Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,196 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06863207Recruiting
Testing a new treatment for teens with stomach and nerve problems
This study tests whether a personalized nerve stimulation treatment can help teens with cyclic vomiting syndrome or functional dyspepsia who also have symptoms of autonomic dysfunction, like dizziness, fatigue, or heart palpitations when standing.
Milwaukee, WisconsinAges 11–18 - NCT06864156Recruiting
Molecules and vitamin levels in long COVID with brain fog
This study looks at certain molecules (called microRNAs) and vitamin B12 levels in people who have ongoing brain-related symptoms like depression, anxiety, or fatigue after a COVID-19 infection. It may help understand why some people have long-lasting symptoms and could lead to better treatments.
Mexico City, Mexico CityAges 18–65 - NCT06866106Recruiting
Well-being in IBS: A phone program for strengths and happiness
This study tests a program that helps people with IBS focus on their strengths and happiness through phone sessions. It aims to see if this approach can improve well-being and manage IBS symptoms.
Boston, MassachusettsAges 18 years+ - NCT06868979Recruiting
Eye imaging for X-linked disorders
This study uses special eye imaging to look at changes in the brain and eyes of people with creatine transporter deficiency (a condition that affects brain energy) or fragile X syndrome. It aims to find a way to see these brain changes without needing a biopsy or spinal tap.
BronAges 5–60 - NCT06871293Recruiting
Long Covid recovery: rehab with coaching
This study tests a program of rehab exercises and memory/thinking activities, along with coaching messages, to help people with Long Covid feel better and function in daily life. You may qualify if you had Covid, have high blood pressure or diabetes, and still have symptoms like fatigue or trouble thinking for at least 4 weeks.
Bogotá, Bogotá DCAges 18–80 - NCT06874478Recruiting
Breathing help for babies born by planned C-section
This study looks at whether giving steroids before a planned C-section at full term can help babies breathe better after birth. It may be an option for pregnant women who are scheduled for a C-section and meet certain health criteria.
AsyutAges 20–39 - NCT06876415Recruiting
Comparing two ways to wean patients off ECMO
This study compares two methods for removing patients from a breathing machine called ECMO. It aims to find which approach works better and is safer.
LyonAges 18 years+ - NCT06879743Recruiting
Gentle neck release for fibromyalgia pain
This study tests whether a gentle hands-on technique called suboccipital release can help ease fibromyalgia pain. It’s for women aged 20–45 with a stable fibromyalgia diagnosis who do not have certain other conditions or use strong pain medications.
CairoAges 20–45 - NCT06883513Recruiting
Osteopathic therapy for long COVID symptoms
This trial tests if gentle hands-on treatment (osteopathic manipulative therapy) can help relieve long-lasting COVID symptoms like fatigue, brain fog, and body pain.
Louisville, KentuckyAges 18 years+ - NCT06886425Recruiting
Study of how azacytidine works in blood cancers
This study looks at how certain enzymes in your body affect the way a drug called azacytidine works against blood cancers like acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS). The goal is to better understand who might benefit most from this treatment.
MarseilleAges 18 years+ - NCT06888024Recruiting
Measuring pelvic vein blood flow with MRI
This study uses MRI scans to measure blood flow in the pelvic veins. It’s for people who either have no vein problems, or have symptoms of a compressed left iliac vein, or already have a stent in that vein. The goal is to learn more about how blood flows in these conditions.
Worcester, MassachusettsAges 18–89 - NCT06889454Recruiting
Heart and blood vessel changes in women with PCOS after treatment
This trial looks at how the heart's blood vessels and certain markers change in women with PCOS when they drink a sugary solution (OGTT). It checks these markers before treatment starts and again 6 and 12 months after, to help understand cardiovascular risk in PCOS.
ChaïdáriAges 18–45 - NCT06889974Recruiting
Timing of kidney treatment in tumor lysis syndrome
This study looks at when to start kidney dialysis for patients in the ICU who develop tumor lysis syndrome (a rapid breakdown of cancer cells after chemotherapy that can harm the kidneys). It aims to find the best timing for this treatment.
AngersAges 18 years+ - NCT06892223RecruitingPhase 2
Anti-NKG2A antibody for leukemia or MDS after half-matched transplant
This trial tests a drug that targets NKG2A, a protein that may help prevent cancer cells from hiding from the immune system. It is for people with acute myeloid leukemia (AML), myelodysplastic syndrome (MDS), or related conditions who have already received a half-matched stem cell transplant (haploidentical transplant) with a specific anti-rejection drug plan.
Genova, GENOVAAges 18–99 - NCT06892275Recruiting
Helping high-risk women decide about breast MRI
This study tests a decision aid to help women at high risk for breast cancer decide whether to get a screening MRI. It is designed for Black and Latina women who have had a normal mammogram in the past year.
Washington D.C., District of ColumbiaAges 18–74 - NCT06896448Recruiting
Sleep apnea screening for head and neck cancer patients
This study tests a smartphone app (Apneal) to screen for sleep apnea in people who are being checked for head and neck cancer. It aims to find sleep problems early so they can be treated.
Caen, FranceAges 18 years+ - NCT06904482RecruitingPhase 2
Stem cell transplant with half-matched donor and cord blood
This trial tests a new way to do a stem cell transplant for people with hard-to-treat blood cancers. It combines a half-matched family donor (haploidentical) with a cord blood unit to help the transplant work better.
Cleveland, OhioAges 18 years+ - NCT06898996Recruiting
Stool test study for Lynch syndrome colon screening
This trial tests a new stool-based test (FIT) to see if it can help find colon cancer early in people with Lynch syndrome. You will collect stool samples at home and complete surveys before your regular colonoscopy.
Chicago, IllinoisAges 20–80 - NCT06899685Recruiting
Kinesio taping vs. tool-assisted massage for neck pain relief
This study compares two non-invasive treatments for neck pain caused by muscle knots in the upper trapezius (the muscle between your neck and shoulder). The goal is to see which approach better reduces pain, improves neck movement, and helps with daily function.
Banī SuwayfAges 19–23 - NCT06901245RecruitingPhase 4
Tirzepatide for young adults with obesity
This study tests the diabetes/weight-loss drug tirzepatide (Mounjaro) in young adults aged 18–26 who have obesity and either Prader-Willi syndrome, hypothalamic obesity, or general obesity. It looks at whether a weekly injection can help with weight management.
Saint Paul, MinnesotaAges 18–26 - NCT06903026Recruiting
Memory loss and sleep apnea: a study
This study looks at whether people who have had a specific kind of temporary memory loss (transient global amnesia) also have sleep apnea. If you fit, your past medical data may be used to help find a link.
StrasbourgAges 18 years+ - NCT06903559RecruitingPhase 1/Phase 2
Roxadustat for heart and nutrition in dialysis patients
This study tests whether roxadustat can help improve heart health, nutrition, and reduce inflammation in people on hemodialysis. It may offer a new treatment option for anemia related to kidney disease.
Al Mansurah, DakahliyaAges 18 years+ - NCT06903962Recruiting
Mind-body program for chronic arm or hand pain
This trial tests whether a mind-body program can help people with long-term pain in their upper arm, forearm, or hand that is not caused by a clear physical injury. It focuses on retraining how your brain responds to pain triggers.
Boston, MassachusettsAges 18–60 - NCT06906276Recruiting
Brain activity during walking in atypical Parkinson's
This study looks at brain activity while walking in people with atypical Parkinsonian syndromes like PSP or MSA. It may help understand how these conditions affect walking and balance.
Solna, SolnaAges Any age
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,196 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.