Clinical trials
Disease clinical trials
Below are recruiting disease clinical trials, each written for real people, not researchers. We’re tracking 9,506 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03142152Recruiting
Mitral valve implant for heart failure with leaky mitral valve
This trial tests whether a device called the Carillon Mitral Contour System can help people with heart failure caused by a mild-to-moderate leaky mitral valve. You’d be compared against a control group, and the goal is to improve heart failure symptoms and outcomes.
Gilbert, ArizonaAges 18 years+ - NCT03065413Recruiting
Study of heart health, habits, and mood in sailors
This study looks at how common heart and blood vessel problems are, and how changes in activity, diet, and anxiety or depression show up over time in naval personnel. It may help improve understanding of risk factors and mental well-being in this group.
Athens, AthensAges 18 years+ - NCT03240653Recruiting
Study to sort people with Gaucher disease into groups
This study looks at people with Gaucher disease (types I, II, or III) to better “group” patients for understanding and future research. If you (or your child) have confirmed Gaucher disease, you may be asked to share information and follow a study schedule.
BirminghamAges Any age - NCT05432349Recruiting
Rett syndrome genetic registry for MECP2 changes
This trial is a registry that collects health and genetic information from people with Rett syndrome. It may help researchers better understand how MECP2 loss-of-function changes lead to symptoms and how to support patients.
Birmingham, AlabamaAges birth–99 years - NCT07115953Recruiting
Spiral nerve treatment for uncontrolled high blood pressure
This trial tests a new procedure to treat high blood pressure by using a special catheter to calm overactive nerves in your kidneys. It may help you achieve better blood pressure control if medications are not enough.
MelbourneAges 18 years+ - NCT03011541Recruiting
Stem cell treatment for damaged retina or optic nerve
This study looks at stem-cell treatment to help vision in adults whose retina or optic nerve damage is not expected to improve on its own. You may be a candidate if your eye exam shows documented, stable or slowly changing damage and you can safely complete follow-up eye visits.
Westport, ConnecticutAges 18 years+ - NCT02402660Enrolling by invitationPhase 2
Test ALK-001 for Stargardt disease eye changes and comfort
This Phase 2 study tests how well ALK-001 is tolerated and whether it can slow or improve vision-related changes in people with Stargardt disease. It mainly looks at safety (tolerability) and signs in the eye over about 24 months.
Phoenix, ArizonaAges 8–70 - NCT02791854Enrolling by invitation
Improving Care for Adults With Crohn’s or Ulcerative Colitis
This trial looks at ways to improve care for adults living with inflammatory bowel disease, including Crohn’s disease and ulcerative colitis. You may be invited if your clinic is part of an inflammatory bowel disease care network called IBD Qorus.
Los Angeles, CaliforniaAges 18–99 - NCT01440218Enrolling by invitation
Study for rare illnesses and treatment reactions in families
This trial looks for answers in rare illnesses that either have no known cause or have not improved with usual treatments. It also studies rare harmful reactions that happen after medicines, vaccines, or medical devices, and may involve family members of the affected person.
La Jolla, CaliforniaAges Any age - NCT01852370Enrolling by invitationPhase 1/Phase 2
Lung and bone marrow transplant plan for immune system disorders
This early-phase study tests a step-by-step transplant approach: first replacing the lungs, then doing a bone marrow (stem cell) transplant to treat certain immune deficiency diseases. It may help people whose immune problem has led to severe, end-stage lung disease.
Pittsburgh, PennsylvaniaAges 5–45 - NCT07411729Recruiting
Building a sample bank for faster diagnosis
This study creates a bank of leftover blood and other samples from patients at two French hospitals. It helps researchers test new, faster ways to diagnose diseases.
Le Kremlin-BicêtreAges 18 years+ - NCT07421258Recruiting
Study of treat-to-target in Crohn's and colitis
This study looks at how well a treat-to-target approach works for people with Crohn's disease or ulcerative colitis in everyday medical care. By reviewing your medical history over the past 2 years, researchers hope to learn how to better manage these conditions and prevent long-term damage.
Chongqing, Chongqing MunicipalityAges 20 years+ - NCT07422675RecruitingPhase 1
Study of a new treatment for Parkinson's with motor fluctuations
This study tests a new single-dose treatment for Parkinson's disease to see if it can help reduce 'off' time—when medication wears off and symptoms return. It is for people who experience motor fluctuations and are already on a stable medication routine.
Englewood, ColoradoAges 40–80 - NCT07444060Recruiting
Guselkumab vs Ustekinumab for stricturing Crohn's disease
This study compares two medicines, Guselkumab and Ustekinumab, for people with Crohn's disease that causes narrowing (strictures) in the bowel. It aims to find which works better to improve symptoms and avoid the need for more procedures.
Hangzhou, ZhejiangAges 18–80 - NCT07446296Recruiting
Kidney transplant exercise program for older adults
This trial tests whether a special exercise program can help people on the kidney transplant waiting list get stronger and improve their health. You would use an app to follow exercise routines at home and check in with the research team.
Philadelphia, PennsylvaniaAges 60 years+ - NCT07449117Recruiting
Brain stimulation for language in mild cognitive decline
This study tests a new type of gentle brain stimulation (called temporal interference) to see if it can improve language processing in people with mild cognitive impairment. The stimulation uses electrodes placed on the head and is done while you are in an MRI scanner.
Brno, South MoravianAges 60–80 - NCT07462260RecruitingPhase 2/Phase 3
Sildenafil for severe pulmonary hypertension from rheumatic valve disease
This trial tests if sildenafil can help people with severe pulmonary hypertension caused by rheumatic valvular heart disease. It aims to see if the drug improves symptoms and heart function.
Hyderābād, SindhAges 18 years+ - NCT07472738Recruiting
Studying treatable traits in chronic airway diseases
This trial is studying people with chronic lung conditions, like COPD or asthma, to find treatable traits. It also includes healthy volunteers for comparison, to better understand what makes these diseases different and how to personalize treatment.
Beijing, Beijing MunicipalityAges 20–75 - NCT07476365Recruiting
Finding new markers for early CMT1A disease
This study looks for new markers of early Charcot-Marie-Tooth 1A (CMT1A) disease using blood tests and special MRI scans. It aims to help understand how the disease progresses and may lead to better treatments.
GöttingenAges 10–30 - NCT07477197Recruiting
Heart Institute Biobank for Adult Congenital Heart Disease
This study collects blood and tissue samples and health information from adults with or at risk for congenital heart disease or related heart conditions. It aims to help researchers better understand these conditions and improve future treatments.
Cincinnati, OhioAges 16 years+ - NCT07006506RecruitingPhase 2
Belumosudil to prevent graft-versus-host disease after transplant
This study tests whether a drug called belumosudil can help prevent graft-versus-host disease (GVHD) after a stem cell transplant. It is for people who have had a recent transplant and are at risk for GVHD.
Basking Ridge, New JerseyAges 18 years+ - NCT07672977Enrolling by invitation
Sound therapy at home to improve deep sleep in early Alzheimer's
This study tests whether a wearable device that plays soft sounds during sleep can boost deep sleep brain waves in people with mild memory problems caused by Alzheimer's. It aims to see if this simple, home-based approach can help protect memory and thinking.
Zaragoza, ZaragozaAges 50–75 - NCT07487480Recruiting
Guselkumab for Crohn's after ustekinumab
This study looks at whether guselkumab, a different biologic medicine, can help people with Crohn's disease who have already tried ustekinumab but it didn't work well or caused side effects. It aims to see if switching to guselkumab is safe and effective.
Hangzhou, ZhejiangAges 18–75 - NCT07488091Recruiting
Sickle cell pregnancy care program in Ghana
This trial tests a team-based care program for pregnant women with sickle cell disease. It aims to improve health for both mothers and babies through regular checkups and support.
AccraAges 18–45
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Common questions
- Are there clinical trials for disease?
- Yes. Clin2 currently lists 9,506 recruiting disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.