Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,055 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06291389Recruiting
Airway pressure changes during tummy tuck surgery
This trial tests how changes in airway pressure during tummy tuck surgery affect breathing after the operation. It is for healthy adults having a tummy tuck with muscle tightening.
Tanta, EgyptAges 20–50 - NCT05805202Recruiting
Study rare gene changes in atypical HUS for tailored care
This study looks at how rare gene mutations may explain atypical HUS (aHUS) and how that could guide more personalized treatment. It mainly involves people who have had aHUS affecting blood counts and kidneys.
Ranica, BGAges Any age - NCT06197724Recruiting
MCG test for chest pain patients scheduled for heart scans
This trial is testing a new magnetic heart scan (MCG) to see if it can better detect blockages in people with chest pain that is not a full heart attack. If you are having chest pain and are already scheduled for a heart catheterization or CT scan, this study might help find the cause more accurately.
Jinan, ShandongAges 18 years+ - NCT06274190Recruiting
Better bowel symptom tracking after rectal cancer treatment
This study develops an electronic diary to help track and manage bowel symptoms after rectal cancer surgery or active surveillance. It aims to create personalized care plans to improve your quality of life.
Leuven, Vlaams-BrabantAges 18 years+ - NCT06269965Recruiting
Collagen membrane for rotator cuff repair
This trial tests whether using a special collagen membrane helps improve healing when repairing a torn rotator cuff tendon. It is for people who have a tear in the upper part of the rotator cuff and are having surgery to fix it.
LyonAges 18 years+ - NCT06252948Recruiting
Gut bacteria study for POEMS and related plasma cell disorders
This study looks at the gut microbiome (the bacteria living in your digestive system) in people with POEMS syndrome, multiple myeloma, MGUS, amyloidosis, and healthy household members. It may help researchers understand how gut health relates to these conditions.
Rochester, MinnesotaAges 18 years+ - NCT06265584RecruitingPhase 2
Using ATG to prevent graft-versus-host disease after stem cell transplant
This trial tests if a two-step course of a drug called ATG (anti-thymocyte globulin) can help prevent a serious side effect called graft-versus-host disease (GVHD) after a donor stem cell transplant. It is for people with certain blood cancers who are receiving a reduced-intensity transplant.
Birmingham, AlabamaAges 18–75 - NCT02781922RecruitingPhase 3
Stem cell infusion for single-ventricle heart failure during surgery
This trial tests whether an infusion of heart stem/progenitor cells can improve outcomes for children with a single working heart chamber (single ventricle) who are scheduled for the next surgical stage (Glenn or Fontan). It may help the heart function after surgery, but participation depends on several heart, lung, brain, and overall health safety criteria.
KanagawaAges birth–6 years - NCT05412927Recruiting
Heart device follow-up study for high-risk heart patients
This study monitors how well the AngelMed Guardian® System works after it has already been implanted. It focuses on people at higher risk of heart events, including those with diabetes or kidney problems.
Glendale, ArizonaAges 21 years+ - NCT06246357RecruitingPhase 2
Testing adrenal gland function with a special scan
This trial uses a special PET scan (68Ga-PentixaFor) to check how well your adrenal glands are working if you have high aldosterone or cortisol levels. It helps doctors see if the glands are making too much hormone, which may guide treatment.
Bethesda, MarylandAges 18–120 - NCT06244433Recruiting
Genetic testing for sudden infant death
This study looks for gene changes that might be linked to sudden unexpected infant death. It compares the DNA of babies who died suddenly with DNA from their parents, to find possible inherited causes.
Nantes, Loire-AtlantiqueAges Any age - NCT06230861Recruiting
Quercetin supplement for heart and metabolic health
This study tests whether taking a supplement called quercetin (a natural plant compound) improves heart and metabolic health markers in healthy adults. You'd take the supplement for a period of time, and researchers will measure things like blood sugar and cholesterol.
Preston, LancashireAges 18–65 - NCT02929732Recruiting
Study muscle nerve activity in restless legs
This study looks at how active the nerves are in people with Willis-Ekbom disease (restless legs syndrome) and compares them with people without it. It may help researchers understand what drives symptoms and how the condition works in the body.
MontpellierAges 18–74 - NCT03475498Recruiting
ECG and heart ultrasound before and after pacemaker implantation
This study looks at how heart test results—electrical tracing (ECG) and heart ultrasound (echocardiogram)—change after a device is implanted. It may help doctors better predict who develops PICM (a certain pacing-related heart weakening) and how that affects outcomes.
ChungjuAges 20 years+ - NCT06220474Recruiting
Radiofrequency treatment for stubborn dry eye
This trial tests a non-invasive radiofrequency treatment for people with meibomian gland dysfunction (a type of dry eye) that hasn't improved with standard treatments. It aims to see if this therapy can safely help your eyes feel better.
Hong KongAges 18 years+ - NCT06226220Recruiting
Nerve test for bladder device success in women
This study tests how well a short, in-office nerve evaluation (PNE) predicts the success of sacral neuromodulation—a treatment that uses mild electrical pulses to calm bladder nerves. It is for women with urgency leaking or very frequent urination.
Chicago, IllinoisAges 18 years+ - NCT06208709Recruiting
Carpal tunnel treatment for right hand without surgery
This study tests a new way to treat carpal tunnel syndrome in the right hand without surgery. It may help people with mild to moderate symptoms who have not had recent injections or other treatments.
Tucson, ArizonaAges 18 years+ - NCT06207591Recruiting
Brain implant study for locked-in communication
This study tests a new brain implant (CortiCom) that may help people who are locked-in or nearly locked-in communicate again. It involves surgery to place the device in the brain and requires a caregiver and commitment to follow-up visits.
UtrechtAges 18–70 - NCT05211570RecruitingPhase 1/Phase 2
Study drug AB8939 for AML after prior treatments
This Phase 1/2 study tests AB8939 in people with acute myeloid leukemia (AML) whose disease has come back or did not respond to earlier treatment. It may help researchers find a safe dose and learn whether the treatment can control the leukemia.
Houston, TexasAges 18 years+ - NCT05896826Recruiting
Magnetocardiography to better spot heart attack patients
This study tests whether magnetocardiography—a scan that measures heart signals using magnets—can more accurately identify myocardial infarction (heart attack). It may help doctors detect heart attacks faster and more accurately using safer, non-invasive testing.
Jinan, ShandongAges 18–79 - NCT06193928Recruiting
Long-term safety study of Livmarli in ALGS or PFIC
This study is following patients who are already taking Livmarli (maralixibat) for Alagille syndrome or PFIC to see how safe and effective it is over the long term.
Los Angeles, CaliforniaAges Any age - NCT06194305RecruitingPhase 2
Brain and behavior study of tic therapy for kids
This study tests a behavioral therapy (CBIT) for children with tics. It uses brain scans (MRI and EEG) to see how the therapy works. It may be a good fit for a child who has had tics for at least a year and hasn't had much of this therapy before.
San Diego, CaliforniaAges 10–17 - NCT06188689Recruiting
Testing a new diagnostic test for heart rhythm disorders
This study is evaluating a new diagnostic test for Calcium Release Deficiency Syndrome (CRDS) and related heart rhythm disorders. It aims to find out if this test can accurately identify patients with these conditions, which could lead to better diagnosis and treatment.
San Francisco, CaliforniaAges Any age - NCT06055036Recruiting
Stress reduction for heart health in Black men
This study looks at how reducing stress can improve cardiovascular health in Black men. It involves lifestyle changes and support to help lower your risk of heart disease.
Columbus, OhioAges 18 years+
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,055 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.