Clinical trials
Disease clinical trials
Below are recruiting disease clinical trials, each written for real people, not researchers. We’re tracking 9,374 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05822609RecruitingPhase 2
Semaglutide for kidney disease in adults with type 1 diabetes
This Phase 2 study tests semaglutide (a diabetes and weight-related medicine) to see if it can slow or improve diabetic kidney disease in people with type 1 diabetes. You may be able to join if you have type 1 diabetes for at least 5 years and ongoing signs of kidney damage measured in urine tests.
Aurora, ColoradoAges 18 years+ - NCT05841199Recruiting
Study heart blood flow during fast heart rates
This study measures how well blood flows through the heart when the heart rate is increased during a heart procedure. It may help doctors better understand coronary (heart artery) blood flow and how to guide treatment when you need angiography or angioplasty.
LondonAges 18 years+ - NCT05835271Enrolling by invitation
Hip exoskeleton to help walking in severe lung disease
This trial tests a powered hip exoskeleton device to improve walking ability in people with stable, severe lung-related breathing problems. It may help you walk farther or more comfortably by supporting your movement, as long as your heart, blood pressure, and skin/body fit are safe for the device.
Toronto, OntarioAges 18 years+ - NCT05812755RecruitingPhase 4
Study drug effects on blood vessels and organs in heart surgery
This Phase 4 trial studies vericiguat-like stimulation (a type of medicine that affects blood-vessel signaling) around the time of planned open-heart surgery. It aims to see whether this can change blood-vessel “reactivity” and reduce injury to organs during and after surgery.
Nashville, TennesseeAges 18 years+ - NCT05767047RecruitingPhase 3
Apremilast study for children with mouth ulcers from Behçet’s
This trial studies whether apremilast can help reduce mouth ulcers in children who have Behçet’s disease or juvenile psoriatic arthritis. You may be considered if your child finished a main study and is under 18, and can safely continue treatment.
ThessalonikiAges 5–18 - NCT05795634Recruiting
Study stress effects in people at risk for Alzheimer’s
This study looks at how stress may affect thinking and memory in people with mild cognitive impairment (MCI) who are at risk for Alzheimer’s disease. You may be asked to do thinking tests and also involve a knowledgeable person who can report on changes over time.
Baltimore, MarylandAges 60 years+ - NCT05805839Enrolling by invitationPhase 2
Study uses brain scans to understand demyelinating diseases
This trial compares scan results in people with multiple sclerosis or related demyelinating conditions versus people without inflammatory demyelinating diseases. The goal is to better understand what’s happening in the brain and how sex differences may play a role.
Rochester, MinnesotaAges 18 years+ - NCT05788666Recruiting
GeriKit check-up for older adults after heart artery problems
This trial tests a “GeriKit” set of questions and measurements to better understand health and needs in people age 75+ after a heart attack or related procedures. It may help doctors plan more personalized care during recovery.
New York, New YorkAges 75–100 - NCT05785065RecruitingPhase 2
Mycophenolate for early lung scarring in systemic sclerosis
This Phase 2 study tests whether mycophenolate mofetil (MMF) can slow or improve early, mild lung scarring in people with systemic sclerosis. It’s meant for systemic sclerosis patients who have lung involvement on a CT scan but still have good breathing test results.
Montreal, QuebecAges 18 years+ - NCT05783375Recruiting
Rheumatic heart prevention program for Ugandan communities
This study helps deliver prevention care for rheumatic heart disease in specific districts of northern Uganda. If you live there (or provide care in the selected clinics), the program may offer extra support to help stop heart damage before it starts.
Kampala, UgandaAges 5 years+ - NCT05785156Recruiting
Quick test study to predict stroke and memory disease outlook
This study tests quick new methods to measure “slowed actions” in people with stroke or memory-related brain conditions. The goal is to see whether these quick tests can help predict future outcomes and guide care.
AmiensAges 40–85 - NCT05810181Recruiting
Interviews to improve choices about gene therapy for rare diseases
This study uses one-on-one interviews to learn what families and clinicians need to make decisions about gene therapy for rare diseases. The goal is to create or improve decision tools that make gene therapy information easier to understand and act on.
Memphis, TennesseeAges 8 years+ - NCT05779475Enrolling by invitation
Study of people with moderate Parkinson’s disease
This is an observational study, meaning it doesn’t test a new drug—researchers mainly follow people to better understand moderate Parkinson’s disease and who may be good candidates for future cell therapy. If you have moderate symptoms that aren’t well controlled with tablets, this study may help inform better future treatments.
Irvine, CaliforniaAges 50–68 - NCT05764642Enrolling by invitationPhase 2
Ultrasound imaging of kidney blood vessels in kidney disease
This Phase 2 study tests an ultrasound imaging method to look at tiny blood vessels in the kidneys. It may help doctors better understand chronic kidney disease, especially when a kidney biopsy is already planned for medical reasons.
Jacksonville, FloridaAges 18 years+ - NCT05748028Recruiting
Testing treatment for pain and nerve symptoms in Parkinson’s
This study looks at pain and “autonomic” (automatic body) symptoms in people with Parkinson’s disease or a related condition called multiple system atrophy. It aims to understand what helps and to learn more about these symptoms in different types of Parkinson-like illnesses.
Telese Terme, BeneventoAges 18 years+ - NCT05776251Recruiting
Noninvasive nerve stimulation for ongoing Lyme symptoms
This trial tests whether taVNS (a noninvasive nerve stimulation done through the skin near the ear) can reduce long-lasting symptoms after Lyme disease. It targets people whose symptoms have stayed for months after standard antibiotic treatment.
New York, New YorkAges 18–65 - NCT05759468RecruitingPhase 2
Add NAD to help protect kidneys in diabetes
This Phase 2 study tests whether adding NAD can improve kidney health in people with diabetes-related kidney disease. It is designed for people with certain urine lab results showing kidney stress, while keeping blood sugar and safety limits within range.
Boston, MassachusettsAges 30 years+ - NCT05765110Recruiting
Tracking speech, movement, and thinking in Parkinson’s disease
This study looks at how people with Parkinson’s disease speak, move, and think to see whether these patterns can act like a “biomarker” (a measurable sign) of the disease. It also involves healthy volunteers to compare results.
PragueAges 30–75 - NCT05759780Recruiting
Check how an eye probe measures tissue softness
This study uses a special eye/skin/gum imaging test to measure how tissues behave. It may help researchers improve noninvasive ways to understand eye and tissue health, and in some parts of the study, mild keratoconus.
Boston, MassachusettsAges 18–75 - NCT05758467Enrolling by invitation
Study linking adult oral health, social factors, and heart health
This study looks at how people’s oral health in adulthood relates to social factors and heart health. To join, you must have already taken part in specific past health surveys.
BergenAges 71–72 - NCT05776641Recruiting
Light and sound training to help prevent Alzheimer’s memory loss
This study tests whether regular “gamma” light and sound stimulation can delay or prevent Alzheimer’s disease-related memory decline in people who are currently not showing dementia but are at higher risk. It uses brain testing (MRI and PET) and memory/language tests over about 13 months.
Boston, MassachusettsAges 55–90 - NCT05366153Recruiting
Plan to lower future heart attack risk after past cancer treatment
This trial tests whether a “risk-guided” care plan can help prevent coronary artery disease (the buildup that can lead to heart attacks) in people who had cancer treatment that can affect the heart. You may get closer heart risk monitoring and guidance to reduce risk factors, such as cholesterol—especially if you can safely take statins.
Hobart, TasmaniaAges 40–70 - NCT05738824Recruiting
Study how inflammatory muscle diseases naturally change over time
This study follows people with suspected or confirmed inflammatory muscle disease (and sometimes healthy adults) to better understand how the condition progresses and what changes over time. It may help researchers identify patterns that could guide future treatments.
Bethesda, MarylandAges 2–120 - NCT05744713Enrolling by invitation
Study of adults with long-term liver disease using health records
This observational study looks at adults with chronic liver disease (including cirrhosis) to better understand how people are managed and how they feel over time. Because it does not change your treatment, it may help researchers improve care and patient support.
Los Angeles, CaliforniaAges 18 years+
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Common questions
- Are there clinical trials for disease?
- Yes. Clin2 currently lists 9,374 recruiting disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.