Clinical trials
Diabetes (Insulin-requiring, Type 1 or Type 2) clinical trials
Below are recruiting diabetes (insulin-requiring, type 1 or type 2) clinical trials, each written for real people, not researchers. We’re tracking 2,155 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06482944Recruiting
Whole-food diet program for families to prevent type 2 diabetes
This 12-week program helps parents with prediabetes and their children eat healthier whole foods based on U.S. dietary guidelines. The goal is to see if the program can lower the risk of developing type 2 diabetes in the family.
Nashville, TennesseeAges 6–59 - NCT06474598RecruitingPhase 2
Test of MTX228 for type 1 diabetes with some insulin
This study tests a new medication, MTX228, to see if it can help people with type 1 diabetes who still make some insulin. It may slow the loss of your own insulin production and improve blood sugar control.
Edmonton, AlbertaAges 18–65 - NCT06455319RecruitingPhase 2
Personalized ATG with or without verapamil for new type 1 diabetes
This trial tests a new way to give a medicine called anti-thymocyte globulin (ATG) with or without verapamil, a blood pressure drug. It aims to slow down the loss of insulin-making cells in people newly diagnosed with type 1 diabetes.
Aurora, ColoradoAges 6–35 - NCT06402747RecruitingPhase 4
Comparing clopidogrel vs cilostazol for diabetes-related artery thickening
This trial compares two blood-thinning drugs (clopidogrel and cilostazol) to see which one better prevents artery problems in people with diabetes and thickened carotid arteries. It may help you if you have diabetes and are already on stable medications.
Seongnam-si, Gyeonggi-doAges 19 years+ - NCT06399835RecruitingPhase 4
Comparing two diabetes drugs for blood sugar and heart health
This study tests a new diabetes medicine called Enavogliflozin against an older drug, Pioglitazone, to see which works better for lowering blood sugar and improving heart health. If you have type 2 diabetes, take metformin plus another pill, and your A1C is between 7 and 10.5, this study may be an option for you.
Seongnam-si, Gyeonggi-doAges 20–80 - NCT06256419Recruiting
Gene testing and exenatide response in Chinese type 2 diabetes patients
This study looks at how certain genes affect the risk of type 2 diabetes and how well the drug exenatide (a GLP-1 receptor agonist) works in Chinese patients. It aims to see if your genetic makeup can predict how you will respond to treatment.
Xuzhou, ChinaAges 25–70 - NCT06324604RecruitingPhase 1
Safety study of MTX-101 in healthy adults
This trial tests a new drug called MTX-101 in healthy volunteers to see if it is safe and how the body processes it. It helps determine the right dose before testing in patients with certain conditions.
Heidelberg, VictoriaAges 18–65 - NCT06329544Recruiting
Study of a high-fructose diet and gut health
This trial tests how a high-fructose diet affects your gut bacteria and overall metabolic health. It is for people who already know they don't absorb fructose well (fructose malabsorbers) and want to understand how this sugar impacts their body.
New York, New YorkAges 25–45 - NCT06330480Enrolling by invitation
Screening for heart rhythm and kidney disease at home
This study is testing whether screening people at home can catch early signs of an irregular heartbeat (atrial fibrillation) and kidney disease. If you're in the right age group and live in one of the selected regions, you could join and help researchers learn more about spotting these conditions early.
AmsterdamAges 50–75 - NCT06335771Recruiting
Study on fat metabolism in obesity and diabetes
This study looks at how fat is processed in the body for people with different health conditions, including obesity and type 2 diabetes. It aims to find new ways to improve treatment by understanding these differences.
Columbia, MissouriAges 18–70 - NCT06336122Recruiting
Peer support for type 2 diabetes in rural Kentucky
This study tests whether talking with a trained peer (someone like you who also has diabetes) can help you manage your blood sugar better. It is for adults 55 and older living in rural Kentucky who have type 2 diabetes with an A1c of 7.5% or higher.
Bowling Green, KentuckyAges 55 years+ - NCT06325202Recruiting
A study on preventing low blood sugar with a closed loop system
This trial tests whether a closed-loop insulin pump combined with education can help people with type 1 diabetes better recognize and avoid dangerously low blood sugar. It may be a good fit if you've had diabetes for a long time and have trouble sensing when your blood sugar drops.
La Jolla, CaliforniaAges 18–75 - NCT06322212RecruitingEarly Phase 1
Type 2 diabetes and brain blood barrier study
This study tests if a treatment can improve the blood-brain barrier in adults with type 2 diabetes. It uses MRI scans to see changes and may help protect brain function.
Los Angeles, CaliforniaAges 40–65 - NCT06278207Recruiting
Finerenone in real-world diabetes and kidney disease
This study looks at how the medication finerenone works in everyday medical practice for people with type 2 diabetes and certain stages of chronic kidney disease. It aims to see how safe and effective the treatment is outside of a clinical trial setting.
Multiple Locations, New JerseyAges 18 years+ - NCT03228732RecruitingEarly Phase 1
Fluoxetine and/or DHEA in people with type 1 diabetes
This early-stage study tests whether the medicines fluoxetine and/or DHEA can improve health in adults with type 1 diabetes. It’s mainly looking for people without major diabetes complications or major medical problems to safely study the effects.
Baltimore, MarylandAges 18–50 - NCT06055036Recruiting
Stress reduction for heart health in Black men
This study looks at how reducing stress can improve cardiovascular health in Black men. It involves lifestyle changes and support to help lower your risk of heart disease.
Columbus, OhioAges 18 years+ - NCT06145308RecruitingPhase 2
Precision treatment for salivary gland cancer
This trial tests a personalized treatment approach for recurrent or metastatic salivary gland cancer. It uses special tests on your tumor to find the best targeted therapy for your specific cancer type.
Beijing, Beijing MunicipalityAges 18–100 - NCT06143566RecruitingPhase 1/Phase 2
Polypill to prevent heart failure in diabetes and kidney disease
This trial tests a 'polypill' (a combination of several medicines in one pill) to prevent heart failure in people with type 2 diabetes and kidney disease. It may help reduce your risk of developing heart muscle problems.
Dallas, TexasAges 18–100 - NCT06112418Recruiting
Personalized vs standard care to prevent heart attacks
This trial compares two ways to prevent heart attacks and strokes: one uses a special heart CT scan to guide care, the other uses standard risk factors like blood pressure and cholesterol. You may be eligible if you are older (men over 55, women over 65) and have diabetes, prediabetes, or metabolic syndrome.
Chandler, ArizonaAges 55 years+ - NCT06120881RecruitingEarly Phase 1
Finding the Right Metformin Dose for Teens with Type 2 Diabetes
This study looks at how to give the right dose of metformin to young people with type 2 diabetes. If you join, you will wear a continuous glucose monitor for 6 weeks to help researchers find the best dose for you.
Oakland, CaliforniaAges 10–21 - NCT05000996Recruiting
Gut microbiome study for people having metabolic surgery
This study looks at your gut bacteria (your “microbiome”) around the time of metabolic surgery. It may help researchers understand how surgery affects gut health and related conditions like diabetes, blood pressure, and cholesterol.
Nashville, TennesseeAges 21–65 - NCT06078683Recruiting
Ketone drink for exercise and heart health in type 2 diabetes
This study tests whether a special ketone drink can improve exercise ability and heart function in people with type 2 diabetes. Participants will have two treadmill exercise tests and heart MRI scans to see how the drink affects their performance and cardiac efficiency.
Columbus, OhioAges 18–80 - NCT06003153RecruitingPhase 4
Gene and sugar response study with oral semaglutide
This study looks at how your genes affect your body's response to a diabetes medication called semaglutide. It may help people with slightly high blood sugar (pre-diabetes) understand why some respond better than others.
Boston, MassachusettsAges 18–65 - NCT06003634Recruiting
Peer Support for Type 2 Diabetes in Rural Kentucky
This study tests whether having a trained peer coach (a person who also has diabetes) can help older adults in rural Kentucky better manage their Type 2 Diabetes. If you join, you'll get support from someone who understands your experience.
Bowling Green, KentuckyAges 55 years+
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Common questions
- Are there clinical trials for diabetes (insulin-requiring, type 1 or type 2)?
- Yes. Clin2 currently lists 2,155 recruiting diabetes (insulin-requiring, type 1 or type 2) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a diabetes (insulin-requiring, type 1 or type 2) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a diabetes (insulin-requiring, type 1 or type 2) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.