Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,057 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07248267Recruiting
Vojta therapy for children with Down syndrome
This study is testing a therapy called Vojta therapy to see if it helps children with Down syndrome move better and walk more easily. It compares the therapy to other supportive care.
Lahore, Punjab ProvinceAges 2–10 - NCT07244068Recruiting
Mat Pilates for kids with upper crossed syndrome
This trial tests if Mat Pilates can reduce pain and improve posture in school-going children with a specific forward head and rounded shoulder condition called upper crossed syndrome. It may help your child feel better and stand straighter.
Lahore, Punjab ProvinceAges 8–16 - NCT07248124Recruiting
Studying muscle response in carpal tunnel syndrome
This study looks at how your muscles react during a specific test for carpal tunnel syndrome. It aims to better understand the condition and could help improve diagnosis.
TarbesAges 18 years+ - NCT07244133Recruiting
Powerball exercise for kids with Down syndrome
This trial tests whether using a Powerball (a small exercise ball) can improve hand strength and coordination in children with Down syndrome. It may help with daily tasks and motor skills.
Lahore, Punjab ProvinceAges 6–10 - NCT07243821Recruiting
Metabolic syndrome and prediabetes study
This study looks at people with metabolic syndrome or prediabetes to understand how these conditions affect health. You may qualify if you have at least three signs of metabolic syndrome or if your blood sugar levels are higher than normal.
Taipei, Zhongzheng DistAges 18 years+ - NCT06794008RecruitingPhase 2
CAR-T cell therapy for hard-to-treat autoimmune diseases
This trial tests a new treatment using your own immune cells (called CAR-T cells) designed to target and attack cells that cause autoimmune diseases. It is for people with lupus, Sjögren's syndrome, inflammatory myopathy, scleroderma, Behcet's disease, ANCA-associated vasculitis, IgG4-related disease, antiphospholipid syndrome, or thrombotic thrombocytopenic purpura who have not improved with standard therapies.
Beijing, Beijing MunicipalityAges 18–65 - NCT04507997Recruiting
Study of the natural course of Angelman syndrome
This study follows people with Angelman syndrome to understand how their symptoms and development change over time. It may help researchers better describe the condition and support future treatments.
Los Angeles, CaliforniaAges Any age - NCT07236658Recruiting
Using AI to detect arm problems after breast cancer surgery
This trial uses artificial intelligence (a computer program) to help predict arm and shoulder problems that can happen after breast cancer surgery. It aims to find these issues early so they can be treated better.
AnkaraAges 18 years+ - NCT07230847Recruiting
Healing of drug-coated vs. standard stents in high-bleeding-risk patients
This trial compares two types of stents (a drug-coated stent and a standard drug-eluting stent) in people with acute coronary syndrome who also have a high risk of bleeding. It uses a special camera to look at how the artery heals one month after the stent is placed.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07236801RecruitingPhase 1
Cell therapy for hard-to-treat autoimmune diseases
This trial tests a new cell therapy called YTS109 for people with several autoimmune diseases that have not improved with standard medications. It aims to see if this treatment can help control the disease when other treatments have failed.
Xuzhou, JiangsuAges 18–65 - NCT07236762RecruitingPhase 1
YTS109 cell therapy for severe autoimmune diseases
This trial tests a new cell therapy called YTS109 for people with severe autoimmune diseases like lupus, Sjögren's syndrome, systemic sclerosis, inflammatory myopathy, vasculitis, and antiphospholipid syndrome. It's for those whose disease hasn't improved with standard treatments.
BengbuAges 18–65 - NCT06909656Recruiting
Brain Activity Study in Tourette Syndrome with Deep Brain Stimulation
This study looks at brain activity in people with Tourette syndrome who are already receiving deep brain stimulation (a treatment that uses electrical pulses to help control tics). The goal is to learn more about the brain signals linked to tics, which could help improve future treatments.
BordeauxAges 16 years+ - NCT07235215Recruiting
Testing Vivatlac for Irritable Bowel Syndrome
This study tests a product called Vivatlac to see if it can help people with Irritable Bowel Syndrome (IBS). If you have moderate-to-severe IBS and haven't taken probiotics or antibiotics recently, you may be able to join.
JarocinAges 18–65 - NCT07233421Enrolling by invitation
Blood sugar levels in children with Long QT syndrome on beta-blockers
This study looks at how often low blood sugar (hypoglycemia) happens in young children with Long QT syndrome who take beta-blocker medicine. It may help doctors understand if these children need extra monitoring.
HelsinkiAges Up to 7 years - NCT07238465RecruitingPhase 3
Nervous system and heart function in Down syndrome
This study looks at how the nervous system controls heart rate and blood pressure in adults with Down syndrome. It involves some simple tests, like blood draws and placing a small tube in an arm vein, plus possibly some cold water or exercise tasks.
Aurora, ColoradoAges 18–50 - NCT07232134RecruitingPhase 3
Treating AML in children with Down syndrome
This trial tests a treatment plan for children with Down syndrome who have been diagnosed with acute myeloid leukemia (AML) or a related bone marrow condition. The goal is to see how well the therapy works and to help guide doctors in choosing the best approach.
MoscowAges 1 day–18 years - NCT05463757Recruiting
Oral drugs for advanced or multiple basal cell skin cancer
This study registers people in the Netherlands who have certain types of basal cell skin cancer and take an oral hedgehog-blocking medicine. It may help doctors understand how well these tablets work and how patients do in real life.
Nijmegen, GelderlandAges Any age - NCT05461898Recruiting
Rehabilitation program for adults with Guillain-Barré syndrome
This trial studies whether an inpatient rehabilitation program can help people with Guillain-Barré syndrome. It may be useful if you need structured therapy and support during recovery.
Vila Nova de GaiaAges 18 years+ - NCT05521529Recruiting
Study of Cushing’s symptoms before and after treatment
This study looks at how Cushing’s syndrome affects people before treatment and what changes after treatment. It may help researchers understand what to expect and improve care for adults with newly diagnosed Cushing’s syndrome.
Aarhus, StateAges 18 years+ - NCT07227363Recruiting
Keto diet for PCOS symptoms pilot study
This study tests if a keto diet can improve symptoms of PCOS. You'll follow your normal routine while researchers monitor changes.
Columbus, OhioAges 18–40 - NCT07229521Recruiting
Nattokinase for heart, gut, sleep, and brain health in metabolic syndrome with sleep issues
This study tests whether a supplement called nattokinase can improve heart health, sleep, thinking, and gut bacteria in people with metabolic syndrome and mild-to-moderate sleep apnea. If you have a larger waist, blood pressure or blood sugar issues, or imbalanced cholesterol, and have been diagnosed with mild or moderate sleep apnea, you may be eligible.
TaipeiAges 18 years+ - NCT07223905Recruiting
Cognitive and walking training for memory and mobility risk
This study tests a combined brain and walking exercise program for older adults who have normal thinking but show early signs of thinking or memory problems and slower walking. The goal is to see if this training can improve memory and movement, and potentially prevent further decline.
Kansas City, KansasAges 65 years+ - NCT07225231Enrolling by invitation
Home EEG monitoring for fenfluramine treatment in dravet and lgs
This trial tests whether a reduced, home-based EEG monitoring device can help doctors safely adjust the dose of fenfluramine, a treatment for seizures in Dravet syndrome and Lennox-Gastaut syndrome. Participation may help find the right dose with fewer hospital visits.
Louisville, KentuckyAges 3 years+ - NCT06912282Recruiting
Deep brain stimulation for Meige syndrome
This study tests if a new deep brain stimulation approach using one electrode on both sides of the brain can help control the muscle spasms of Meige syndrome. It is for people whose symptoms have not improved enough with standard treatments.
Shanghai, Shanghai MunicipalityAges 18 years+
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,057 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.