Clinical trials
Depression clinical trials
A common mood disorder causing persistent sadness and loss of interest. We’re tracking 1,419 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07101796Recruiting
Mood and personality in sleep apnea treatment
This study looks at how mood and personality traits affect treatment adherence in people with suspected or confirmed sleep apnea. It may help tailor support for better treatment outcomes.
Beijing, Beijing MunicipalityAges 18–70 - NCT07097545Recruiting
Social media, exercise, and mindfulness for college students
This study tests whether limiting social media to a few minutes daily and doing brief exercise or mindfulness activities for two weeks can improve well-being. It is for Johns Hopkins students who use social media a lot and currently exercise an hour or less each day.
Baltimore, MarylandAges 18 years+ - NCT07102147Recruiting
Telehealth Therapy for Lung Cancer Patients at Penn Medicine
This trial offers therapy sessions (via phone or video) for people with lung cancer who are dealing with depression, anxiety, or other emotional concerns. It's part of Penn Medicine's collaborative care program and aims to make mental health support easier to access while you are being treated for lung cancer.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07105111RecruitingPhase 4
Valbenazine for tardive dyskinesia after other treatment
This study tests if valbenazine helps adults with tardive dyskinesia whose symptoms continue even after taking or stopping another similar medication. Tardive dyskinesia involves uncontrollable movements from long-term use of certain mental health drugs.
Bryant, ArkansasAges 18 years+ - NCT07091032Recruiting
Building connections for better health
This study tests if helping people address obesity, cancer screenings, or mental health struggles can improve their overall health. You may qualify if you have obesity, are behind on colon or cervical cancer screening, or have depression or anxiety.
Boston, MassachusettsAges 18–75 - NCT07095205RecruitingPhase 4
Nicotine's effect on depression in brain imaging study
This trial uses a special brain scan to see how nicotine might help treat depression. It compares people with depression to healthy volunteers to understand how nicotine affects brain chemistry related to mood.
Stony Brook, New YorkAges 18–65 - NCT07095582Recruiting
Online therapy with extra tools for depression and anxiety
This study adds extra content to internet-based cognitive behavioral therapy to see if it helps people manage depression and anxiety better. You can participate from home if you live in Saskatchewan and are 18 or older.
Regina, SaskatchewanAges 18 years+ - NCT06975280Recruiting
PTSD therapy for unaccompanied refugee teens in Greece
This study tests a talking therapy (Trauma-Focused Cognitive Behavioral Therapy) to help unaccompanied refugee minors aged 15-18 who have PTSD or stress symptoms from trauma. It aims to see if the therapy reduces distress and helps them feel better.
AthensAges 15–18 - NCT07083037Recruiting
Parent program to help kids' attention and behavior
This trial tests a program for mothers who have mild to moderate depression and whose child has attention or behavior problems. The program aims to improve both the mother's well-being and the child's behavior.
Winnipeg, ManitobaAges 18 years+ - NCT07084454Enrolling by invitationPhase 3
Remote geriatric care for older adults starting cancer treatment
This trial tests whether remote health assessments and support can improve care for adults 65+ who are starting a new cancer treatment. You'd participate from home via telehealth visits.
Rio de Janeiro, Rio de JaneiroAges 65 years+ - NCT07076342RecruitingPhase 4
Glutamate receptors and cognitive behavioral therapy for insomnia
This study tests how a brain receptor called mGluR5 affects sleep and depression treatment. You may qualify if you have major depression with insomnia and are not currently on antidepressants.
Stony Brook, New YorkAges 18 years+ - NCT07083492Recruiting
Detecting iron deficiency in pregnancy and after birth
This study uses a non-invasive test to check for iron deficiency in women during pregnancy and up to 3 months after giving birth. It aims to make detection easier and more comfortable for you.
Würzburg, BavariaAges 18 years+ - NCT07082218Recruiting
Sleep program to help teens recover from concussion
This study tests whether a sleep-focused program can help teenagers recover from a concussion. If you have ongoing symptoms after a concussion, this program might improve your sleep and speed up recovery.
Aurora, ColoradoAges 10–19 - NCT07079930RecruitingPhase 1
Study on psilocybin and D-serine safety in healthy volunteers
This trial tests whether a combination of psilocybin and D-serine is safe and affects mood and thinking. It's for healthy people who want to help research on psychedelics.
JerusalemAges 25–60 - NCT05676918Recruiting
Postpartum well-being study for mothers in the past year
This study looks at mothers’ well-being after having a baby, to understand what affects mental and emotional health after childbirth. It may help improve support for mothers during the postnatal period.
Madrid, Pozuelo de AlarcónAges 18 years+ - NCT07073963Recruiting
Online groups for sarcoidosis fatigue
This trial tests whether virtual group sessions can help reduce fatigue related to sarcoidosis. You'll join a supportive online group with others who have similar symptoms.
Cleveland, OhioAges 18 years+ - NCT07066631Recruiting
Online mental health support for pregnant and new parents
This trial tests a virtual program to help pregnant people and new parents with depression or anxiety. It provides mental health support through online tools and care coordination.
Toronto, OntarioAges 18 years+ - NCT06928480Recruiting
Unified Protocol for Emotional Health in Long COVID
This study tests a program to help people with Long COVID manage emotional difficulties like depression or anxiety. It combines different therapy approaches into one treatment, which you can receive online from home.
Zaragoza, ZaragozaAges 18 years+ - NCT07060066Recruiting
TMS for depression in schizophrenia
This study tests whether a type of brain stimulation called TMS (transcranial magnetic stimulation) can help with depression in people who have schizophrenia. You would receive TMS sessions targeting areas of the brain linked to mood, and the goal is to see if this improves depression symptoms.
Houston, TexasAges 18–60 - NCT07055906Recruiting
Video coaching to help Latino families talk about race
This study tests a video-based coaching program to help Latino parents and their 10–14-year-old children talk about race and ethnic background. Families will be recorded having a conversation, then get feedback to strengthen their communication.
Harrisburg, PennsylvaniaAges 10–14 - NCT07062042Recruiting
Empowering narratives for Ukrainian refugees in Norway
This study tests a therapy program for Ukrainian refugees in Norway who have PTSD symptoms or have experienced trauma. It aims to help participants by exploring personal stories and coping strategies.
OsloAges 18 years+ - NCT07059234Recruiting
Depression and Activity: The MASE Project
This study tests whether tracking your daily activity can help improve energy and mood in people with depression. You will wear a small device that measures your movement.
BernAges 18–60 - NCT07048990Recruiting
Empowerment group therapy for Ukrainian adults affected by war
This trial tests a group therapy program designed to help Ukrainian adults cope with depression, anxiety, stress, or other war-related distress. It aims to see if this support is helpful and practical for people living in or from Ukraine.
Kyiv, Kyiv OblastAges 18 years+ - NCT07052110Recruiting
Depression and self-esteem help for teen cancer survivors
This study tests a program called DST to see if it can reduce depression, boost self-esteem, and improve quality of life for teenagers who have finished cancer treatment.
Hong KongAges 13–18
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Common questions
- Are there clinical trials for depression?
- Yes. Clin2 currently lists 1,419 recruiting depression studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a depression trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a depression trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.