Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,173 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06671795Recruiting
ICU Biobank: Learning about recovery after the ICU
This study collects samples and information from people who spent at least two days in the ICU. The goal is to understand long-term health problems that can happen after a serious illness, like muscle weakness or memory trouble.
ViennaAges 18–65 - NCT06673381Recruiting
Blood markers for inflammation in heart attack
This study is checking if a simple blood test (hs-CRP to albumin ratio) can help predict outcomes in people who have had a heart attack or unstable angina but are not getting an immediate balloon/stent procedure. It aims to use inflammation markers to guide better care.
SohagAges 18 years+ - NCT06674707Recruiting
Agility training with foot exercises for kneecap pain
This trial tests whether adding foot exercises to agility training can better relieve long-lasting knee pain (patellofemoral pain syndrome) in adults ages 20 to 40. Eligible participants will have had pain behind the kneecap for over 6 months.
Lahore, Punjab ProvinceAges 20–40 - NCT06677866Recruiting
Group therapy for teens with Fragile X or autism
This trial tests if group cognitive behavioral therapy (CBT) can help teens with Fragile X syndrome or autism spectrum disorder improve social and emotional skills. It looks at how teens with these conditions respond to a structured group program.
RomeAges 13–19 - NCT06680661RecruitingPhase 2
Double cord blood transplant with abatacept for GVHD prevention
This trial tests whether adding abatacept to a double cord blood transplant can prevent graft-versus-host disease (GVHD) in people with certain blood cancers. You may qualify if you have high-risk leukemia or other blood disorders and do not have a matched related or unrelated donor.
Cleveland, OhioAges 18–65 - NCT06681363Recruiting
Leukemia and MDS biobank study at Nantes Hospital
This trial creates a biobank of blood or bone marrow samples from patients with acute myeloid leukemia (AML), acute lymphoblastic leukemia (ALL), or high-risk myelodysplastic syndrome (MDS). It aims to collect samples for future research, which may help develop better treatments.
NantesAges 18 years+ - NCT06683521Recruiting
Understanding the immune system in FPIES
This study looks at how the immune system works in people with Food Protein-Induced Enterocolitis Syndrome (FPIES). It aims to learn more about this condition to improve future diagnosis and treatment.
New York, New YorkAges 1–60 - NCT06684379RecruitingPhase 1/Phase 2
Two Doses of PRS CK STORM for Severe Viral Pneumonia
This study tests a new drug called PRS CK STORM to see if it can safely calm the body's overactive immune response (cytokine storm) in people with severe pneumonia from COVID-19, flu, or RSV who need oxygen. It aims to reduce inflammation and improve recovery.
Alcalá de Henares, MadridAges 18 years+ - NCT06686290Recruiting
Stretching exercises for levator scapulae pain
This trial compares two stretching techniques to relieve chronic neck and shoulder blade pain caused by tight levator scapulae muscles. It may help you if you have had this pain for at least 3 months and have trouble turning or tilting your head.
Daska Kalan, Punjab ProvinceAges 24–59 - NCT06687018Recruiting
Comparing two hand therapies for carpal tunnel relief
This study tests two types of gentle hand and wrist movements (mobilizations) to see which better relieves pain, tingling, and numbness in carpal tunnel syndrome. It may help you if you have these symptoms and are otherwise healthy.
Lahore, Punjab ProvinceAges 20–45 - NCT06690801Recruiting
Nitric oxide breathing gas for children with lung failure
This trial tests whether adding a breathing gas called nitric oxide to standard care helps children with severe lung failure (ARDS) recover faster. It is for children on a breathing machine who still have low oxygen levels.
Los Angeles, CaliforniaAges birth–21 years - NCT06692894Recruiting
Inflammation and Heart Risk in Myelodysplastic Syndromes
This study looks at whether certain signs of inflammation in the blood can help predict heart problems in people with myelodysplastic syndromes (MDS). If you have MDS and are generally well enough to participate, this trial may help doctors better understand and manage your risk of heart disease.
Burlington, VermontAges 18 years+ - NCT06694311Recruiting
Testing CPAP and high-flow oxygen for ARDS
This study tests two types of breathing support—CPAP (a mask that pushes air into your lungs) and high-flow nasal oxygen (a special tube in your nose)—to see which works better for people with ARDS, a serious lung condition. It may help you breathe more easily without needing a breathing tube.
Barcelona, BarcelonaAges 18–80 - NCT06697236Recruiting
Socioeconomic status and recovery after intensive care
This study looks at how your financial and social situation might affect your recovery after a serious ICU illness. You and one close family member or friend will fill out questionnaires to help doctors better understand long-term challenges for ICU survivors.
DijonAges 18 years+ - NCT06702085Recruiting
Lifestyle changes for older adults with tinnitus and metabolic syndrome
This study tests whether lifestyle changes (like diet and exercise) can help older adults who have both metabolic syndrome and chronic tinnitus (ringing in the ears). It is for people 65 and older with class 1 obesity and long-term ear ringing in both ears.
Dokki, Giza GovernorateAges 65–75 - NCT06703788RecruitingPhase 1/Phase 2
Traditional Chinese Medicine Day Care for Metabolic Syndrome
This trial tests a day care program that combines traditional Chinese medicine with regular care for people with metabolic syndrome. It aims to see if this approach helps improve your health better than standard care alone.
TaoyuanAges 20–75 - NCT06704698Recruiting
Pain relief after esophageal surgery: comparing two nerve blocks
This trial compares two types of nerve blocks (paravertebral and epidural) to see which provides better pain relief after esophagectomy. The goal is to find the safest and most effective way to manage pain for patients undergoing this surgery.
Hangzhou, ZhejiangAges 18–80 - NCT06705153Recruiting
Laughter yoga for irritable bowel syndrome
This study tests whether laughter yoga can help reduce IBS symptoms like belly pain and bloating, and also improve mood, sleep, and overall quality of life. You would join video calls where you practice special laughing exercises (no jokes needed) and then answer questionnaires.
Erzurum, YakutiyeAges 18–90 - NCT06705816Recruiting
Cognitive function in Rett syndrome during trofinetide treatment
This study looks at how trofinetide (a medicine for Rett syndrome) affects thinking and memory in people with Rett syndrome. It will follow participants who are starting this treatment through a specific clinic.
Minneapolis, MinnesotaAges 18–99 - NCT06707805Recruiting
Spinal gliding technique for lower cross syndrome
This trial tests a manual therapy technique called sustained natural apophyseal glides (gentle, sustained pressure on the spine) in people with low back pain caused by lower cross syndrome—a pattern where hip flexors and lower back muscles are tight while abs and buttock muscles are weak. If you have lower back pain with a forward-tilted pelvis and meet the age and muscle tightness/weakness criteria, this study may be for you.
Kotli, Azad KashmirAges 30–50 - NCT05791604Recruiting
Study prebiotics and probiotics to help children with Prader-Willi
This trial studies whether taking prebiotics and probiotics can help children with Prader-Willi syndrome manage obesity. It’s testing a gut-focused approach to weight control over the study period.
Shanghai, Shanghai MunicipalityAges 3–10 - NCT07685847Recruiting
Suppository for chronic prostatitis or pelvic pain relief
This trial tests a rectal suppository (Prospidol®) to see if it can relieve pain and other symptoms in men with long-term prostatitis or pelvic pain. It is for men who have not had treatment recently and have no signs of infection or other serious illnesses.
Avellino, AvellinoAges 18–60 - NCT07384715RecruitingPhase 1
GEN3018 for AML or high-risk MDS
This trial tests a new drug called GEN3018 for people with acute myeloid leukemia (AML) or higher-risk myelodysplastic syndrome (MDS) that has come back or not responded to standard treatments. It aims to see if the drug is safe and effective.
AarhusAges 18 years+ - NCT07545759RecruitingPhase 2
Testing brenipatide for IBS with diarrhea symptoms
This study tests whether a new medication called brenipatide can help people with IBS-diarrhea (IBS-D) reduce belly pain and loose stools. IBS-D is a condition where the intestines move too quickly, causing frequent diarrhea and discomfort.
Mesa, ArizonaAges 18–75
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,173 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.