Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,057 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06790875Recruiting
Comparing two ventilator settings for lung health in ARDS
This study tests two methods of adjusting a ventilator to see which one may better protect the lungs of patients with ARDS. It will help doctors learn how to set the machine to reduce strain on the lungs.
Wuhan, HubeiAges 18–80 - NCT05946850Recruiting
Caudal pain block study for adults with chronic pain
This trial looks at giving a specific pain procedure called caudal analgesia to adults with long-term (chronic) pain. It may help reduce pain after the procedure, and it will compare results for people who can safely receive it.
Surrey, British ColumbiaAges 20–99 - NCT05883358Recruiting
Treating kratom withdrawal with clonidine or buprenorphine
This trial studies medicines (clonidine and/or buprenorphine) to help manage kratom dependence and kratom withdrawal symptoms. You may be asked to regularly track withdrawal symptoms in diaries to help the study team monitor safety and response.
Surrey, British ColumbiaAges 20–99 - NCT06793774Recruiting
Using CT scans and AI to evaluate heart artery risk
This study uses a CT scan of your heart (CCTA) and advanced computer analysis to see how well it can predict heart risks compared to detailed inside-look tests (IVUS, OCT, NIRS). If you have chest pain and have had certain heart scans, this trial may help doctors understand your condition better.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07460037Recruiting
Brain signal study for speech recovery after stroke or injury
This trial uses a special brain-mapping test called high-density ECoG to study how people who have lost speech due to stroke, brain tumor, or ALS can be helped by reading brain signals when they imagine speaking. It may lead to new devices that let people with severe speech problems communicate using only their thoughts.
Hangzhou, ZhejiangAges 20–80 - NCT07460856Recruiting
Can Cranberries Improve Your Gut and Metabolic Health?
This study tests if eating cranberries can improve your gut health and metabolism. It’s for people who are overweight and have early signs of metabolic problems, like high blood sugar or high triglycerides.
Québec, QuebecAges 25–70 - NCT07459790RecruitingPhase 2/Phase 3
A new treatment for interstitial cystitis with Hunner's lesions
This study tests a new treatment for women with interstitial cystitis (also called painful bladder syndrome) who have Hunner's lesions (specific sores in the bladder lining). The goal is to see if the new treatment can reduce pelvic pain, frequent urination, and other symptoms.
MoscowAges 18–65 - NCT07456020Recruiting
Measuring awareness after brain injury in the ICU
This study checks how awake and aware you are using two standard checklists (CRS-R and SECONDs). It's for people with recent brain injuries in intensive care who are still very dependent.
Hessisch Oldendorf, Lower SaxonyAges 18 years+ - NCT06148818Recruiting
Neck exercises for jaw pain relief
This study tests whether special neck exercises can help reduce jaw pain in people who have both jaw (TMJ) problems and neck pain. If you have had jaw pain for at least 3 months and also have achy neck pain, you may be able to join.
TrabzonAges 18–55 - NCT06799091Recruiting
Nerve stimulation for fibromyalgia relief
This trial tests whether a nerve stimulation technique can help reduce fibromyalgia symptoms. It is open to women with a confirmed diagnosis of fibromyalgia who have had symptoms for at least three months.
GizaAges 20–45 - NCT03382158Recruiting
Learn about DICER1-related tumors through a patient registry
This registry collects information about people with known or suspected DICER1-related conditions, including certain rare chest and other tumor types. It helps doctors and researchers understand these conditions better and may support future studies.
Minneapolis, MinnesotaAges birth–100 years - NCT07451821Recruiting
Thinking and attention in functional neurological disorder
This study looks at a condition called 'cognitive disengagement syndrome' in people with Functional Neurological Symptom Disorder (also known as conversion disorder). Researchers want to understand how thinking and attention may be affected, and they need both people with the disorder and healthy volunteers to participate.
Elâzığ, ElâzığAges 18–65 - NCT07444723RecruitingPhase 2/Phase 3
New imaging to find parathyroid tumors before surgery
This study tests two advanced imaging techniques (PET/MR and PET/CT) to find overactive parathyroid glands or tumors that need surgery. Participants get a special scan before surgery to help surgeons locate the problem more accurately.
Bethesda, MarylandAges 18–100 - NCT07446985Recruiting
Exercise and diet for PCOS with asthma
This study tests whether adding physical exercise to a diet plan helps women who have both PCOS and asthma. It may help you lose weight and manage your symptoms.
Giza, DokkiAges 20–30 - NCT07445516Recruiting
Bite adjustment for TMD: long-term follow-up
This trial follows up with people who previously had a dental bite adjustment (occlusal equilibration) for TMD (jaw or face muscle/joint pain). It compares their long-term results with a group that received a 'sham' (fake) procedure.
Santiago de Compostela, A CoruñaAges 18–85 - NCT07446634Recruiting
Jaw advancement surgery for sleep apnea
This study tests jaw advancement surgery for people with obstructive sleep apnea who haven't been helped by CPAP or mouthpieces. It looks at whether moving the jaw forward can improve breathing during sleep.
Falun, Dalarna CountyAges 18–70 - NCT07452263Recruiting
Frailty screening tool for older adults before major surgery
This study tests a simple frailty screening tool in older adults before major surgery. It aims to see if the tool helps identify patients who might need extra support before and after their operation.
Reykjavik, HofudborgarsvaedidAges 70 years+ - NCT07448935Recruiting
Understanding a gene's role in AL amyloidosis and POEMS
This study looks at how a specific gene (IGLV1-44) affects two rare diseases: AL amyloidosis and POEMS syndrome. It involves a blood draw and possibly a bone marrow sample to learn more about how the gene works in these conditions.
PaviaAges 18–99 - NCT07449572RecruitingPhase 1
Safety study of HT31-1 for healthy volunteers
This trial tests a new drug called HT31-1 to see if it's safe in healthy people. It looks at how the drug moves in your body and if it causes side effects. This is a first step before testing it in patients with ARDS (a serious lung condition).
Richmond, VirginiaAges 18–65 - NCT06752018Recruiting
Inflammation, heart disease, and diabetes study
This study looks at how inflammation affects heart disease and diabetes. It may help find new ways to prevent or treat these conditions.
AarhusAges 18 years+ - NCT06805448RecruitingPhase 1/Phase 2
Stem cell treatment for dry mouth in Sjögren's disease
This trial tests if injecting fat-derived stem cells into the salivary glands can help relieve dry mouth in people with Sjögren's disease. It aims to improve saliva flow and reduce discomfort.
CopenhagenAges 18 years+ - NCT06805409Recruiting
Ultrasound test for kidney risk in ARDS patients
This study tests whether a special ultrasound of the veins (VExUS) can help predict kidney injury in people with severe breathing problems who are on a breathing machine and receiving medicine to support their blood pressure.
Créteil, Val de MarneAges 18–100 - NCT07439848RecruitingPhase 1/Phase 2
Stem cells for severe lung injury from sepsis
This trial tests if adding stem cells or their growth liquid to standard sepsis treatment helps adults with severe breathing problems. It may improve recovery for those whose family agrees to the study.
Jakarta Pusat, DKI JakartaAges 40 years+ - NCT07444567RecruitingPhase 3
Continuing benralizumab treatment after a previous study
This trial lets people who completed an earlier benralizumab study and are benefiting from the medicine keep receiving it. The goal is to provide ongoing access while we continue to monitor safety and effectiveness.
Aurora, ColoradoAges 6 years+
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,057 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.