Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,173 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06499285RecruitingPhase 3
Study of elritercept for anemia in low-risk MDS needing transfusions
This trial tests an investigational drug called elritercept for adults with a specific type of low-risk MDS (myelodysplastic syndromes) who have anemia (low red blood cells) and need regular blood transfusions. The goal is to see if elritercept can reduce or eliminate the need for transfusions.
Duarte, CaliforniaAges 18 years+ - NCT06501196RecruitingPhase 1
Study of BH-30236 for leukemia and high-risk MDS
This trial tests an experimental drug, BH-30236, for people with acute myeloid leukemia (AML) or a high-risk form of myelodysplastic syndrome (MDS) whose cancer has come back or stopped responding to treatment. It aims to see if the drug can help control the disease.
Duarte, CaliforniaAges 18 years+ - NCT06502015Recruiting
Biomarkers in nervous system autoimmune diseases
This study looks for biomarkers (biological clues) in people with autoimmune diseases of the nervous system. It aims to discover better ways to diagnose and treat these conditions.
WuhanAges 18 years+ - NCT06502145RecruitingPhase 1
Iadademstat with hypomethylating agent for MDS
This trial tests a new oral medication (iadademstat) combined with a standard therapy called a hypomethylating agent for people with higher-risk myelodysplastic syndromes (MDS) or related blood cancers. The goal is to see if the combination is safe and effective.
Milwaukee, WisconsinAges 18 years+ - NCT06506630Recruiting
Coenzyme Q10 for metabolic syndrome risk
This trial tests whether taking Coenzyme Q10, a natural supplement, can improve heart health markers in people who have or are at high risk for metabolic syndrome. Metabolic syndrome is a group of conditions like high blood sugar, high blood pressure, and belly fat that raise your risk for heart disease and diabetes.
ShenzhenAges 30–90 - NCT06507007Recruiting
Inner ear function in Turner syndrome
This study looks at why some people with Turner syndrome have inner ear problems. It uses MRI and CBCT scans to understand the genetic and epigenetic causes.
HerningAges 18–60 - NCT06507267Recruiting
Pain and symptoms in pelvic congestion syndrome
This study looks at how pain and other symptoms relate to a condition called pelvic congestion syndrome, which happens when veins in the pelvis become enlarged. It may help doctors better understand and treat this cause of long-term pelvic pain.
IstanbulAges 18–50 - NCT06509464Recruiting
High-intensity interval training for women with central obesity
This study tests whether high-intensity interval training can improve the severity of metabolic syndrome in women who carry extra weight around their belly. It may help you understand how exercise affects your overall health.
GizaAges 25–45 - NCT06509633Recruiting
Pain education and rehab for carpal tunnel syndrome
This study tests whether combining a special type of pain education with standard rehabilitation helps people with moderate to severe carpal tunnel syndrome feel better and improve hand function. It aims to help you understand your pain and recover.
Lahore, Punjab ProvinceAges 20–50 - NCT06509594Recruiting
Exercises for neck pain from Upper Crossed Syndrome
This study compares two types of exercises—scapular stabilization exercises and eccentric muscle energy techniques—to see which works better for neck pain caused by Upper Crossed Syndrome. It's designed for people ages 18 to 35 with neck pain that isn't spreading into the arms or head.
Sargodha, Punjab ProvinceAges 18–35 - NCT06510868Recruiting
MDS risk study for NET patients before or after PRRT
This study looks at the risk of developing Myelodysplastic Syndrome (MDS), a blood disorder, in people with Neuroendocrine Tumors (NET) who are treated with Peptide Radionuclide Therapy (PRRT). It involves a simple blood test to check for genetic changes linked to MDS. Participating can help understand and potentially prevent this side effect.
Toronto, OntarioAges Any age - NCT06511362Recruiting
Balance or strength training for front knee pain
Researchers want to see which type of exercise program better helps people with front knee pain. You will do either balance challenge training or strengthening exercises to see which reduces your pain more.
Lahore, Punjab ProvinceAges 15–30 - NCT06512493Recruiting
South East Netherlands Heart Registry
This is a heart registry that collects information from all patients to get a complete picture of heart care in the region. By including everyone, it aims to improve future treatments without bias.
Heerlen, LimburgAges Any age - NCT06512584RecruitingPhase 3
Study of PJ009 for short bowel syndrome patients needing IV nutrition
This trial tests a new medicine called PJ009 for people with short bowel syndrome who need intravenous (IV) nutrition support. It aims to help reduce the need for IV nutrition. To join, you must have been dependent on IV nutrition for at least six months and be on a stable schedule.
Beijing, Beijing MunicipalityAges 14 years+ - NCT06513611Recruiting
Immune and hormone markers in acute coronary syndrome prognosis
This trial looks at how your body's immune system, hormones, and inflammation affect recovery after a heart attack or unstable angina. It may help doctors better predict outcomes for people with acute coronary syndrome.
Buenos AiresAges 21 years+ - NCT06515184RecruitingPhase 3
Coenzyme Q10 for Gulf War illness study
This study tests whether coenzyme Q10 (a natural supplement) can improve symptoms of Gulf War illness, such as fatigue and body pain. It involves taking the supplement or placebo for several months, with regular check-ins via Zoom and a few blood draws at a local lab.
La Jolla, CaliforniaAges 50 years+ - NCT06515652Recruiting
Herbal vs standard medicines for metabolic syndrome
This study compares herbal medicines to standard medications for people with metabolic syndrome—a group of conditions like high blood pressure, high blood sugar, and excess belly fat. The goal is to see if herbs work as well as traditional drugs, with fewer side effects.
Karachi, SindhAges 35–65 - NCT06518005RecruitingPhase 2
Gene therapy for severe Crigler-Najjar syndrome
This trial tests a new gene therapy called GNT0003, given after a pre-treatment to help it work, for people with severe Crigler-Najjar syndrome. The goal is to see if it can reduce the need for daily light treatments.
ClamartAges 18 years+ - NCT06519006Recruiting
Pelvic floor exercises after rectal surgery
This trial tests whether doing pelvic floor exercises after a type of rectal surgery called 'low anterior resection' can help prevent bowel problems known as Low Anterior Resection Syndrome (LARS). It may help you maintain better bowel control after surgery.
Banská BystricaAges 19 years+ - NCT06526013Recruiting
Cholesterol self-testing after a heart attack
This trial tests if people who recently had a heart attack can use a home cholesterol test to check if their LDL cholesterol is on target. The goal is to help you manage your cholesterol better and lower your risk of another heart problem.
Leipzig, SaxonyAges 18 years+ - NCT06526741Recruiting
Alport Syndrome Patient Registry
This registry collects health information from people with Alport syndrome to help researchers better understand the condition and improve future treatments.
Scottsdale, ArizonaAges birth+ - NCT06527768Recruiting
Helping with metabolic syndrome and kidney disease through lifestyle changes
This study tests a program that uses WeChat to help people with metabolic syndrome and chronic kidney disease make healthy lifestyle changes. They want to see if this support can improve health and slow down kidney problems.
Chengdu, SichuanAges 18 years+ - NCT06530004Recruiting
Rituximab for childhood nephrotic syndrome: a follow-up study
This study follows children with nephrotic syndrome (a kidney condition causing swelling) who are being treated for the first time with rituximab. It aims to see how well the medication works long-term.
Xiamen, FujianAges 1–18 - NCT06533358RecruitingPhase 2
Testing MT1002 for heart attack patients getting a stent
This study tests an investigational medicine called MT1002 in people who have had a heart attack and are about to get a stent (PCI). The goal is to see if MT1002 helps prevent further heart problems.
Beijing, Beijing MunicipalityAges 18–85
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,173 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.