Clinical trials
Disease clinical trials
Below are recruiting disease clinical trials, each written for real people, not researchers. We’re tracking 9,549 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07181109RecruitingPhase 3
Study of zilebesiran for high-risk hypertension patients
This trial tests a new medicine called zilebesiran for people with high blood pressure that isn't well controlled. It may be an option if you have heart or blood vessel disease, or are at high risk for it.
Birmingham, AlabamaAges 18 years+ - NCT07678619Enrolling by invitation
Smart tools for infectious disease decisions
This study tests a smart analysis system to help local health officials make better decisions during infectious disease outbreaks. It aims to see if this tool improves speed and accuracy in responding to diseases like COVID-19, mpox, or flu.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06430684RecruitingEarly Phase 1
SGLT2 inhibitor trial for children with kidney disease
This trial tests a medication called SGLT2 inhibitor (a type of diabetes drug that may also help protect the kidneys) in children with chronic kidney disease. It aims to see if the drug is safe and easy to use in children ages 2–18 with moderate to severe kidney problems.
Chicago, IllinoisAges 12–25 - NCT07769437Recruiting
Sweetener study for crohn's disease in remission
This study looks at how non-nutritive sweeteners (like those in diet drinks) affect people with Crohn's disease who are currently in remission. By tracking what you eat and your symptoms, researchers hope to learn if these sweeteners influence disease activity.
Chagrin Falls, OhioAges 18–70 - NCT07214376Recruiting
Nerve ablation for pulmonary hypertension from left heart disease
This trial tests a device that uses a catheter to deliver energy to nerves around the pulmonary arteries, aiming to reduce high blood pressure in the lungs caused by left heart failure. It is for people with ongoing heart failure symptoms despite optimal medications.
Tucson, ArizonaAges 18–85 - NCT07031531Recruiting
AI heart health program for young adults
This study tests if an AI-powered system can help manage premature coronary artery disease in adults aged 18 to 45. It uses a smartphone app to support treatment and improve outcomes.
Hefei, AnhuiAges 18–45 - NCT07768579Recruiting
Sequential treatment for Alzheimer's disease
This study tests a sequence of treatments to see if they can help people with Alzheimer's disease or mild cognitive impairment. It aims to slow down memory decline and improve daily function.
Beijing, Beijing MunicipalityAges 55–85 - NCT06560021Enrolling by invitation
Random biopsies in inflammatory bowel disease surveillance
This trial looks at whether taking random biopsies during a routine colonoscopy is helpful for people with inflammatory bowel disease (IBD) who are at risk for colon cancer. It aims to understand if random biopsies can detect early signs of cancer or pre-cancer.
Birmingham, AlabamaAges 18 years+ - NCT06451588RecruitingPhase 2
Fecal transplant for inflammatory back pain
This study tests whether a fecal microbiota transplant (a procedure that transfers healthy bacteria into your gut) can reduce inflammation and improve symptoms in people with inflammatory back pain (axial spondyloarthritis). It may help if your current treatments are not working well enough.
TromsøAges 18–65 - NCT07113743Enrolling by invitationPhase 1/Phase 2
Gene therapy for x-linked chronic granulomatous disease
This trial tests a new gene therapy for X-linked chronic granulomatous disease (CGD), a condition where the immune system cannot fight certain infections. The treatment uses your own blood stem cells, which are modified in the lab to help your body produce working immune cells.
Bethesda, MarylandAges 3–60 - NCT05183165Recruiting
Study measures copper levels in breast milk for Wilson’s disease
This study measures how much copper is present in breast milk in people with Wilson’s disease. It aims to provide safer guidance for breastfeeding during treatment, including during pregnancy.
ParisAges 18 years+ - NCT07761936RecruitingPhase 3
Safinamide for Parkinson's disease pain
This study tests whether safinamide, an add-on medication for Parkinson's disease, can reduce chronic pain in people who also experience motor fluctuations (times when symptoms return between doses). It aims to see if this treatment can improve pain and quality of life.
Verona, VenetoAges 18 years+ - NCT05124392Recruiting
Observational study of biomarkers in people at risk for prion disease
This study looks for early signs of prion disease in people who are at risk, using blood tests, spinal fluid, and thinking tests. It hopes to find ways to diagnose and track the disease earlier.
Charlestown, MassachusettsAges 18–85 - NCT07348640RecruitingPhase 3
Study of new MRI dye for blocked blood vessels
This trial tests a new MRI contrast dye (gadopiclenol) to see if it works as well as the standard dye for finding blocked or narrowed blood vessels. If you have symptoms of vascular disease, you may be able to join and help compare the two dyes.
Los Angeles, CaliforniaAges 18 years+ - NCT07727083Recruiting
Study of EBV-positive T/NK-cell lymphoma and related diseases
This study collects medical information and blood samples from people with Epstein-Barr virus-positive T/NK-cell lymphoproliferative diseases to better understand how these conditions progress and respond to treatment. It includes a retrospective part (looking back at medical records) and a prospective part (following people forward in time).
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07143669Recruiting
Screening study for mast cell disease with KIT mutation
This study looks for a specific gene change (KIT D816V) in people with certain allergic reactions or related conditions. It aims to find those who might benefit from future treatments targeting this mutation.
Birmingham, AlabamaAges 18 years+ - NCT00344188Recruiting
Study of Leishmania infections
This trial studies people with Leishmania infections (a parasitic disease often from sand fly bites). Researchers aim to better understand and treat the infection, and you may benefit from expert care.
Bethesda, MarylandAges 3–100 - NCT07570316RecruitingPhase 3
Testing efgartigimod for Graves' disease hyperthyroidism
This study tests whether efgartigimod, an injectable medication given under the skin, can help control overactive thyroid (Graves' disease) in adults already taking methimazole or carbimazole. The goal is to see if it reduces thyroid antibodies and improves thyroid hormone levels.
Orange, CaliforniaAges 18 years+ - NCT07535008Recruiting
Dental Cleaning to Prevent Graft-Versus-Host Disease
This study tests whether professional dental cleaning after a stem cell transplant can help prevent chronic graft-versus-host disease (GVHD), a condition where transplanted immune cells attack your body. You'll receive dental cleanings and be followed for one year to see if this simple preventive step reduces GVHD complications.
Seattle, WashingtonAges 18 years+ - NCT07754097Recruiting
Tracking your health at home for chronic kidney disease
This study tests if regularly tracking your blood pressure, diet, and medications through a mobile app can help monitor kidney disease progression. It aims to see if this self-management approach helps you stay healthier.
Daejeon, DJAges 19–84 - NCT03884075RecruitingPhase 2
Semaglutide study for fatty liver and how sugar affects the liver
This Phase 2 study tests how semaglutide (a diabetes medication also used for weight) affects fatty liver and the liver’s response to sugar. It may help people with non-alcoholic fatty liver disease understand whether the drug improves liver fat and related changes.
Bethesda, MarylandAges 18–100 - NCT04703179Enrolling by invitation
Rare disease and undiagnosed case research blood and tissue biobank
This study collects and stores samples and related medical information for people with rare diseases or suspected genetic conditions. It may help researchers better understand these conditions and develop future testing and treatments.
Scottsdale, ArizonaAges Any age - NCT05656378Recruiting
Storing samples to study how the body interacts with microbes
This study creates a storage bank of biological samples like blood, stool, and tissue. Researchers will use these samples to learn how the body interacts with the natural microbes that live in and on us, which may help improve treatments for many diseases.
Bethesda, MarylandAges Any age - NCT07752355Recruiting
Parkinson's subtypes and causes in young onset disease
This study looks at different types of Parkinson's disease, especially in people diagnosed before age 50. It involves a small skin biopsy to help understand what causes the disease.
New York, New YorkAges 18 years+
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Common questions
- Are there clinical trials for disease?
- Yes. Clin2 currently lists 9,549 recruiting disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.