Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,055 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06428019RecruitingPhase 3
Comparing drug combinations for untreated CLL or SLL
This trial tests two different drug combinations (venetoclax with obinutuzumab or with acalabrutinib) to see how they affect the risk of tumor lysis syndrome in people with untreated CLL or SLL. It may help find the safest and most effective way to start treatment.
Tucson, ArizonaAges 18 years+ - NCT04728516RecruitingPhase 4
Eradication treatment versus acid pills to prevent GI bleeding
This trial compares a “dual eradication therapy” (to get rid of H. pylori in the stomach) versus usual acid-reducing pills (PPIs) to lower the risk of gastrointestinal bleeding in people with recent heart artery disease treated with a stent. It may help by reducing stomach infection-related bleeding while you continue needed heart medicines.
Bozhou, AnhuiAges 18 years+ - NCT04759274Recruiting
Personalized water pill dosing support for kidney and fluid overload
This trial tests a decision-support tool to help your care team safely adjust water pills (“diuretics”) when you have kidney disease and fluid buildup. It may help reduce swelling by guiding dosing using your home weight and blood pressure.
Dallas, TexasAges 18 years+ - NCT06298864Recruiting
Online anxiety treatment after a heart attack
This study tests an online program to help people reduce anxiety after a heart attack or unstable angina. The goal is to see if the program can improve quality of life and reduce heart-related worries.
StockholmAges 18 years+ - NCT06399952Recruiting
Natural history study for Baker Gordon syndrome
This study follows people with Baker Gordon syndrome over time to better understand the condition. Participants and their caregivers share medical records and complete tests and questionnaires.
Columbia, MissouriAges birth–99 years - NCT06402318Recruiting
Quick breath test for COVID, flu, and RSV
This study tests a breathalyzer device that quickly detects COVID-19, flu, and RSV from your breath. If you are already being tested for these viruses, you may join to see if this new method works as well as the usual swab test.
Fort Sam Houston, TexasAges 18–89 - NCT06403189Recruiting
Studying choroid plexus function in brain diseases
This study looks at how a part of the brain called the choroid plexus works in people with different brain conditions. It may help find better ways to diagnose or treat these diseases.
ParisAges 18 years+ - NCT06419972Recruiting
Multimodal program for women in menopause transition
This study tests a program combining different therapies to help women during the menopause transition. It aims to improve symptoms and quality of life.
ValenciaAges 45–85 - NCT06408662Recruiting
Remote mindfulness program for tics (Tourette or tic disorder)
This study tests a mindfulness program delivered remotely (via phone or tablet) to help people with moderate to severe tics. It aims to see if mindfulness can reduce tic severity and improve quality of life.
Baltimore, MarylandAges 18 years+ - NCT06416488Recruiting
HIIT for heart health in school-age kids
This trial tests whether a high-intensity interval training (HIIT) program can improve heart health and reduce risk factors like high blood sugar, cholesterol, and blood pressure in school-age children. It's for children who have at least one of these problems and are not already doing intense exercise.
Shanghai, Shanghai MunicipalityAges 7–18 - NCT06414096RecruitingPhase 1
Pulsatile FSH study for women with obesity or low ovarian reserve
This study tests a new way to give a fertility hormone (FSH) in pulses through a small tube to see if it helps women with obesity or low egg reserve have better egg development with fewer health risks. It may improve fertility treatment outcomes for these women.
Aurora, ColoradoAges 19–37 - NCT06408402Recruiting
Environment and tumor risk in SDHx carriers
This study looks at whether things in the environment (like chemicals or lifestyle) affect the risk of developing certain tumors in people who have a change in their SDHx gene. It compares people with the gene change who have had a related tumor to those who haven't.
AngersAges 18 years+ - NCT03949972Recruiting
FSGS and MCD patient registry for kidney disease
This study is a registry that collects medical information from people with nephrotic syndrome caused by FSGS or minimal change disease (MCD). It may help doctors better understand these conditions and improve future care, especially by tracking patients over time.
Cologne, North Rhine-WestphaliaAges Any age - NCT06395285RecruitingPhase 1
Testing DF-003 for ROSAH syndrome with eye inflammation
This trial tests an oral medication called DF-003 for people with ROSAH syndrome who have eye inflammation (uveitis). The goal is to see if the drug is safe and tolerable. It might help reduce eye inflammation and other symptoms.
Bethesda, MarylandAges 18–65 - NCT06398457RecruitingEarly Phase 1
Darzalex Before Stem Cell Transplant for High-Risk Graft Failure
This trial tests giving a drug called Darzalex Faspro before the usual desensitization and a stem cell transplant for people at high risk of graft failure due to donor-specific antibodies. The goal is to prevent the transplant from failing.
Baltimore, MarylandAges 18 years+ - NCT06389474RecruitingPhase 3
Testing a new treatment for children with a serious kidney condition
This study tests a new medicine called INM004 in children with STEC-HUS, a serious illness that damages the kidneys and blood cells. It may help speed up recovery and prevent complications.
Bahía Blanca, Buenos AiresAges 9 months–17 years - NCT05372393Recruiting
Carpal tunnel surgery with local anesthesia, with or without nerve block
This study compares two ways of giving pain control during carpal tunnel release surgery: local anesthesia alone versus local anesthesia plus a targeted nerve block. It may help find the safest and most comfortable option for people having carpal tunnel surgery.
Kuopio, Northern SavoniaAges 18 years+ - NCT05975671Recruiting
Survey in pediatric ICU to reduce upfront vancomycin use
This study is a survey and quality-improvement effort in participating children’s intensive care units. It aims to understand and change how doctors decide to start vancomycin (an antibiotic) when sepsis is suspected, to improve care and avoid unnecessary use.
Atlanta, GeorgiaAges Any age - NCT06361641Recruiting
Study of immune cells in blood cancers
This study looks at immune cells (monocytes) in people with certain blood cancers. Researchers want to understand how these cells behave and change over time. You can join if you are newly diagnosed and haven't started treatment yet.
Angers, Maine et LoireAges 18 years+ - NCT06375993Enrolling by invitationPhase 1
Prula-cel for autoimmune diseases: a phase 1 study
This trial tests a new treatment called prulacabtagene leucel (prula-cel), which is a type of immune cell therapy (CAR T-cells) for people with certain autoimmune diseases. It aims to see if it can reset the immune system and reduce disease activity in conditions like lupus, scleroderma, vasculitis, or myositis.
Redwood City, CaliforniaAges 18–80 - NCT06369753Recruiting
Study on visible belly swelling after meals
This study looks at people whose belly visibly swells after eating. The goal is to understand this condition and track symptoms over time.
Los Angeles, CaliforniaAges 18–80 - NCT06377059Recruiting
Early detection of complications during immunotherapy
This trial uses special equipment to watch for early side effects in people getting CAR T-cell therapy or bispecific antibodies for blood cancers, like lymphoma. It aims to catch problems early so they can be treated faster.
Copenhagen OAges 18 years+ - NCT06366269Recruiting
Acupuncture first for bladder pain syndrome
This trial tests whether acupuncture can help relieve pain and pressure from bladder pain syndrome (also called interstitial cystitis). Researchers want to see if using acupuncture early can improve symptoms better than usual care.
Cleveland, OhioAges 18–89 - NCT06366230RecruitingPhase 1/Phase 2
Adding urea to final dialysis fluid
This trial tests adding urea to the final dialysis fluid for people with very high urea levels. It aims to make dialysis safer and more effective for those who need it urgently.
San Francisco, CaliforniaAges 18 years+
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,055 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.