Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,057 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07285720Recruiting
Language Development in Williams Syndrome
This study looks at how children and adults with Williams syndrome learn language. Researchers want to understand how sounds and word patterns affect language skills in this condition.
AmiensAges 6 years+ - NCT07280091Recruiting
Skin and gut bacteria in Netherton syndrome
This study looks at the bacteria on the skin and in the gut of people with Netherton syndrome, a condition that affects the skin barrier and often causes allergies. It also compares these findings to healthy volunteers to understand how the microbiome might be different.
Paris, Île-de-France RegionAges 10 years+ - NCT07280468RecruitingPhase 4
Personalized sleep apnea treatment for Down syndrome
This study tests if a treatment chosen based on your specific type of sleep apnea works better for people with Down syndrome. It looks for participants who have sleep apnea but are not already using a CPAP machine regularly.
Tucson, ArizonaAges 6 years+ - NCT06051292Recruiting
Testing balloon size for lung pressure measurement in children
This study tests how much air to put in a small balloon in the esophagus (feeding tube-like device) to measure lung pressure more accurately. It is for children on a breathing machine whose settings are stable for the next 2 hours.
AydinAges 1 month–18 years - NCT06885255Recruiting
Fasting and Exercise for Metabolic Syndrome
This study tests whether combining intermittent fasting with exercise can lower inflammation and improve your metabolism and gut health in people with metabolic syndrome.
Erlangen, BavariaAges 18–80 - NCT07278375Recruiting
Comparing treatments for babies with opioid withdrawal
This study looks at different medicine approaches to treat newborns with opioid withdrawal (NOWS). It compares how well babies do with standard care and may help find the best way to manage symptoms and support recovery.
Birmingham, AlabamaAges birth+ - NCT07277582RecruitingPhase 2/Phase 3
Study of a new medicine for long QT syndrome types 2 and 3
This study tests a new medicine called THRV-1268 to see if it can safely improve heart rhythm in people with Long QT syndrome types 2 and 3. It may help reduce the risk of dangerous heart rhythm problems.
Scottsdale, ArizonaAges 15 years+ - NCT07277673Recruiting
Exercise plus talk therapy for impotence in men with metabolic syndrome
This trial tests if adding aerobic exercise to cognitive behavioral therapy (talk therapy) can help treat impotence in men who have metabolic syndrome and drink heavily.
Giza, DokkiAges 35–45 - NCT07270549RecruitingPhase 1/Phase 2
Gene therapy trial for children with CTNNB1 syndrome
This trial tests a one-time gene replacement therapy given into the fluid around the brain to help children with CTNNB1 neurodevelopmental syndrome. The goal is to see if replacing the faulty gene can improve development and reduce symptoms.
LjubljanaAges 2–12 - NCT07275190Recruiting
Machine learning to tell apart two rare diseases
This trial uses computer models (machine learning) to help doctors better distinguish between two rare conditions that both cause high levels of a certain white blood cell (eosinophil). The goal is to make diagnosis faster and more accurate, which could lead to more targeted treatment.
PaviaAges 18 years+ - NCT07276568Enrolling by invitationEarly Phase 1
Hepatocyte-like cell injection for small liver syndrome
This early-phase trial tests an injection of lab-grown liver cells into the stomach muscle to prevent or treat small-for-size syndrome, a condition where a partial liver graft is too small. It may also help people with acute or chronic liver failure.
Beijing, ProvinceAges Any age - NCT07277257RecruitingPhase 4
New dry eye treatment for people with Sjögren's syndrome
This study tests a new treatment for dry eye disease caused by Sjögren's syndrome. It may help people who still have dry eye symptoms even when using artificial tears.
Venice, FloridaAges 18 years+ - NCT07261787RecruitingPhase 4
Surfactant given in 1 vs. 5 minutes for very preterm babies
This trial compares giving a breathing treatment (surfactant) over 1 minute versus 5 minutes to help very premature babies born before 28 weeks. The goal is to see which timing helps the baby's breathing and heart rate stabilize better.
GrazAges birth–3 days - NCT05521451Recruiting
Study for adults with heart rhythm problems
This trial is a “clinical cohort” study, meaning it follows adults with certain heart rhythm issues to understand them better. Your participation may help researchers learn what to expect and how best to support people over time.
HamburgAges 18 years+ - NCT05581147Recruiting
Thyroid health in Klinefelter syndrome
This study looks at how the thyroid gland works and how it looks on ultrasound in people with classic (non-mosaic) 47,XXY Klinefelter syndrome. It may help doctors understand thyroid-related problems in this condition by comparing test results, symptoms, and imaging.
RomaAges 1–80 - NCT07251790Recruiting
Better breathing support for very preterm babies
This trial tests different ways to help very preterm babies when they are first taken off a breathing machine and switched to CPAP. It aims to find the safest and most effective breathing support to help them breathe on their own.
Melbourne, VictoriaAges birth+ - NCT07253298Enrolling by invitation
Kegel exercises with biofeedback for bowel recovery after rectal cancer surgery
This trial studies whether doing Kegel exercises with biofeedback (a technique that helps you see how your muscles are working) can improve bowel function, reduce emotional distress, and boost quality of life after rectal cancer surgery.
TaipeiAges 18 years+ - NCT07254299Recruiting
Hypnosis for ICU recovery and wellbeing
This study tests whether hypnosis sessions during an ICU stay can improve mental and physical recovery after a serious illness. It aims to reduce long-term problems like anxiety, depression, and memory issues.
GenevaAges 18 years+ - NCT07251673Recruiting
Study of Dravet syndrome in children with SCN1A gene changes
This study follows children with Dravet syndrome caused by a specific SCN1A gene change to understand how the condition develops over time. It may help families know more about what to expect.
Paris, Ap-hp / DRCIAges 6 months–21 years - NCT07259252Recruiting
Flu vaccine study for heart attack or unstable angina patients
This study tests whether getting a flu vaccine helps people who recently had a heart attack or unstable angina (acute coronary syndrome). It looks at whether vaccination can reduce future heart problems.
Wuhan, HubeiAges 18–80 - NCT07248748Recruiting
Alexander technique for upper cross syndrome in teens
This study tests whether the Alexander Technique, a method that helps improve posture and reduce muscle tension, can help teenagers with upper cross syndrome (a common posture problem where the shoulders round forward and the head juts out). It may help them feel better and move more easily during school and daily activities.
Lahore, Punjab ProvinceAges 13–16 - NCT07243327Recruiting
Shockwave therapy vs standard rehab for hip pain
This trial compares two treatments—shockwave therapy and conventional physical therapy—for long-lasting pain on the outside of the hip, often called trochanteric pain syndrome. It aims to find which option works better for people whose hip pain has persisted for months.
IstanbulAges 18–65 - NCT07248371Recruiting
Validating multi-omics for metabolic syndrome diseases
This study is testing a new way to look at health information (multi-omics) to better understand conditions related to metabolic syndrome, like diabetes or heart disease. It may help doctors find more personalized treatments.
TaoyuanAges 20 years+ - NCT07248267Recruiting
Vojta therapy for children with Down syndrome
This study is testing a therapy called Vojta therapy to see if it helps children with Down syndrome move better and walk more easily. It compares the therapy to other supportive care.
Lahore, Punjab ProvinceAges 2–10
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,057 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.