Clinical trials
Disease clinical trials
Below are recruiting disease clinical trials, each written for real people, not researchers. We’re tracking 9,578 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04126018Recruiting
MRI scan comparison for certain leaking or narrowed heart valves
This trial studies how well different MRI images can assess heart valve problems—like leaking (regurgitation) or narrowing (stenosis). It may help doctors get clearer information, especially in people who may not respond well to cardiac resynchronization therapy (CRT).
Cleveland, OhioAges 18–90 - NCT04119908Recruiting
Test video microscopy to predict bleeding risk
This study uses special video imaging to try to predict when bleeding may happen in certain inherited bleeding disorders. It may help doctors better anticipate bleeding and guide safer care.
Lille, NordAges 18 years+ - NCT04123314RecruitingEarly Phase 1
Psilocybin study for depression in mild memory or early Alzheimer’s
This early-phase study tests whether psilocybin (a psychedelic substance) can help with depression in people who have mild memory problems or early Alzheimer’s. The trial also closely monitors safety, thinking changes, mood, and blood pressure before and after dosing.
Baltimore, MarylandAges 18–85 - NCT04124120Recruiting
Single vs multiple bypass grafts for women heart surgery
This study compares outcomes of using one bypass graft versus multiple bypass grafts during coronary artery bypass surgery in women. It aims to see which approach leads to better recovery and heart outcomes for eligible patients.
Los Angeles, CaliforniaAges 18 years+ - NCT04134572Recruiting
Registry for Ollier disease and Maffucci syndrome
This trial is a registry, which means it collects information about people with Ollier disease and Maffucci syndrome. It can help researchers better understand these conditions and plan future studies.
Bologna, Emilia-RomagnaAges Any age - NCT04141592Recruiting
Study immune and disease changes in fatty liver
This study looks at what drives non-alcoholic fatty liver disease and how it affects the body, including immune-related changes. You may be invited if you have confirmed fatty liver disease or, alternatively, if you are a healthy person with no liver disease.
London, Greater LondonAges 18 years+ - NCT04160429Recruiting
Biospecimen testing to measure chemicals during treatment
This trial collects small samples like blood, sweat, and saliva while you’re taking certain medicines. Researchers will analyze these samples to see if they can detect chemical levels, which may help improve monitoring for people with chronic or infection-related illnesses.
Duarte, CaliforniaAges 18 years+ - NCT04166526Recruiting
Brain and brain-vessel MRI study in kids with sickle cell
This study uses MRI scans to understand how the brain and blood vessels are affected in children with sickle cell disease, including before and after certain treatments. It also includes healthy children for comparison and may help improve future monitoring and care.
Boston, MassachusettsAges 8–18 - NCT04178408Recruiting
IBD family and neighborhood health registry study
This study builds a health registry for people with inflammatory bowel disease (IBD) and compares them with healthy family and neighborhood controls. It may help researchers better understand IBD in sub-Saharan African communities.
HarareAges Any age - NCT04190849Recruiting
Children’s liver fat disease registry in Europe
This is a registry study collecting information about children and teens with fatty liver disease that isn’t caused by alcohol. It aims to better understand this condition and may help future research and treatments.
MaastrichtAges Up to 18 years - NCT04190602Recruiting
Registry study for NeoChord artificial mitral valve chord
This study keeps track of people who had NeoChord treatment to help understand how well it works in everyday care. You may be included if you had a certain type of mitral valve leakage (regurgitation) and the procedure happened after 2016.
BonnAges 18 years+ - NCT04194372Recruiting
Health study of risk markers in people with metabolic conditions
This study looks at your health “risk profile” in a hospital group of people with metabolic conditions like diabetes, obesity, or metabolic syndrome. It mainly focuses on measuring factors to better understand who is at higher risk of health problems over time.
Boulogne-sur-MerAges 18 years+ - NCT04192825Recruiting
Crohn’s anal drainage care study
This trial studies different care and management approaches for people with Crohn’s disease who have an anal infection or drainage area and are planning a drainage procedure. It may help improve how care is planned around the drainage procedure and follow-up.
RennesAges 18 years+ - NCT04193475Recruiting
Uses computer learning to improve stress heart ultrasound
This study uses computer technology (“machine learning”) with stress echocardiogram images (a heart ultrasound done during stress) to improve how heart function is measured. If you are able to have a stress echocardiogram, you may be able to help test a better way to interpret the results.
CottinghamAges 20–89 - NCT04194619Recruiting
Study of pregnancy safety in women with rare blood-vessel diseases
This study looks at pregnancy and the early period after birth in women with rare diseases that affect blood vessels. It may help doctors understand risks and improve care for future pregnancies.
AngersAges 18–45 - NCT04196712Recruiting
Heart artery testing registry during coronary angiography
This trial is a registry that collects information from people undergoing an invasive heart artery test (coronary angiography). It helps researchers understand heart disease and outcomes in real-world patients.
Essen, North Rhine-WestphaliaAges Any age - NCT04217421RecruitingPhase 3
Allopurinol for newborns needing heart surgery with bypass
This trial tests whether the medicine allopurinol can protect the brain and heart in newborns with serious congenital heart disease who need heart surgery soon after birth. It may help reduce injury during and around surgery that uses a heart-lung machine (cardiopulmonary bypass).
GroningenAges Up to 1 month - NCT04218318Recruiting
Stopping light therapy early in newborns with blood breakdown
This study looks for a safe threshold to stop the “light therapy” (phototherapy) in newborns who have jaundice caused by blood cell breakdown (hemolytic disease). It may help some babies avoid unnecessary extra days of treatment while still staying safe.
MadinahAges 1 hour–2 weeks - NCT04220047Recruiting
Surgery changes for preventing irregular heart rhythms during bypass
This trial studies whether removing a small heart pouch area and a specific ligament during off-pump heart bypass surgery improves outcomes. It is meant for people having their first off-pump coronary bypass, without a history of atrial fibrillation.
BeijingAges 18–80 - NCT04224558RecruitingPhase 1/Phase 2
Stem cell transplant for hard-to-control Crohn’s disease
This early-phase study tests whether a stem cell transplant can improve Crohn’s disease in teens and young adults whose disease is active and not responding to standard medicines. It may help some people who are not doing well despite several prior treatments, but it also involves intensive study procedures and safety checks.
Los Angeles, CaliforniaAges 13–28 - NCT04228978Recruiting
Lifestyle weight-loss program for people with PAD to stay mobile
This trial tests whether a healthy-lifestyle weight-loss program can help people with peripheral artery disease (PAD) lose weight and prevent worsening mobility. You may be eligible if you have PAD based on specific leg blood-flow test results and a higher body weight.
Chicago, IllinoisAges 18 years+ - NCT04232982Recruiting
Cyclophotocoagulation during Boston keratoprosthesis eye surgery
This trial looks at whether a specific eye laser treatment done through the white of the eye (called transscleral cyclophotocoagulation) works well and is safe for people getting a Boston keratoprosthesis. It may help improve comfort and vision outcomes for selected patients needing this type of cornea/eye replacement surgery.
Montreal, QuebecAges 18–80 - NCT04236726Recruiting
Quality of life study for people with chronic breathing failure
This study looks at how chronic respiratory failure affects day-to-day quality of life. It enrolls people who use breathing support at home or in care, and may help clinicians understand what support works best for patients’ daily living.
LondonAges 18 years+ - NCT04243525Recruiting
Inflammatory bowel disease patient research registry
This study is a research registry that collects information from adults receiving care for inflammatory bowel disease at UPMC. It may help researchers better understand bowel disease and improve future treatments.
Pittsburgh, PennsylvaniaAges 18 years+
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Common questions
- Are there clinical trials for disease?
- Yes. Clin2 currently lists 9,578 recruiting disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.