Clinical trials · Ohio
Down Syndrome clinical trials in Ohio
We’re tracking 156 recruiting down syndrome studies with a site in Ohio — including Phase 1, Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in Ohio
- NCT04165109Recruiting
Down syndrome study to test memory and thinking changes
This study enrolls adults with Down syndrome to better understand how thinking and memory develop and change over time. It may help by building a “trial-ready” group and by measuring thinking in a careful, consistent way.
Beachwood, OhioAges 25–55 - NCT02890485Recruiting
Dry needling for knee pain with stair or squat pain
This study tests whether dry needling can reduce ongoing knee pain in people who feel pain around the kneecap when going up or down stairs, squatting, or running. You may be able to join if your knee pain has lasted at least 3 months and you’re referred to physical therapy.
Columbus, OhioAges 18–40 - NCT00900198Recruiting
Give cancer tissue samples to help future cancer research
This study collects tissue or other cancer-related samples to help researchers better understand cancer and develop better tests or treatments. You can join if you are being evaluated for or treated for cancer, and you agree to let your samples be used for research.
Columbus, OhioAges 2 months+ - NCT07210515RecruitingPhase 3
Testing Ambros Therapy for Early CRPS
This trial tests if an intravenous medicine called AMBTX-01 (neridronate) can help people with early-stage Complex Regional Pain Syndrome (CRPS) type 1. It focuses on those whose affected limb feels warm, looks red, and is swollen.
Cleveland, OhioAges 18 years+ - NCT04792463Recruiting
BAP1 gene cancer-risk study and family cancer patterns
This study looks at how the BAP1 gene affects cancer risk and what cancers people develop, including within families. You may be able to join if you have a known BAP1-related mutation, a strong family cancer history, or a concerning cancer pattern linked to BAP1.
Columbus, OhioAges Any age - NCT04669548Recruiting
Accuryn monitoring study for people having heart surgery
This registry collects information from patients who are monitored with the Accuryn system during heart surgery and their ICU stay. It helps researchers learn from the system’s signals to better understand patient care around cardiac procedures.
Cleveland, OhioAges 18 years+ - NCT07791966Recruiting
Brain stimulation for chronic pain
This study tests a non-invasive brain stimulation technique to help people with chronic pain, specifically Complex Regional Pain Syndrome (CRPS), manage pain-related avoidance behaviors. It may help reduce pain and improve daily function.
Cleveland, OhioAges 18 years+ - NCT07720323Recruiting
Can a wristband help with long-term nausea and vomiting?
This study tests if a special wristband (EmeTerm) can reduce nausea and vomiting symptoms in people who have had these problems for more than two months. You will use the band and report your symptoms through online surveys.
Columbus, OhioAges 18 years+ - NCT07695298RecruitingPhase 4
Testing faricimab for a rare eye disease linked to histoplasmosis
This trial tests a drug called faricimab (brand name Vabysmo) for treating abnormal blood vessel growth in the back of the eye, caused by a past infection with histoplasmosis. The goal is to see if it helps improve vision over 52 weeks.
Cincinnati, OhioAges 18 years+ - NCT03001180Recruiting
Study blood and tissue markers in vascular anomalies
This study collects extra blood (and sometimes tissue during procedures) to look for markers that can help doctors better understand vascular anomalies. It may not be a treatment, but it can improve future care by finding patterns linked to the condition.
Cincinnati, OhioAges 1 day+ - NCT06034275RecruitingPhase 1
Study of VIP943 for CD123-positive blood cancers
This trial tests a new drug called VIP943 for people with advanced acute myeloid leukemia (AML), B-cell acute lymphoblastic leukemia (B-ALL), or myelodysplastic syndrome (MDS) whose cancer cells have a marker called CD123. It is for those who have tried all other treatments or cannot receive them.
Cincinnati, OhioAges 18 years+ - NCT07558265Recruiting
Comparing breathing support methods in the emergency department
This study tests two common ways to help people who are having trouble breathing in the emergency room: a face mask that pushes air into the lungs (non-invasive positive pressure ventilation) or high-flow oxygen through small tubes in the nose (high-flow nasal oxygen). The goal is to find which method works better to avoid needing a breathing tube.
Columbus, OhioAges 18 years+ - NCT07542834Recruiting
Virtual Reality Training for Medical Students
This study tests whether using virtual reality can help medical students learn better and feel more confident in their training. Researchers will compare how students learn with VR versus traditional methods.
Athens, OhioAges 18 years+ - NCT07490444RecruitingPhase 2
Better glasses for children with Down syndrome
This trial tests a new way to make eyeglass prescriptions for children with Down syndrome, ages 5 to 12. The goal is to see if it improves their vision.
Columbus, OhioAges 5–12 - NCT07444567RecruitingPhase 3
Continuing benralizumab treatment after a previous study
This trial lets people who completed an earlier benralizumab study and are benefiting from the medicine keep receiving it. The goal is to provide ongoing access while we continue to monitor safety and effectiveness.
Cleveland, OhioAges 6 years+ - NCT07335523Recruiting
Testing for poor digestion in Alagille syndrome after liver transplant
This study looks for signs of poor digestion after a liver transplant in people with Alagille syndrome. You collect stool samples for 3 days while on a high-fat diet to see if your pancreas is making enough enzymes.
Cincinnati, OhioAges 7–50 - NCT05386173Recruiting
Tests fetal aortic valve balloon surgery for severe narrowing
This trial studies whether doing a procedure before birth to open a baby’s aortic valve improves outcomes. It compares this approach in a specific group of pregnancies with severe heart flow problems seen on ultrasound.
Columbus, OhioAges 5 months–7 months - NCT07221851RecruitingPhase 3
Weekly vs daily growth hormone for short stature in children
This trial tests a weekly growth hormone injection (lonapegsomatropin) compared to the standard daily growth hormone shot in children with short stature due to certain conditions. It aims to see if the weekly shot works as well or better and is safe.
Cincinnati, OhioAges 2–17 - NCT07220382RecruitingPhase 4
Botox injections before large hernia surgery
This trial tests if getting Botox shots in the belly muscles before hernia surgery makes the repair easier and more successful. It is for adults who need a planned, open surgery for a large ventral hernia.
Cleveland, OhioAges 18 years+ - NCT07117032RecruitingPhase 1
Radiation therapy for cancer-related stomach pain
This trial tests a type of radiation therapy (SBRT) to treat severe stomach pain caused by cancer pressing on nerves near the stomach. It aims to provide pain relief without the need for a standard nerve block procedure.
Cleveland, OhioAges 18 years+ - NCT07096297RecruitingPhase 2
Testing two drugs for lower-risk MDS
This trial is testing whether a combination of two drugs, luspatercept and darbepoetin alfa, can help people with lower-risk myelodysplastic syndromes (MDS) who need frequent red blood cell transfusions. The goal is to see if the combination reduces their need for transfusions.
Columbus, OhioAges 18 years+ - NCT07087587Recruiting
Sleep apnea treatment for AFib: a personalized trial
This study tests whether treating sleep apnea with a CPAP machine can reduce the number of AFib episodes you have. It's a personalized 'N-of-1' trial, meaning you'll try both CPAP and no CPAP at different times to see what works best for you.
Cleveland, OhioAges 18–85 - NCT06991400Recruiting
A study of a new surgical approach for TTTS and TAPS
This trial tests a new surgical technique for twin-to-twin transfusion syndrome (TTTS) or twin anemia-polycythemia sequence (TAPS). It places a stitch through the amniotic sac during surgery to see if it helps. The study is for pregnant people between 18 and 23 weeks with healthy cervical length and a safe access point for surgery.
Cincinnati, OhioAges 18 years+ - NCT07038200RecruitingPhase 3
Study of Del-brax (AOC 1020) for People with FSHD
This study tests an experimental medicine called Del-brax (AOC 1020) for people with facioscapulohumeral muscular dystrophy (FSHD). The goal is to see if it can help improve muscle strength and slow the disease. You may be able to join if you have a confirmed FSHD diagnosis and can walk at least 10 meters on your own.
Columbus, OhioAges 16–70
Down Syndrome trials by city in Ohio
Where these studies are running in Ohio
Institutions with a site for the recruiting down syndrome studies listed above.
- The Ohio State University · 6 studies
- Cincinnati Children's Hospital Medical Center · 3 studies
- Cleveland Clinic · 3 studies
- University of Cincinnati · 2 studies
- Ambros Clinical Trial Site
- Ascendis Pharma Investigational Site
- Case Western Reserve University
- Cincinnati Eye Institute
What taking part in a down syndrome study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Down Syndrome trials in other states
Common questions
- Are there down syndrome clinical trials in Ohio?
- Yes. We're currently tracking 156 recruiting down syndrome studies with a site in Ohio, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a down syndrome study in Ohio?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Ohio to take part?
- Not necessarily. These studies have a site in Ohio, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New down syndrome studies open in Ohio regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.