Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,201 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05030259Recruiting
Study of recovery after thigh artery injuries
This trial looks at outcomes in adults who have injuries to the femoropopliteal (thigh-to-knee) artery. It may help doctors understand what affects recovery and discharge, especially for preventing complications.
Shijiazhuang, HebeiAges 18 years+ - NCT04966624Recruiting
Ultrasound-guided breathing strategy for new focal ARDS
This study tests a way to guide ventilator settings using lung ultrasound pictures in adults with very new, localized ("focal") ARDS. The goal is to see whether this approach improves care for people who just started needing a breathing machine.
DijonAges 18 years+ - NCT04954690Recruiting
Exercise program after kidney transplant for older adults
This trial tests a structured, coached exercise program for people who recently received a living-donor kidney and are coming from dialysis. It may help improve strength and daily function after transplant, especially if starting fitness is difficult.
San Francisco, CaliforniaAges 50 years+ - NCT05609877Recruiting
Testing LISA breathing treatment for very preterm newborns
This trial is studying whether giving a lung “surfactant” medicine through a thin tube (called LISA) helps very premature babies with breathing problems. It aims to see if this approach improves care for babies born around 24 to 30 weeks gestation who still need oxygen support.
AalborgAges 6 months–7 months - NCT05267821RecruitingPhase 2/Phase 3
Testing anakinra to reduce inflammation in pediatric sepsis MODS
This study tests whether a medicine called anakinra can “turn down” harmful inflammation in children with severe illness from sepsis. It aims to improve organ function when multiple organs are starting to fail.
Birmingham, AlabamaAges 1 day–17 years - NCT03040583Recruiting
Study of people with primary Sjögren’s syndrome
This study follows adults with primary Sjögren’s syndrome. It may help researchers understand the condition better by using information from people who have already joined the earlier ASSESS study.
Le Kremlin-Bicêtre, Val De MarneAges 18 years+ - NCT05796388Recruiting
Virtual reality and linaclotide for IBS with constipation
This study tests whether virtual reality (VR) plus linaclotide can improve symptoms and quality of life in adults with IBS-C (IBS with constipation). You may be asked to use VR and take a study medicine, while doctors check that your IBS diagnosis fits strict criteria.
Jacksonville, FloridaAges 18–70 - NCT05604066Enrolling by invitation
MRI scan to study muscle pain stiffness in low back or leg
This study uses a special MRI scan (magnetic resonance elastography) to measure how stiff muscles are in people with long-lasting low back or leg muscle pain. It may help researchers better understand myofascial pain—pain caused by tight, tender spots in muscle.
Rochester, MinnesotaAges 18 years+ - NCT05017051Recruiting
Testing brain function in adults with cerebral palsy
This trial measures how the brain and movement systems work in real-life (everyday) conditions. It may help researchers understand brain-related thinking and control problems in adults, and to compare them with healthy adults.
ClamartAges 18 years+ - NCT04731857Recruiting
Genetic testing results study for rare diseases
This study looks at how well different genetic tests (whole exome/genome sequencing and standard genetic tests) work for diagnosing rare genetic diseases and inherited cancer conditions. It may help confirm which testing approach provides the clearest results for families.
TübingenAges Any age - NCT04738708Recruiting
Phone vs in-person genetic counseling for cancer risk
This study compares two ways of getting genetic counseling—by phone/video or in person—for people who may have hereditary cancer syndromes like HBOC or Lynch syndrome. It may help find which counseling approach works best for understanding results and next steps.
SingaporeAges 21 years+ - NCT04639830Recruiting
Testing how sleep patterns relate to child brain development
This study looks at how a child’s sleep looks on a sleep-monitoring test and how that relates to brain/learning growth over time. It includes some children without known risks and some children with known developmental or learning risks, to better understand sleep’s role.
Bethesda, MarylandAges 6 months–8 years - NCT03991507Recruiting
Study for people with polycystic ovary syndrome (PCOS)
This study is looking for people who have PCOS based on a specific medical diagnosis standard called the Rotterdam criteria. If you match that diagnosis, the study may test treatments or strategies for PCOS and how well they work.
Zhengzhou, HenanAges 18–40 - NCT02812212Recruiting
Test a kidney scan to spot early blockage in newborns
This study checks whether a specific kidney test (a renogram scan) can detect a significant urine blockage early in babies born with ureter-pelvic junction obstruction (a narrow connection between the kidney and ureter). It may help clinicians decide sooner which babies need closer follow-up or treatment.
BordeauxAges 4 weeks–2 months - NCT02621645RecruitingPhase 4
Early vs late treatment for twin reversed blood flow
This study compares two timing approaches for treating a rare twin complication called twin reversed arterial perfusion (TRAP). It aims to see whether starting treatment earlier or later leads to better baby outcomes and safety for the mother.
Houston, TexasAges 18 years+ - NCT02055105Recruiting
Study tests a blood test pattern in children with sepsis
This trial studies how a specific pattern in blood (called “molecular fingerprinting”) changes in children with suspected or developing sepsis. The goal is to help doctors better recognize sepsis early and understand how it progresses, which may improve care.
Phoenix, ArizonaAges 1–18 - NCT07166432Recruiting
New brain stimulation for thinking and balance problems in Cushing syndrome
This trial tests a new, minimally invasive brain stimulation technique for people with Cushing syndrome who have developed a condition called cerebellar cognitive affective syndrome (CCAS). It aims to improve both thinking skills and movement coordination.
BeijingAges 18–85 - NCT03475498Recruiting
ECG and heart ultrasound before and after pacemaker implantation
This study looks at how heart test results—electrical tracing (ECG) and heart ultrasound (echocardiogram)—change after a device is implanted. It may help doctors better predict who develops PICM (a certain pacing-related heart weakening) and how that affects outcomes.
ChungjuAges 20 years+ - NCT06864520Recruiting
GABA supplement for menopause symptoms
This study tests whether a natural supplement containing GABA (a chemical that helps calm the brain) can reduce menopause symptoms like hot flashes, mood swings, and sleep problems. It may be a good option if you are looking for a non-hormonal way to manage your symptoms.
Genova, ItaliaAges Any age - NCT03168802Recruiting
Ultrasound and nerve treatment for facet-joint low back pain
This study tests whether a procedure that uses focused ultrasound (MRgFUS) and/or a radiofrequency nerve treatment can reduce long-lasting low back pain caused by facet-joint arthritis. It may help people whose pain improves strongly after a targeted numbing injection to specific back nerves.
Taipei, Please SelectAges 20–79 - NCT07164638Enrolling by invitation
Predicting fluid overload during prostate surgery
This study uses ultrasound to check for fluid overload in men having prostate surgery with spinal anesthesia. The goal is to see which ultrasound method works best to prevent complications.
TantaAges Any age - NCT06212492Recruiting
Muscle relaxants and stomach positioning for ARDS
This trial tests whether combining two treatments—medications that relax muscles (neuromuscular blocking agents) and lying on your stomach (prone positioning)—can reduce lung damage in people with severe ARDS on a breathing machine.
MarseilleAges 18 years+ - NCT06369584Recruiting
Prone Position for Children on ECMO with Severe ARDS
This trial tests if lying face-down (prone position) helps children with severe ARDS who are already on ECMO, a machine that supports the heart and lungs. It aims to see if this position improves recovery.
Beijing, Beijing MunicipalityAges 1 month–18 years - NCT05263076Recruiting
Uterus transplant trial for women born without a working uterus
This trial studies uterus transplant surgery to help people with “absolute uterine factor infertility” (no working uterus) become pregnant using embryos made by IVF. It checks whether the donated uterus can support pregnancy and safe delivery for participants who meet strict medical and health requirements.
Houston, TexasAges 20–65
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,201 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.