Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,196 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04276922Recruiting
Creative arts program to reduce healthcare burnout
This study tests a creative arts program to help reduce burnout symptoms in people who work in hospitals. If you’re feeling emotionally drained or disconnected at work, participating may help you build coping and well-being skills.
Aurora, ColoradoAges 18–85 - NCT04282187RecruitingPhase 2
Decitabine plus targeted drugs for advanced blood cancer blast phase
This Phase 2 trial tests whether adding decitabine to one of three targeted medicines (ruxolitinib, fedratinib, or pacritinib) can improve outcomes in people with advanced myeloproliferative neoplasms that are progressing to a blast phase. It may help control the disease by combining blood-cancer chemotherapy with drugs that block disease-driving signaling.
Seattle, WashingtonAges 18 years+ - NCT04299893RecruitingPhase 2/Phase 3
Ozone treatment for chemotherapy nerve pain
This trial tests whether ozone therapy can reduce painful nerve damage caused by chemotherapy. It is for adults with ongoing moderate-to-severe pain in the hands or feet after chemotherapy.
Las Palmas de Gran Canaria, Las PalmasAges 18–100 - NCT04302116Recruiting
Vigabatrin plus high-dose steroid versus vigabatrin alone
This trial tests whether adding a high-dose steroid (prednisolone) to vigabatrin works better than vigabatrin alone for infants with infantile spasms. It may help reduce seizures and improve early development, but your child’s prior treatments and health conditions must fit the study rules.
Ratchathewi, BangkokAges 2 months–1.2 years - NCT04308564Recruiting
Study of lab and clinic data in antiphospholipid patients
This study looks at lab results and clinic information in people who have antiphospholipid antibodies. The goal is to better understand these antibody-positive conditions and what happens over time, which may help improve care.
LilleAges 18 years+ - NCT04319627RecruitingPhase 3
Statins to prevent new blood clots after leg clot or lung clot
This trial tests whether taking a statin (rosuvastatin) after a recent leg blood clot (DVT) and/or lung blood clot (PE) can lower the chance of future venous clots. You might benefit if you’re at risk for more clotting and can take the study medication safely.
Calgary, AlbertaAges 18 years+ - NCT04330651Recruiting
Extra-support machine for heart patients after surgery
This study looks at using an external life-support machine after heart surgery. It may help patients who need temporary extra support while the heart and body recover.
FlorenceAges 18–80 - NCT04336644Recruiting
Checks heart rhythm continuously or intermittently during treatment
This study compares two ways of monitoring your heart rhythm while you start certain cancer treatments. It may help doctors detect heart rhythm changes earlier and decide which monitoring approach is better.
St Louis, MissouriAges 18 years+ - NCT04344912Recruiting
Study of COVID-19 effects on heart emergency care
This study looks at how the COVID-19 outbreak affected care for people admitted to the cardiac intensive care unit. It may help hospitals improve how they plan and respond during major outbreaks.
ParisAges 18 years+ - NCT04361994Recruiting
GErman Italian Spanish Takotsubo Registry
This registry studies people who have been diagnosed with Takotsubo syndrome (a temporary heart condition that can mimic a heart attack). It helps researchers learn about who gets it, what happens over time, and what factors may affect recovery.
Lübeck, Schleswig-HolsteinAges 18 years+ - NCT04366388Recruiting
Testing a new way to check frailty in hospitalized seniors
This trial studies a new tool that helps doctors measure “frailty” in older adults who are hospitalized. It may help hospitals identify risks earlier and tailor care for seniors who are more vulnerable.
Vancouver, British ColumbiaAges 65 years+ - NCT04371042Recruiting
Study of liver disease and genes in people with fatty liver
This study collects information about metabolic and unexplained (cryptogenic) liver disease and looks at “omics” tests, which are lab tests that measure patterns in blood or tissue to learn what drives the disease. It may help researchers better understand fatty liver and related serious complications, like liver scarring and liver cancer.
Roma, Rome/lazio/italyAges 18 years+ - NCT04395196RecruitingPhase 2
Prenatal choline for pregnancy after alcohol exposure
This trial tests whether taking a choline supplement during pregnancy can reduce harmful effects on the baby when a person drinks heavily while pregnant. It may help support healthier pregnancy and baby outcomes for those who meet the study’s drinking and nutrition criteria.
Cape Town, Western CapeAges 18–45 - NCT04398992Recruiting
Anti-inflammatory add-on treatment after certain aortic conditions
This study tests whether an “add-on” anti-inflammatory approach can help after surgery for certain problems affecting the aorta (the body’s main artery) soon after symptoms begin. It may be designed to reduce inflammation-related complications in people who are treated quickly and can join follow-up.
Beijing, Beijing MunicipalityAges 18 years+ - NCT04399200Recruiting
Study apnea after stroke to prevent new heart events
This trial looks at sleep apnea (breathing pauses during sleep) in people soon after a first stroke or a TIA, to see if it can be linked to new cardiovascular (heart/blood vessel) events. It also aims to make sure you can safely follow the study and rehabilitation plan.
GrenobleAges 18–85 - NCT04407780Recruiting
Cardio-oncology patient registry
This is a registry (a research database) for people who are being followed in cardio-oncology, which means care for heart problems related to cancer or cancer treatments. It may help doctors better understand these conditions and improve future care.
ParisAges 18 years+ - NCT04416581RecruitingPhase 4
Compare two stomach-protecting medicines to prevent bleeding
This trial compares a potassium-competitive acid blocker to a proton pump inhibitor to help prevent stomach or intestinal bleeding in people at high risk who take blood-thinning medicines. It may help reduce dangerous GI bleeding while you stay on heart/stroke medicines.
AnyangAges 19 years+ - NCT04436991Recruiting
Testing antibiotic doses in older adults in the emergency room
This study looks at how best to dose certain antibiotics in people age 75 and older who are admitted to a geriatric (older-adult) hospital unit. It aims to measure antibiotic levels in the body to see whether dosing can be improved for older patients.
GhentAges 75 years+ - NCT04436978RecruitingPhase 4
Best blood thinner plan for atrial fibrillation after stent
This study compares different blood-thinner (“antithrombotic”) strategies in people with atrial fibrillation or flutter who recently had a stent placed (PCI). It aims to find a plan that lowers clot risk while keeping bleeding risk as low as possible.
AalstAges 18 years+ - NCT04444128Recruiting
Testing heart risk assessment using MRI T1 mapping
This study checks whether an MRI heart scan measure called “T1 mapping” can improve how doctors estimate heart disease risk in everyday people. You may join if you’re an adult and can have a contrast-enhanced heart MRI safely.
Frankfurt am Main, HesseAges 18 years+ - NCT04445571Recruiting
Surfactant given with a thin tube or catheter device
This trial tests two ways of giving surfactant (a lung medicine) to very premature babies with respiratory distress syndrome. It may help show which method works better and is safer for helping newborn lungs breathe.
StockholmAges Up to 2 days - NCT04446858Recruiting
Ultrasound tests to study kidney failure in liver pressure disease
This trial studies whether special non-invasive ultrasound scans can help predict outcomes in people who have both liver-related high blood pressure in the veins (portal hypertension) and kidney failure. It may help doctors choose better monitoring and treatment for this specific combination of problems.
BonnAges 18–100 - NCT04448145Recruiting
Study why COVID lasts after recovery
This study looks at what factors may make COVID-19 symptoms or infection effects last after someone has recovered. It also collects certain body samples to better understand why this persistence happens.
New York, New YorkAges 7 years+ - NCT04460859Recruiting
Testing an electrical monitor in moderately severe lung failure
This trial tests a bedside breathing and lung-monitoring method that uses small electrodes on the chest. It is meant for people with moderate to severe ARDS (a serious lung inflammation problem) who are on a breathing machine, to help guide care.
São PauloAges 18 years+
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,196 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.