Clinical trials
Disease clinical trials
Below are recruiting disease clinical trials, each written for real people, not researchers. We’re tracking 9,353 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04104659Enrolling by invitation
Tau PET scan study to map brain changes in Alzheimer’s
This study tests a PET scan “tracer” medicine called [18F]MK-6240 to see how tau protein changes show up in the brain. It may help researchers measure disease-related brain changes in people with normal thinking or mild dementia.
St Louis, MissouriAges 18 years+ - NCT04106830Recruiting
Study to follow neuroinflammation and demyelination diseases with imaging
This study builds a China-based group of people with neuroinflammatory and demyelination diseases and collects health and MRI (brain scan) information. It may help doctors better understand these conditions over time and improve future treatments.
Beijing, Beijing MunicipalityAges 16–75 - NCT01499394Recruiting
Biorepository study for adults who can consent
This study collects and stores samples (such as tissue or other biological materials) for future research. It mainly seeks adults who can agree to participate after understanding what it involves.
Mobile, AlabamaAges 18 years+ - NCT03995238Recruiting
Gait training for veterans with leg amputations
This study tests a walking rehabilitation plan to improve how you walk after a lower-leg amputation. It may help if your walking steps are uneven and you have diabetes and/or circulation problems in your legs.
Aurora, ColoradoAges 40–89 - NCT04008368RecruitingPhase 1/Phase 2
Second stem cell transplant for sickle cell with declining donor cells
This Phase 1/2 study tests whether repeating a stem cell transplant can help people with sickle cell disease (SCD) whose donor cells are no longer holding strong. It may help restore healthier blood cell production and reduce symptoms such as pain crises and severe anemia.
Bethesda, MarylandAges 2–80 - NCT03952637RecruitingPhase 1/Phase 2
Gene therapy for GM1 disease with IV delivery
This early-stage study tests an IV gene therapy that delivers a working copy of an enzyme gene to help the body make beta-galactosidase in GM1 gangliosidosis. It may help slow or improve disease symptoms and looks closely at safety and how well the treatment works.
Bethesda, MarylandAges 6 months–12 years - NCT03949855RecruitingPhase 2
Belimumab plus rituximab for primary membranous nephropathy
This study tests whether adding belimumab to rituximab helps people with primary membranous nephropathy (a kidney disease) that has the right blood test marker and specific protein levels. The goal is to improve kidney outcomes and reduce disease activity while keeping treatment safe.
Birmingham, AlabamaAges 18–75 - NCT04003272Enrolling by invitation
Reverse shoulder implant study for severely damaged rotator cuff
This trial studies a specialized reverse shoulder implant system for people whose rotator cuff is badly damaged or who had a prior shoulder replacement that failed. It aims to reduce pain and improve function by improving how your shoulder works, especially when the rotator cuff can’t do its job.
Louisville, KentuckyAges 18 years+ - NCT04003311Enrolling by invitation
Follow-up for specific shoulder implant types and surgery
This study checks outcomes in people who already received certain Zimmer Biomet shoulder implant components using the correct surgical technique. It may help improve how these specific implants are used and monitored after surgery.
Boise, IdahoAges 18 years+ - NCT03994471RecruitingPhase 3
Testing a new peritoneal dialysis fluid for kidney failure
This Phase 3 trial studies how well a new peritoneal dialysis solution works and whether it is safe. It’s meant for adults with kidney failure who already do a specific type of at-home dialysis.
AalborgAges 18 years+ - NCT04024761RecruitingPhase 1
NK cell therapy for leukemia relapse after transplant
This Phase 1 study tests whether an infusion of special immune cells (NK cells) from a donor can help control leukemia or related blood cancers that come back or do not fully go away after a stem cell transplant. It also uses short chemotherapy to “make space” for the NK cells to work, and IL-2 to help them function.
Boston, MassachusettsAges 12 years+ - NCT03954899Recruiting
Melatonin test for brain health in older adults
This study tests whether taking 5 mg of melatonin can improve thinking and brain health over time in older adults with early, mild symptoms. You may help researchers learn which brain changes and measures improve with melatonin.
Iowa City, IowaAges 56–85 - NCT03970096RecruitingPhase 2
Reduce graft-versus-host disease after stem cell transplant
This Phase 2 study tests ways to lower the risk of graft-versus-host disease (GVHD), a serious complication after an allogeneic stem cell transplant from a matched donor. It is for people with acute leukemia or MDS who are going to receive intensive conditioning therapy, aiming to improve safety while keeping the transplant effective.
Tampa, FloridaAges 1–60 - NCT03979534Recruiting
Protecting Kidneys With a Low-Protein Diet
This study tests whether a step-by-step low-protein diet can help protect your kidneys if you have advanced chronic kidney disease (stages 4 or 5) or stage 3 that is getting worse quickly. The goal is to see if this diet approach can slow down kidney damage.
La FlècheAges 18 years+ - NCT03983603Recruiting
Plant stanols and asthma symptoms prevention
This trial tests whether eating plant stanols (a natural substance found in some foods) can help prevent asthma symptoms in people with stable allergic asthma. You would need to take a daily chew and avoid certain cholesterol-lowering products during the study.
Maastricht, LimburgAges 18–70 - NCT03888300Recruiting
Measuring the stickiness of lung mucus in breathing problems
This study measures how thick and stretchy (elastic) lung mucus is. It may help researchers better understand mucus in people with obstructive lung breathing problems.
BrusselsAges 18 years+ - NCT03895541Recruiting
Heart ultrasound stiffness test for elderly diastolic heart failure
This trial tests a new heart ultrasound method to measure stiffness in the heart muscle, which could help doctors diagnose a type of heart failure where the heart is stiff but still squeezes normally. It is for elderly patients with heart failure, and the findings might lead to a simpler and safer way to identify this condition.
ParisAges 18–100 - NCT04016181Enrolling by invitation
Study to categorize lung fibrosis types at a clinic
This study enrolls people who have interstitial lung disease and are seen at the Edinburgh lung fibrosis clinic. It aims to sort different underlying “types” of lung fibrosis so doctors can better understand and potentially guide care.
Ages 18–99 - NCT03976622Enrolling by invitation
Inflammation study in vitiligo and other skin conditions
This study looks at inflammation in people with vitiligo, psoriasis, atopic dermatitis, or alopecia areata. It aims to understand how these conditions compare, which may lead to better treatments.
Bordeaux, BordeauxAges 18–75 - NCT03965234RecruitingPhase 1/Phase 2
Lung infusion for colorectal cancer that has spread to the lungs
This trial tests a procedure where chemotherapy is delivered directly into the lungs during surgery to remove or destroy lung tumors. It aims to reduce the chance of cancer returning after surgery for people with colorectal cancer that has spread to the lungs.
Buffalo, New YorkAges 18 years+ - NCT04008173Enrolling by invitation
Survey study of acute heart attack symptoms
This study collects information about symptoms and experiences during acute coronary syndromes, which are sudden, serious heart events like heart attacks or unstable angina. It may help researchers understand patterns of care and symptoms to improve future treatment and support.
Bologna, BolognaAges 18 years+ - NCT04014803RecruitingPhase 4
Aspirin plus one blood thinner versus aspirin plus clopidogrel
This trial compares two common “blood thinner” combinations to prevent problems after a PCI procedure for complex blocked heart arteries. It may help your care team find which combination works better for people with higher-risk artery patterns.
SeoulAges 19–75 - NCT03997552Recruiting
Gum surgery options to help regenerate damaged gum bone
This trial compares two dental gum surgery approaches to see which better helps the gum and bone heal in people with periodontitis. It may help by improving the depth of gum pockets and supporting regrowth of damaged areas around teeth.
MurciaAges 18 years+ - NCT03855917RecruitingPhase 4
Short 4-week hepatitis C treatment for early liver disease
This trial tests whether a very short 4-week course of two hepatitis C drugs (sofosbuvir and glecaprevir-pibrentasvir) can cure hepatitis C in people with early-stage liver disease. The goal is to see if a shorter treatment works as well as longer ones.
Darlinghurst, New South WalesAges 18 years+
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Common questions
- Are there clinical trials for disease?
- Yes. Clin2 currently lists 9,353 recruiting disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.