Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,173 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06112418Recruiting
Personalized vs standard care to prevent heart attacks
This trial compares two ways to prevent heart attacks and strokes: one uses a special heart CT scan to guide care, the other uses standard risk factors like blood pressure and cholesterol. You may be eligible if you are older (men over 55, women over 65) and have diabetes, prediabetes, or metabolic syndrome.
Chandler, ArizonaAges 55 years+ - NCT06430554Recruiting
Personalized ventilation for ARDS patients on breathing machines
This trial tests a personalized ventilation method that adjusts how the breathing machine delivers air based on your lung's air and blood flow match. It aims to improve breathing for people with moderate to severe ARDS who are already on a ventilator and will be placed on their stomach.
Nanjing, JiangsuAges 18–85 - NCT06990477Recruiting
EIT-guided breathing machine settings for ARDS
This trial tests a special monitoring technique called EIT (electrical impedance tomography) to help doctors set the best breathing machine pressure for people with ARDS. It may help improve oxygen levels and protect the lungs.
Hefei, AnhuiAges 19–90 - NCT05881005Recruiting
NAC for fatty liver in people with active Cushing’s
This study tests whether NAC (a supplement/medicine) can improve liver health in adults who have active Cushing’s syndrome and fatty liver disease. It may help if your excess stress hormone levels are affecting your liver.
AngersAges 18 years+ - NCT07322705Recruiting
Reducing groin injury during hip scope surgery
This study tests a new way to position patients during hip keyhole surgery to reduce injury to the groin area from pulling. If you are having hip arthroscopy for a condition called femoroacetabular impingement, this trial might help make your recovery smoother.
Beijing, Beijing MunicipalityAges 15–60 - NCT06560242Recruiting
Tracking early sound perception in Fragile X syndrome
This study uses safe brain monitoring (fNIRS and EEG) to see how infants with Fragile X syndrome process sounds compared to other infants. The goal is to find early signs of hearing or perception issues.
Cincinnati, OhioAges 6 months–2.2 years - NCT07633366Recruiting
Understanding ARDS Through Lung Fluid and Imaging Analysis
This study examines lung fluid samples and imaging scans from patients on breathing machines to better understand acute respiratory distress syndrome (ARDS), a serious lung condition. Researchers hope this will help doctors diagnose and treat ARDS more effectively in the future.
Vienna, State of ViennaAges 18 years+ - NCT06327984Recruiting
Sex hormones and inflammation in heart disease
This study looks at how sex hormones and inflammation affect chest pain and heart disease. It aims to improve care for people with coronary artery disease.
LondonAges 16 years+ - NCT06329999Recruiting
CMGV for recurrent AML and high-risk MDS
This study tests a new treatment called CMGV for adults whose acute myeloid leukemia (AML) or high-risk myelodysplastic syndrome (MDS) has returned or is not improving. It is for people who may be older or have had other blood disorders.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06333990RecruitingPhase 3
Quetiapine for concussion symptoms in veterans
This study tests whether quetiapine (a medication that can help with mood, sleep, and thinking) reduces ongoing concussion symptoms in veterans who had a mild traumatic brain injury (mTBI) at least 6 months ago. You may join if you are already taking at least three medications for your brain or mental health symptoms and have some PTSD symptoms.
Albuquerque, New MexicoAges 18–65 - NCT06336070Recruiting
Power training for metabolic health in postmenopausal cancer survivors
This trial compares two types of exercise—muscle power training and metabolic power training—to see which better improves your body's ability to use energy and control heart function. You may qualify if you are a postmenopausal woman who has had breast cancer and is not currently active.
Valencia, ValenciaAges 35–75 - NCT06338488Recruiting
Dry needling for shoulder pain from muscle knots
This trial tests if dry needling (inserting thin needles into muscle knots) can reduce shoulder pain caused by a condition called myofascial pain syndrome. It may help if you have a specific muscle knot in your shoulder blade area and significant pain.
Kütahya, TürkiyeAges 18–80 - NCT06338514Recruiting
Dry needling for upper back muscle pain
This study tests if dry needling helps reduce shoulder pain caused by muscle knots in the upper back. It may be an option if you have not had recent back surgery or treatments.
KütahyaAges 18–80 - NCT06339957Recruiting
Rheumatology diet study for arthritis and related conditions
This study looks at how diet affects people with different types of arthritis and related autoimmune conditions. If you are a UCF Health patient between 18 and 65, you may be able to help researchers learn more about which foods help or worsen symptoms.
Orlando, FloridaAges 18–65 - NCT06341673Recruiting
Nerve stimulation for bladder symptoms in multiple sclerosis
This trial tests a nerve stimulation treatment (TTNS) to improve bladder symptoms like urgency or frequent urination in people with multiple sclerosis. It is a randomized controlled study comparing this approach to a control, and aims to see if it can reduce bothersome bladder issues.
Khobar, Eastern ProvidenceAges 18 years+ - NCT06347926Recruiting
Light therapy for menopause symptoms in breast cancer
This study tests a light-based treatment (photobiomodulation) to see if it improves sexual quality of life for women with breast cancer who have menopause-related vaginal symptoms that the usual moisturizers did not relieve.
Montpellier, HéraultAges 18 years+ - NCT06350110RecruitingPhase 1/Phase 2
CAR T cells for lupus
This trial tests a new type of CAR T cell therapy for people with active lupus that has not responded to other treatments. It uses specially engineered cells to target and eliminate certain immune cells that are causing the disease, with the goal of reducing symptoms and preventing flare-ups.
Beijing, Beijing MunicipalityAges 18–90 - NCT06353607Recruiting
Genetics of aortic aneurysm and dissection
This study looks at the genetic reasons behind aortic aneurysms and sudden aortic tears. By studying people who had surgery at the University Hospital Basel, researchers hope to find inherited patterns that could help predict and prevent these serious conditions.
BaselAges 18 years+ - NCT06355583RecruitingPhase 2
Gut bacteria transplant before stem cell transplant
This trial tests whether giving a transplant of healthy gut bacteria (fecal microbiota transplant) before a stem cell transplant can improve outcomes for people with certain blood cancers or bone marrow disorders.
Birmingham, EnglandAges 18 years+ - NCT06357780Recruiting
Comparing two breath-timing methods for breathing masks in adults
This study compares two ways of timing a breathing mask's support to match your own breaths. If you're in the ICU or ER and need help breathing for at least 2 more hours, this trial may test which method works better.
IzmirAges 18 years+ - NCT06360302Recruiting
Exercise and insulin resistance in dialysis patients
This study looks at how exercise affects muscle metabolism and insulin resistance in people on dialysis, compared to those with metabolic syndrome and healthy individuals. It aims to find blood markers that could help assess insulin resistance in dialysis patients.
MontpellierAges 40–75 - NCT06360965Recruiting
Acupoint patch for pelvic pain after PID
This trial tests a skin patch treatment (acupoint application) placed on specific points of the body to help relieve ongoing pelvic pain from pelvic inflammatory disease. It may be a good option if you have moderate pain and ultrasound findings of tubal thickening or fluid.
BeijingAges 18–50 - NCT06363253Recruiting
Gut bacteria study in obesity and muscle loss
This study looks at the bacteria in your gut (the microbiome) to understand how they relate to obesity and muscle loss. Researchers will collect stool samples to analyze the gut bacteria, which may help find new ways to treat metabolic diseases.
SingaporeAges 21–99 - NCT06365502Recruiting
Preventing future heart attacks with drug-coated balloon
This trial tests whether a balloon coated with medicine (drug-coated balloon) can prevent future heart attacks by treating high-risk plaques in arteries that are not the one that caused your current heart attack. You may qualify if you already had a stent placed and have another mildly blocked artery with certain vulnerable features.
Beijin, Beijing MunicipalityAges 18–80
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,173 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.