Clinical trials
Depression clinical trials
A common mood disorder causing persistent sadness and loss of interest. We’re tracking 1,419 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07167849Recruiting
Digital help while waiting for therapy
This trial tests a brief digital program for people waiting for outpatient therapy. It aims to provide support during the wait and see if it helps improve mental health symptoms.
BernAges 18 years+ - NCT07165925Recruiting
Music lessons to build resilience in children from low-income families
This study tests whether music training can help build emotional strength in children aged 8-12 from low-income families in Hong Kong. It specifically looks at children who may be at risk for depression or anxiety.
Hong KongAges 8–12 - NCT06462638Recruiting
Contact and relationship in the NICU for preterm babies
This study looks at how contact and relationship-building between parents and their babies in the neonatal intensive care unit (NICU) can help. It is for babies born a bit early (33–36 weeks) who are now stable, and for their parents under 50.
MessinaAges 18–50 - NCT07160673Recruiting
Tech-based caregiver break for homebound older adults
This study is testing if a virtual reality (VR) headset or video interaction can give caregivers a short break while the older adult they care for stays safe at home. It aims to reduce caregiver stress and improve well-being for both of you.
Hong Kong, 香港島Ages 18 years+ - NCT07155941Recruiting
App-based training for lack of pleasure
This trial tests if an app-based training program can help people who have trouble feeling pleasure from daily activities (anhedonia). It combines mood check-ins and simple, repeated exercises to retrain the brain's reward system.
Marburg, HesseAges 18 years+ - NCT07149428Recruiting
Deep study of smell loss causes using brain scans
This study uses brain imaging and electrical recordings to understand the brain's role in smell loss from any cause—like COVID, sinus problems, or chemotherapy. You may be eligible if you have any degree of smell loss lasting under a year.
Bethesda, MarylandAges 18–99 - NCT07151573Recruiting
Big five intervention trial for mental health in Norway
This trial tests a program called the Big Five Intervention to help people with anxiety or depression symptoms. It is available for people living in Norway who are 16 or older.
Bergen, VestlandAges 16 years+ - NCT07152925Recruiting
Brain stimulation for impulse control in teens with self-injury
This trial tests whether a gentle electrical current applied to the scalp can improve impulse control in adolescents who harm themselves without wanting to die. The goal is to see if this non-invasive treatment can help reduce self-injury urges.
Hefei, AnhuiAges 12–22 - NCT07151079Recruiting
Group therapy for trans teens feeling stressed
This study tests a group therapy program for teens who are trans or gender diverse and feeling stressed, anxious, or sad. The goal is to see if talking together in a group helps improve their well-being.
Parkville, VictoriaAges 12–17 - NCT07138664Recruiting
Mental health program for teens in Malaysia
This trial tests a program to help young teenagers in Malaysia who are experiencing anxiety or depression. The program aims to improve mental health and well-being.
Kota Kinabalu, SabahAges 12–14 - NCT07143539Recruiting
Early exercise rehab after hospital stay for pulmonary embolism
This study tests if starting a supervised exercise program early after a hospital stay for a blood clot in the lungs (pulmonary embolism) helps patients recover better and feel less breathless. It is for people at higher risk of ongoing symptoms after their clot.
AarauAges 18 years+ - NCT07143357Recruiting
Recovering together: support for cardiac arrest survivors and caregivers
This study tests a mind-body program to help cardiac arrest survivors and their caregivers cope with emotional distress after the event. It combines in-person and video sessions to improve well-being together.
Boston, MassachusettsAges 18 years+ - NCT06777758RecruitingPhase 4
Comparing two sedatives for endoscopy procedures
This trial compares two sedative medications, Remimazolam and Propofol, to see which works better for upper GI endoscopy exams and treatments. The goal is to help doctors choose the best option for patients.
Kaohsiung CityAges 20–80 - NCT07129070Recruiting
Just-in-Time Training for Youth Mentors
This trial tests a new training program for mentors working with middle and high school students. It aims to help mentors better support youth who may be experiencing depression.
Minneapolis, MinnesotaAges 12 years+ - NCT06917950RecruitingPhase 1/Phase 2
Roxadustat for bone and brain health in dialysis patients
This study tests whether roxadustat, a medicine for anemia, can also help with bone problems and mood or thinking issues in people on hemodialysis.
Al Mansurah, DakahliyaAges 18 years+ - NCT07120711Recruiting
Sleep apnea, thinking, and mood study for kids and adults
This study looks at how sleep apnea affects thinking and mood by checking certain proteins in the body. They want to see if these proteins can help predict or explain changes in memory, focus, or emotions.
ShanghaiAges 5 years+ - NCT07107906Recruiting
CONNECT program: group telehealth to reduce loneliness in adults 55+
This trial tests a group-based telehealth program called CONNECT, which aims to reduce loneliness, social isolation, and mental health symptoms like anxiety or depression in adults aged 55 and older. You'll join online group sessions instead of in-person programs, making it easier to connect from home.
Winnipeg, ManitobaAges 55 years+ - NCT07115628Recruiting
Accelerated TMS for treatment-resistant depression
This trial tests an accelerated form of transcranial magnetic stimulation (TMS) for people with treatment-resistant depression who have been referred for ECT. It aims to offer a non-invasive, less intensive alternative with fewer side effects.
Jette, Brussels CapitalAges 18–70 - NCT07113665RecruitingPhase 1
Focused ultrasound brain treatment for severe anorexia
This trial tests if focused ultrasound can help people with severe anorexia nervosa who also have obsessive-compulsive disorder or major depression. It is for those who have not gotten better with other treatments.
Toronto, OntarioAges 18–65 - NCT07111169Recruiting
Brain stimulation and attention in depression study
This study tests whether a non-invasive brain stimulation technique (called iTBS) can improve attention problems in people with major depression. If you have depression and trouble focusing, this trial might help understand a new treatment option.
Chengdu, SichuanAges 18–55 - NCT06772194Recruiting
Taiwan Recovery After Stroke Study
This study looks at how people recover after a stroke. Researchers will check your thinking, memory, and daily function over a year to learn more about recovery patterns and help design better treatments.
TaipeiAges 18 years+ - NCT01980147Recruiting
Skills for Wellness program for youth coping with mental health risks
This trial tests a structured skills program to help children and teens (ages 9–21) cope with early mental health warning signs such as anxiety, mood swings, or unusual thoughts. It may help participants build practical coping tools and well-being.
Halifax, Nova ScotiaAges 9–21 - NCT03601026Recruiting
Genetic counseling for youth using cannabis safely
This study offers genetic counseling to help reduce mental health problems that can happen for some young people who use cannabis. You join if you are already part of the FORBOW study and fit their age and mental-health criteria.
Halifax, Nova ScotiaAges 12–21 - NCT07100951Recruiting
Comparing two couples therapies for relationship distress
This study compares two types of couples therapy to see which is better at reducing relationship distress. If you and your partner are feeling unhappy or struggling, and either of you also has symptoms of depression or anxiety, this trial may offer free professional help.
IstanbulAges 24–65
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Common questions
- Are there clinical trials for depression?
- Yes. Clin2 currently lists 1,419 recruiting depression studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a depression trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a depression trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.