Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,055 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07576660RecruitingPhase 3
Dexamethasone for lung injury from sepsis
This trial tests whether the steroid dexamethasone can help people with sepsis who develop acute respiratory distress syndrome (ARDS), a severe lung injury. If you have an infection and need breathing support, this study may help find a better treatment.
Nanjing, JiangsuAges Any age - NCT07573553Recruiting
Rib Mobilization and Posture Exercises for Upper Crossed Syndrome
This study tests whether combining rib mobilization (hands-on therapy to improve rib movement) with posture-correction exercises can reduce neck pain and improve posture in people with upper crossed syndrome (a postural condition causing rounded shoulders and forward head tilt). It may help you understand if this combination therapy works better than standard treatment.
Chak Six Hundred Twenty-four, Khyber PakhtunkhwatAges 20–45 - NCT07573527Recruiting
Online therapy for upper back muscle pain from trigger points
This study tests whether remote physical therapy (done online) can help relieve neck and upper back pain caused by tight knots in your rhomboid muscles. You would receive guided exercises and treatment through video calls instead of visiting a clinic in person.
Karachi, SindhAges 18–35 - NCT07572942Recruiting
Laser vision tests for memory and movement concerns
This study tests whether a special laser-based vision test can help detect early thinking and movement changes in older adults. Researchers want to see if this test is useful for identifying people at risk for cognitive decline before serious memory problems develop.
Balıkesir, BigadiçAges 65 years+ - NCT07573371Recruiting
Understanding bowel changes after rectal cancer surgery
This study helps doctors better understand and treat bowel control problems that can happen after rectal cancer surgery or other rectal treatments. If you've had this surgery or treatment, the study team wants to learn more about your recovery and test new ways to help.
AalborgAges 18 years+ - NCT06729151Recruiting
Botox vs. standard care for bladder pain and sexual health
This study compares the effect of Botox injections into the bladder versus standard care (without injections) on sexual function in women with bladder pain syndrome. It aims to see if Botox can improve both pain and sexual health.
Bethesda, MarylandAges 18–99 - NCT06602167Recruiting
Acupuncture and acupressure to prevent hand-foot syndrome from capecitabine
This trial tests if electroacupuncture combined with self-administered acupressure can prevent hand-foot syndrome, a common side effect of the chemotherapy drug capecitabine. It is for people with gastrointestinal or breast cancer who are starting capecitabine for the first time.
Xining, QinghaiAges 18–85 - NCT06658886Recruiting
Corticosteroid injection vs. paraffin therapy for carpal tunnel syndrome
This trial compares two treatments for carpal tunnel syndrome: an ultrasound-guided corticosteroid injection or paraffin wax therapy. It aims to find which option works better for people with mild to moderate symptoms lasting at least 3 months.
Istanbul, BeylikdüzüAges 18–65 - NCT04699279Recruiting
Statin after aortic surgery to protect heart and organs
This trial tests whether taking a cholesterol-lowering medicine (a statin) after certain aortic surgeries can reduce harmful changes in the heart and other organs. You might benefit by lowering the risk of ongoing damage after your acute aortic condition and surgery.
Guangzhou, GuangdongAges 18–85 - NCT07568015Recruiting
Nerve-targeted treatment for lateral hip pain
This study tests an experimental treatment that targets nerves around the hip to relieve pain on the outside of the hip. It may help people who have tried other treatments without enough relief.
Sun City, ArizonaAges 22–80 - NCT02434445Recruiting
Blood and urine tests to predict kidney failure in cirrhosis
This study checks new blood and urine tests to predict who with advanced liver scarring (cirrhosis) will develop hepatorenal syndrome, a serious kidney problem. The results may help doctors spot risk earlier, especially for people being referred for a liver transplant.
Hong KongAges 18–90 - NCT05168124Recruiting
Therapy or short breaks for chronic fatigue syndrome (CFS/ME)
This study tests whether Acceptance and Commitment Therapy (ACT) or doing brief “micro breaks” can improve symptoms in people with CFS/ME. It checks safety and whether you can follow the online program over the study period.
ZurichAges 18–55 - NCT07560566RecruitingPhase 2
Preventing Hand-Foot Skin Reaction in Liver Cancer Treatment
This study tests whether a topical anti-inflammatory cream (indomethacin) applied preventively to hands and feet can reduce a painful skin side effect called hand-foot syndrome that occurs in advanced liver cancer patients taking sorafenib. If effective, it could help patients tolerate their cancer medication better.
TaipeiAges 18 years+ - NCT07568340Recruiting
Supervised versus home exercises for shoulder impingement
This trial compares two ways to treat subacromial impingement syndrome (a common shoulder condition causing pain with overhead movements): supervised rehabilitation sessions versus exercises you do at home. The goal is to see which approach works better for reducing pain and improving shoulder function.
Kırşehir, KırşehirAges 30–65 - NCT07563764Recruiting
Shock Wave Therapy for Overactive Bladder in Women
This study tests whether low-energy shock wave therapy can reduce frequent urination, nighttime bathroom trips, and sudden urges to urinate in women who also have metabolic syndrome (a combination of conditions like high blood pressure, high blood sugar, and extra belly fat). The therapy is non-invasive and may offer an alternative to medications or injections.
Kaohsiung, TaiwanAges 20–75 - NCT07563101Enrolling by invitation
Understanding Visual Hallucinations in Low Vision Patients
This study investigates Charles Bonnet Syndrome, which causes people with significant vision loss to see things that aren't there (visual hallucinations). Researchers want to better understand why this happens and how it affects patients' quality of life.
RomaAges 40–70 - NCT07563218Recruiting
Online skill-building program for teens and young adults with genetic conditions
This trial tests I-TOPS, an online program designed to help teenagers and young adults with genetic syndromes build practical life skills. You and a parent or caregiver would participate together from home using a computer and internet connection.
Bosisio Parini, LeccoAges 11–39 - NCT07562425Recruiting
Knee Strengthening Exercises for Patellofemoral Pain
This study compares three types of thigh muscle exercises to help reduce knee pain in people with patellofemoral pain syndrome (pain around the kneecap). Researchers want to see which exercise style—holding steady, moving through motion, or lowering slowly—works best for your pain.
Elâzığ, MErkezAges 18–50 - NCT04920149RecruitingPhase 2
Mesalamine to help prevent colon cancer in Lynch syndrome
This trial tests whether mesalamine, a medicine used for bowel inflammation, can help prevent colorectal cancer in people with Lynch syndrome who do not currently have cancer. It may help by lowering the chance that new pre-cancer growths form over time.
AalborgAges 30 years+ - NCT06737666RecruitingPhase 1
Tong-Xie-Yao-Fang for Diarrhea-Predominant IBS
This trial tests an herbal formula called Tong-Xie-Yao-Fang for people with diarrhea-predominant irritable bowel syndrome (IBS-D). It aims to see if the treatment helps symptoms and how it works. Healthy volunteers are also needed for comparison.
Beijing, Beijing MunicipalityAges 18–70 - NCT07555691Recruiting
Chinese herbal medicine for fibromyalgia pain relief
This trial tests whether a traditional Chinese herbal medicine called Yishen Shujin Decoction can reduce fibromyalgia pain. Fibromyalgia is a condition causing widespread body pain and fatigue; this study aims to see if this herbal treatment helps relieve those symptoms.
Beijing, Beijing MunicipalityAges 18–75 - NCT07555171Enrolling by invitation
Brain Wave Changes During Fenfluramine Treatment in Lennox-Gastaut Syndrome
This study tracks how brain wave patterns change when children and young adults with Lennox-Gastaut Syndrome (a severe seizure disorder) take fenfluramine, a medication that helps reduce drop seizures. Researchers will use EEG (brain wave recordings) to understand how this treatment affects the brain.
Chicago, IllinoisAges 2–35 - NCT07558538RecruitingEarly Phase 1
Inhaled Growth Factor Treatment for Severe Lung Failure
This early-stage trial tests whether an inhaled medication called recombinant human keratinocyte growth factor-2 (rh-KGF-2) can help patients with acute respiratory distress syndrome (ARDS)—a serious condition where the lungs cannot deliver enough oxygen to the blood. The drug is designed to help repair lung tissue damage.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT06739759Recruiting
Preventing OHSS in PCOS women having ICSI
This trial tests a way to prevent a side effect called ovarian hyperstimulation syndrome (OHSS) in women with PCOS who are having ICSI (a type of IVF). The goal is to make fertility treatment safer for you.
GizaAges 19–42
Hear when a new Down Syndrome trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,055 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.