Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,055 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06377059Recruiting
Early detection of complications during immunotherapy
This trial uses special equipment to watch for early side effects in people getting CAR T-cell therapy or bispecific antibodies for blood cancers, like lymphoma. It aims to catch problems early so they can be treated faster.
Copenhagen OAges 18 years+ - NCT06366269Recruiting
Acupuncture first for bladder pain syndrome
This trial tests whether acupuncture can help relieve pain and pressure from bladder pain syndrome (also called interstitial cystitis). Researchers want to see if using acupuncture early can improve symptoms better than usual care.
Cleveland, OhioAges 18–89 - NCT06371300Recruiting
Red vs Blue Light for Dry Eye With Mites
This study tests whether a special light (photobiomodulation) using red or blue light can help people with dry eye that is caused by both blocked oil glands and tiny eyelash mites. You'd receive 3 treatments, and we'd check how your eyes feel for a month after.
AucklandAges 18 years+ - NCT06377462Recruiting
VEXAS syndrome registry with blood sample collection
This study creates a national registry for people with VEXAS syndrome to track the disease and collect blood samples for research. Joining helps doctors learn more about VEXAS so they can better diagnose and treat it in the future.
AachenAges 18 years+ - NCT06341673Recruiting
Nerve stimulation for bladder symptoms in multiple sclerosis
This trial tests a nerve stimulation treatment (TTNS) to improve bladder symptoms like urgency or frequent urination in people with multiple sclerosis. It is a randomized controlled study comparing this approach to a control, and aims to see if it can reduce bothersome bladder issues.
Khobar, Eastern ProvidenceAges 18 years+ - NCT06338488Recruiting
Dry needling for shoulder pain from muscle knots
This trial tests if dry needling (inserting thin needles into muscle knots) can reduce shoulder pain caused by a condition called myofascial pain syndrome. It may help if you have a specific muscle knot in your shoulder blade area and significant pain.
Kütahya, TürkiyeAges 18–80 - NCT06349538Enrolling by invitation
Essential tremor subtypes and progression markers study
This study looks for biological markers to better understand different types of essential tremor and how the condition changes over time. It may help identify who has which subtype and predict disease progression.
Graz, AustriaAges 18 years+ - NCT06347926Recruiting
Light therapy for menopause symptoms in breast cancer
This study tests a light-based treatment (photobiomodulation) to see if it improves sexual quality of life for women with breast cancer who have menopause-related vaginal symptoms that the usual moisturizers did not relieve.
Montpellier, HéraultAges 18 years+ - NCT06338514Recruiting
Dry needling for upper back muscle pain
This study tests if dry needling helps reduce shoulder pain caused by muscle knots in the upper back. It may be an option if you have not had recent back surgery or treatments.
KütahyaAges 18–80 - NCT06332859Recruiting
Resilience training for heart recovery
This study tests a resilience training program (a way to build mental strength and coping skills) for people recovering from certain heart conditions. It aims to help you feel better and manage stress, which is important for heart health.
Bad Tatzmannsdorf, BurgenlandAges 18 years+ - NCT06320782Enrolling by invitation
Diet and belly fat study for overweight adults
This study tests how different diets affect belly fat, thigh muscle, and heart health in people who are overweight. It might help you find a way to eat that improves your health.
Recife, PernambucoAges 20 years+ - NCT06334666Enrolling by invitation
Step counting for fatty liver disease management
This trial tests if using a pedometer to track daily steps can help people with a type of fatty liver disease (called MASLD) become more active and improve their health. It may be a good fit if you are not already very active and want to try a simple way to manage your condition.
Bangkoknoi, BangkokAges 18 years+ - NCT06327984Recruiting
Sex hormones and inflammation in heart disease
This study looks at how sex hormones and inflammation affect chest pain and heart disease. It aims to improve care for people with coronary artery disease.
LondonAges 16 years+ - NCT06312644Recruiting
Study of Ultomiris safety during pregnancy
This study looks at the safety of the medication Ultomiris when taken during pregnancy or breastfeeding. If you are pregnant and currently taking Ultomiris for an approved condition, this research will help gather information on how it affects you and your baby.
Boston, MassachusettsAges Any age - NCT06307535Recruiting
Meaning-centered therapy for cancer caregivers
This study tests a type of therapy that helps caregivers find meaning and cope with the stress of caring for someone with advanced cancer. It is done online, so you can join from home.
Miami, FloridaAges 18 years+ - NCT06315309RecruitingPhase 2
Two-step ATG to prevent GVHD after stem cell transplant
This trial tests a two-step use of ATG (a drug that calms immune cells) to help prevent graft-versus-host disease (GVHD) in patients receiving a stem cell transplant from a donor. It may be an option for people with certain blood cancers or disorders who are getting a strong, marrow-clearing transplant.
Birmingham, AlabamaAges 18–60 - NCT06315179Recruiting
Spatial gene study for inflammatory bowel disease
This study looks at tissue samples from people with suspected Crohn's disease, ulcerative colitis, or indeterminate colitis. The goal is to understand these conditions better and may lead to improved treatments.
Seattle, WashingtonAges 6–21 - NCT04694248Recruiting
Blood thinner plus antiplatelet after iliac vein stent
This trial looks at whether taking a blood thinner and an additional clot-prevention medicine (antiplatelet) after iliac vein stenting can improve treatment of certain deep vein clots. It may help prevent the clot from coming back or spreading, but it also increases bleeding risk, so careful eligibility screening is important.
Hangzhou, ZhejiangAges 18 years+ - NCT04110730Recruiting
Testing 3D-printed prostheses on hand and arm brain signals
This study looks at how 3D-printed prosthetic devices affect brain and nerve activity related to moving and using the upper limb. You might be able to join if you are a child or teen who is missing part of a hand/arm and has upper-limb movement difficulties.
Omaha, NebraskaAges 3–18 - NCT05587127Recruiting
CBT therapy for eating anxiety in functional stomach pain
This trial tests an “exposure-based” type of cognitive behavioral therapy (CBT) to help people with functional dyspepsia (stomach discomfort after eating) who avoid or restrict food. The goal is to reduce food fear and improve eating and weight, after other medical causes have been ruled out.
Boston, MassachusettsAges 18 years+ - NCT06283498Enrolling by invitation
Radiofrequency treatment for overactive bladder
This study tests a new non-surgical treatment for overactive bladder using radiofrequency energy delivered through the vagina to calm the nerves that cause urgency and leaking. It is for people who have urge incontinence and have not found relief from medication.
Corona del Mar, CaliforniaAges 21–80 - NCT06288672Recruiting
Skin patch test for food allergies in IBS
This study tests whether a skin patch can help identify food allergies in people with irritable bowel syndrome (IBS) whose symptoms are not well controlled. It involves avoiding certain foods and using patches on your back to see if you react.
North Wales, PennsylvaniaAges 18 years+ - NCT04615130Recruiting
Pulmonary rehab for symptoms after a lung blood clot
This trial studies a structured pulmonary (lung) rehabilitation program for people who still have breathing and activity problems after a pulmonary embolism (PE). It may help improve physical ability and function during recovery.
ViennaAges 18–90 - NCT06291389Recruiting
Airway pressure changes during tummy tuck surgery
This trial tests how changes in airway pressure during tummy tuck surgery affect breathing after the operation. It is for healthy adults having a tummy tuck with muscle tightening.
Tanta, EgyptAges 20–50
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,055 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.