Clinical trials
Disease clinical trials
Below are recruiting disease clinical trials, each written for real people, not researchers. We’re tracking 9,583 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05501587Recruiting
Respiratory Health Registry measuring lung function in different groups
This registry study collects information and measures lung function to better understand respiratory health across people with cystic fibrosis, other lung diseases, and healthy volunteers. Your results may help researchers track lung health and improve future research and care.
Vancouver, British ColumbiaAges birth–99 years - NCT05502198Recruiting
How muscle loss matters in advanced liver disease
This study looks at how loss of muscle strength or mass (sarcopenia) relates to advanced liver disease. It may help doctors understand which patients are at higher risk and could guide future care choices.
EksjöAges 18 years+ - NCT05506293Recruiting
Registry study for sealing leaking heart valve devices
This is a study that collects information from people who are having a minimally invasive procedure to close a leak around a heart valve replacement device. It may help doctors better understand how well this procedure works and what outcomes to expect.
CharleroiAges 16–110 - NCT05507242RecruitingPhase 2
Drug that blocks TSLP to reduce COPD flare airway inflammation
This Phase 2 trial tests whether blocking TSLP can reduce inflammation in the airways of people with COPD, especially around flare-ups. If you often need prednisone and/or antibiotics for COPD exacerbations, this study may help determine a new treatment approach.
CopenhagenAges 40 years+ - NCT05508165Recruiting
Compare virtual vs in-person care for urinary symptoms
This study compares how patients do when their urinary problem is worked up and treated virtually versus in person. It mainly aims to see if virtual visits are satisfying and effective for men with urinary retention, enlarged prostate (BPH), or other urinary tract symptoms.
Indianapolis, IndianaAges 18 years+ - NCT05509010Recruiting
AI registry using CT scan to assess coronary artery disease
This trial builds and tests an AI system using information from a heart CT scan to help evaluate coronary artery disease (clogged heart arteries). If you need a CT coronary angiography for medical reasons, this may help improve how such scans are analyzed and used in care.
SingaporeAges 21–80 - NCT05509153RecruitingPhase 2
N-acetylcysteine trial for people at risk of Huntington’s disease
This Phase 2 study tests whether NAC (a supplement-like medicine) can delay symptoms in people who carry the Huntington’s disease gene expansion but do not yet have clear movement symptoms. You may be asked to take NAC and attend regular visits, scans, and blood tests to see if it changes how likely you are to develop Huntington’s disease within the next 10 years.
Westmead, New South WalesAges 18 years+ - NCT05514769Recruiting
Surgery type comparison for early-to-mid stomach cancer
This trial compares two different stomach cancer surgeries after removing the tumor, to see which works better for patients with stomach adenocarcinoma. It may help determine the safest approach and best recovery outcomes for people whose cancer has not spread.
Nanchong, SichuanAges 18–85 - NCT05514899RecruitingPhase 2
Cannabidiol and THC study for gut health and brain inflammation in HIV
This Phase 2 study tests whether cannabidiol (CBD) and tetrahydrocannabinol (THC) change the gut microbiome and brain-related inflammation in people with HIV. It may help researchers understand new ways to reduce inflammation, but you would need strict cannabis and CBD/THC avoidance during the study.
San Diego, CaliforniaAges 21–70 - NCT05515770RecruitingPhase 3
Injectable PrEP shot for HIV prevention in higher-risk adults
This Phase 3 study tests whether an injectable HIV prevention medicine (cabotegravir) given before exposure can help prevent HIV in people at higher risk. You may join if you are HIV-negative and meet specific sexual health, medication, and health-testing requirements.
Rio de JaneiroAges 18–30 - NCT05516069Recruiting
Using a self-serve kiosk to test for HIV and reduce harm
This study tests an interactive, self-serve machine (kiosk) to help people access HIV testing and other harm-reduction services more easily. It may help by making testing and support more private and simpler to use.
Moncton, New BrunswickAges 16 years+ - NCT05519111RecruitingPhase 2
Cannabinoid treatment to lower inflammation and sickle pain
This Phase 2 study tests a cannabinoid medicine (dronabinol) to reduce inflammation and pain related to sickle cell disease. It may help you have less pain that interferes with daily life if you meet the study requirements and can safely avoid cannabis during the study.
New York, New YorkAges 18 years+ - NCT05519475RecruitingPhase 2
Gene-silencing medicine trial for adults with MASH and liver scarring
This Phase 2 study tests a gene-silencing treatment to improve chronic liver disease called MASH, especially in people with certain genetic risk. You may be eligible if you have MASH with moderate-to-advanced scarring and specific test results, and if other liver causes and recent substance/alcohol issues don’t apply.
Chandler, ArizonaAges 18–75 - NCT05521503Recruiting
Collecting heart tissue samples for a shared research database
This trial builds a database by collecting and storing biopsy or biopsy-related samples from adults being evaluated for certain heart conditions. It may help researchers study heart disease and amyloidosis by making past tissue samples easier to access for future research.
Lexington, KentuckyAges 18 years+ - NCT05521789RecruitingPhase 4
Erector spinae block for thoracic surgery pain relief
This trial tests a specific pain-block injection (called an erector spinae block) to help with pain during thoracic surgery that removes part of the lung. You might benefit from better pain control and possibly fewer pain medicines, depending on what the study finds.
Washington D.C., District of ColumbiaAges 18–90 - NCT05522218Recruiting
Eluvia stent for blocked or narrowed leg artery
This trial looks at using an Eluvia drug-coated stent to treat a blocked or severely narrowed artery in the upper leg/knee area. It may help improve blood flow to the leg, and the study will follow patients to see how they do over time.
Hangzhou, ZhejiangAges Any age - NCT05525039Recruiting
Vibration plus supplement trial for weak muscles and nerves
This trial studies whether a vibration treatment combined with an HMB supplement can improve weak muscle quality and reduce early nerve-to-muscle connection problems. It is mainly for older adults who already have signs of low muscle strength or function.
Hong KongAges 60 years+ - NCT05525312Recruiting
Two breathing strategies during lung surgery for lung cancer
This trial compares two ways of managing breathing while you have surgery to remove lung cancer. It may help doctors figure out which strategy is safer and works better during the operation.
MontpellierAges 18 years+ - NCT05526963Recruiting
Help reduce unnecessary medicines in older adults
This study aims to reduce the number of long-term medicines older adults take when they have multiple chronic conditions. It may help by simplifying medicine routines and improving safety and care coordination with a family doctor.
Halle, Saxony-AnhaltAges 70 years+ - NCT05528744Recruiting
Study genes and symptoms in ANKRD17-related CAGS
This study looks at how a specific gene change in ANKRD17 relates to the symptoms, brain/scan findings, and brain-cells in people with Chopra-Amiel-Gordon syndrome (CAGS). It may help families understand the condition better and connect gene results to what is seen clinically.
Boston, MassachusettsAges Any age - NCT05529459Recruiting
Guidance method for opening heart blockages with stents
This study compares two ways of deciding how completely to open blocked heart arteries using drug-eluting stents. It aims to see which guidance approach improves results and safety for people with coronary artery disease who need a PCI (heart catheter procedure).
AnyangAges 19 years+ - NCT05530408Recruiting
Pulmonary scan imaging registry and blood sample collection
This trial builds a research database from people who take lung scans like pulmonary MRI or CT at the University of Kansas Medical Center. It may help researchers better understand lung disease and improve future diagnosis or treatment.
Kansas City, KansasAges 18 years+ - NCT05532631Recruiting
Compare stent procedure versus bypass surgery for weak heart
This study compares two ways to improve blood flow to the heart—using stents through a catheter or bypass surgery—in people with heart muscle weakness and blockages in more than one coronary artery. It may help identify which approach leads to better outcomes over at least two years.
Créteil, Val De MarneAges 18 years+ - NCT05543681RecruitingPhase 2
Study drug for agitation in Alzheimer’s dementia with caregiver support
This Phase 2 trial tests a study medicine to reduce “agitation” behaviors in people with Alzheimer’s dementia. You and your caregiver would complete required assessments and may need genetic and blood testing to check how the body handles the drug.
Maitland, FloridaAges 60 years+
Hear when a new Disease trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for disease?
- Yes. Clin2 currently lists 9,583 recruiting disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.