Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,195 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06975189RecruitingPhase 2
Reducing radiation in preterm baby lung scans
This trial tests whether using ultrasound instead of X-rays for lung imaging can safely reduce radiation exposure in very premature babies. If your baby needs lung imaging, they may be able to join.
Melbourne, VictoriaAges Up to 1 day - NCT06983028RecruitingPhase 2
Testing atacicept for multiple kidney diseases
This trial tests a medicine called atacicept in adults and children with several types of kidney disease. The goal is to see if it can reduce protein in the urine and help protect kidney function.
Brisbane, CaliforniaAges 2 years+ - NCT06984536RecruitingPhase 2
Lowered immune drug plus mini transplant method for preventing graft vs host disease
This trial tests a new combination of medicines to prevent graft-versus-host disease (GVHD) in patients with leukemia or myelodysplastic syndromes receiving a stem cell transplant from a half-matched donor. It aims to see if using less anti-thymocyte globulin (ATG) plus a simpler post-transplant cyclophosphamide (PTCy) regimen works as well as standard care with fewer side effects.
BeijingAges 12–65 - NCT06991114RecruitingPhase 2
AlloNK and rituximab for relapsing rheumatologic diseases
This trial tests a new natural killer (NK) cell therapy called AlloNK given with rituximab for people with certain autoimmune diseases (rheumatoid arthritis, Sjögren's disease, inflammatory myopathies, or systemic sclerosis) that have not responded well to standard treatments. The goal is to see if this combination can better control the disease.
Tuscaloosa, AlabamaAges 18 years+ - NCT06991387Recruiting
Myofascial release for text neck pain
This study tests a hands-on therapy called myofascial release to see if it can quickly ease neck pain and related symptoms from 'text neck' (pain from using devices too much). If you are a young adult who spends a lot of time on your phone and has neck pain, you might be a good fit.
Karabük, Karabük ProvinceAges 18–40 - NCT06991400Recruiting
A study of a new surgical approach for TTTS and TAPS
This trial tests a new surgical technique for twin-to-twin transfusion syndrome (TTTS) or twin anemia-polycythemia sequence (TAPS). It places a stitch through the amniotic sac during surgery to see if it helps. The study is for pregnant people between 18 and 23 weeks with healthy cervical length and a safe access point for surgery.
Cincinnati, OhioAges 18 years+ - NCT06994676RecruitingPhase 1
Study of CBX-250 for advanced myeloid leukemias
This study tests an experimental drug, CBX-250, for people with certain advanced blood cancers (like AML) that have not responded to standard treatments or have returned. The drug works only for people who have a specific genetic marker (HLA-A*02:01). The goal is to see if it is safe and how well it works.
Duarte, CaliforniaAges 12 years+ - NCT07000227Recruiting
Low FODMAP diet study for IBS or functional dyspepsia
This study looks at how a low FODMAP diet affects people with irritable bowel syndrome (IBS) or functional dyspepsia (FD). It aims to understand why this diet helps some patients and may offer a way to manage your symptoms.
Kuala Lumpur, Kuala LumpurAges 18 years+ - NCT07001891Recruiting
Brain activity study for restless legs syndrome
This study looks at brain connections related to body awareness in people with restless legs syndrome (RLS). It may help researchers understand RLS better.
BordeauxAges 18–70 - NCT07008365RecruitingPhase 3
Measuring belly pressure and ultrasound to guide fluid removal in heart failure
This trial tests whether using belly pressure and bedside ultrasound can help doctors better manage fluid removal (decongestion) in people hospitalized with heart failure. The goal is to see if this approach leads to better outcomes.
ZaragozaAges 18–100 - NCT07009691Recruiting
Hydrogen water for ME/CFS patients
This trial tests whether drinking hydrogen-rich water can improve heart rate variability (a measure of nervous system function) in people with ME/CFS (myalgic encephalomyelitis/chronic fatigue syndrome). The goal is to see if this simple intervention helps reduce symptoms.
Stony Brook, New YorkAges 18–65 - NCT07010328Recruiting
AI-guided posture training for Parkinson's disease
This trial tests whether a special training program that uses artificial intelligence can help improve posture in people with Parkinson's disease who have a forward bend or lean to one side. If you have Parkinson's and a noticeable postural problem, this might be a way to try a new approach to rehabilitation.
Pavullo nel Frignano, PaviaAges 18 years+ - NCT07013344Recruiting
Link between NT-proBNP and heart artery disease
This study looks at a blood test called NT-proBNP to see if it can help predict how much blockage is in the heart's arteries. It may help doctors better understand heart disease risk.
Milan, ItalyAges 18 years+ - NCT07013903Recruiting
Hydrotherapy for post-COVID recovery
This trial tests if Kneipp hydrotherapy (a type of water treatment) helps people recover from post-COVID syndrome. You would receive this therapy during a rehabilitation stay and answer questions on your smartphone.
Schönau am Königssee, BavariaAges 18 years+ - NCT07015203Recruiting
First trimester combined screening study
This study offers a combined screening test for pregnant women in their first trimester. It helps check for potential health issues early in pregnancy.
Most, CzechiaAges 18 years+ - NCT07016035Recruiting
French translation of a PCOS quality-of-life survey
This study aims to translate and validate a French version of the PCOS questionnaire (mPCOSQ) to measure how PCOS affects your daily life. If you have PCOS, you may help improve care for others by sharing your experience.
ReimsAges 18–45 - NCT07019155Recruiting
DDX41 gene study for families with cancer risk
This study looks at people and families who have changes in the DDX41 gene or similar genes that may increase the risk of cancer. By joining, you can help researchers learn more about these gene changes and how they affect health.
Bethesda, MarylandAges 1 month–120 years - NCT07019519Recruiting
Gut hormones and blood flow in POTS
This study looks at how gut hormones control blood flow after eating in people with POTS. It may help explain symptoms like dizziness and rapid heartbeat after meals.
CopenhagenAges 18–50 - NCT07019857Recruiting
Thymus removal and immunity in infant heart surgery
This study looks at how removing the thymus gland during infant heart surgery affects the immune system. It compares babies who have their thymus removed with those who have heart surgery without removing it, and with babies having other types of surgery.
NantesAges Up to 6 months - NCT07020858Recruiting
FAPI imaging for heart attack risk in blocked arteries
This trial tests whether a special scan called FAPI-PET can predict heart problems in people with a chronic total occlusion (a completely blocked heart artery for at least 3 months). If you have this type of blockage and are planning to have a procedure to open it, this study may help guide your care.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07025421Recruiting
Using vertical positioning for ARDS patients
This study tests whether raising the head of the bed (vertical positioning) can help patients with ARDS breathe better. It may offer a simple, non-drug way to improve oxygen levels.
Birmingham, AlabamaAges 18–80 - NCT07026084Recruiting
Biofeedback training for upper cross syndrome
This trial tests if using biofeedback during exercise can improve muscle strength and posture in people with upper cross syndrome. It may help if you have forward head posture, neck pain for over 3 months, and limited neck movement.
Rawalpindi, Punjab ProvinceAges 25–45 - NCT07027995Recruiting
Food and Fitness with Medicine
This study tests a program that combines nutrition counseling, online grocery support, and exercise sessions for people taking GLP-1 medications. It aims to help manage conditions like high blood pressure, diabetes, high cholesterol, kidney disease, or metabolic syndrome.
Columbus, OhioAges 18 years+ - NCT07031063RecruitingPhase 4
HIV treatment study for people starting therapy
This study compares two HIV medications (DTG/3TC and BIC/TAF/FTC) to see which works better and is safer for people who have never taken HIV treatment before. It may help you find a once-daily pill that controls the virus and has fewer side effects.
Mexico City, AzcapotzalcoAges 18 years+
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,195 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.