Clinical trials
Non-Proliferative Diabetic Retinopathy clinical trials
Below are recruiting non-proliferative diabetic retinopathy clinical trials, each written for real people, not researchers. We’re tracking 14 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06817265RecruitingPhase 3
TNTL for diabetic eye disease (non-proliferative)
This study tests if a drug called TNTL can help people with type 2 diabetes who have early-stage diabetic eye disease (non-proliferative diabetic retinopathy) without severe vision loss. It aims to see if the treatment is safe and effective in slowing or improving the condition.
Xuancheng, AnhuiAges 18–75 - NCT07235085RecruitingPhase 3
Study of OTX-TKI implant for moderate to severe NPDR
This study tests an eye implant (OTX-TKI) that slowly releases a medicine to slow or stop worsening of non-proliferative diabetic retinopathy (NPDR) — an early form of diabetic eye disease. It's for people with moderately severe to severe NPDR who haven't had significant treatments like laser or injections in that eye.
Hagerstown, MarylandAges 18 years+ - NCT07354477RecruitingPhase 2
New eye drop for glaucoma and diabetic retinopathy
This trial tests a new eye drop (QLS-111) to see if it improves blood flow in the back of the eye. It may help people with mild to moderate glaucoma or stable diabetic retinopathy by reducing pressure inside the eye and nourishing the optic nerve.
Palo Alto, CaliforniaAges 18 years+ - NCT06713720Recruiting
Arm Cuff Therapy for Early Diabetic Eye Disease
This study tests if a simple, non-invasive treatment called remote ischemic conditioning (briefly restricting blood flow to one arm using a special cuff) can help slow down early-stage diabetic eye disease in people with type 2 diabetes. You join the study to potentially prevent your retinopathy from getting worse.
Beijing, Beijing MunicipalityAges 40–80 - NCT06701721RecruitingPhase 1
Study of THN391 eye injection for diabetic macular edema
This trial tests an experimental eye injection called THN391 for people with diabetic macular edema, a condition that causes vision loss due to swelling in the back of the eye. The study aims to see if the treatment is safe and may help improve vision.
Parramatta, New South WalesAges 18–80 - NCT07259928RecruitingPhase 2
Testing ANXV for diabetic retinopathy or retinal vein occlusion
This trial tests a new drug called ANXV (Annexin A5) to see if it is safe and can help people with diabetic retinopathy or a recent retinal vein occlusion. The goal is to reduce eye damage and improve vision.
LondonAges 18 years+ - NCT07351786Recruiting
Newer diabetes drugs and eye protection study
This trial is looking at whether newer diabetes drugs (like SGLT2 inhibitors and DPP-4 inhibitors) can help protect the eyes of people with long-standing type 2 diabetes. The study focuses on preventing or slowing diabetic retinopathy, a common eye complication.
AlexandriaAges 25 years+ - NCT03161652RecruitingPhase 2
Levosulpiride for diabetic eye swelling and retinopathy
This Phase 2 study tests whether levosulpiride can improve changes in the retina in people with diabetic retinopathy and diabetic macular edema (eye swelling that can affect vision). It may help by targeting chemicals in the body that could affect eye tissue and inflammation.
Querétaro City, QuerétaroAges 40–69 - NCT07458516Recruiting
Observing eye disease progression in type 2 diabetes
This study closely follows people with type 2 diabetes who have early signs of diabetic retinopathy (damage to the retina from diabetes) to see how the condition changes over time. It does not test a new treatment but monitors the eye's health closely. It may be a good fit if you have diabetic retinopathy that does not need immediate treatment.
CoimbraAges 35–80 - NCT07588100RecruitingPhase 1
Safety study of RO7663498 eye injection for diabetic retinopathy
This is an early-stage safety study testing a new medicine injected directly into the eye to treat diabetic retinopathy (damage to blood vessels in the retina caused by diabetes). The study checks if the medicine is safe and how the body processes it.
Glendale, CaliforniaAges 18 years+ - NCT06951087Enrolling by invitationPhase 3
Steroid injection for diabetic retinopathy with cataract surgery
This trial tests if an injection of dexamethasone (a steroid) into the eye, before or during cataract surgery, can help treat mild to moderate diabetic retinopathy in people with type 2 diabetes.
Nantong, JiangsuAges Any age - NCT07500324Recruiting
Searching for new markers in age-related eye diseases
This study looks for proteins in the blood and eye fluids that may help doctors better understand and monitor three common eye conditions: age-related macular degeneration, diabetic retinopathy, and retinal detachment. If you have one of these conditions, or if you are a healthy control with no retinal disease, you may be able to help by giving a small sample of blood or fluid from your eye during a routine procedure.
Roma, ItalyAges 18 years+ - NCT07038967Recruiting
Cataract surgery and diabetic macular edema progression
This trial studies how diabetic macular edema (swelling in the center of the retina) might change after cataract surgery. It may help doctors understand if surgery is safe for people with this condition.
CairoAges 18 years+ - NCT07170683Enrolling by invitation
Vision test study for macular eye disorders
This study uses a special vision test called microperimetry to track how well the macula (the center of the retina) works in people with certain eye conditions like geographic atrophy or diabetic eye disease. Healthy volunteers are also needed for comparison. The goal is to understand how these conditions affect retinal function over time.
Nottingham, NottsAges 21 years+
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Common questions
- Are there clinical trials for non-proliferative diabetic retinopathy?
- Yes. Clin2 currently lists 14 recruiting non-proliferative diabetic retinopathy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a non-proliferative diabetic retinopathy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a non-proliferative diabetic retinopathy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.