Clinical trials
Disease clinical trials
Below are recruiting disease clinical trials, each written for real people, not researchers. We’re tracking 9,353 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05084937Enrolling by invitation
Study on celiac disease from teens into adulthood
This trial looks at how people with celiac disease transition from childhood into adulthood, using questionnaires. It also includes people without celiac disease for comparison, to help researchers understand similarities and differences during these teen years.
KuopioAges 13–19 - NCT05124392Recruiting
Observational study of biomarkers in people at risk for prion disease
This study looks for early signs of prion disease in people who are at risk, using blood tests, spinal fluid, and thinking tests. It hopes to find ways to diagnose and track the disease earlier.
Charlestown, MassachusettsAges 18–85 - NCT05036707RecruitingPhase 1/Phase 2
Tick bite study in healthy adults
This study looks at how your body's immune system reacts to a tick bite. It may help doctors understand and prevent tick-borne diseases, which are illnesses spread by ticks, like Lyme disease.
Bethesda, MarylandAges 18–99 - NCT05007990Recruiting
Interview study of caregiving networks over a person’s life
This study uses interviews and questionnaires to better understand who makes up a caregiver’s support network when caring for someone with a long-term health condition. Your answers may help researchers understand how caregiving changes over time and across different health situations.
Bethesda, MarylandAges 18–100 - NCT05051254Recruiting
Breathing muscle testing in children with breathing muscle weakness
This study looks at how hard it is for children to breathe and how their breathing muscles work, using specific breathing-related tests. It may help doctors better understand breathing problems and choose care more effectively.
ParisAges birth–17 years - NCT05010603Recruiting
Studies families to understand late-onset Alzheimer’s
This study focuses on people with late-onset Alzheimer’s (and some similar memory diseases) and uses a close family “informant” to share what they’ve noticed. It may help researchers learn more about these conditions and how they progress in families.
Washington D.C., District of ColumbiaAges 55 years+ - NCT04864886Recruiting
Study how immune-related conditions affect metabolism
This study collects blood and other samples to see how the immune system changes “metabolism” (how your body uses energy) in people with immune-related conditions. Your samples may also be stored for future research and could help researchers better understand immune health.
Bethesda, MarylandAges 18–75 - NCT04896138Enrolling by invitation
Natural history study for lung scarring patients
This study follows people who are being seen for lung scarring (also called ILD) and compares them with family members without lung scarring. It helps researchers better understand how this condition changes over time and what to look for in the future.
Charlottesville, VirginiaAges 18 years+ - NCT04777656RecruitingPhase 3
Crohn’s exclusion diet plus usual care for kids
This study tests whether a specific “exclusion diet” (removing certain foods) added to standard treatment can better control unstable Crohn’s disease in children. It may help reduce inflammation and flare-ups when symptoms are not controlled by usual medicines.
BronAges 6–17 - NCT04844606RecruitingPhase 3
Mirikizumab for kids with ulcerative colitis or Crohn’s
This study checks whether continuing mirikizumab (a medicine that calms gut inflammation) helps children with ulcerative colitis or Crohn’s disease after prior study treatment. It aims to see if staying on the medicine is beneficial and safe over time.
San Francisco, CaliforniaAges 2–19 - NCT04701177Enrolling by invitation
Smartphone-based study of brain biomarkers in memory clinic patients
This observational study follows people with (or at risk for) Alzheimer’s-related brain changes and a comparison group without them. It uses clinic visits, cognitive testing, questionnaires, and possibly a spinal fluid test to better understand brain biomarkers and how they relate to thinking and daily life.
Corfu, CorfuAges 45 years+ - NCT04690972Recruiting
Collection of blood and tissue samples for liver disease research
This study builds a research library of biological samples (like tissue and blood) from people with chronic liver disease. It aims to create better lab and preclinical models of tumors and long-term liver problems, which may help future treatments.
StrasbourgAges 18 years+ - NCT04703179Enrolling by invitation
Rare disease and undiagnosed case research blood and tissue biobank
This study collects and stores samples and related medical information for people with rare diseases or suspected genetic conditions. It may help researchers better understand these conditions and develop future testing and treatments.
Scottsdale, ArizonaAges Any age - NCT04715399Recruiting
Research study collecting data for neurodegenerative diseases
This study collects health information from people with neurodegenerative diseases, some family members, and healthy controls to help researchers better understand these conditions. It may help future diagnosis and research, and participation may include noninvasive checks and other procedures depending on your situation.
Philadelphia, PennsylvaniaAges 18 years+ - NCT04770571Enrolling by invitation
Study of posterior neck and upper-back spine fixation systems
This trial studies specific surgical hardware used to stabilize the back of the neck and upper back during spine surgery. It may help surgeons compare outcomes for people needing fixation for trauma, instability, failed prior fusion, tumors, or certain degenerative conditions.
Orange, CaliforniaAges 18 years+ - NCT03799991Recruiting
Balance therapy for people with early-to-moderate Alzheimer’s
This trial tests whether an 8-week balance and movement program can help people with early-to-moderate Alzheimer’s who also have inner-ear (vestibular) balance loss. You and a caregiver may learn exercises and attend weekly visits, while researchers compare the results to an active control program.
Baltimore, MarylandAges 60 years+ - NCT04666402Recruiting
Testing better ways to diagnose early liver disease
This study looks at integrated diagnostic tests to find early liver problems sooner. It may help you (if referred to the community liver clinic) get more timely information about what’s going on.
Manchester, Greater ManchesterAges 18 years+ - NCT04671771Recruiting
Testing a new graft for hemodialysis access in kidney failure
This study tests whether an “AV graft” implant works safely and well for people with end-stage kidney disease who need hemodialysis. It may help your dialysis access last and work better, compared with current expectations for AV grafts.
Phoenix, ArizonaAges 18–90 - NCT04624490RecruitingPhase 1
Lung function MRI using a special gas in volunteers
This Phase 1 study tests a lung scan that uses a special gas and MRI to measure how well your lungs work. It includes healthy volunteers and people with lung disease to see how well the scan works and how safe it is.
Kansas City, KansasAges 3 years+ - NCT04663204RecruitingPhase 2
Sparsentan study for IgA kidney disease in adults
This Phase 2 trial studies whether sparsentan is safe and can slow down kidney damage in adults with IgA nephropathy (IgAN). Participants may receive sparsentan to improve kidney-related measures such as protein in the urine.
Cambridge, EnglandAges 18 years+ - NCT04645199Recruiting
Long-term follow-up study for blood and bone marrow diseases
This study is collecting long-term follow-up information from people diagnosed with certain blood and bone marrow conditions. It may help doctors understand what happens over time and improve future care, but you’re mainly contributing data rather than receiving a new treatment.
Tianjin, Tianjin MunicipalityAges Any age - NCT04646187Enrolling by invitationPhase 4
Lowering biologic doses for Crohn’s and ulcerative colitis
This trial tests whether people with Crohn’s disease or ulcerative colitis who are currently well-controlled can safely use less-frequent anti-TNF medicine. It may help reduce treatment intensity while keeping inflammation under control.
GhentAges 12–25 - NCT04584632Recruiting
Stent-like device for blocked leg arteries in the thigh or knee
This trial studies a new stent-like vascular scaffold to improve blood flow in people with symptomatic blockage in the thigh/knee artery. It may help reduce symptoms from narrowed or blocked arteries, but you must meet several artery and health requirements.
Sydney, New South WalesAges Any age - NCT04536103Recruiting
Accelerated MRI scans after ACL knee injury surgery
This trial tests a faster MRI scan method to measure healing in the knee after an ACL (anterior cruciate ligament) tear and reconstruction. It may help researchers compare scan quality while participants go through standard rehab.
Cleveland, OhioAges 18–50
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Common questions
- Are there clinical trials for disease?
- Yes. Clin2 currently lists 9,353 recruiting disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.