07372586Recruiting
Behavioral health support after ICU stay
This study tests a collaborative care model for mental health and recovery after an ICU stay. You might qualify if you visit the MUSC ICU Recovery Clinic within six months of leaving the hospital.
Charleston, South CarolinaAges 18 years+ - NCT07129941Recruiting
Unified group therapy for anxiety and depression
This study tests a group therapy program for adults aged 18-40 with anxiety or depression. It aims to help people learn skills to manage their emotions and symptoms together in a supportive group setting at a university clinic.
Bergen, VestlandAges 18–40 - NCT07033741Recruiting
EMDR therapy for depression symptoms study
This trial studies whether EMDR therapy helps reduce depressive symptoms and what factors predict improvement. It is open to patients with anxiety, depression, PTSD, or dissociation symptoms.
Turin, TurinAges 18 years+ - NCT07007234Recruiting
Sedentary behavior and depression study
This study looks at how sitting or being inactive (sedentary behavior) affects depressive symptoms. If you have mild to severe depression, you may be able to join and help find out if moving more can improve your mood.
São Paulo, SOAges 18 years+ - NCT07458698Recruiting
A digital program to prevent anxiety during pregnancy
This study tests a mobile app called Reaching Calm that may help prevent anxiety disorders in pregnant people. It is for those who are already receiving prenatal care and have mild to moderate anxiety symptoms.
Leominster, MassachusettsAges 18 years+ - NCT07272213Recruiting
Thyroid hormone levels, mood, and sexual health in pregnancy
This study looks at how thyroid-stimulating hormone (TSH) levels during pregnancy are linked to depression, anxiety, and sexual function in pregnant women.
Istanbul, GaziosmanpaşaAges 18–45 - NCT06706323Recruiting
Depression after heart surgery study
This study looks at depressive symptoms in people who have had heart bypass surgery. It aims to understand how patients feel emotionally after surgery and may help improve care.
ZurichAges 18–90 - NCT06928428Enrolling by invitation
Online talk therapy for depression or anxiety
This study tests if a type of talk therapy called metacognitive therapy, delivered partly online, helps adults with depression or generalized anxiety. It aims to see if this blended approach works well in primary care.
Stockholm, Stockholm CountyAges 18 years+ - NCT06490315Enrolling by invitation
Studying OkeyMind for social anxiety in young people
This trial tests if a smartphone program called OkeyMind helps reduce social anxiety in young people aged 15-24. It also looks at whether the program is worth the cost.
Hong Kong, Hong KongAges 15–24 - NCT06212219Recruiting
EEG brain training to help arm recovery after stroke
This study tests whether a brain-training technique called neurofeedback can improve arm movement in people who recently had a stroke. It uses an EEG cap to measure your brain activity while you do arm exercises, helping you relearn how to move your affected arm.
ToulouseAges 18–99 - NCT07041073Recruiting
Brain training for emotion control in depression
This trial tests if a non-invasive brain training technique called neurofeedback can help people with major depression improve how they manage emotions. You participate by doing computer tasks while your brain activity is measured and shown back to you, teaching you to regulate your emotions better.
Sabadell, Barcelona, CataluñaAges 18–65 - NCT07717541Recruiting
Virtual poetry workshops for anxiety and stomach issues
This study tests if joining a facilitated online poetry workshop can help reduce anxiety and improve well-being for people with stomach discomfort. You would attend virtual group sessions and share poems you create.
Columbus, OhioAges 18 years+ - NCT06776887Recruiting
Virtual reality exercises for burn recovery on legs
This trial tests whether virtual reality exercises can help people with leg burns improve balance and reduce depression and anxiety. It is for people who had a large thermal burn on their lower body at least 3 months ago.
GizaAges 35–55 - NCT06660888Enrolling by invitation
Study of fatigue, depression, and anxiety in people with low thyroid
This study looks at how common fatigue, depression, and anxiety are in people with hypothyroidism (underactive thyroid). It aims to understand if these symptoms are linked to thyroid hormone levels.
Asyut, AssuitAges 18–60 - NCT07834684Recruiting
Singula health survey for routine primary care visits
This study tests a new survey during a regular doctor's visit to see if it helps improve care. If you join, you'll answer questions on your own device.
Brentwood, New YorkAges 18 years+ - NCT07639606Recruiting
Mobile therapy app for mood after recent stroke
This study tests whether using a smartphone or tablet app for cognitive behavioral therapy (a type of talk therapy you do on your device) can help with anxiety and depression in the first month after a stroke. The goal is to see if this convenient, at-home approach improves how you feel during early recovery.
New York, New YorkAges 18–79 - NCT06823492Recruiting
Early life and brain study
This study looks at how your early life experiences may affect your brain and behavior. You would visit the University of Manchester for assessments and help researchers understand these connections.
ManchesterAges 18–25 - NCT07383467Recruiting
Single session help for teens with anxiety or depression
This trial offers a one-time digital self-help program for Hong Kong teens aged 12 to 17 who feel anxious or down. It aims to see if a single session can make a difference.
Hong KongAges 12–17
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Common questions
- Are there clinical trials for depression, anxiety?
- Yes. Clin2 currently lists 442 recruiting depression, anxiety studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a depression, anxiety trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a depression, anxiety trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.