Clinical trials
Disease clinical trials
Below are recruiting disease clinical trials, each written for real people, not researchers. We’re tracking 9,578 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05017142Recruiting
Pediatric brain inflammation registry for Swiss patients
This study is a registry that collects health information from children and teens in Switzerland diagnosed with certain inflammatory brain and spinal cord conditions. It helps researchers understand these illnesses better over time and may guide future treatments.
Aarau, Canton of AargauAges Up to 36 years - NCT05020106Recruiting
Tests Alzheimer’s core blood/brain markers to set diagnostic cutoffs
This study checks Alzheimer’s “core biomarkers” to find the best cut-off values for diagnosing Alzheimer’s disease and related conditions. It may help doctors more accurately tell Alzheimer’s, mild cognitive changes, and other causes of memory problems apart.
Beijing, Beijing MunicipalityAges 55–75 - NCT05021601Recruiting
Ablation method comparison for rheumatic valve and ongoing AF
This study compares two heart procedures—targeting one or both upper heart chambers versus only the left upper chamber—to treat people with ongoing atrial fibrillation caused by rheumatic mitral valve disease. It aims to see which approach works better and is safer for restoring normal rhythm.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05020626Recruiting
Uses brain MRI data to study Alzheimer’s disease diagnosis
This study uses brain MRI images to better understand how a protein called tau spreads in Alzheimer’s disease and related conditions. If you’re 55 or older and had an MRI close to your diagnosis, you may be eligible.
Hong Kong, ShatinAges 55 years+ - NCT05025254Recruiting
Online thinking tests for people with Parkinson’s disease
This study tests online “thinking” (cognitive) abilities in people with Parkinson’s disease. It may help researchers better understand how thinking changes over time and how tests can be done from home.
Montreal, QuebecAges 45–90 - NCT05025774Recruiting
Exercise program study for young heart, leukemia, and lung survivors
This study looks at how an exercise program affects fitness and lung function in young people who are survivors of certain conditions (heart transplant, leukemia, or lung disease from prematurity). The goal is to see whether exercise can improve breathing and overall physical function safely.
Minneapolis, MinnesotaAges 8–25 - NCT05026138Recruiting
Study of severe HPV disease and why it keeps coming back
This study follows people with severe or hard-to-treat HPV-related conditions (and some closely related partners/household contacts) to learn how the virus causes illness and how the immune system responds. It may help doctors better predict who will develop severe disease and guide future treatments.
Bethesda, MarylandAges 3–100 - NCT05039411RecruitingPhase 1
Cord stem cell treatment for Crohn’s perianal fistulas
This Phase 1 study tests whether donor umbilical cord stem cells are safe for treating fistulas (abnormal tunnels) near the anus in people with Crohn’s disease. It’s mainly looking at safety, and it may help some people’s symptoms if the approach is workable.
Kuala LumpurAges 18 years+ - NCT05040464RecruitingPhase 3
Azathioprine or methotrexate added to adalimumab for Crohn’s
This trial compares two medicine options (azathioprine vs methotrexate) when added to adalimumab to treat active Crohn’s disease. It may help determine which add-on works better for people whose Crohn’s is still active despite standard treatments or who can’t take them.
AmiensAges 18 years+ - NCT05043870RecruitingPhase 4
Testing medicines that calm the immune system in kids with Crohn’s
This trial studies a combination of immune-suppressing treatments for children with Crohn’s disease that is not well controlled. It may help reduce inflammation and improve symptoms if you meet the study’s disease-activity and safety requirements.
Shanghai, Shanghai MunicipalityAges 6–18 - NCT05056740Recruiting
Inflammatory markers for CNS autoimmune disease diagnosis
This trial studies whether certain inflammatory biomarkers in blood and spinal fluid can help diagnose autoimmune diseases affecting the brain and spinal cord. It may help people who are undergoing testing for white matter lesions.
NiceAges Any age - NCT05059158Recruiting
Study how the brain clears amyloid in Alzheimer’s
This trial studies how the brain removes amyloid-β, a protein linked to Alzheimer’s disease. It may help researchers understand what’s happening in people with mild memory impairment or Alzheimer’s, and guide better treatments in the future.
München, BavariaAges 50–85 - NCT05065372RecruitingPhase 1
Metformin test with automated insulin in teens with type 1
This Phase 1 study tests how adding metformin affects blood flow in the kidneys, insulin sensitivity, and overall heart/metabolic health in young people with type 1 diabetes. It may help researchers understand whether this combo is safe and beneficial alongside automated or pump/shot insulin care.
Aurora, ColoradoAges 12–25 - NCT05067764Recruiting
Aponeurectomy for reducing Dupuytren’s disease return rate
This study looks at whether a specific hand/cord procedure called aponeurectomy can lower how often Dupuytren’s disease comes back within 2 years. You might be offered surgery and then followed to see how well your symptoms and tightness improve and how often they return.
PessacAges 18 years+ - NCT05067868RecruitingPhase 4
Replagal for Fabry disease in children and adults in India
This trial studies Replagal (enzyme replacement therapy) for people with Fabry disease who have not used it before. It aims to see how the treatment works and how safely it can be used in children and adults.
KolkataAges Any age - NCT05070013Recruiting
Brain stimulation to improve sleep in people with Parkinson’s disease
This study tests an adaptive brain stimulation device to help restore better sleep in people with Parkinson’s disease. You may be eligible if your Parkinson’s motor symptoms are severe despite best medical treatment and you are already being considered for a specific deep brain stimulation surgery.
Omaha, NebraskaAges 18–80 - NCT05077579Recruiting
Alzheimer’s scan study for people with higher body weight
This study uses brain scans (MRI and two special PET scans) to see how Alzheimer’s-related changes show up in people who are overweight or obese, with different blood-sugar and insulin patterns. It may help researchers understand whether body weight and metabolism affect early Alzheimer’s markers in the brain.
St Louis, MissouriAges 40–60 - NCT05077618Recruiting
Teeth bacteria study in seniors with and without Alzheimer’s
This study looks at the bacteria in the mouth (periodontal microbiota) to see whether they differ between seniors with Alzheimer’s disease and seniors without it. You may be asked for a sample from your gums/teeth and background health information.
Nice, CHU de NICEAges 18–90 - NCT05078814Recruiting
Survey of a heart and leg condition’s gene differences
This study collects information to understand how often certain genetic variants (ALDH gene family) show up in people with blocked leg arteries or an acute heart condition. The results may help researchers better understand the biology behind these illnesses.
TainanAges 20 years+ - NCT05089227RecruitingPhase 2
Long-term apixaban to prevent clots in autoimmune hemolytic anemia
This Phase 2 trial tests whether taking long-term apixaban (a blood thinner) can prevent venous blood clots in people with autoimmune hemolytic anemia (AIHA). It may help reduce the risk of dangerous clotting events if you meet safety and risk criteria.
DijonAges 18 years+ - NCT05093335RecruitingEarly Phase 1
PET scan test for CXCR4 in many relapsed cancers
This early study tests a new PET scan tracer (a radioactive imaging agent) that may light up a cell marker called CXCR4 in certain blood and solid tumor cancers. It may help doctors see where cancers are and how much CXCR4 they have, which could guide future treatments.
New York, New YorkAges 18 years+ - NCT05099874Recruiting
Computer training to improve attention in sickle cell disease
This trial tests whether a computer-based “attention control” training program can improve attention and daily functioning in children with sickle cell disease. To join, you must meet certain criteria and also pass an initial attention screening test during the study.
Washington D.C., District of ColumbiaAges 8–16 - NCT05112549RecruitingPhase 1
PD-1 antibody placed into brain fluid for metastatic cancer
This early-phase study tests a PD-1 antibody delivered directly into the brain fluid (intrathecal space) to treat metastatic solid tumors that have spread to the lining around the brain/spinal cord (leptomeningeal disease). It aims to see whether this approach can better control cancer in that area and whether it’s safe.
BonnAges 18 years+ - NCT05113095Recruiting
Survey of Darvadstrocel in Crohn’s with fistulas
This is a survey study in people with Crohn’s disease who have complex perianal fistulas and have already received Darvadstrocel. It aims to understand how patients are doing after treatment and gather real-world feedback.
Tokyo, TokyoAges 20 years+
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Common questions
- Are there clinical trials for disease?
- Yes. Clin2 currently lists 9,578 recruiting disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.