Clinical trials
Diabetes (Insulin-requiring, Type 1 or Type 2) clinical trials
Below are recruiting diabetes (insulin-requiring, type 1 or type 2) clinical trials, each written for real people, not researchers. We’re tracking 2,193 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07754461RecruitingPhase 3
Survodutide for blood sugar control in type 2 diabetes
This study tests an investigational drug called survodutide to see if it helps people with type 2 diabetes manage their blood sugar levels. Participants will receive either survodutide or a placebo, and the study will compare changes in HbA1c (a measure of blood sugar control).
Birmingham, AlabamaAges 18 years+ - NCT07064473RecruitingPhase 3
Testing vicadrostat plus empagliflozin for diabetes, high blood pressure, and heart disease
This study tests a new pill called vicadrostat taken with another medicine (empagliflozin) to see if it helps people with type 2 diabetes, high blood pressure, and heart disease. It may reduce the risk of heart problems, but you must not have had heart failure or use certain other heart medications.
Anniston, AlabamaAges 18 years+ - NCT07563699RecruitingPhase 1/Phase 2
Long-acting semaglutide injection for type 2 diabetes
This study tests a new long-acting form of semaglutide (a diabetes medication you may already take weekly) given as a depot injection. Researchers want to see if this new form is safe and works better for managing type 2 diabetes.
Tel AvivAges 18–64 - NCT07770204Recruiting
Music during surgery for people with type 2 diabetes
This study tests whether listening to calming music before and during surgery can help reduce stress and improve recovery for people with type 2 diabetes. If you are scheduled for elective surgery and have type 2 diabetes, you may be able to join.
Istanbul, IstanbulAges 40–70 - NCT05762107RecruitingPhase 2
Drug ZT-01 to reduce low blood sugar at night
This Phase 2 study tests ZT-01 to help prevent night-time low blood sugar (hypoglycemia) in people with type 1 diabetes. It may help if you’ve had low blood sugar during sleep or are at high risk based on recent glucose monitoring.
Birmingham, AlabamaAges 18–75 - NCT07771010RecruitingPhase 4
Comparing empagliflozin and metformin for muscle health in type 2 diabetes
This study tests two diabetes medications, empagliflozin and metformin, to see how they affect muscle energy use and blood flow in men with recently diagnosed type 2 diabetes. Participants will be followed at a diabetes clinic.
LjubljanaAges 18–75 - NCT07448974RecruitingPhase 3
Vitamin D for Preventing Type 2 Diabetes
This study tests if taking extra vitamin D can help people with prediabetes keep their blood sugar in a healthy range and lower the chance of developing type 2 diabetes. Participants will take high-dose or standard vitamin D and be monitored for about 2 years.
Boston, MassachusettsAges 30–74 - NCT07731399Recruiting
Diabetes Study for Medicaid Members in South Carolina
This study collects blood samples and health information from people with type 2 diabetes and healthy controls to learn more about diabetes. It may help improve future care for diabetes.
Orangeburg, South CarolinaAges 40–70 - NCT07149610Recruiting
Connected care for type 2 diabetes self-management
This study tests a connected care program to help people with type 2 diabetes manage their condition better using a smartphone. It may help you if your blood sugar is not well controlled and you live in the Marche region of Italy.
Ancona, AnconaAges 18 years+ - NCT07767331Recruiting
Patient-reported outcomes for type 2 diabetes
This trial asks people with type 2 diabetes to fill out a questionnaire about their health and daily life. The answers help doctors in general practice provide better care.
AarhusAges 18 years+ - NCT07527650RecruitingPhase 2
Testing HM15275 for Type 2 Diabetes Management
This study tests a new medication called HM15275 to help control blood sugar in people with type 2 diabetes. The trial will check if the medication works well and is safe when added to diet, exercise, or metformin treatment.
Mesa, ArizonaAges 18–75 - NCT07674979Enrolling by invitation
Produce prescription for type 2 diabetes and food insecurity
This study tests whether giving people with type 2 diabetes free produce vouchers can improve blood sugar control and heart health. It is for patients who have trouble affording enough food and have high blood sugar levels.
Morgantown, West VirginiaAges 18 years+ - NCT07743450RecruitingPhase 3
Once-daily pill for weight loss in people with type 2 diabetes
This study tests an oral medication, ASC30, to see if it helps people with type 2 diabetes who are overweight or obese lose weight and improve blood sugar control. It is a once-daily pill that may offer a new treatment option.
Birmingham, AlabamaAges 18 years+ - NCT07351058RecruitingPhase 3
Enicepatide for weight loss in people with type 2 diabetes
This trial tests an investigational medication, Enicepatide, to see if it helps people with obesity or overweight and type 2 diabetes lose weight and improve blood sugar control. You will receive weekly injections and regular check-ups.
Guntersville, AlabamaAges 18 years+ - NCT07670416RecruitingPhase 3
A study of enicepatide for people with obesity or overweight
This trial tests if enicepatide can help people with obesity or overweight lose weight, including those with or without type 2 diabetes. It aims to see if the drug is safe and effective.
Zhengzhou, HenanAges 18 years+ - NCT06896799Recruiting
Food order and blood sugar in gestational diabetes
This study looks at whether the order in which you eat foods during a meal can help control your blood sugar levels. It might help you manage your gestational diabetes better through diet alone.
BelfastAges 18–50 - NCT05478707RecruitingPhase 2
Treating small blood vessel problems in type 1 diabetes
This study tests whether two different treatment strategies can improve the function of the tiny blood vessels in people with type 1 diabetes. It aims to find a way to prevent or reduce diabetes-related complications.
Orlando, FloridaAges 18–40 - NCT06993454Recruiting
Exercise and blood sugar in type 2 diabetes with fatty liver
This study looks at how a single session of exercise affects the body's natural sugar production in people with type 2 diabetes and fatty liver. It may help us find better ways to control blood sugar and treat fatty liver.
Orlando, FloridaAges 25–55 - NCT07757308Recruiting
Brain and heart connection in type 2 diabetes
This study looks at how type 2 diabetes affects the link between your brain and heart. Participants will undergo tests of memory, thinking, and heart function to see how these are related in diabetes.
TunceliAges 40–75 - NCT06830096Recruiting
Understanding a key cell channel in type 2 diabetes
This study looks at how a specific channel in your cells (called the KATP channel) affects blood sugar control in people with and without type 2 diabetes. It aims to understand why some people develop diabetes and how to better treat it.
St Louis, MissouriAges 18–65 - NCT06820281RecruitingPhase 2
Tirzepatide for type 1 diabetes: a metabolism study
This study tests if tirzepatide, a medicine that helps lower blood sugar and manage weight, is safe and effective for people with type 1 diabetes who are overweight or have obesity. You must already use an automated insulin pump system.
Sydney, New South WalesAges 18–65 - NCT07668388RecruitingPhase 2
Testing different doses of UBT251 for type 2 diabetes
This trial tests a new medicine, UBT251, to see how well it lowers blood sugar in people with type 2 diabetes. It compares different doses to find the best one for you.
Birmingham, AlabamaAges 18–75 - NCT06196996Recruiting
Donor islet transplant for brittle type 1 diabetes
This study tests a one-time transplant of insulin-making cells from a donor to treat brittle type 1 diabetes—a condition where blood sugar swings wildly and dangerously low. The goal is to help people who still have severe low blood sugar episodes despite intensive insulin therapy.
Shanghai, Shanghai MunicipalityAges 6–65 - NCT06888050RecruitingPhase 4
Study of new diabetes pill versus metformin for new type 2 diabetes
This trial tests a new combination pill (henagliflozin and metformin) compared to metformin alone in people recently diagnosed with type 2 diabetes. The goal is to see which treatment works better and is safer.
Hangzhou, ZhejiangAges 18–75
Hear when a new Diabetes (Insulin-requiring, Type 1 or Type 2) trial opens
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Common questions
- Are there clinical trials for diabetes (insulin-requiring, type 1 or type 2)?
- Yes. Clin2 currently lists 2,193 recruiting diabetes (insulin-requiring, type 1 or type 2) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a diabetes (insulin-requiring, type 1 or type 2) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a diabetes (insulin-requiring, type 1 or type 2) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.