Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,057 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07112365RecruitingPhase 4
Study of fenfluramine to prevent SUDEP in Dravet syndrome
This study tests whether the drug fenfluramine can reduce the risk of sudden unexpected death (SUDEP) in people with Dravet syndrome who have generalized convulsive seizures. It aims to see if a lower dose can still prevent seizures and protect the heart and breathing during a seizure.
Houston, TexasAges 16 years+ - NCT07110961Recruiting
Heart rate test for restless legs diagnosis
This trial tests a new way to diagnose Restless Legs Syndrome (RLS) by looking at your heart rate changes during a simple leg movement test while you're in a sleep study. It may help doctors diagnose RLS more easily.
Bangkok, BangkokAges 18–70 - NCT06966752Recruiting
Comparing two breathing supports for preterm babies with breathing problems
This study compares two types of breathing support (CPAP and NIPPV) for preterm babies with breathing problems. It aims to find which method works better for helping babies breathe easier.
Vilnius, Vilnius CountyAges birth–10 months - NCT06967038RecruitingPhase 1/Phase 2
Natural killer cell therapy for high-risk lymphoma with Sjogren's syndrome
This trial tests a new type of immune cell therapy using natural killer cells to treat people who have both high-risk lymphoma and primary Sjogren's syndrome. The goal is to see if these cells can safely and effectively fight the lymphoma while managing the autoimmune condition.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT07102849Enrolling by invitation
Studying bone marrow failure with biospecimens and data
This study analyzes blood, bone marrow, and medical information from people with bone marrow failure syndromes (BMFS) and healthy volunteers to better understand these conditions and find new ways to help patients.
Bethesda, MarylandAges 2–120 - NCT07096102Recruiting
Helping people with metabolic syndrome improve health knowledge
This trial tests a program to help people with metabolic syndrome learn how to find and use health information. The goal is to give you tools to better manage your health.
Beijing, Beijing MunicipalityAges 18–75 - NCT07098754Recruiting
Physical therapy for neck pain and posture improvement
This study compares different physical therapy techniques to improve neck posture and reduce pain in people with myofascial pain syndrome. It may help if you have mild to moderate neck pain from muscle knots and are open to physiotherapy.
Bahawalpur, Punjab ProvinceAges 20–40 - NCT07103850Recruiting
Testing a suicide risk questionnaire in Latin America
This trial is testing a new questionnaire to better understand suicidal crisis. It takes place in a hospital intensive care unit and aims to help doctors identify and support people at risk.
Santiago, Santiago MetropolitanAges 18 years+ - NCT07098936RecruitingPhase 2
Momelotinib for VEXAS syndrome
This trial tests a drug called momelotinib for people with VEXAS syndrome, a rare inflammatory condition. The goal is to see if momelotinib can reduce symptoms and the need for steroids.
AngersAges 18 years+ - NCT07102628RecruitingPhase 3
Early cholesterol treatment after heart attack
This study tests whether giving a new cholesterol-lowering drug, inclisiran, early during a hospital stay after a heart attack can help lower bad cholesterol (LDL) more effectively than usual care. It may reduce the risk of future heart problems.
Capital Federal, Buenos AiresAges 18 years+ - NCT06647927Recruiting
Genetic study for better Brugada diagnosis
This study looks at the genes of people with Brugada Syndrome to find new markers that can help doctors diagnose it more accurately. If you have Brugada Syndrome, joining could help improve understanding and care for this condition.
San Donato Milanese, MilanAges 18 years+ - NCT07090889RecruitingPhase 1
Study of KM-023 for healthy volunteers and Olmsted syndrome patients
This trial tests a new medication, KM-023, first in healthy volunteers to check safety, and then in people with Olmsted syndrome (a rare skin condition causing thick, painful palms and soles). It aims to see if the drug is safe and helpful for those affected.
Chicago, IllinoisAges 18–55 - NCT07091123RecruitingPhase 4
Comparing two treatments for chronic back pain after surgery
This study compares two treatments for long-term back pain after surgery: a spinal cord stimulator (a device that sends mild electrical pulses to your spine) and a pump that delivers pain medicine directly to your spinal fluid. It will look at which treatment you prefer and how well it works over time.
Cleveland, OhioAges 30 years+ - NCT07090460Recruiting
Measuring lung overstretch in prone-position ARDS patients
This study uses a special imaging belt (EIT) to check if the lungs are being overstretched when patients with severe breathing problems are placed on their stomach (prone position). It may help doctors adjust breathing machines more safely.
Bayonne, Centre Hospitalier de La Côte BasqueAges 18 years+ - NCT07087314RecruitingPhase 2
Study of an injection for nephrotic syndrome in children
This study tests an injection (SG301) that targets a protein called CD38 to help children whose nephrotic syndrome keeps coming back or depends on steroids. The goal is to see if the treatment can reduce relapses and the need for steroids.
Hangzhou, ZhejiangAges 6–18 - NCT07090382Enrolling by invitation
Predicting shock risk in heart attack patients
This study uses an AI tool to predict which patients with a heart attack might develop cardiogenic shock, a serious complication where the heart can't pump enough blood. It aims to help doctors identify high-risk patients early.
BratislavaAges 18 years+ - NCT07086755RecruitingPhase 2/Phase 3
Vadadustat treatment for lung injury from infection
This trial tests a pill called vadadustat for people with a serious lung condition called ARDS, which makes it hard to breathe. The drug may reduce inflammation and improve oxygen levels, helping patients recover without needing a breathing tube.
Houston, TexasAges 18 years+ - NCT07090356Recruiting
Soft tissue therapy versus stretching for athletes with piriformis syndrome
This study compares two techniques—instrument-assisted soft tissue mobilization and PNF stretching—to see which works better for reducing pain and improving movement in athletes with piriformis syndrome. It may help if you are an athlete with ongoing buttock or hip pain that makes sitting uncomfortable.
Lahore, Punjab ProvinceAges 18–35 - NCT07083492Recruiting
Detecting iron deficiency in pregnancy and after birth
This study uses a non-invasive test to check for iron deficiency in women during pregnancy and up to 3 months after giving birth. It aims to make detection easier and more comfortable for you.
Würzburg, BavariaAges 18 years+ - NCT07081880Recruiting
Understanding SAPHO syndrome: genetics and immune response
This study looks at the causes of SAPHO syndrome—a rare condition that affects the skin, bones, and joints. Researchers want to understand how genes and the immune system play a role, which may help improve future treatments.
ParisAges 18 years+ - NCT07082712Recruiting
Thyroid issues and heart attack link study
This study looks at whether thyroid problems are connected to heart attacks (acute coronary syndrome). It may help explain why some people have heart issues.
SohagAges 20 years+ - NCT06330350Recruiting
Talking about family planning for genetic skin conditions
This study interviews people with inherited skin conditions (genodermatoses) who want to have children, and the doctors who care for them. The goal is to learn how to better support family planning decisions, like counseling about genetics and pregnancy risks.
Maastricht, LimburgAges Any age - NCT06695429Recruiting
Beetroot juice to prevent kidney damage from contrast dye
This trial tests if drinking beetroot juice can help protect your kidneys from damage caused by the dye used during heart procedures. It is for people hospitalized with a certain type of heart attack who are at moderate to high risk of kidney problems.
CartagenaAges 18 years+ - NCT06977672Recruiting
Yoga for writing skills in children with Down syndrome
This study tests whether a simple yoga pose (Downward Dog) can help children with Down syndrome improve the fine motor skills they need for writing. It is designed for children ages 4 to 8 who can stand and walk on their own.
Lahore, Punjab ProvinceAges 4–8
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,057 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.