Clinical trials · Denver, CO
Down Syndrome clinical trials in Denver
We’re tracking 96 recruiting down syndrome studies with a site in or near Denver — including Phase 1, Phase 1/Phase 2, Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies near Denver
- NCT03215836Recruiting
Study obesity and metabolism in adults with asthma
This study looks at how weight and blood-sugar/fat changes in the body may affect the airways in people with asthma. You may be asked to complete breathing tests and possibly an airway procedure (bronchoscopy) to help researchers compare groups.
Aurora, ColoradoAges 18–65 - NCT06582914Recruiting
Lynch syndrome genetics and health study
This study looks at the genetics and health of people with Lynch syndrome, a condition that raises the risk for certain cancers. Researchers want to learn more about how different genetic changes affect health over time.
Aurora, ColoradoAges 18 years+ - NCT06840496RecruitingPhase 3
Study of oral NA-921 vs placebo for girls and women with Rett syndrome
This trial tests an oral medication called NA-921 in females with Rett syndrome to see if it works better than a placebo. It may be an option for those who have a confirmed MECP2 gene mutation and stable seizure patterns.
Aurora, ColoradoAges 5–20 - NCT07304024RecruitingPhase 1/Phase 2
Testing a drug and sound therapy for age-related hearing difficulty
This trial tests whether a combination of an antihistamine (clemastine fumarate) and specially designed sounds can improve how the brain processes hearing in middle-aged adults with mild hearing loss. It might help if you have trouble understanding speech in noisy settings.
Aurora, ColoradoAges 45–65 - NCT05932589Recruiting
Study of brain signals as signs of Rett syndrome
This study measures brain and nerve activity (brain signals) to find patterns that match Rett syndrome. It may help researchers better track Rett changes over time and develop more precise ways to measure response in future treatments.
Aurora, ColoradoAges 1–18 - NCT07450664Enrolling by invitation
Observational study of VYKAT XR for Prader-Willi syndrome
This study follows people with Prader-Willi syndrome who are already taking or starting VYKAT XR, including those switching from an earlier version of the drug (DCCR). It aims to understand how the treatment works in everyday life.
Aurora, ColoradoAges 4 years+ - NCT05819853RecruitingPhase 3
Semaglutide to help restart periods in PCOS
This Phase 3 study tests whether semaglutide can help people with polycystic ovary syndrome (PCOS) start ovulating and having more regular periods. You may join with or without metformin, and contraception rules are important because the medicine must not be used during pregnancy.
Aurora, ColoradoAges 12–35 - NCT06056908Recruiting
Shwachman Diamond Syndrome Registry and Study
This study is creating a registry for people with Shwachman-Diamond Syndrome (SDS) or similar conditions, and their family members. It aims to learn more about the condition and improve care by collecting health information over time.
Aurora, ColoradoAges Any age - NCT06366464RecruitingPhase 3
Study of a drug for sleepiness in Prader-Willi syndrome
This trial tests a medication called pitolisant to see if it helps reduce excessive daytime sleepiness in people with Prader-Willi syndrome. You or your loved one may be able to join if they have a confirmed diagnosis and a caregiver who can regularly help with study tasks.
Aurora, ColoradoAges 6 years+ - NCT07579429RecruitingPhase 2
Nicotinamide Riboside Supplement for MDS
This trial tests whether a supplement called nicotinamide riboside can help people with a blood disorder called MDS (myelodysplastic syndrome) or early warning signs of it. The supplement is meant to support your bone marrow's ability to make healthy blood cells.
Aurora, ColoradoAges 18 years+ - NCT06414096RecruitingPhase 1
Can a fertility drug help women with obesity get pregnant?
This study tests if a special way of giving a fertility drug (FSH) can improve pregnancy chances in women with obesity who are having trouble conceiving. It aims to understand how the drug affects reproductive health.
Aurora, ColoradoAges 19–37 - NCT07598643RecruitingPhase 2
Immune System Treatment to Help Down Syndrome Development
This study tests a medication called tofacitinib that modulates the immune system in children and young adults with Down syndrome aged 6–22 years. The goal is to see if it can improve brain development and overall health outcomes over 6 months.
Aurora, ColoradoAges 6–22 - NCT07221851RecruitingPhase 3
Weekly vs daily growth hormone for short stature in children
This trial tests a weekly growth hormone injection (lonapegsomatropin) compared to the standard daily growth hormone shot in children with short stature due to certain conditions. It aims to see if the weekly shot works as well or better and is safe.
Aurora, ColoradoAges 2–17 - NCT06668805RecruitingPhase 2
Testing vosoritide for children with Noonan syndrome and slow growth
This study tests a medication called vosoritide for children with Noonan syndrome who are still growing slowly despite using human growth hormone. The goal is to see if vosoritide can help them grow taller.
Aurora, ColoradoAges 3–11 - NCT06789913RecruitingPhase 2
Testing RLY-2608 for growth disorders linked to PIK3CA mutations
This trial tests a new medicine, RLY-2608, that targets the specific genetic change (PIK3CA mutation) causing overgrowth conditions. It aims to see if the drug can slow or stop the growth of affected tissues.
Aurora, ColoradoAges 2 years+ - NCT05978141Recruiting
T-cell lymphoma registry study
This study creates a registry for people with certain T-cell or NK-cell lymphomas. It collects health information and tumor samples to learn more about these diseases and improve future treatments.
Aurora, ColoradoAges Any age - NCT07135050RecruitingPhase 1/Phase 2
Gene therapy study for Pitt Hopkins syndrome
This trial tests a new gene therapy called MZ-1866 for people with Pitt Hopkins syndrome. The therapy is given as a single injection into the fluid around the brain to help replace the missing or faulty TCF4 gene.
Aurora, ColoradoAges 2–25 - NCT07209462RecruitingPhase 2
MRM-3379 for Fragile X Syndrome in males
This trial tests an investigational medicine called MRM-3379 in males with Fragile X syndrome. It looks at how the medicine affects thinking and behavior over time.
Aurora, ColoradoAges 13–45 - NCT02012699Recruiting
Cancer registry for people with or at risk of cancer
This trial collects health information and samples (a “cancer repository”) to help researchers study cancer and cancer risk. You may be able to join if you’ve had cancer before or if you’re at higher risk or have concerning findings.
Greenwood Village, ColoradoAges 19–110 - NCT06633120Recruiting
Growing eggs in the lab for women with PCOS
This study tests a way to mature eggs outside the body for women with PCOS or high ovarian reserve. It might help avoid side effects from fertility medications.
Lone Tree, ColoradoAges Up to 38 years - NCT06471374Recruiting
Circadian rhythm in delayed sleep-wake phase disorder
This study looks at how your body's internal clock works in people with delayed sleep-wake phase disorder, especially those living at high altitudes. It aims to understand the causes of this sleep problem and may help find better treatments.
Boulder, ColoradoAges 16–40 - NCT07646782Recruiting
Human Observatory Study: Aging and Longevity Research
This study observes how people age over time to better understand what helps people live longer and healthier lives. You'll share health information through surveys or online screening, and researchers will track changes in your health and wellbeing.
Boulder, ColoradoAges 18 years+ - NCT07669168Recruiting
Health study comparing usual care vs. extra support
This study looks at whether adding extra health support helps people stay healthier over time. You would be followed for a while and asked to share how you are doing.
Boulder, ColoradoAges 18 years+ - NCT07563777Recruiting
Long-term study of human aging and health
This is a long-term research study that follows people over time to understand how humans age. Researchers will collect information about your health and lifestyle to learn what helps people stay healthier as they get older.
Boulder, ColoradoAges 18 years+
Hear when a new Down Syndrome trial opens near Denver, CO
We’ll email you when one opens near Denver, CO — at most once a week, no account needed, unsubscribe anytime.
Down Syndrome trials in other cities
Where these studies are running near Denver
Institutions with a site for the recruiting down syndrome studies listed above.
- Children's Hospital Colorado · 8 studies
- University of Colorado Anschutz Medical Campus · 6 studies
- Longevity Metrics · 3 studies
- Advent Health
- Ascendis Pharma Investigational Site
- Biomed Testing Facility
- Colorado Center for Reproductive Medicine
- Neurocrine Clinical Site
What taking part in a down syndrome study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting down syndrome studies in Colorado.
Common questions
- Are there down syndrome clinical trials near Denver?
- Yes. We're currently tracking 96 recruiting down syndrome studies with a site near Denver, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a down syndrome study near Denver?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Denver to take part?
- Not necessarily. These studies have a site near Denver, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New down syndrome studies open near Denver regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.