Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,057 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06806345RecruitingPhase 1/Phase 2
Oxygen therapy for insulin resistance after menopause
This trial tests whether hyperbaric oxygen therapy can help reduce insulin resistance in postmenopausal women. It may offer a new way to improve blood sugar control.
Cairo, Cairo GovernorateAges 55–65 - NCT07436312Recruiting
Effect of ultra-processed foods on cancer risk in high-risk people
This trial looks at whether eating less ultra-processed foods can lower cancer risk in people who are already at high risk for cancer. It is part of a larger program called Interception that helps monitor and reduce cancer risk.
AvignonAges 18 years+ - NCT07437391Recruiting
L-carnitine for preterm babies with breathing problems
This trial tests whether giving L-carnitine, a nutrient that helps cells make energy, to premature newborns with respiratory distress syndrome (RDS) can improve their health. It may help their bodies cope better in the NICU.
Muzaffargarh, Punjab ProvinceAges 1 hour–1 day - NCT07437924Enrolling by invitation
Bruxism and pelvic floor health in young women
This study looks at whether teeth grinding (bruxism) is linked to pelvic floor muscle function in young women. If you are 18–30 and either grind your teeth or do not, you may help researchers understand this connection.
KonyaAges 18–30 - NCT07436429Recruiting
Drug-coated balloon for heart attack treatment
This trial tests if a special balloon that releases medication can be used instead of a stent during emergency angioplasty for certain heart attacks. It may help patients who are having a first-time heart attack and are stable enough for the procedure.
ViennaAges 18 years+ - NCT07441525RecruitingEarly Phase 1
CAR-T cell therapy for hard-to-treat autoimmune blood diseases
This early-stage trial tests a new type of immune cell therapy (CAR-T) that targets two proteins, CD19 and BCMA, in people with autoimmune blood diseases like ITP, AIHA, or Evans syndrome that have not responded to standard treatments. It aims to reset the immune system and reduce production of harmful antibodies.
Wuhan, HubeiAges 18–75 - NCT06793904Recruiting
Comparing two ways to measure insulin resistance in PCOS
This study compares two methods (HOMA1-IR and HOMA2-IR) of measuring insulin resistance to see which one better predicts whether women with PCOS will ovulate after treatment. It aims to find a simple blood test that could help guide fertility treatment.
CairoAges 18–35 - NCT05416385Recruiting
Stress echo scan with special contrast to study carotid plaque
This study uses a heart stress ultrasound test, plus a contrast dye, to look for new blood vessel growth inside carotid plaque (the buildup in neck arteries). It may help doctors better judge the risk of stroke and determine which people need closer care.
Calgary, AlbertaAges 18 years+ - NCT07432113Recruiting
Predicting meningitis and encephalitis causes from spinal fluid
This trial tests a method to quickly identify the cause of meningitis or encephalitis by looking at your symptoms and spinal fluid results. It may help doctors choose the right treatment faster.
Porto Alegre, Rio Grande do SulAges 18 years+ - NCT07428837Recruiting
Brain and body exercises vs. Pilates for balance in Down syndrome
This study compares two types of exercise programs to see which one helps kids with Down syndrome improve their balance and stability. One program combines thinking and movement tasks, while the other uses Pilates exercises.
IslamabadAges 8–13 - NCT07428811Recruiting
Mirror therapy for post-stroke shoulder and hand problems
This trial tests whether task-based mirror therapy can help improve shoulder and hand function in people who have had a stroke less than 6 months ago. It focuses on those with moderate to severe stroke symptoms but without severe muscle stiffness or cognitive issues.
Lahore, Punjab ProvinceAges 45–75 - NCT07426172Recruiting
Lactate levels and metabolism in active adults
This trial looks at how high lactate levels (a natural chemical in your body) affect the way your body uses fat and sugar. It is for people with metabolic syndrome who are already physically active.
San Javier, MurciaAges 18–65 - NCT07425769Recruiting
Adapting a program for adults with Down syndrome and caregivers
This study tests a program to help adults with Down syndrome and their caregivers become more active. It aims to improve health and well-being for both.
Kansas City, KansasAges Any age - NCT07432490RecruitingPhase 2
Fucose supplement trial for GLUT1 deficiency
This trial tests whether taking fucose (a type of sugar) can help people with GLUT1 deficiency syndrome, a rare genetic condition that affects how the brain gets energy. If you have ataxia (trouble with balance or coordination) and meet other criteria, this study may be an option for you.
Portland, OregonAges 18 years+ - NCT07433634Recruiting
Tracking recovery after BVN ablation for chronic low back pain
This study looks at how well a procedure called BVN ablation (which uses heat to stop pain signals from the vertebrae) works for people with chronic low back pain that comes from the spine. If you already have this procedure scheduled, researchers will track your recovery and pain relief over time.
Guilford, ConnecticutAges 18 years+ - NCT07431593Recruiting
Study on inflammation markers in obesity
This trial examines how two blood markers, SII and SIRI, relate to health issues linked to obesity. It aims to help doctors better predict and manage conditions like metabolic problems in overweight and obese adults.
VaraždinAges 18 years+ - NCT07426146Recruiting
Diet for PCOS: Low glycemic, high fiber study in Yunnan
This study tests if a diet low in quickly digested carbs (low glycemic index) and high in fiber can help women with PCOS who are overweight. You'll follow this eating plan and not change your exercise, to see how it affects your PCOS symptoms over several months.
Gengma County, YunnanAges 19–40 - NCT07429227Recruiting
Gut health and heart disease: a probiotic study
This trial tests whether natural extracts and probiotics can improve gut health in people who have had a recent heart attack (Acute Coronary Syndrome). It uses special exams to measure changes in gut bacteria.
Peschiera del Garda, VeronaAges 30–70 - NCT07429773Recruiting
Immune markers in stubborn pelvic pain
This study looks at the immune system's response in people with chronic pelvic pain that hasn't gotten better with first treatments. By measuring certain immune markers, the researchers hope to better understand why the pain persists and find new ways to help.
Nice, Alpes-MaritimesAges 18–40 - NCT07426991Recruiting
Multiple sclerosis, thinking, sleep, and tiredness study
This study looks at how multiple sclerosis (MS) affects your thinking, sleep, and tiredness. It compares people with MS who have at least mild fatigue to people without MS who also have sleep problems, to understand these issues better.
DüsseldorfAges 18–79 - NCT06684119Recruiting
Testing best breathing tube pressure for children on a ventilator
This trial uses a special imaging tool (EIT) to find the best air pressure in the breathing tube for children on a ventilator. It aims to improve lung function in children with a lung condition called PARDS.
Los Angeles, CaliforniaAges birth–18 years - NCT04399200Recruiting
Study apnea after stroke to prevent new heart events
This trial looks at sleep apnea (breathing pauses during sleep) in people soon after a first stroke or a TIA, to see if it can be linked to new cardiovascular (heart/blood vessel) events. It also aims to make sure you can safely follow the study and rehabilitation plan.
GrenobleAges 18–85 - NCT07422688Enrolling by invitation
Using light scans to find heart artery blockages
This trial uses a special light-based scan (optical coherence tomography, or OCT) to help doctors see inside your heart arteries and find the exact blockage causing your heart attack. It may help guide treatment more precisely.
GenkAges 18 years+ - NCT07424898Enrolling by invitation
Lactose Intolerance and Gut Health Study
This study looks at how lactose intolerance is linked to gut health. It is for adults with ongoing digestive issues like bloating, pain, or diarrhea, to see if their gut lining may be more sensitive.
IstanbulAges 18–70
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,057 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.