Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,057 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06229769Recruiting
Angelman syndrome natural history study
This study follows people with Angelman syndrome over time to learn more about the condition. You can join if you have a confirmed genetic diagnosis and your caregiver agrees to take part.
Liège, LiègeAges Any age - NCT06884852Recruiting
Preventing pain after mastectomy: nerve block vs. epidural
This study compares two methods to prevent long-term pain after breast cancer surgery: a nerve block using ultrasound guidance or an epidural. The goal is to see which helps women feel less pain months after their mastectomy.
CairoAges 18–65 - NCT07065357Enrolling by invitationPhase 3
A study on a diabetes drug for metabolic syndrome
This trial tests if empagliflozin, a medication typically used for diabetes, can help people with metabolic syndrome (a cluster of conditions like large waist size, high blood sugar, and high blood pressure). It may improve health and reduce the risk of heart disease.
Hong KongAges 18–85 - NCT07069010Recruiting
Palliative care education for ICU staff
This trial studies whether a tele-palliative care education program can reduce burnout in ICU clinicians. It involves completing surveys before and during the program.
AthensAges Any age - NCT06889480Recruiting
Deep brain stimulation for severe Tourette syndrome
This trial tests a surgical procedure using deep brain stimulation to treat severe Tourette syndrome that hasn't improved with other treatments. It may help reduce tics by targeting specific areas in the brain.
Beijing, Beijing MunicipalityAges 18–60 - NCT07057128Recruiting
Do nerve issues occur in shoulder pain syndrome?
This study looks at whether nerve-related symptoms are common in people with subacromial pain syndrome (a type of shoulder pain). You may qualify if you have shoulder pain that has lasted at least 3 months, with moderate to severe pain in the past week, and if you haven't had shoulder surgery or certain other shoulder problems.
Izmir, İzmirAges 19 years+ - NCT06988189Recruiting
Finding hidden heart rhythm problems in adults
This study looks for hidden heart rhythm problems in adults. It involves simple tests to find conditions that might otherwise go unnoticed.
LondonAges 18–100 - NCT07062523RecruitingPhase 1/Phase 2
FAPI PET scan for Sjögren's syndrome inflammation
This study uses a special PET scan (FAPI PET) to look at inflammation in people with Sjögren's syndrome. It helps doctors understand how active the disease is. You may join if you have Sjögren's syndrome or a solid tumor that needs this scan, and you are not on certain medications.
BeijingAges 18–80 - NCT07059715Recruiting
Studying blood flow during heart surgery for vasoplegia risk
This study looks at blood flow in small and large vessels during heart surgery to understand and predict vasoplegic syndrome, a dangerous drop in blood pressure. It may help find patients at risk and improve their care.
ParisAges 18 years+ - NCT07061782Recruiting
Neck stretching techniques for IT workers with upper cross syndrome
This trial compares two types of stretching exercises to see which one helps reduce neck and shoulder pain in IT professionals with upper cross syndrome. It may help you move better and feel less pain from long hours at the computer.
IslamabadAges 20–40 - NCT07045259Recruiting
Exergaming vs. exercise for memory and movement in seniors
This study compares fun video games that get you moving (exergaming) with standard muscle-strengthening exercises. It aims to see which one better helps older adults who have both slower walking speed and memory concerns.
BalıkesirAges 65 years+ - NCT07051733Enrolling by invitation
Health literacy program for metabolic syndrome
This study tests a health information literacy program to help people with metabolic syndrome better understand and manage their health. It aims to see if the program improves how they take care of their condition.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07044804Recruiting
Brain stimulation to improve language in Down syndrome
This trial tests a non-invasive brain stimulation technique to help adolescents and young adults with Down syndrome improve their language skills. It aims to see if this safe method can boost word-finding and speaking ability.
RomeAges 12–21 - NCT07051967Recruiting
Comparing recovery after ICU for pregnant and non-pregnant COVID-19 patients
This study looks at how COVID-19 and respiratory failure affect recovery after intensive care. It compares pregnant patients to non-pregnant patients to learn more about the long-term effects.
BerlinAges 18 years+ - NCT07051954Recruiting
Breathing muscle training for long COVID recovery
This study tests a special breathing and muscle training program to help people with long COVID feel better and move more easily. The training is designed to strengthen the muscles you use to breathe and to improve your daily function.
Ankara, ÇankayaAges 18–65 - NCT07044869Recruiting
Comparing two hand therapies for piriformis syndrome in women
This study compares two gentle hands-on treatments – a 'facilitated positional release' technique and a 'manual myofascial release' technique – to see which better relieves pain from piriformis syndrome in women.
IslamabadAges 25–50 - NCT06825520Recruiting
Studying urges before tics during habit reversal training
This study tests whether a therapy called 'habit reversal training' can help reduce the strong urges that happen before tics. It is for children and teens (ages 8–17) who have at least 3 tics and feel a warning urge before each tic.
Salt Lake City, UtahAges 8–17 - NCT06992752Recruiting
Trial on breathing problems in people with thoracic outlet syndrome
This study looks at whether people with thoracic outlet syndrome (TOS) have different breathing patterns and how that might relate to their symptoms. If you have had TOS pain for more than 6 months, you may be able to help researchers understand this condition better.
Ankara, AltındağAges 18–65 - NCT07039747RecruitingPhase 2
Can a dietary supplement help people with irritable bowel syndrome?
This trial is testing if a dietary supplement can reduce symptoms of irritable bowel syndrome (IBS). You might qualify if you have been diagnosed with IBS, have moderate to severe symptoms, and are between 18 and 75 years old.
Rouen, FranceAges 18–75 - NCT07040748Recruiting
Virtual reality training to boost thinking skills
This trial tests if immersive virtual reality exercises can improve thinking and memory in adults with metabolic syndrome. It may help if you have noticed some cognitive changes and want to try a non-drug approach.
TerrassaAges 45–70 - NCT07034976Recruiting
Radiofrequency treatment for menopause symptoms in breast cancer survivors
This trial tests a non-surgical radiofrequency treatment, combined with pelvic floor exercises, to help with vaginal dryness and other menopause symptoms in breast cancer survivors. It may be an option if you are free of cancer and have bothersome vaginal dryness.
Madrid, MadridAges 18–75 - NCT07038265Recruiting
Personalized cardiac rehab after a heart attack
This study tests a personalized cardiac rehabilitation program for people who have recently had a heart attack. The program is designed to be more patient-centered, helping you recover and lower your risk for future heart problems.
L'Hospitalet de Llobregat, BarcelonaAges 18 years+ - NCT02502162Recruiting
Low-dose naltrexone for complex regional pain syndrome
This trial tests whether low-dose naltrexone can reduce symptoms of complex regional pain syndrome (CRPS), a long-lasting pain condition in an arm or leg. It may help by targeting pain signaling, but you must meet specific CRPS diagnosis and medication rules to join.
Palo Alto, CaliforniaAges 18–70 - NCT04898647Recruiting
Study of blood thickness in Waldenström’s disease
This study looks at “hyperviscosity,” meaning very thick blood, in people with Waldenström macroglobulinemia (WM). Your results may help doctors better understand who needs treatment and what tests should be used, even if thick blood is not found.
AmiensAges 18 years+
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,057 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.