Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,173 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07689396Recruiting
What affects treatment expectations for muscle pain?
This study tests how your expectations about treatment affect your recovery from myofascial pain (a type of muscle pain with tender spots). You will be in physical therapy and answer questions about your pain and outlook.
KonyaAges 18 years+ - NCT07691125RecruitingPhase 4
Growth hormone for adults with short bowel syndrome
This trial tests whether a growth hormone injection (Saizeng®) can help adults with short bowel syndrome. The goal is to see if it improves how your body absorbs nutrients and fluids.
Xiamen, FujianAges 18 years+ - NCT07657312RecruitingPhase 2
Infliximab to prevent side effects during myeloma treatment
This trial tests if infliximab, a drug that calms the immune system, can prevent cytokine release syndrome (a serious side effect) when patients receive teclistamab or talquetamab for multiple myeloma that has returned or not responded to treatment.
Columbus, OhioAges 18 years+ - NCT01311323Recruiting
Testing heart procedures to fully open blocked coronary arteries
This trial compares different ways to treat serious heart artery blockages in people with a recent heart attack or unstable chest pain. It aims to see which revascularization approach works best when doctors think the heart arteries can be fully treated.
Chrzanów, MalopolskaAges 18 years+ - NCT07660913Recruiting
Vibrating therapy for carpal tunnel syndrome
This study tests whether a gentle vibrating therapy (matrix rhythm therapy) can help relieve pain, tingling, and numbness from carpal tunnel syndrome. Participants will receive the therapy, and researchers will track if it improves hand function without surgery or drugs.
IzmirAges 18–60 - NCT06602167Recruiting
Acupuncture and acupressure to prevent hand-foot syndrome from capecitabine
This trial tests if electroacupuncture combined with self-administered acupressure can prevent hand-foot syndrome, a common side effect of the chemotherapy drug capecitabine. It is for people with gastrointestinal or breast cancer who are starting capecitabine for the first time.
Xining, QinghaiAges 18–85 - NCT06612242Recruiting
Early vs. late tracheostomy in Guillain-Barre patients
This trial looks at whether having a tracheostomy (a breathing tube placed through the neck) earlier or later helps people with Guillain-Barre syndrome who need a breathing machine. It reviews past cases to see which timing leads to better recovery.
Kfar SabaAges 18 years+ - NCT06613126Recruiting
App to help parents manage Tourette symptoms in children
This trial tests a smartphone app that helps parents manage their child's Tourette Syndrome symptoms. It may improve how parents care for their child and reduce stress.
Taoyuan CityAges 20–60 - NCT06613490RecruitingEarly Phase 1
CAR NK cells for antibody syndrome and rheumatoid arthritis
This early-phase trial tests whether a new type of immune cell (CAR NK) can treat two conditions: antisynthetase antibody syndrome (a rare autoimmune disease) and rheumatoid arthritis. It's for people whose current treatments haven't worked well enough.
Nanjing, JiangsuAges 18–70 - NCT06614270Recruiting
CAR-NK cell therapy for severe autoimmune diseases
This trial tests a new type of immune cell therapy using modified natural killer cells (CAR-NK) that target a protein called CD19 and produce helpful signals (IL-10 and IL-15). It is for people with certain autoimmune diseases that have not improved with standard treatments or have come back after getting better.
Hangzhou, ZhejiangAges 18–65 - NCT06622915Recruiting
Heart health in kids with kidney condition
This study looks at how different types of nephrotic syndrome affect heart function in children. It may help doctors understand the heart risks in kids who need steroids for a long time compared to those whose condition doesn't respond to steroids.
SohagAges 2–14 - NCT06630650Recruiting
Study of Congenital Myasthenic Syndrome (CMS) Over Time
This study follows people with congenital myasthenic syndrome (CMS) over time to learn more about how the condition changes and to find better ways to measure symptoms. You will not receive any treatment, but your participation helps researchers understand CMS better.
Bethesda, MarylandAges 6 months–99 years - NCT06635213Recruiting
Desensitisation and pain education for carpal tunnel syndrome
This study tests whether desensitisation therapy and pain neuroscience education help people with carpal tunnel syndrome who have a type of pain called 'nociplastic' (pain without clear tissue damage). It aims to reduce pain and improve function.
KütahyaAges 18–65 - NCT06635629RecruitingPhase 2
Desmopressin test for ACTH-dependent Cushing syndrome
This trial studies how well a desmopressin stimulation test works to diagnose ACTH-dependent Cushing syndrome. It compares results from people with possible or recurrent Cushing syndrome and healthy volunteers.
Bethesda, MarylandAges 18–70 - NCT06636513Recruiting
Testing SMT04 for irritable bowel syndrome
This trial tests a new treatment called SMT04 for people with irritable bowel syndrome (IBS), specifically the diarrhea or mixed types. It may help reduce symptoms like abdominal pain and changes in bowel habits.
Singapore, SingaporeAges 21–55 - NCT06641154RecruitingPhase 1/Phase 2
Gene therapy for severe Crigler-Najjar syndrome
This trial tests a gene therapy for children with severe Crigler-Najjar syndrome type I. It aims to reduce the need for daily phototherapy by fixing the faulty gene.
MoscowAges 3 months–10 years - NCT06642831Recruiting
PCOS biomarker study for young women
This study looks for biological markers of polycystic ovary syndrome (PCOS) in young women. If you are between 15 and 25 and have not used hormonal birth control recently, you may be able to help researchers find better ways to diagnose PCOS.
ErlangenAges 15–25 - NCT06647043Recruiting
Can synbiotics help irritable bowel syndrome?
This study tests whether a synbiotic (a mix of good bacteria and fiber) can improve symptoms of irritable bowel syndrome (IBS), especially for people with diarrhea-predominant or mixed type IBS, or functional diarrhea.
Kubang Kerian, KelantanAges 18–70 - NCT06647927Recruiting
Genetic study for better Brugada diagnosis
This study looks at the genes of people with Brugada Syndrome to find new markers that can help doctors diagnose it more accurately. If you have Brugada Syndrome, joining could help improve understanding and care for this condition.
San Donato Milanese, MilanAges 18 years+ - NCT06655844Recruiting
Sana Device for chronic pain from Lyme disease
This study tests the Sana device—a special light and sound tool—to see if it can help reduce chronic nerve pain in people with Post-Treatment Lyme Disease Syndrome. You may be able to join if you have ongoing nerve pain after Lyme treatment and meet a few basic health and medication rules.
New York, New YorkAges 18 years+ - NCT06658886Recruiting
Corticosteroid injection vs. paraffin therapy for carpal tunnel syndrome
This trial compares two treatments for carpal tunnel syndrome: an ultrasound-guided corticosteroid injection or paraffin wax therapy. It aims to find which option works better for people with mild to moderate symptoms lasting at least 3 months.
Istanbul, BeylikdüzüAges 18–65 - NCT06660901Recruiting
Study on cannabis use and vomiting in emergency rooms
This study looks at patients who come to the ER with belly pain or vomiting and uses cannabis, to better understand a condition called cannabinoid hyperemesis syndrome (severe nausea and vomiting caused by long-term cannabis use). If you're eligible, you'll answer a few questions to help doctors learn more.
AngersAges 18–65 - NCT06668805RecruitingPhase 2
Testing vosoritide for children with Noonan syndrome and slow growth
This study tests a medication called vosoritide for children with Noonan syndrome who are still growing slowly despite using human growth hormone. The goal is to see if vosoritide can help them grow taller.
Los Angeles, CaliforniaAges 3–11 - NCT06669949Recruiting
Studying the natural history of SPLIS disease
This study collects health information from people with SPLIS to better understand the condition over time. It may include your siblings if they also have SPLIS, and data from patients who have passed away.
San Francisco, CaliforniaAges Any age
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,173 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.