Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,057 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07420322Recruiting
Testing brain stimulation for depression and related symptoms
This trial studies a non-invasive brain stimulation treatment for people with depression or related symptoms that haven't improved with standard treatments. The goal is to see how well it works in real-world settings.
MünchenAges 18 years+ - NCT07416968RecruitingPhase 4
Low dose tadalafil vs solifenacin for overactive bladder in women
This study compares two medications—tadalafil (a daily pill for blood flow) and solifenacin (a pill that relaxes the bladder)—to see which works better for women with overactive bladder (OAB), which causes sudden, strong urges to urinate. It will help doctors find a treatment that may have fewer side effects.
Shibīn al Kawm, Al-MinūfiyyahAges 18–75 - NCT05474196Recruiting
Monitoring pressures in the lungs for people with ARDS
This trial studies how pressure measurements from a special breathing and temperature monitoring system relate to fluid outside the lung blood vessels in people with ARDS. It may help doctors understand what those measurements mean and how to monitor patients more accurately.
Le Kremlin-BicêtreAges 18 years+ - NCT06802952Recruiting
Personalized magnetic brain stimulation for early psychosis risk
This study tests whether a type of magnetic brain stimulation (rTMS) can help people who are at high risk for psychosis. The stimulation is personalized using a brain scan called magnetoencephalography (MEG) to target the right areas.
ShanghaiAges 13–35 - NCT04033224Recruiting
Blood-filter treatments for ICU patients with kidney and organ failure
This trial tests a specific type of blood-filter treatment in critically ill ICU patients who have acute kidney injury and/or failure of other organs. It aims to see whether these filters can improve care by supporting kidney function and/or calming harmful inflammation.
Empoli, FirenzeAges Any age - NCT04580680Recruiting
Testing a blood-filter treatment in critically ill ICU patients
This study looks at an add-on blood-filter treatment used in the ICU to help remove harmful substances like waste products, inflammation signals, or toxins from the blood. Results may help doctors understand whether this approach improves care and how it should be used.
FlorenceAges Any age - NCT06123962Recruiting
Identifying lung injury subtypes to guide treatment
This study looks at different patterns in patients with a severe lung condition called ARDS, to better understand why some respond to treatments differently. You may help doctors learn how to personalize care.
BeijingAges 18 years+ - NCT07416201Recruiting
Study of Immune System Aging in Down Syndrome
This study is looking at how the immune system changes over time in people with Down syndrome, and how it may be affected by removal of the thymus gland. The goal is to understand why people with Down syndrome may age faster or have different immune health.
Bethesda, MarylandAges 1–120 - NCT07412860Recruiting
Eye drop test for moderate to severe dry eye
This trial tests a new eye drop (FBV_01) compared to a standard hyaluronic acid eye drop for people with moderate to severe dry eye. The goal is to see if the new drop provides better relief.
Cagliari, CAAges 18 years+ - NCT07413731Recruiting
Medication tapering with spinal cord stimulation
This trial tests how changing your pain medications while using a spinal cord stimulator affects your nervous system. It may help people with chronic lower back pain find the best way to manage their pain and reduce reliance on strong drugs.
WilrijkAges 18 years+ - NCT07409337Recruiting
Self-acupressure for period pain and PMS
This trial tests if doing acupressure on yourself can reduce period pain and premenstrual symptoms over about six months. It might help if you have painful periods and are looking for a non-medicine option.
Niğde, MerkezAges 18–30 - NCT07411716Recruiting
Children's liver disease registry in Canada
This study creates a registry to track children with specific genetic liver conditions that cause cholestasis (slow bile flow). Being in the registry helps researchers better understand these diseases and may help future patients.
Calgary, AlbertaAges Up to 18 years - NCT07415720Recruiting
Artichoke and Mediterranean diet to prevent type 2 diabetes
This study tests whether a special extract from artichoke by-products, combined with a Mediterranean diet, can help prevent type 2 diabetes in people who are at risk. It aims to improve how your body handles sugar and insulin.
Pamplona, NavarreAges 18–75 - NCT07413874Recruiting
Music therapy over video for depression and hormone disorder
This trial tests if telehealth music therapy can help adults who have both an endocrine autoimmune disease and depression. You'll join sessions from home using Zoom.
Boone, North CarolinaAges 18–65 - NCT07411833Enrolling by invitation
Brain stimulation for stress and burnout in university staff
This study tests whether a gentle brain stimulation technique called tDCS can help reduce stress and burnout in university staff. It involves 10 sessions of treatment, and researchers will check if it improves how you feel at work.
Almada, Setúbal DistrictAges 18 years+ - NCT07408505Recruiting
New appetite drug for weight loss in advanced pancreatic cancer
This trial tests a new form of a drug (nano-megestrol acetate) to help people with advanced pancreatic cancer who are losing weight and have poor appetite. It aims to see if it can improve cachexia, a condition of severe weight loss and muscle wasting.
JinanAges 18–75 - NCT07399730Recruiting
Study of ravulizumab outcomes in Polish aHUS patients
This study looks at how well patients with aHUS in Poland are doing after treatment with ravulizumab (Ultomiris). It is for people who have already received this drug through the national program and agree to share their health information.
GdanskAges 18 years+ - NCT07403188Recruiting
Long-Term Follow-Up Study for KYV-101 Participants
This long-term follow-up study checks on the health and safety of people who have already received the experimental cell therapy KYV-101 in a previous clinical trial. It is a way for them to be monitored over time without any additional treatments.
Denver, ColoradoAges 18 years+ - NCT07400341RecruitingPhase 2
Romiplostim vs rhTPO for platelet recovery after transplant
This trial compares two drugs, romiplostim and rhTPO, to help increase platelet counts after a stem cell transplant in people with MDS or aplastic anemia. The goal is to see which drug works better at reducing the need for platelet transfusions.
Suzhou, JiangsuAges 18–65 - NCT07403929Recruiting
Fermented grape juice for fibromyalgia symptoms
This trial tests whether drinking fermented grape juice can help relieve fibromyalgia symptoms like pain and cramping. If you are a woman between 20 and 40 with mild excess weight and fibromyalgia, you may be eligible.
Istanbul, IstanbulAges 20–40 - NCT07403201RecruitingEarly Phase 1
Combination therapy for PCOS
This trial is testing a combination treatment for PCOS. It is looking for married women who are willing to join the study.
Yogyakarta, DIYAges Up to 45 years - NCT07404384Enrolling by invitation
Slow breathing and resistance exercise for fibromyalgia
This study tests whether combining slow breathing exercises with light weightlifting (biceps curls) can help women with fibromyalgia feel better. It focuses on improving symptoms through a simple home-based routine.
Málaga, MálagaAges 18 years+ - NCT07402642Recruiting
Early Education to Lower Heart Attack Risk Factors
This trial tests if personalized education after a heart attack helps patients lower their future risk of heart problems. It focuses on people who had an emergency procedure to open blocked arteries.
Las Palmas de Gran Canaria, Las PalmasAges 18 years+ - NCT06161636Recruiting
Studying hand movement to diagnose Parkinson's early
This trial looks at how analyzing hand movements might help doctors tell the difference between Parkinson's disease and other similar conditions early on. It may help improve diagnosis so patients get the right care sooner.
Montreal, QuebecAges 50–75
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,057 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.